KEGG   ENZYME: 1.3.98.5
Entry
EC 1.3.98.5                 Enzyme                                 
Name
hydrogen peroxide-dependent heme synthase;
coproheme III oxidative decarboxylase;
hemQ (gene name)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With other, known, physiological acceptors
Sysname
Fe-coproporphyrin III:hydrogen peroxide oxidoreductase (decarboxylating)
Reaction(IUBMB)
Fe-coproporphyrin III + 2 H2O2 = protoheme + 2 CO2 + 4 H2O (overall reaction) [RN:R11522];
(1a) Fe-coproporphyrin III + H2O2 = harderoheme III + CO2 + 2 H2O [RN:R12454];
(1b) harderoheme III + H2O2 = protoheme + CO2 + 2 H2O [RN:R12455]
Reaction(KEGG)
Substrate
Fe-coproporphyrin III [CPD:C21284];
H2O2 [CPD:C00027];
harderoheme III [CPD:C22173]
Product
protoheme [CPD:C00032];
CO2 [CPD:C00011];
H2O [CPD:C00001];
harderoheme III [CPD:C22173]
Comment
The enzyme participates in a heme biosynthesis pathway found in Gram-positive bacteria. The initial decarboxylation step is fast and yields the three-propanoate harderoheme isomer III. The second decarboxylation is much slower. cf. EC 1.3.98.6, SAM-dependent heme synthase.
History
EC 1.3.98.5 created 2019
Pathway
ec00860  Porphyrin metabolism
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K00435  hydrogen peroxide-dependent heme synthase
K25033  hydrogen peroxide-dependent heme synthase
Genes
DMMdnm_014420
SDOSD1155_05710
BSUBSU37670(ywfI)
BSRI33_3915
BSLA7A1_0186
BSHBSU6051_37670(ywfI)
BSYI653_18480
BSUTBSUB_04003(hemQ)
BSULBSUA_04003(hemQ)
BSUSQ433_20750
BSOBSNT_10425(ywfI)
BSNBSn5_09825
BSQB657_37670(hemQ)
BSXC663_3672(ywfI)
BSPU712_18985
BSSBSUW23_18605(ywfI)
BSTGYO_4153
BLIBL03956(ywfI)
BLDBLi03998(ywfI)
BLHBaLi_c40120(ywfI)
BAYRBAM_034860
BAQBACAU_3515(ywfI)
BYABANAU_3668(ywfI)
BAMPB938_17890
BQYMUS_4145(ywfI)
BAMLBAM5036_3416(hemQ)
BAMARBAU_3624(hemQ)
BAMNBASU_3400(hemQ)
BAMBBAPNAU_3682(ywfI)
BAMTAJ82_19675
BAMYV529_37580(ywfI)
BMPNG74_03661
BAOBAMF_3599(ywfI)
BAZBAMTA208_19065(ywfI)
BQLLL3_03911(ywfI)
BXHBAXH7_03903(ywfI)
BAMIKSO_001630
BAMCU471_36310
BAMFU722_18625
BSIACWD84_01695
BAEBATR1942_16800
BVMB9C48_17840
BSONS101395_00387
BHTDIC78_12140
BMOJHC660_36750(hemQ)
BTEQG4P54_19425
BIQAN935_19080
BANBA_5637
BARGBAA_5637
BATBAS5239
BAHBAMEG_5682
BAIBAA_5664
BAXH9401_5379
BANTA16_56490
BANRA16R_57170
BANSBAPAT_5404
BANHHYU01_27515
BANVDJ46_4284
BCEBC5388
BCABCE_5517
BCZBCE33L5086
BCRBCAH187_A5567
BCBBCB4264_A5511
BCUBCAH820_5483
BCGBCG9842_B5440
BCQBCQ_5229
BCXBCA_5540
BALBACI_c53830
BNCBCN_5316
BCFbcf_27060
BCERBCK_08415
BCYBcer98_3909
BTKBT9727_5069
BTLBALH_4887
BTBBMB171_C4983
BTTHD73_5801
BTHRYBT1520_28740
BTHIBTK_28590
BTCCT43_CH5428
BTFYBT020_26870
BTMMC28_4621
BTGBTB_c55880
BTIBTG_21445
BTNBTF1_25425
BTHTH175_ch5519
BTHUYBT1518_30300
BTWBF38_1111
BTHYAQ980_02350
BWEBcerKBAB4_5181
BWWbwei_4395
BMYOBG05_621
BTYBtoyo_2584
BMYCDJ92_2476
BBYCY96_26065
BWDCT694_28950
BTROFJR70_21085
BMOBMLA2C4_27920
BNTGSN03_25810
BPACLMD38_26910
BPANNLJ82_26580
BPUBPUM_3416
BPUMBW16_18140
BPUSUP12_17585
BIFN288_24050
BMETBMMGA3_16270
BSMBSM4216_3736
BGYBGLY_4402
BWHA9C19_00345
BXIBK049_09805
BALTCFN77_18045
BSAFBSL056_18685
BITBIS30_08550
BFDNCTC4823_00391
BDAFSZ17_22240
BSHILGQ02_20260
BBADK7T73_19010
BCABEFK13_19395
BRYM0696_19145
