KEGG   ENZYME: 1.3.5.5
Entry
EC 1.3.5.5                  Enzyme                                 
Name
15-cis-phytoene desaturase;
phytoene desaturase (ambiguous);
PDS;
plant-type phytoene desaturase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With a quinone or related compound as acceptor
Sysname
15-cis-phytoene:plastoquinone oxidoreductase
Reaction(IUBMB)
15-cis-phytoene + 2 plastoquinone = 9,15,9'-tricis-zeta-carotene + 2 plastoquinol (overall reaction) [RN:R09652];
(1a) 15-cis-phytoene + plastoquinone = 15,9'-dicis-phytofluene + plastoquinol [RN:R09653];
(1b) 15,9'-dicis-phytofluene + plastoquinone = 9,15,9'-tricis-zeta-carotene + plastoquinol [RN:R09654]
Reaction(KEGG)
R09652 R09653 R09654;
(other) R04786 R04787
Substrate
15-cis-phytoene [CPD:C05421];
plastoquinone [CPD:C02061];
15,9'-dicis-phytofluene [CPD:C19765]
Product
9,15,9'-tricis-zeta-carotene [CPD:C19764];
plastoquinol [CPD:C16693];
15,9'-dicis-phytofluene [CPD:C19765]
Comment
This enzyme is involved in carotenoid biosynthesis in plants and cyanobacteria. The enzyme from Synechococcus can also use NAD+ and NADP+ as electron acceptor under anaerobic conditions. The enzyme from Gentiana lutea shows no activity with NAD+ or NADP+ [1].
History
EC 1.3.5.5 created 2011
Pathway
ec00906  Carotenoid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K02293  15-cis-phytoene desaturase
Genes
ATHAT4G14210(PDS3)
ALY9306401
CRB17878253
CSAT104719032 104723803 104732250
EUSEUTSA_v10024795mg
BRP103835193 103863556(PDS)
BNA106361559 106390766 106439724 106445763
BOE106336235 106342038
RSZ108818861 108848374
THJ104822231
CPAP110807915
CIT102577966
PVY116106846
MINC123220978
TCC18602597
GRA105777064
GHI107902032 107914777
GAB108464199
DZI111307810
EGR104414241
GMX100127420 547970(PDS1)
GSJ114382350 114394421
PVUPHAVU_001G264200g
VRA106778315
VAR108318944
VUN114194529
CCAJ109797685
APRC113851561
CAM101499699
LJALj0g3v0087419.1(Lj0g3v0087419.1) Lj0g3v0087419.2(Lj0g3v0087419.2) Lj0g3v0087419.3(Lj0g3v0087419.3) Lj0g3v0087419.4(Lj0g3v0087419.4) Lj0g3v0087419.5(Lj0g3v0087419.5)
ADU107482407
AIP107638266
AHF112740925 112795647
LANG109327051 109344116
FVE101297926
RCN112198323
PPER18788299
PMUM103322563
PAVI110747173
PDUL117635990
MDM103400619
PXB103960366
ZJU107422207
MNT21393372
CSV101209155
CMO103494596(pds)
BHJ120085447
MCHA111025543
CMAX111470788 111479159
CMOS111439193 111457519
CPEP111790786 111800496
RCU8280960
JCU105639092
HBR110672897
MESC110615521
POP7462030 7462440
PEU105107692
PALZ118040701
JRE108996675
QSU111992705 112031551
QLO115949670
TWL119987623 120005757
VVI100240685(PDS1)
VRI117922015
SLY544073(pds)
SPEN107014359
SOT102577582(PDS)
SSTN125857795
CANN107861625
NTA107788963 107816873
NSY104248773
NTO104107035
NAU109223965
INI109192580
ITR115996903
SIND105157894 105174760
OEU111400390
EGT105975735
SSPL121794128 121801249
HAN110913080
