KEGG   ENZYME: 1.4.1.16
Entry
EC 1.4.1.16                 Enzyme                                 
Name
diaminopimelate dehydrogenase;
meso-alpha,epsilon-diaminopimelate dehydrogenase;
meso-diaminopimelate dehydrogenase
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With NAD+ or NADP+ as acceptor
Sysname
meso-2,6-diaminoheptanedioate:NADP+ oxidoreductase (deaminating)
Reaction(IUBMB)
meso-2,6-diaminoheptanedioate + H2O + NADP+ = L-2-amino-6-oxoheptanedioate + NH3 + NADPH + H+ [RN:R02755]
Reaction(KEGG)
R02755
Substrate
meso-2,6-diaminoheptanedioate [CPD:C00680];
H2O [CPD:C00001];
NADP+ [CPD:C00006]
Product
L-2-amino-6-oxoheptanedioate [CPD:C03871];
NH3 [CPD:C00014];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.4.1.16 created 1981
Pathway
ec00300  Lysine biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K03340  diaminopimelate dehydrogenase
Genes
PMRPMI0150
PMIBBB2000_0314
PVLAOB99_03565
PVGCRN77_00455
PHAUPH4a_10775
PROTBTA34_02460
PCOLF1325_03720
PCIBF9282_03540
PPEEI6G31_05760
PSIS70_05250
PSXDR96_162
PSTABGK56_08125
PRGRB151_034360(ddh)
PALACO695_09150
PHEINCTC12003_01013(ddh)
PRQCYG50_21290
PRJNCTC6933_03031(ddh)
PVCG3341_04960
PMAGJI723_05310
MMKMU9_1099
MWIMNY66_12545
LPVHYN51_05185
PFQQQ39_04950
PRAGEKN56_13215
LRINCTC12151_02519(ddh)
PSJPSJM300_13000
ACXAchr_22250
PBBAKN87_06490
MBSMRBBS_3827(ddh)
PRWPsycPRwf_0683
PURAOC03_01195
PSYCDABAL43B_2080
PSYYDLE54_03600
AIDCTZ23_03480
ADVDJ533_05515
AWUBEN71_15855
ALWFOB21_15185
ACHICDG60_04335
ATGJ4G44_05200
RHHE0Z06_07400
TGRTgr7_1592
OCMCBP12_05260
OPFCBP31_13355
ORBIPMB12_10075
SINIGT972_08685
IGNMMG00_08780
GPBHDN1F_28820(ddh)
CCUPBKK81_33865
BTRMSAMEA390648702348(ddh)
BOJCBF45_10505
PUTPT7_3660
PUSCKA81_10010
CDNBN940_07121
AFAUZ73_15015
AFQAFA_14700
AAQUD3M96_15610
AAMMFE795_13565
PHNPAEH1_06230
OURCEQ07_10595
OUEI6G29_06435
KGYEHF36_10905
RFRRfer_1518
AJSAjs_2757
DACDaci_2479
DELDelCs14_4183
DTSBI380_11875
DHKBO996_11590
DLAI6G47_11815
CTTCtCNB1_3320
CTESO987_19680
CKEB5M06_11060
COFFOZ74_12680
ADNAlide_1487
ADKAlide2_3439
OTDJ1M35_03835
DPYBA022_02455
DIADtpsy_2247
SIMPC6571_15485
MELMC7H73_10800
MELAC6568_01905
MJELVC68_06495
HARHEAR2481(ddh)
OFOBRW83_0212(ddh)
NIINit79A3_2698
NCOAAW31_00705
THUAC731_001535
DDZDSYM_25360
CCOCCC13826_1251(ddh)
CGRACGRAC_1064(ddh)
CSPFCSF_0917(ddh)
CRXCRECT_1233(ddh)
CCORCCORG_1485(ddh)
CSHOCSHOW_0916(ddh)
ASKEI285_05620
ATPATR_1025(ddh)
ACIBACBT_1441(ddh)
ACREACRYA_1021(ddh)