BJSMY9_3858
BACIB1NLA3E_21765
GSTHW35_09400
BACWQR42_17140
BACPSB24_11265
BACBOY17_01095
BACOOXB_1378
BACYQF06_17275
BACLBS34A_40850(ywfI)
BALMBsLM_3797
BACSAUL54_12265
BACQDOE78_23975
BACAFAY30_25240
BAQUK6959_15445
BCOBcell_4134
BHKB4U37_20670
BCOHBC6307_22325
BCIRC2I06_17085
BMQBMQ_5203
BMDBMD_5189
BMHBMWSH_0076
BMEGBG04_2197
BEOBEH_23695
BFXBC359_01695 BC359_07410
PKSIE339_23015
BCKBCO26_2853
BAGBcoa_1405
BCOABF29_2111
BHABH3825
BCLABC3912
BLEBleG1_3772
BKWBkAM31D_24750
BGIBGM20_13095
BPFBpOF4_07220(ywfI)
BONA361_26270
BKOCKF48_11985
CGOTJ1899_21190
CSUAIM538_22885
CFIRNAF01_24135
CSOALIS82_25520
OIHOB3023
OCNCUC15_17735
OCBCV093_19180
GKAGK3416
GTEGTCCBUS3UF5_38380
GTKGT3570_16780
GTMGT3921_01885
GLIGLN3_09805
BCALCWI35_10940
GTNGTNG_3362
GWCGWCH70_3365
GYCGYMC61_3473
GYAGYMC52_3505
GCTGC56T3_3401
GMCGY4MC1_3758
GGHGHH_c35120(ywfI)
GJFM493_17870
GEAGARCT_03400
GELIB49_09650
GSEGT50_08830
GSRGS3922_16185
GEJA0V43_14760
GZAIC807_13110
GTHGeoth_3863
PTLAOT13_03485
PTBDER53_04330
PCALBV455_01880
PARGPspKH34_37280
AFLAflv_2762
AGNAFK25_14125
ANMGFC28_2763
AAMYGFC30_304
ANLGFC29_2671
ANDGRQ40_17890
ACAIISX45_15190
ASEDIRT44_01670
LSPBsph_0946
LGYT479_02470
LFUHR49_21280
LYSLBYS11_02565
LYBC3943_03210
LYZDCE79_02110
LYGC1N55_04030
LPAKGDS87_02615
LAGRFJQ98_03280
LMACI6G82_15865
LYCFH508_0002415
LCAPICJ70_21905
HHDHBHAL_4659
HMNHM131_03875
HLIHLI_14195
TAPGZ22_15085
TAIDKS242_14520
VIRX953_17545
VHLBME96_17035
VIGBKP57_08490
VILCFK37_07615
VNECFK40_02905
VPNA21D_00986
VIMGWK91_11855
VPTKBP50_20015
LAOAOX59_15485
FPNABE65_020435
FARABE41_019595
SJEAAV35_002085
APAKAP3564_04145
BSJUP17_24425
BMURABE28_023110
PBUTDTO10_11010
PASABAOM_4922(cld)
PPSRI6J18_15355
PFRIL8956_25890
AQTFN924_16900
BTHVCQJ30_18380
PSYHD0S48_09280
PSYOPB01_03105
PRDF7984_18285
GRCGI584_21150
RUEDT065_10725
SALEEPH95_11350
SCIBHUG20_18670
SCIAHUG15_22380
POFGS400_18450
NMKCHR53_27320
NTMBTDUT50_02195
NDTL1999_28780
MEKUHUW50_08350
MSEMGMB29_25875
MDGK8L98_24060
MLITKDJ21_006190
AIAAWH56_006585
BLENNCTC4824_03925
SEDDERJ70_17445
BVQFHE72_22665
RMFD5E69_21270
BVJI5776_20220
BOUI5818_24750
CTHUHUR95_16880
BBEVBBEV_0110
BSEBsel_3224
MCUIG8O30_12755
GAJMY490_21505
PSUAFLK61_40270
SLMSMM221_07210
MJOFOF60_23595
HYIK2M58_10890
STEAC0679_14535
SAUSA0544
SAVSAV0587
SAWSAHV_0585
SAHSaurJH1_0625
SAJSaurJH9_0610
SAMMW0542
SASSAS0546
SARSAR0593
SACSACOL0633
SAXUSA300HOU_0580
SAASAUSA300_0569
SAOSAOUHSC_00573
SAENWMN_0550
SADSAAV_0549
SUUM013TW_0575
SUVSAVC_02520
SUESAOV_0621c
SUJSAA6159_00540
SUKSAA6008_00594
SUCECTR2_540
SUTSAT0131_00649
SUQHMPREF0772_12601
SUZMS7_0576
SUDST398NM01_0661
SUXSAEMRSA15_05150
SUWSATW20_06560
SUGSAPIG0661
SUFSARLGA251_05220
SAUASAAG_01009
SAUERSAU_000539
SAUNSAKOR_00577
SAUSSA40_0528
SAUUSA957_0543
SAUGSA268_0541
SAUZSAZ172_0589
SAUTSAI1T1_2004510
SAUJSAI2T2_1004530
SAUKSAI3T3_1004520
SAUQSAI4T8_1004510
SAUVSAI7S6_1004520
SAUWSAI5S5_1004480
SAUXSAI6T6_1004490
SAUYSAI8T7_1004520
SAUFX998_0628
SABSAB0537c
SUYSA2981_0564
SAUBC248_0662
SAUMBN843_5800
SAUCCA347_602
SAURSABB_00636
SAUIAZ30_02965
SAUDCH52_02825
SAMSNI36_02925
SUHSAMSHR1132_05310
SERSERP0235
SEPSE_0358
SEPPSEB_00280
SEPSDP17_1665
SHASH2405
SHHShL2_02200
SSPSSP2125
SCASCA_0241
SLGSLGD_02298
SLNSLUG_22140