ECAD122588872
LSV111915314
CCAV112510531
DCR108222758
CSIN114306113
BVG104899658
SOE110787181
CQI110688003 110726682
NNU104589429
MING122071327
TSS122650120
PSOM113339774 113340075
NCOL116257475
OSA4331854
DOSAOs03t0184000-00(Os03g0184000)
OBR102713335
BDI100830664(PDS)
ATS109735159
TDC119284513 119291676
TAES100037655 123084692 123098691
TUA125538842
SBI110436156
ZMA542329
SITA101771481
SVS117835062
PVIR120647077 120689688
PHAI112878203
PDA103705191
EGU105056650
MUS103973843(PDS)
DCT110108194
PEQ110028688
AOF109848301
ATR18427456
SMOSELMODRAFT_232430 SELMODRAFT_269459
PPP112274368
CRECHLRE_12g509650v5
VCNVOLCADRAFT_88495
MNGMNEG_8557
CVRCHLNCDRAFT_34420
APROF751_0480
OLUOSTLU_38345 OSTLU_47627(AOX5)
OTAOT_ostta10g02860 OT_ostta16g00590
BPGBathy11g01800 Bathy11g03090
MISMICPUN_104873(PDS1) MICPUN_96647(PDS2)
MPPMICPUCDRAFT_12341 MICPUCDRAFT_49039(PSD2)
CMECYME_CMK151C
CCPCHC_T00009492001
SMINv1.2.025723.t1(symbB.v1.2.025723.t1)
PTIPHATRDRAFT_45735(PDS1) PHATRDRAFT_55102(PDS2)
FCYFRACYDRAFT_260963(PDH2) FRACYDRAFT_274501
TPSTHAPSDRAFT_1383(PDS1) THAPSDRAFT_23291
AAFAURANDRAFT_10705 AURANDRAFT_70771
EHXEMIHUDRAFT_430592 EMIHUDRAFT_74977
GTTGUITHDRAFT_85858
SVASVA_2656
DALDalk_4051
BCOBcell_1764
BCOHBC6307_11215
ASEDIRT44_12190
CTHUHUR95_10720
BBEVBBEV_1351
BSEBsel_2224
ESIExig_2022
BBEBBR47_19760
BFMBP422_05030
BAGRBA6348_19170
BCHSJNE38_10480
BCOPJD108_14595
PMSKNP414_07417
PMQPM3016_6970
PMWB2K_35005
PBVAR543_01825
ANXACH33_03330
ASOCCB4_00988(pds)
ATHEK3F53_15590
SACAFFV09_09570
TUMCBW65_17675
SYNslr1254(pds)
SYZMYO_112820(pds)
SYYSYNGTS_1271(pds)
SYTSYNGTI_1271(pds)
SYSSYNPCCN_1270(pds)
SYQSYNPCCP_1270(pds)
SYJD082_22590(pds)
SYOC7I86_06580(pds)
SYCsyc2113_c(pds)
SYUM744_06505
SYFSynpcc7942_1983
SYDSyncc9605_2395
SYESyncc9902_0298
SYGsync_2608
SYRSynRCC307_0238(crtD)
SYXSynWH7803_2273(crtD)
SYPSYNPCC7002_A1935(crtP)
CYACYA_0316(pds)
CYBCYB_1694(pds)
SYNESyn6312_1665
SYNPSyn7502_02248
SYNKKR100_14820
SYNRKR49_07565
SYNDKR52_04115
SYHSyncc8109_2504(crtD)
SYNWSynWH8103_02594(pds)
SYVAWQ23_09720
SYLAWQ21_08905
SYNCCB0101_14680(pds)
SYNYBM449_04420
DSLDacsa_1459
SYWSYNW2257(crtD)
CGCCyagr_2890
CYICBM981_3153(pds)
PMAPro_0167(pds)
PMMPMM0144(pds)
PMTPMT_2004
PMNPMN2A_1510
PMIPMT9312_0146
PMBA9601_01611(pds)
PMCP9515_01721(pds)
PMFP9303_26651(pds)
PMGP9301_01631(pds)
PMHP9215_01611(pds)
PMJP9211_01591(pds)
PMENATL1_02161(pds)
PRCEW14_0186
PRMEW15_0231
CMPCha6605_4759
AMRAM1_4826(crtP)
WNAKA717_26965(pds)
TVNNIES2134_114780(pds)
SLWBRW62_02990
TELtll1561(pds)
THNNK55_04445(crtP)
THECFFX45_10010(pds)
LEPLepto7376_2525
LENLEP3755_22460
LETO77CONTIG1_00579(pds_1)
LBOLBWT_53250
KOVK9N68_01195(pds)
LSCKIK02_13675(pds)
LSKJ5X98_03400(pds)
HHGXM38_038830
PSEUPse7367_2695
PSERABRG53_3627(pds)
THEUHPC62_14805(pds)
GENGM3709_531
GEEGM3708_3217
CHONNIES4102_28500
MARMAE_12930(pds)
MIQB5D77_13835
MVZmyaer102_47020(pds)