ALANALANTH_1244(ddh)
APOCAPORC_0931(ddh)
AFCAFAEC_1025(ddh)
ATHRATH_1023(ddh)
PCAPcar_2787
PEFA7E78_06410
DDSDdes_1119
DPGDESPIGER_1507
DEFCNY67_07015
VINAKJ08_2232
BSEDDN745_12495
BFDNCTC4823_02682(ddh)
BDAFSZ17_06460
BACOOXB_3226
BAQUK6959_15875
CSOALIS82_05355
OCNCUC15_05150
OCBCV093_05415
AXLAXY_06490(ddh)
LSPBsph_3035
LGYT479_10490
LFUHR49_11360
LYSLBYS11_11950
LYBC3943_16180
LYZDCE79_09235
LPAKGDS87_12910
LAGRFJQ98_13885
LMACI6G82_08085
LYCFH508_0011280
LCAPICJ70_11740
VNTOLD84_03520
LAOAOX59_10155
LEXLen3610_00310
PSYOPB01_18360
AIAAWH56_003710
BLENNCTC4824_02855(ddh)
HYIK2M58_03845
NAMPKPF49_05730
BCOPJD108_03830
GYMGYMC10_4995
PLVERIC2_c02960(ddh)
PBDPBOR_16600
PGMPGRAT_14355
PODPODO_24560
PAENP40081_16835
PAEFR50345_24285
PAEQR50912_15705
PAEAR70723_14315
PAEER70331_13775
PAEHH70357_15910
PAEJH70737_24240
PIHUB51_02800
PRIPRIO_3117(ddh)
PSONJI735_23345
POWIJ21_02300
PXLBS614_25935
PDHB9T62_10550
PIBBBD41_20725
PCXLPB68_06065
PVOPVOR_26810
PLWD5F53_04940
PLENEIM92_01650
PLUTEI981_02905
PALBEJC50_25715
PBKBack11_45420
PPRTET464_17605
PBACHUB98_09795
PRZGZH47_15550
PLYCGXP70_01510
PTRIKDC22_14905
PALOE6C60_2624
PCELHUB94_03295
PTJJRJ22_11745
TCOTheco_1094
COHEAV92_07185
COHNKCTCHS21_54990
CCHLFPL14_10860
CHEBHH215_19600
SACAFFV09_04320
SIVSSIL_2217
SSILSOLI23_07585
SOBCSE16_10520
KURASO14_1345
KZONCTC404_02331(ddh)
SPSYAZE41_07965
SPORSporoP33_02010
SPOPSporoP37_02665
SURESporoP32a_02620
SPOSDV702_06375
SPAEE2C16_02965
SPOOJ3U78_01050
SURLBI350_06775
VIJJNUCC6_18790
NTRB0W44_04290
ESSATZ33_06345
EGVEGCR1_00605
EAVEH197_09270
ERAFJ9537_02470
THLTEH_03760(ddh)
VPIBW732_00470
VFVK5K99_09315
AURHMPREF9243_1274
AUNAWM73_03615
ASANAWM72_07700
AUHAWM75_00440
ABAECL176_04675
CRNCAR_c12320(ddh)
CAWQ783_05605
CARCNY10_629
CVDLHA31_00680
JEPBW721_07625
JEHEJN90_07205
JARG7057_06235
JPOG7058_05260
CTCCTC_02532
CTETBN906_02779
CNONT01CX_0433
CBKCLL_A3000
CBNCbC4_2183
CBTCLH_2749
CLBClo1100_0671
CBVU729_1583
CCHVBTM20_05760
CIABEN51_12255
CSEPCP523_01845
CCOHSAMEA4530647_2233(ddh)
CCAAKQH81_16810
HHJNQ487_01440
CTHCthe_0922
CTXClo1313_1295
CCLClocl_2080
HSCHVS_16175(ddh)
CCECcel_2533
RHEREHE19_006350
CSSCst_c19600(ddh2)
CSDClst_1878
CTHDCDO33_04005
FPLAA4U99_15295
RALRumal_1291
RUMCK1_20790
SMANC12CBH8_00920
BPBbpr_I0298
BFICIY_14290
BHUbhn_I0383
BCRONQ527_08190
CLEClole_2654
CEWEKH84_16090
ROBCK5_18050
BYLA4V09_13095
BHANCGC63_05045
BLAUDQQ01_04600
BPROPMF13cell1_02548(ddh)
BLABEYS05_10165
BLIQINP51_08365