SSDSPSINT_0283
SDTSPSE_2174
SDPNCTC12225_02393
SWAA284_10370
SPASSTP1_1673
SXYBE24_00725
SXLSXYLSMQ121_2109
SXOSXYL_02261
SHUSHYC_10700
SCAPAYP1020_2337
SSCHLH95_10290
SSCZRN70_11025
SAGQEP23_11460
SEQOSE1039_04160
SSIFAL483_08620
SCVA4G25_06475
SPETCEP67_09940
SLZB5P37_07385
SCOHBZ166_02600
SNLBJD96_11945
SKLC7J89_12510
SFQC7J90_01725
SHOMEGX58_03260
SMUSC7J88_08460
SCARDWB96_11595
SCHRDWB92_10855
SARLSAP2_21780
SPICSAMEA4384060_2281
SSHNCTC13712_00539
SSIMSAMEA4384339_0535
SDBCNQ82_12765
SLLOISP08_10775
SAULI6G39_01990
SSACI6I31_05710
SRAILN051_09970
SPSDJMB28_11470
STASHYI43_10805
SSCUCEP64_11385
SFFFOB90_09175
SSTESAMEA4384403_2280
MLENH3V22_10430
MVTI6J10_12110
MCLMCCL_1834
MCAKMCCS_23810
MACRBHM04_11555
MBOEHT586_11525
MARYLAU42_10970
MBRUMGG13_10360
MEPIKFV12_12410
MEQUKFV11_10560
SHVAAT16_13205
SBACBVH56_01105
JEAJEM45_08965
NAMPKPF49_07160
LMOlmo2113
LMNLM5578_2316
LMYLM5923_2267
LMTLMRG_01267
LMOCLMOSLCC5850_2178
LMOEBN418_2544
LMOBBN419_2550
LMODLMON_2187
LMOWAX10_04825
LMOQLM6179_2888(hemQ)
LMRLMR479A_2224(hemQ)
LMOMIJ09_14370
LMFLMOf2365_2146
LMCLm4b_02135
LMOGBN389_21440
LMPMUO_10840
LMOLLMOL312_2129
LMOJLM220_14566
LMOZLM1816_07648
LMOXAX24_08430
LMHLMHCC_0433
LMQLMM7_2215
LMLlmo4a_2174
LMGLMKG_00204
LMSLMLG_0313
LMJLMOG_01106
LMWLMOSLCC2755_2177
LMXLMOSLCC2372_2181
LMZLMOSLCC2482_2175
LMONLMOSLCC2376_2070
LMOSLMOSLCC7179_2089
LMOOLMOSLCC2378_2141
LMOYLMOSLCC2479_2178
LMOTLMOSLCC2540_2210
LMOALMOATCC19117_2135
LMOKCQ02_10950
LMVY193_04955
LINlin2218
LWElwe2132
LSGlse_2102
LIVLIV_2104
LIIJL52_11045
LIWAX25_11225
LIAJL58_11220
LIOJL53_11720
LWIUE46_04385
LGZNCTC10812_02027
LMARLAX80_010355
BTHSCNY62_03870
ESIExig_0217
EATEAT1b_1445
EANEab7_0205
EXMU719_01100
EXUESP131_03530
EAPKB235_03320
EACEKKI46_01355
EAURNMQ00_01750
BBEBBR47_45550
BLRBRLA_c040460
BFMBP422_18425
BAGRBA6348_08735
BRWGOP56_12860
BCHSJNE38_23750
BCOPJD108_05545
PJDPjdr2_4832
GYMGYMC10_5450
PPYPPE_03879
PPMPPSC2_20370(ywfI)
PPOPPM_4082(ywfI)
PPOLX809_36505
PPQPPSQR21_041190(ywfI)
PPOYRE92_16820
PMSKNP414_03744
PMQPM3016_1139
PMWB2K_05800
PTAHPL003_01340 HPL003_02245
PLVERIC2_c29580
PSABPSAB_19360
PDUPDUR_21990
PBDPBOR_30050
PGMPGRAT_26950
PODPODO_25700
PAENP40081_31545
PAEFR50345_25635
PAEQR50912_28380
PSTEPSTEL_22005
PAEAR70723_27190
PAEER70331_26270
PAEHH70357_29035
PAEJH70737_25440
PBJVN24_16000
PIHUB51_01730
PRIPRIO_5637
PSONJI735_03165
PPEOABE82_20420
PNPIJ22_30930
POWIJ21_13710
PBVAR543_20595
PXLBS614_28260
PYGAWM70_14315
PSWUSY83_00030
PDHB9T62_26180
PIBBBD41_18905
PCXLPB68_07015
PKBB4V02_04940
PAIHASL14_17495
PVOPVOR_29444
PLWD5F53_02820
PLENEIM92_08855
PPSCEHS13_08605
PLUTEI981_23705
PALBEJC50_10970
PCHIPC41400_25470
PBKBack11_29950
PPRTET464_19480
PBACHUB98_11725
PRZGZH47_07600
PLYCGXP70_08790
PSOPKP014_26040
PTRIKDC22_27480
PALOE6C60_3442
PCELHUB94_21425
PTJJRJ22_24230
PALRHGI30_17830
TCOTheco_2742
ANXACH33_04545
ASOCCB4_01234
ATHEK3F53_14360
COHEAV92_01500
COHNKCTCHS21_44860
CCHLFPL14_06415
CHEBHH215_13725
SACAFFV09_06435
AACAaci_1765
AADTC41_1664
AFXJZ786_08640
AACOK1I37_12165
ACURJZ785_12450 JZ785_16020
BTSBtus_1292
KYRCVV65_09790
TUMCBW65_11530
TABCIG75_16735
EFFskT53_18740
SIVSSIL_3430
SSILSOLI23_01285
SOBCSE16_02175
PLNPlano_2453
PKUAUO94_03355
PRTAUC31_13850
