KEGG   ENZYME: 1.4.3.12
Entry
EC 1.4.3.12                 Enzyme                                 
Name
cyclohexylamine oxidase
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With oxygen as acceptor
Sysname
cyclohexylamine:oxygen oxidoreductase (deaminating)
Reaction(IUBMB)
cyclohexylamine + O2 + H2O = cyclohexanone + NH3 + H2O2 [RN:R02233]
Reaction(KEGG)
R02233
Substrate
cyclohexylamine [CPD:C00571];
O2 [CPD:C00007];
H2O [CPD:C00001]
Product
cyclohexanone [CPD:C00414];
NH3 [CPD:C00014];
H2O2 [CPD:C00027]
Comment
A flavoprotein (FAD). Some other cyclic amines can act instead of cyclohexylamine, but not simple aliphatic and aromatic amides.
History
EC 1.4.3.12 created 1978
Pathway
ec00930  Caprolactam degradation
ec01120  Microbial metabolism in diverse environments
Reference
1  [PMID:18451]
  Authors
Tokieda T, Niimura T, Takamura F, Yamaha T.
  Title
Purification and some properties of cyclohexylamine oxidase from a Pseudomonas sp.
  Journal
J Biochem (Tokyo) 81:851-8 (1977)
DOI:10.1093/oxfordjournals.jbchem.a131549
Other DBs
ExplorEnz - The Enzyme Database: 1.4.3.12
IUBMB Enzyme Nomenclature: 1.4.3.12
ExPASy - ENZYME nomenclature database: 1.4.3.12
UM-BBD (Biocatalysis/Biodegradation Database): 1.4.3.12
BRENDA, the Enzyme Database: 1.4.3.12
CAS: 63116-97-2

KEGG   REACTION: R02233
Entry
R02233                      Reaction                               
Name
Cyclohexylamine:oxygen oxidoreductase (deaminating)
Definition
Cyclohexylamine + Oxygen + H2O <=> Cyclohexanone + Hydrogen peroxide + Ammonia
Equation
Reaction class
RC00665  C00414_C00571
RC02755  C00007_C00027
Enzyme
Pathway
rn00930  Caprolactam degradation
rn01120  Microbial metabolism in diverse environments
Other DBs
RHEA: 18436

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