CANCyan10605_0874
CSNCyast_1865
CYLAA637_04015(crtP)
HAOPCC7418_3680
ENNFRE64_16100(pds)
CYUUCYN_01070
CYTcce_3754
CWACwatDRAFT_0947
CYPPCC8801_0308
CYHCyan8802_0308
CYCPCC7424_1157
CYJCyan7822_1223
CYNCyan7425_4188
TERTery_4011
ARPNIES39_C00940(crtP)
PAGHNIES204_23570(crtP)
PPSUNO713_04487(pds)
OXYHCG48_09995(pds)
MVAGD0A34_24655(pds)
LFSHFV01_12450(pds)
MICMic7113_2705
GEIGEI7407_1139
OACOscil6304_1226
ONIOsc7112_5867
MPROBJP34_19440
PHORJWS08_02695(pds)
PYHNEA10_09175(pds)
CEPCri9333_2890
ANAalr1832(pds)
NPUNpun_R2772
NOSNos7107_4144
NOPNos7524_4713
NONNOS3756_19130(pds)
NFLCOO91_04679
NOECLI64_05545(pds)
NSHGXM_04860
NEDHUN01_16250(pds)
AVAAva_4795
NAZAazo_2875
ANBANA_C20304(crtP)
ACYAnacy_3875
AWAAA650_04095
ANNEH233_12195(pds)
CSGCylst_3130
RSINB6N60_01723
CALOCal7507_3633
CALTCal6303_5614
CALHIJ00_15390
CALNNIES2098_62970
RIVRiv7116_4191
FISFIS3754_40470
NSPHBDGGKGIB_01293(pds_1)
DOUBMF77_02865(pds_2)
DFSHGD76_21915(pds)
DHTNG743_16720(pds)
CCURIAR63_05380(pds)
CRKL3I90_06365(pds)
AFLOHEQ12_15805(pds)
TOQHCG51_26170(pds)
NCNBZZ01_24125
CTHEChro_0494
PLPPle7327_0167
SCSSta7437_3291
STANSTA3757_36360
CEOETSB_0715
CERRGRSB_0674
CAUCaur_2352
CHLChy400_2535
CAGCagg_3041
OTEOter_4135
CTMCabther_A0039 Cabther_A0268 Cabther_A2116
CVLJ8C06_00190 J8C06_08910 J8C06_10845
CHLOJ8C02_00185 J8C02_01310 J8C02_10400
CTECT0807
CPCCpar_0836
CLZBIU88_07080
CCHCag_1188
CPHCpha266_1173
CPBCphamn1_1181
CLIClim_0877
PVICvib_1032
PLTPlut_1283
PPHPpha_1176
PAAPaes_0884
PROCPtc2401_00978(pds_2)
PROSCHL67_06780
CTSCtha_1159
NIWNisw_08580
NCTNMSP_0950
 » show all
Reference
1  [PMID:11714315]
  Authors
Breitenbach J, Zhu C, Sandmann G
  Title
Bleaching herbicide norflurazon inhibits phytoene desaturase by competition with  the cofactors.
  Journal
J Agric Food Chem 49:5270-2 (2001)
DOI:10.1021/jf0106751
Reference
2  [PMID:9226712]
  Authors
Schneider C, Boger P, Sandmann G
  Title
Phytoene desaturase: heterologous expression in an active state, purification, and biochemical properties.
  Journal
Protein Expr Purif 10:175-9 (1997)
DOI:10.1006/prep.1997.0730
  Sequence
Reference
3  [PMID:8489496]
  Authors
Fraser PD, Linden H, Sandmann G
  Title
Purification and reactivation of recombinant Synechococcus phytoene desaturase from an overexpressing strain of Escherichia coli.
  Journal
Biochem J 291 ( Pt 3):687-92 (1993)
DOI:10.1042/bj2910687
Reference
4  [PMID:15503129]
  Authors
Breitenbach J, Sandmann G
  Title
zeta-Carotene cis isomers as products and substrates in the plant poly-cis carotenoid biosynthetic pathway to lycopene.
  Journal
Planta 220:785-93 (2005)
DOI:10.1007/s00425-004-1395-2
  Sequence
[cann:107861625]
Other DBs
ExplorEnz - The Enzyme Database: 1.3.5.5
IUBMB Enzyme Nomenclature: 1.3.5.5
ExPASy - ENZYME nomenclature database: 1.3.5.5
BRENDA, the Enzyme Database: 1.3.5.5

DBGET integrated database retrieval system