PLLI858_010520
PANABBH88_06660
PDGBCM40_02930
PHCBBI08_09510
PMARB0X71_15305
PPLABBI15_08460
PFAEAJGP001_14195
PLXCW734_14515
PMATBBI11_14085
PDECH1Q58_13390
PGQFK545_03485
JEOJMA_31060
KURASO14_2586
KZONCTC404_00525
SPSYAZE41_19750
SPORSporoP33_11210
SPOPSporoP37_11625
SURESporoP32a_11905
SPOSDV702_15870
SPAEE2C16_11800
SPOOJ3U78_18415
RSTATY39_16575
PAEKD3873_02415
PANCE2636_13785
PLAYDNR44_007425
VIJJNUCC6_17325
NTRB0W44_13830
TVUAB849_010865
PABSJIR001_25190(ywfI)
LLDP620_14720
LCTBI355_0138
CMICcaldi_00530(ywfI)
TMRTmar_0490
THEPDYI95_002200
SAYTPY_1863
SAPSulac_2065
STHRBXT84_12060
VPRVpar_0219
VATB7L28_08440
VRM44547418_00240
VDNNCTC11831_00206
VNKVEIT17_02090
LPILLIP_0706
MTURv2676c
MTVRVBD_2676c
MTCMT2750
MRAMRA_2704
MTFTBFG_12691
MTBTBMG_01297
MTKTBSG_01308
MTZTBXG_001288
MTGMRGA327_16430
MTIMRGA423_16640
MTECCDC5079_2459
MTURCFBS_2828
MTLCCDC5180_2429
MTOMTCTRI2_2728
MTDUDA_2676c
MTNERDMAN_2938
MTJJ112_14340
MTUBMT7199_2708
MTUCJ113_18615
MTUEJ114_14285
MTXM943_13840
MTUHI917_18795
MTULTBHG_02612
MTUTHKBT1_2819
MTUUHKBT2_2822
MTQHKBS1_2826
MBOBQ2027_MB2695C
MBBBCG_2689c
MBTJTY_2683
MBMBCGMEX_2682c
MBKK60_027680
MBXBCGT_2508
MAFMAF_26800
MMICRN08_2960
MCEMCAN_27021
MCQBN44_60127
MCVBN43_40348
MCXBN42_40650
MCZBN45_51055
MLEML1045
MLBMLBr01045
MPAMAP_2797c
MAOMAP4_1015
MAVIRC58_04995
MAVURE97_04990
MAVMAV_3571
MITOCO_34020
MIAOCU_34040
MIDMIP_05124
MYOOEM_34400
MCHIAN480_18025
MIROCQ_35240
MMALCKJ54_15900
MLPMLM_1546
MMANMMAN_03970
MSAMycsm_02634
MULMUL_3310
MMIMMAR_2040
MMAEMMARE11_19640
MLIMULP_02214
MPSEMPSD_20660
MSHOMSHO_51430
MMCMmcs_2214
MKMMkms_2260
MJLMjls_2203
MMMW7S_17015
MKNMKAN_25530
MYVG155_13100
MYEAB431_12020
MGOAFA91_25575
MHADB586_14395
MDXBTO20_21220
MSHGMSG_01852
MFJMFLOJ_13970
MSTOMSTO_15470
MSIMMSIM_04770
MSAKMSAS_56540
MKUI2456_10030
MGROFZ046_17265
MXEMYXE_30920
MNVMNVI_34610
MPAGC0J29_11625
MNMMNVM_36260
MGORH0P51_11195
MCOOMCOO_02760
MBAIMB901379_01861
MSEOMSEO_06530
MHEKJMUB5695_03080
MGAUMGALJ_09480
MLJMLAC_26090
MBRDMBRA_44960
MSHJMSHI_20320
MKRMKOR_14950
MDFK0O62_12520
MMAMK3U93_09055
MHOLK3U96_15390
MHERK3U94_13735
MSENK3U95_10600
MPAEK0O64_11690
MSPGF6B93_08310
MOTLTS72_14525
MLMMLPF_2054(cld)
MVMMJO54_13880
MRFMJO55_11190
MPAAMKK62_15015
MCROMI149_12555
MSMMSMEG_2782
MSGMSMEI_2713
MSBLJ00_13830
MSNLI99_13835
MSHLI98_13840
MVAMvan_2483
MGIMflv_3917
MSPMspyr1_32620
MCBMycch_2182
MNED174_12190
MYNMyAD_11970
MFTXA26_26930
MPHLMPHLCCUG_03080(cld)
MVQMYVA_2376
MLLB1R94_17090
MRHMycrhN_5538
MTHN4412656_02702
MHASMHAS_02314
MDUMDUV_20870
MCHTMCHIJ_43470
MDRMDOR_15650
MAUUNCTC10437_02324
MMAGMMAD_23790
MMORMMOR_39750
MFXMFAL_04880
MAICMAIC_20970
MIJMINS_22850
MALVMALV_12230
MTYMTOK_42160
MPSCMPSYJ_41970
MARZMARA_15890
MGADMGAD_14450
MHEVMHEL_45930
MSARMSAR_33870
MANYMANY_07440
MAUBMAUB_57020
MPOFMPOR_27960
MPHUMPHO_11860
MMUCC1S78_012330
MMATMMAGJ_58360
MBOKMBOE_47940
MFGK6L26_19130
MSEIMSEDJ_36090
MFLVNCTC10271_03055
MCEEMCEL_12970
MBRML2Z93_002289
MABMAB_2984c
MMVMYCMA_1646
MABBMASS_2919
MABLMMASJCM_2983
MCHEBB28_14995
MIZBAB75_16045
MSTEMSTE_02949
MSAOMYCSP_13470
MSALDSM43276_02764
MJDJDM601_2422
MTER4434518_02354
MMINMMIN_01280
MHIBMHIB_18720
ASDAS9A_1782
MPAKMIU77_11580
CGLCgl1899(Cgl1899)
CGBcg2079
CGUWA5_1824
CGTcgR_1728