BWXNQ550_05455
CPYCphy_2659
CSCIHDCHBGLK_01253(ddh)
CSHClosa_0123
CSOCLS_20310
BPRLCL2_13780
ARFAR1Y2_0013
ACACEYQ97_17455
HSDSD1D_0623(ddh)
LUAD4A81_06550
EHLEHLA_0471
RTORTO_26020
RGNRGna_07830
CBOLCGC65_18255
CASPNQ535_10570
DLOK5I24_05490
WCPH9Q76_09190
SSUNH9Q77_06990
MFORNQ534_12865
LBWC3V36_09215
PHXKGNDJEFE_01825(ddh)
STHSTH1425
CMICcaldi_23920
SWOSwol_0940
SALQSYNTR_0814
DSYDSY0242
DHDDhaf_0187
DDHDesde_0169
DDLDesdi_0152
DFGB0537_00125
HCVFTV88_2313
EHNH9Q80_11875
VGUHYG85_02875
AMIJEQM06_07400
ABUTAmi103574_11400
BPRSCK3_21290
TEPTepRe1_0343 TepRe1_2001
TAETepiRe1_0380(ddh) TepiRe1_2158(ddh)
KMEH0A61_00374(ddh)
PEDING2D1G_0503(ddh)
MHAPJFY71_09795
CADCuri_c28460(ddh)
KPARJL105_02940
VPRVpar_0329
VATB7L28_01785
VRM44547418_00350(ddh)
VDNNCTC11831_00315(ddh)
VNKVEIT17_03210
VRGOKW85_01730
DPNBCB69_04270
SSGSelsp_0198
SRISELR_03300(ddh)
SELEADJ74_06150
SELOAXE86_03395
SELTBCS37_09330
AFNAcfer_0990
AINAcin_0942
ERMEYR00_08115
LCGL3BBH23_21360
AMUOKWG62_00440
ALLOKWG61_09760
ACLACL_0763
CGLCgl2617(Cgl2617)
CGBcg2900(ddh)
CGUWA5_2528(Ddh)
CGTcgR_2525
CGSC624_12875
CGGC629_12880
CGMcgp_2900(ddh)
CGJAR0_12640
CGQCGLAR1_12505
CGXSB89_12340
CEFCE2498(ddh)
CURcu1936(ddh)
CUACU7111_1859(ddh)
CHNA605_12020
CMDB841_11040
COADR71_1201
CHMB842_11015
CMQB840_10740(ddh)
CEICEPID_10565(ddh)
CTEDCTEST_11385(ddh)
CDXCDES_11895(ddh)
CCJZccrud_11815
CSPHCSPHI_00485
CXEFOB82_06245
CRLNCTC7448_01350(ddh)
CSURN24_2703(ddh)
CCYSSAMEA4530656_0215(ddh)
CYZC3B44_09875
CAMCI6I65_08150
CKWCKALI_01995(ddh)
CCOECETAM_11400(ddh)
COKCOCCU_11815(ddh)
CFYI6L56_09035
BFVC628_12970
GOQACH46_00380
CBQAL705_02055
TOYFO059_12740
MVDAWU67_10630
MSPOKXZ72_01445
LDNH9L06_02200
LLUTK1X41_00445
ARMART_1975
ARLAFL94_00705
AAQAOC05_12210
ARYATC04_17305
ACRYAC20117_19940
ASUFMNQ99_08880
AAIAARI_01410(ddh)
GCRGcLGCM259_2435
GLUF0M17_00695
GPRJQN66_00770
GMYXH9_07830
MLUMlut_19060
MICKB1A86_00009455
MYUM8233_09045
AULDCC27_012035
BFABfae_19670
BRVCFK39_02230
BRZCFK38_09090
SANWG7063_09000
PSEIGCE65_08245
GYUFE374_00140
MCUHMPREF0573_10717
TPYCQ11_07205
TPYOX956_00505
TBWNCTC13354_00986(ddh)
TPECHLG82_10195
ASGFB03_06260
ACTTDDD63_02850
AOSAXE84_06435
ACTPB6G06_01355
ACTCCHIBA101_2093
ACTOC3V41_10850
ANEATCC27039_26750
AHWNCTC11636_02225(ddh)
AIRNCTC12972_00086(ddh)
ASLANCTC11923_00067(ddh)
AVCNCTC10951_02639(ddh)
AWEJG540_08605
AMAMHPC72_08615
AREPID810_01585
FSLEJO69_11145
FLHEJ997_12780
WIKH8R18_08795
BSUEBS3272_02775
CCUCcur_13630
ELEElen_0753
