KEGG   ENZYME: 1.7.1.2
Entry
EC 1.7.1.2                  Enzyme                                 
Name
nitrate reductase [NAD(P)H];
assimilatory nitrate reductase ( ambiguous);
assimilatory NAD(P)H-nitrate reductase;
NAD(P)H bispecific nitrate reductase;
nitrate reductase (reduced nicotinamide adenine dinucleotide (phosphate));
nitrate reductase NAD(P)H;
NAD(P)H-nitrate reductase;
nitrate reductase [NAD(P)H2];
NAD(P)H2:nitrate oxidoreductase
Class
Oxidoreductases;
Acting on other nitrogenous compounds as donors;
With NAD+ or NADP+ as acceptor
Sysname
nitrite:NAD(P)+ oxidoreductase
Reaction(IUBMB)
nitrite + NAD(P)+ + H2O = nitrate + NAD(P)H + H+ [RN:R00794 R00796]
Reaction(KEGG)
R00794 R00796
Substrate
nitrite [CPD:C00088];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Product
nitrate [CPD:C00244];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
An iron-sulfur molybdenum flavoprotein.
History
EC 1.7.1.2 created 1961 as EC 1.6.6.2, transferred 2002 to EC 1.7.1.2
Pathway
ec00910  Nitrogen metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K10534  nitrate reductase (NAD(P)H)
Genes
MMER123544120
ATHAT1G37130(NIA2) AT1G77760(NIA1)
ALY9325221 9329985
CRB17895831 17897387
CSAT104702559 104713453 104742100 104743831 104751674 104757885 104777515
EUSEUTSA_v10003628mg EUTSA_v10018092mg
BRP103830551 103832206 103853097
BNA106353470 106354597 106368948 106397776 106400358 106411852 111210558
BOE106300064 106300202 106327343
RSZ108814131 108817773 108827738 108832026
THJ104813138 104813644 104817024
CPAP110815200
CIT102610866
CICCICLE_v10000220mg
PVY116131487
MINC123202651 123206115
TCC18592259
GRA105786148 105790558 105797192
GHI107908387 107910262 107922292 107951439 121229423
GAB108458123 108460813
DZI111297320 111312332 111315611
EGR104450466
GMX100813471 100818103 100818642 732634(INR2)
GSJ114381160 114383053 114383521 114415374
PVUPHAVU_008G168000g PHAVU_009G121000g
VRA106761747 106764856
VAR108320980 108329915
VUN114164208 114195673
CCAJ109787973 109793868
APRC113848520 113853291
MTRMTR_3g073150 MTR_3g073180 MTR_5g059820
CAM101498580 101509314
LJALj0g3v0006719.1(Lj0g3v0006719.1)
ADU107460801
AIP107606095
AHF112706114 112764569
LANG109328054 109360020
FVE101295234
RCN112176179
PPER18790070
PMUM103332932
PAVI110753196
PDUL117637123
MDM103401883 103439424
PXB103956697 103956979
MNT21403045
CSV101216001(NR1) 101219000(NR2) 101219242(NR3)
CMO103487560 103499266
BHJ120068130 120085245 120093002
MCHA111011766 111011787
CMAX111476969 111487583 111489182 111489275 111489277
CMOS111442711 111444943 111444944 111444945 111445293 111460569
CPEP111797396 111802114 111809152 111809170 111809173
RCU8274143
JCU105638879
HBR110647032
MESC110608013
POP7463180 7469126
PEU105116456 105120308 105127858
PALZ118041743
JRE109006417 109012439
QSU111999794 112018112 112021235 112035904 112036759
QLO115959748
TWL120009223
VVI100264320
VRI117906287 117906574
SLY100736473(NR)
SPEN107004448
SOT102577728(NR3)
CANN107867964
NTA107785409(NIA2) 107820848 107823732(NIA1)
NSY104210745 104248549
NTO104097998
NAU109206453
INI109176053
ITR116001570
SIND105171134 105176500
OEU111383770 111383771 111389106 111403601
EGT105974302
SSPL121779804 121782505 121786517 121811379
HAN110878571 110912275
ECAD122588863
LSV111893654 111902813
CCAV112504364
DCR108215759 108216720 108218952
CSIN114286364
BVG104887841
SOE110786500
CQI110714182 110725315
NNU104589330 104589753
MING122077224 122083851
TSS122656769 122663398
PSOM113346441 113356231
NCOL116262783
OSA4330867 4345795 4345798
DOSAOs02t0770800-01(Os02g0770800) Os08t0468100-01(Os08g0468100) Os08t0468700-00(Os08g0468700)
OBR102716852 102717821
BDI100827784 100829419
ATS109742560 109757553 109768384
TDC119318041 119319271 119325320 119333024 119342786