CGSC624_09170
CGGC629_09180
CGMcgp_2079
CGJAR0_08935
CGQCGLAR1_08785
CGXSB89_08625
CEFCE1792
CDIDIP1394
CDPCD241_1339
CDHCDB402_1305
CDTCDHC01_1338
CDECDHC02_1295
CDRCDHC03_1316
CDACDHC04_1316
CDZCD31A_1411
CDBCDBH8_1388
CDSCDC7B_1398
CDDCDCE8392_1312
CDWCDPW8_1384
CDVCDVA01_1279
CDIPERS451417_01417
CJKjk1073
CURcu0042
CUACU7111_0041
CARcauri_1441
CKPckrop_1047
CPUCPFRC_06045
CPLCp3995_1222
CPGCP316_06205
CPPCpP54B96_1216
CPKCP1002_07100
CPQCPC231_06050
CPXCPI19_05470
CPZCpPAT10_1191
CORCp267_1250
COPCP31_06435
CODCp106_1175
COSCp4202_1185
COICPCIP5297_06220
COECP258_06220
COUCP162_05085
CPSECPTA_01771
CPSUCPTB_01992
CPSFCPTC_01762
CRDCRES_1489
CULCULC22_01306
CUCCULC809_01292
CUECULC0102_1421
CUNCul210932_1372
CUSCulFRC11_1280
CUQCul210931_1264
CUZCul05146_1338
CUJCUL131002_1293c
CVACVAR_1566
CHNA605_08185
CCNH924_07940
CTERA606_06215
CMDB841_07510
CAZCARG_05525
CFNCFAL_06015
CCGCCASEI_06660
CVTB843_07850
CGYCGLY_08075
CAXCATYP_04545
CIICIMIT_07120
CUVCUREI_06920
COADR71_2112
CDOCDOO_08310
CHMB842_07515
CSXCSING_07885
CMQB840_07155
CKUUL82_05975
CCJUL81_06770
CMVCMUST_08885
CEICEPID_07225
CTEDCTEST_07585
CUTCUTER_06325
CLWCLAC_05755
CDXCDES_08480
CSPWM42_2538
CSTACSTAT_05955
CCJZccrud_08175
CFKCFRA_04985
CPHOCPHO_05320
CFCCFLV_07095
CGVCGLAU_07155
CSTRCBE89_06360
CAQUCAQU_07200
CSPHCSPHI_05955
CAMGCAMM_06150
CMINNCTC10288_01060
CPEGCPELA_04840
CXEFOB82_11610
CEECENDO_06480
CSANE3227_08620
CGKCGERO_06330
CRFFRC0190_01430
CRLNCTC7448_02051
CCHOCCHOA_06650
CPRECsp1_12840
CPSOCPPEL_05045
CSURN24_1968
CCYSSAMEA4530656_0950
CMATHBA49_01090
CYZC3B44_04890
CKFI6I12_05965
CANSGP473_04950
CLIAC3E79_06340
CPRPI6I69_00600
CAMCI6I65_01975
CGLUI6J20_02890
CUOCUROG_05490
CLIZG7Y31_06940
CSILCBE74_07045
CTUBI6I74_00245
CLUJIAU68_06645
CQNG7Y29_06180
CKWCKALI_06560
CCOECETAM_07570
COKCOCCU_08225
CZOIAU67_02505
CORYFQV43_05805
CMFGWO64_005320
CWKIA203_07260
CUWLH390_06520
CPOYGP475_06640
CACCCACC_07155(cld)
CFYI6L56_02060
BFVC628_09130
NFANFA_37360
NFRERS450000_00164
NCYNOCYR_3628
NBRO3I_029315
NNONONO_c52570
NSLBOX37_20285
NSRNS506_05836
NTPCRH09_24385
NOZDMB37_08190
NODFOH10_18550
NAHF5544_29305
NADNCTC11293_05101
NWLNWFMUON74_25430
NIEKV110_28430
NTCKHQ06_30370
NHUH0264_29320
NYALTV02_04690
NGPLTT66_24840
RHARHA1_ro06860
RERRER_28490
REYO5Y_13125
REBXU06_13345
RQIC1M55_14355
ROPROP_68450
ROAPd630_LPD03485
RPYY013_01955
RBYCEJ39_12650
RHBNY08_1199
RAVAAT18_12340
RFAA3L23_04444(cld)
RHSA3Q41_03823(cld)
RHWBFN03_06615
RRZCS378_02110
RHUA3Q40_01541
RHQIM25_15940
RHODAOT96_24565
RRT4535765_02093
RCRNCTC10994_00771
RTMG4H71_20495
RKOJWS14_36970
RGOKYT97_01800
ROZCBI38_17015
RPSKJWS13_07225
REQREQ_20610
GBRGbro_2265
GPOGPOL_c21600
GORKTR9_2182
GOQACH46_09410
GTABCM27_11675
GOCCXX93_13445
GITC6V83_09840
GRUGCWB2_14010
GOMD7316_00786
GAVC5O27_14080
GODGKZ92_12880
GAMGII34_10535
GPDGII33_10090
GJIH1R19_10875
GOILK459_22570
GHNMVF96_11065
GAMIIHQ52_16615
GMGNWF22_21390
SPINKV203_07855
TPRTpau_1894
TSMASU32_10165
TPULTPB0596_26990
SRTSrot_1917
DTMBJL86_1777
DITC3V38_14540
DIZCT688_08695
DPCA6048_08930
DLUA6035_08485
DKNNHB83_08295
TOYFO059_09945
SCOSCO6042(SC1B5.02)
SALBXNR_0758
SMASAVERM_2221
SGRSGR_1469
SGBWQO_27895
SCBSCAB_20801
SSXSACTE_5263
SVLStrvi_2308
SHYSHJG_7102
SHOSHJGH_6862