EYYEGYY_05500
EGDGS424_012715
AEQAEQU_0447
AHATADCFC_19510
RTSCE91St31_24430
ABAOBEQ56_10965
OTEOter_4154
OLEK0B96_00385
AMUAmuc_0581
AGLPYTT_1914
VBCC5Q97_19590
EMIEmin_1048
FSUFisuc_0002
FSCFSU_0395
BTHBT_1979
BTHOBtheta7330_01067(ddh)
BFRBF3690
BFSBF9343_3390
BFGBF638R_3505
BFBVU15_16515
BHLBache_3222
BOABovatus_02055(ddh)
BCELBcellWH2_01403(ddh)
BCACCGC64_17795
BCAEA4V03_13265
BZGC4H11_00340
BHFC3V43_05600
BISDXK01_021815
BUNBun01g_37060
BEGINE88_00914(ddh)
BSTEK6V31_07070
BFEK6V30_24025
BNOK8P02_13270
BHUMJXR92_016835
BVUBVU_1659
BSABacsa_2579
BDOEL88_19995
BDHGV66_08595
PCOPI6J50_17120
PGIPG_0806
PGNPGN_0830
PGTPGTDC60_1925
PAHPoras_1203
PCRENCTC12858_00444(ddh)
PCAGNCTC12856_02073(ddh)
PENDLA319_05790
PBTING2E5B_1540(ddh)
PMUCING2E5A_1339(ddh)
PETPEIBARAKI_5179
PSACPSM36_2295(ddh)
PROJKDN43_08860
DYSG7050_13290
PDIBDI_3565
PARCCI960_00940
PMERINE87_02090(ddh)
PGOLK6V26_18475
PJOLK449_00015 LK449_19295
TFOBFO_1811
TOHBCB71_06885
PARYA4V02_06740
DUNFDZ78_00785
BVSBARVI_03000
COPRCop2CBH44_30020
OSPOdosp_1546
BUYD8S85_12685
BVIRI6J59_03595
PRUPRU_2042
PMZHMPREF0659_A6106
PDNHMPREF9137_1783
PITPIN17_A1039
PDTPrede_0951
PROHMPREF0669_01219
PFUSADJ77_00730
PEOAS203_07010
PJECRM71_06410
POCNCTC13071_02708(ddh)
PNIJ5A59_02785
PMUFJ4864_00500
PHISJ5A62_01650
PCOILK433_04500
PHERprwr041_03100
PVFJ5A55_01585
PBYL6471_11645
PSCJJ4856_10935
ALQC7Y71_009490
ALDGFH31_05040
AITAI2BBH_16930
ASXCDL62_00300
ALKQM9189_04935
PSNPedsa_1251
SHTKO02_08070
MYRMYRA21_2854(ddh)
MPWMPR_1710
MODAS202_13985
MYZBK054_13535
MOAI6I89_07705
MALSNWE55_15780
TTATheth_1310
PHYAJ81_04975
DINSelin_2063
MSCHN508_001857(ddh)
NDENIDE3823
MVNMevan_0344
MAROMarbSA_08200
MHIMhar_0438
 » show all
Reference
1  [PMID:10904]
  Authors
Misono H, Togawa H, Yamamoto T, Soda K.
  Title
Occurrence of meso-alpha, epsilon-diaminopimelate dehydrogenase in Bacillus sphaericus.
  Journal
Biochem Biophys Res Commun 72:89-93 (1976)
DOI:10.1016/0006-291X(76)90964-5
Reference
2  [PMID:762012]
  Authors
Misono H, Togawa H, Yamamoto T, Soda K
  Title
Meso-alpha,epsilon-diaminopimelate D-dehydrogenase: distribution and the reaction product.
  Journal
J Bacteriol 137:22-7 (1979)
DOI:10.1128/JB.137.1.22-27.1979
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.4.1.16
IUBMB Enzyme Nomenclature: 1.4.1.16
ExPASy - ENZYME nomenclature database: 1.4.1.16
BRENDA, the Enzyme Database: 1.4.1.16
CAS: 60894-21-5

DBGET integrated database retrieval system