SRCM271_14275
SMALSMALA_5901
SSOII1A49_33345
SFASfla_1209
SBHSBI_03081
SVESVEN_5833
SDVBN159_2384
SALSSLNWT_0795
STRPF750_5626(hemQ)
SFISFUL_5998
SCIB446_28305
SALUDC74_6073
SALLSAZ_31330
SLVSLIV_07930
SGUSGLAU_25835
SVTSVTN_29210
STREGZL_02778
SCWTU94_25810
SLDT261_2027
SLCSL103_26115
SXISXIM_46570
STRMM444_26530
STRCAA958_27870
SAMBSAM23877_5756
SPRISPRI_1781
SCZABE83_06350
SCXAS200_12275
SRWTUE45_06648
STRFASR50_27480
SLEsle_16390(sle_16390)
SRNA4G23_04651
SPAVSpa2297_25415
STRTA8713_25135
SCLFBB341_04660
SGSAVL59_11730
STSIA4E84_30960
SKYD0C37_05150
SALWCP975_28050
SGMGCM10017557_18100
SCADDN051_10745
SPHWNFX46_09680
SLSSLINC_6446
SNRSNOUR_11900
SPLULK06_026525
STRDNI25_09165
SNWBBN63_06600
SAUOBV401_33410
SSIAA7J05_08840
SVUB1H20_28605
SPUNBFF78_10950
SGVB1H19_30550
SLAUSLA_5907
SALFSMD44_06640
SALJSMD11_1529
SLXSLAV_09885(cld)
STROSTRMOE7_29535
SFKKY5_6206
SNZDC008_27045
SGEDWG14_02079
SRJSRO_1767
SLKSLUN_30695
SDXC4B68_09315
SGDELQ87_09020
SQZFQU76_27020
SCYAEJ357_35725
SASTCD934_06370
SNQCP978_03140 CP978_26100
STIRDDW44_24475
SKACP970_10005
SGZC0216_08985
SVNCP980_07625
SNKCP967_05800
SHAWCEB94_31560
SRKFGW37_25435
SFICEIZ62_06650
SGALCP966_28160
SSPODDQ41_26115
SVRCP971_09595
SPADDVK44_28435
SFYGFH48_11135
SAQUEJC51_36025
SGFHEP81_01951
SCAVCVT27_27385
SSEOD0Z67_23020
SBYH7H31_06440
SRIMCP984_08630
SSUBCP968_08215
SPHVF9278_37685
SCINCP977_26635
SFUGCNQ36_25720
SPACB1H29_08530
STSUB7R87_27475
SCHACP983_10310
SGXH4W23_30295
SCOECP976_33310
SBATG4Z16_05875
SSPBCP982_31765
SNFJYK04_06426
SPLACP981_29685
SBROGQF42_32660
STUIGCM10017668_55250
SATAC5746_32340
SCHFIPT68_28335
SHUNDWB77_01841
SHARHUT13_23325
SCYGS1361_30205
SFEUIM697_33020
SLIAHA039_06960
SDWK7C20_28530
SVDCP969_29190
SCALI6J39_28455
SAUHSU9_027255
SFBCP974_24940
SMOBJ7W19_25030
SPRACP972_28165
SPEUCGZ69_28810
SROIIAG44_09015
SXNIAG42_08010
SGJIAG43_25995
SHKJ2N69_29340
SANUK7396_08535
STRYEQG64_28615
SDDD9753_07795
SACTDMT42_29685
SMAOCAG99_03565
SGOBtest1122_22240
SINEKI385_33990
SLFJEQ17_12570
SDECL3078_35215
SAOVG3H79_07715
SDURM4V62_11370
SYANNRK68_26735
SCTSCAT_4690
SCYSCATT_46820
KSKKSE_55140
KABB7C62_29790
KAUB6264_04675
KITCFP65_5401
STRIC7M71_023315
YIALO772_09425
STRHGXP74_31400
ABRYNYE86_25175
LXLKDY119_02678(hemH)
PSICJ4E96_04100
CCAFFGD68_05060
MLIQNMQ05_16305
LLUTK1X41_01060
HEHL3i23_00660
GSDM3M28_11650
ACITHPK19_17270
BCVBcav_1089
JDEJden_1885
KSEKsed_15650
DNIHX89_06575
DAYFV141_05930
DERMH7F30_11615
LMOIVV02_16225
YIMJ5M86_08510
ALXLVQ62_10930
XCEXcel_2623
XYLET495_09405
XYAET471_01920
IVAIsova_2452
IDOI598_3284
CETB8281_08605
CCEUCBR64_02675
SKESked_08350
CFLCfla_2406
CFICelf_1281
CGACelgi_1049
CEZCBP52_08225
CELZE5225_05605
CEJGC089_05865
CELHGXP71_09920
CIRALFM56_06030
CPALF1D97_14880
CELCK5O09_13515
CDONKKR89_12030
CWANKG103_12125
CFENKG102_12185
OEKFFI11_018330
ICAIntca_1906
ARSADJ73_11665
JTEASJ30_06975
JLIEXU32_07625
JMEEEW87_008165
JAYH7A72_07030
TEHGKE56_06030
PHWG7075_05785
PEIH9L10_06530
SERJSGUI_0519
SERWFY030_06365
ORNDV701_03580
ORZFNH13_09515
BLYA2T55_10420
BLINBLSMQ_2298
BRIFDF13_12370
BLUTEW640_02190
BCAUI6G59_13950
DCOSAMEA4475696_1613
AUSIPK37_18610
GEZFE251_06780
GYUFE374_17985
ARUBJ5A65_06590
MPHMLP_23160
MIKFOE78_12615
MICGGJV80_08825
TLATLA_TLA_02756
RAINRai3103_15170
NCANoca_3671
NDKI601_0385
NOYEXE57_07840
NOIFCL41_02985
NOOFE634_15565
NDPE2C04_03710
NSNEXE58_12160
NBEBack2_22300
NANOG5V58_01450
NMESH9L09_18510
NAROCFH99_06045
NPIG7071_01495
NAQUENKNEFLB_03811
NROK8W59_03295
NOQLN652_09150
NCQK6T13_03530
NPCKUV85_16995
NPSKRR39_06020
PSIMKR76_21680
AERAERYTH_10090
AEZC3E78_10635
AEBC6I20_09405
AEFGEV26_10515
MUZH4N58_08500
KFLKfla_3727
KQIF1D05_36995
TFUTfu_1896
THAONI17_011615
TALXFOF52_09130
NDANdas_2827
NALB005_5371
NGVCDO52_17910
NEXNE857_20355
STRREKD16_14575
SAIUJ4H86_00755
TCUTcur_1766
ACTWF7P10_05595
AGRAAGRA3207_001283
SROSros_6718
NOABKM31_01165
NOWGBF35_36875
NCXNocox_29950
NGNLCN96_41140
TBITbis_2261
GOBGobs_1891
BSDBLASA_3273
BLAPMVA48_01380
MMARMODMU_3905
KRAKrad_1587
SENSACE_1838
SACGFDZ84_21520
SVISvir_24070
SACCEYD13_13440(cld)
AMDAMED_2645
AMNRAM_13445
AMMAMES_2617
AMZB737_2618
AOIAORI_2632
AJAAJAP_25670
AMQAMETH_4743
AMYCCU254_11085
AMYBBKN51_05785
AABA4R43_13820
AMYYYIM_30985
AORISD37_14255
AACDLWP59_28630
APRTMUY14_23145
AROONQK81_08945
PDXPsed_2896
PSEAWY02_27715
PSEEFRP1_15030
PSEHXF36_15250
PSEQAD006_22695
PECQAD017_02280
PHHAFB00_00260
PAUTPdca_41780
PBROHOP40_29885
APRECNX65_07720
AMIAmir_1554
SESPBN6_18640
SSYIEKG83_09100
KALKALB_6806
KPHYAOZ06_14845
LEDBBK82_01020
AHMTL08_20570
ACTIUA75_24215
ACADUA74_23710
AHGAHOG_21590
ACTAC1701_04720
ALOCRK55877
PMADBAY61_11315
SACEGIY23_08220
ACTUActkin_01730
STPStrop_1534
SAQSare_1476
MAUMicau_1629
MILML5_1888
MICBMicB006_1653
MTUACSH63_16135
MICHFJK98_08505
MTEMGCE86_02335
MCABHXZ27_09420
MSAGGCM10017556_41740
VMAVAB18032_12740
MCRAID554_04015
ASEACPL_7084
AMSAMIS_68280
ACTNL083_6661
AFSAFR_35165
ACTSACWT_6953
AIHAiant_29010
ACTRAsp14428_64010
PLKCIK06_08330
PLABC6361_15040
PLATC6W10_15310
PFLAPflav_089020
PSUUPsuf_052070
VERHUT12_08990
ATLAthai_34420
ASERAsera_40340
PRYPrubr_42290
CATICS0771_25620
DVCDvina_09400
DFUDfulv_08830
DROSDrose_09015
DAURDaura_08820
NHYJQS43_07685
CCAZCOUCH_09135
CAICaci_6785
SNASnas_3926
NAVJQS30_05720
GLYK3N28_17435
TPECHLG82_09645
BASTBAST_0811
AEYCDG81_15750
JTLM6D93_10215
ABAIIMCC26256_11285
AFOAfer_1843
AYMYM304_04960
ATQGH723_15810
AQZKSP35_12025
IAMHC251_03885
ERZER308_00365
EUZDVS28_a2822
TTHTT_C1352(curD)
TTJTTHA1714(TTHA1714)
TTSThthe16_1731
TTLTtJL18_0330
TSCTSC_c02510
THCTCCBUS3UF1_20310
TOSTheos_0057
TAQTO73_0150
TPARAV541_02185
TBCA0O31_01283
TANTKNN15_05465
ROOG5S37_01735
LUOHHL09_18680
LAMBKBB96_11785
SOAG3M56_007800
XIIAMD24_00296
MINMinf_0914(ywfI)
MKCkam1_945
MEAPMTHMO_0945(ywfI)
RBARB10088
PSLPsta_0500
PIRVN12_21815
RULUC8_30990
RMLFF011L_28290
MFFMFFC18_36880
ROLCA51_16620
AHELQ31a_27770
LCREPla8534_34670
AAGGETAA8_34250 ETAA8_45640
BVOPan97_32450
RLCK227x_42170
TTFTHTE_3205
LPAVPLANPX_1976
AMUCPan181_18450
PNDPla175_33390
AMOBHG15A2_19530
PLMPlim_3790
PEHSpb1_03670
PBSPlabr_0183
PLSVT03_27570
PLHVT85_16120
FMRFuma_03866
GMRGmarT_28820
GIMF1728_00475
GPNPan110_27730
MRIMal4_10210
SDYNMal52_40160
PLONPla110_22950
IPAIsop_0903
SACISinac_2594
PBORBSF38_04551
AGVOJF2_61070
ABAAcid345_1955
ACAACP_0819
GRWFTO74_08745
GRBGOB94_15625
TALBFTW19_20935
ABASACPOL_2493
ADINH7849_07010
ORPMOP44_17845
SUSAcid_0345
PFERIRI77_25065
ABACLuPra_03258
GBAJ421_3680
HALVNG_2021C
HSLOE_3832F(hemQ)
HDLHALDL1_15020
HHBHhub_3323(hemQ)
HAGSJT689_09475
HABOJRZ79_07860
HNOLT974_13435
HLULT972_01345
HANRLJ422_08125
HJEHacjB3_04330
HALHHTSR_1774
HHSRHSR6_1840
HSUHLASF_1969
HSFHLASA_1955
SALRFQU85_06030
HALREFA46_002595
HAADMW046_04995
HALXM0R89_04325
HAXZM0R88_04385
SALIL593_03925
SAIMK0C01_07570 K0C01_11015
HARAAArcS_0406(ywfI)
HMArrnAC3100
HHIHAH_0351
HHNHISP_01840
HABSG26_09650
HTABVU17_01680
HALJG9465_01025
HSINKDQ40_11925
NPHNP_2262A(hemQ)
NMONmlp_1161(hemQ)
NHOHWV23_13550
NSALHWV07_07400
HUTHuta_1222
HTIHTIA_1138
HALAHrd1104_02920
HMUHmuk_1250
HALZE5139_09425
HALLLC1Hm_0437(ywfI)
HAZPGBQ70_09420
HALIBV210_11030
HSNDV733_01920
HDSHSR122_0255(ywfI)
HRRHZS55_05230
HPELHZS54_05335
HLTI7X12_08040
HARCHARCEL1_08860
HDOMUK72_00650
SSAIN0B31_10540
HWAHQ_1094A(hemQ)
HWCHqrw_1123(hemQ)
HVOHVO_1871(hemQ)
HMEHFX_1953
HGIABY42_09050
HALEG3A49_12355
HLSKU306_03270
HBOHbor_04740
HAQDU484_03585
HAJDU500_04070
HAERDU502_01740
HRAEI982_11655
HLMDV707_14565
HALMFCF25_01060
HLAHlac_2193
HALPDOS48_10455
HALBEKH57_14015
HEZZEO776_12365
HALQHrr1229_011170
HSSJ7656_03955
HSAIHPS36_09290
HAZZKI388_10905
HAEhalTADL_0324 halTADL_1349
HALNB4589_011930
HALGHUG10_10510
HALUHUG12_05360
HMPK6T50_07675
HREK6T36_07495
HRMK6T25_08300
HACBHbl1158_14060
HDFAArcSl_2750
HAHHalar_2702
HTUHtur_3475
HDABB347_15860
HSALJMJ58_10985
HLOJ0X27_05735
HAKZJ0X25_05090
NMGNmag_1506(hemQ)
HXAHalxa_3477
NATNJ7G_2646
NPENatpe_0437
NVRFEJ81_02450
NPLFGF80_09370
NAYHYG81_08510
HALYHYG82_11475
HJTDVR14_11480
NGENatgr_2412
HRUHalru_2776
NOUNatoc_2380
HLRHALLA_17850
HLCCHINAEXTREME07140
NAJB1756_10560
NAGAArcMg_0396
NANAArc1_0404
NBGDV706_05055
NASGCU68_08105
SAWLNGM29_00915
 » show all
Reference
1  [PMID:20543190]
  Authors
Dailey TA, Boynton TO, Albetel AN, Gerdes S, Johnson MK, Dailey HA
  Title
Discovery and Characterization of HemQ: an essential heme biosynthetic pathway component.
  Journal
J Biol Chem 285:25978-86 (2010)
DOI:10.1074/jbc.M110.142604
Reference
2  [PMID:26083961]
  Authors
Celis AI, Streit BR, Moraski GC, Kant R, Lash TD, Lukat-Rodgers GS, Rodgers KR, DuBois JL
  Title
Unusual Peroxide-Dependent, Heme-Transforming Reaction Catalyzed by HemQ.
  Journal
Biochemistry 54:4022-32 (2015)
DOI:10.1021/acs.biochem.5b00492
Reference
3  [PMID:27758026]
  Authors
Hofbauer S, Mlynek G, Milazzo L, Puhringer D, Maresch D, Schaffner I, Furtmuller PG, Smulevich G, Djinovic-Carugo K, Obinger C
  Title
Hydrogen peroxide-mediated conversion of coproheme to heme b by HemQ-lessons from the first crystal structure and kinetic studies.
  Journal
FEBS J 283:4386-4401 (2016)
DOI:10.1111/febs.13930
  Sequence
[lmo:lmo2113]
Reference
4  [PMID:27936663]
  Authors
Celis AI, Gauss GH, Streit BR, Shisler K, Moraski GC, Rodgers KR, Lukat-Rodgers GS, Peters JW, DuBois JL
  Title
Structure-Based Mechanism for Oxidative Decarboxylation Reactions Mediated by Amino Acids and Heme Propionates in Coproheme Decarboxylase (HemQ).
  Journal
J Am Chem Soc 139:1900-1911 (2017)
DOI:10.1021/jacs.6b11324
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.3.98.5
IUBMB Enzyme Nomenclature: 1.3.98.5
ExPASy - ENZYME nomenclature database: 1.3.98.5
BRENDA, the Enzyme Database: 1.3.98.5

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