TAES123084198 123128536 123131635 123135422 123138401 123143006 123145655 123152955 123170733
SBI8055422 8078943 8083522
ZMA100383210 103643134 103654219 109939975 542278
SITA101754380 101760744
SVS117839581 117855530 117860413
PVIR120655163 120657317 120678409 120712604 120712605
PHAI112892413 112896561 112897841 112898311
PDA103710540 120108364
EGU105035363
MUS103977556 103995477 103998006
DCT110097032
PEQ110019783
ATR18423189
SMOSELMODRAFT_231924 SELMODRAFT_234494
PPP112287210 112287872 112291496
CRECHLRE_09g410950v5
VCNVOLCADRAFT_76569(nitA)
MNGMNEG_1964
CSLCOCSUDRAFT_29226 COCSUDRAFT_37154
CVRCHLNCDRAFT_56304
OLUOSTLU_37938
OTAOT_ostta10g00920
BPGBathy02g01530 Bathy02g01540
MISMICPUN_113975(nia)
MPPMICPUCDRAFT_57689(NIA) MICPUCDRAFT_70878(NIA1)
CMECYME_CMG019C
CCPCHC_T00003369001 CHC_T00008899001
BBRXBRETT_005343
OPAHPODL_02384
NCRNCU05298(nit-3)
NTENEUTE1DRAFT80350(NEUTE1DRAFT_80350)
SMPSMAC_01692 SMAC_07620
PANPODANSg6246
TTTTHITE_2115738 THITE_52692
MTMMYCTH_2299273
CTHRCTHT_0029850
MGRMGG_06062
PPEIPpBr36_02883
TMNUCRPA7_7933
SSCKSPSK_02996 SPSK_08411
FGRFGSG_01947
FPUFPSE_09169
FVRFVEG_07298 FVEG_12090
FOXFOXG_03770 FOXG_04181
NHENECHADRAFT_105480
TRETRIREDRAFT_81955
TRRM419DRAFT_93515
MAWMAC_08624
MAJMAA_01097 MAA_07503
CMTCCM_02951 CCM_08736
PLJVFPFJ_00648 VFPFJ_08944
VALVDBG_00766 VDBG_06582
VDAVDAG_00378 VDAG_05123
CFJCFIO01_10398
CHIGCH63R_03809 CH63R_04539
SAPOSAPIO_CDS10293
ELAUCREL1_11259
PFYPFICI_05019
SSLSS1G_01885
BFUBCIN_07g01270(BcniaD)
MBEMBM_01744
PSCOLY89DRAFT_596669 LY89DRAFT_709030
GLZGLAREA_01730
ANIAN1006.2 AN8449.2
AFMAFUA_1G12830 AFUA_5G10420
ACTACLA_013480 ACLA_022640
NFINFIA_012730 NFIA_076810
ANGANI_1_2088064(An07g08910) ANI_1_2090064(An07g08920) ANI_1_802074(An08g05610)
AFVAFLA_002348
ALUCAKAW2_30508S
ACHEACHE_30392A ACHE_41045A
APUUAPUU_50780S
PCSPc13g11410 Pc21g17200
PDPPDIP_28120
TMFPMAA_068110
TRGTRUGW13939_05030 TRUGW13939_09494
CIMCIMG_08017
CPWCPC735_020560
UREUREG_02306
PBLPAAG_03766 PAAG_12411(PAAG_07727)
PBNPADG_02807 PADG_03269
ABEARB_00118 ARB_06695
TVETRV_04039 TRV_06659
AJEHCAG_07200
BGHBDBG_00707 BDBG_00910
PNOSNOG_02336 SNOG_06022
PTEPTT_08192
BZECOCCADRAFT_6546
BSCCOCSADRAFT_28067
BORCOCMIDRAFT_27058
AALTCC77DRAFT_937944 CC77DRAFT_993138
ZTRMYCGRDRAFT_111003
PFJMYCFIDRAFT_206926
FFUCLAFUR5_02627 CLAFUR5_03244 CLAFUR5_05579
BCOMBAUCODRAFT_108920 BAUCODRAFT_70791
NPAUCRNP2_1295 UCRNP2_9098
TMLGSTUM_00010228001
TVSTRAVEDRAFT_47429 TRAVEDRAFT_47550
DSQDICSQDRAFT_101612 DICSQDRAFT_167737
PCOPHACADRAFT_170854
SHSSTEHIDRAFT_134312
HIRHETIRDRAFT_383634
PSQPUNSTDRAFT_121467 PUNSTDRAFT_98106
ADLAURDEDRAFT_158237 AURDEDRAFT_174664 AURDEDRAFT_177759
GTRGLOTRDRAFT_107246 GLOTRDRAFT_116849 GLOTRDRAFT_80932
LBCLACBIDRAFT_254066
MRRMoror_15986
CCICC1G_07230
CPUTCONPUDRAFT_47108
SLASERLADRAFT_437856(NR)
UMAUMAG_03847
PFPPFL1_06433
MLRMELLADRAFT_33600
ACANACA1_054310
SMINv1.2.036677.t1(symbB.v1.2.036677.t1) v1.2.039611.t1(symbB.v1.2.039611.t1)
PTIPHATRDRAFT_54983
FCYFRACYDRAFT_197330 FRACYDRAFT_206583
TPSTHAPSDRAFT_25299
AAFAURANDRAFT_53391(NIA1) AURANDRAFT_55689
PIFPITG_13012
PSOJPHYSODRAFT_337236
 » show all
Reference
1
  Authors
Nason, A.
  Title
Nitrate reductases.
  Journal
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 7, Academic Press, New York, 1963, p. 587-607.
Reference
2  [PMID:5864033]
  Authors
Paneque A, Del Campo FF, Ramirez JM, Losada M.
  Title
Flavin nucleotide nitrate reductase from spinach.
  Journal
Biochim Biophys Acta 109:79-85 (1965)
DOI:10.1016/0926-6585(65)90092-0
Reference
3  [PMID:11289301]
  Authors
Campbell WH.
  Title
Structure and function of eukaryotic NAD(P)H:nitrate reductase.
  Journal
Cell Mol Life Sci 58:194-204 (2001)
DOI:10.1007/PL00000847
Reference
4  [PMID:8534676]
  Authors
Berks BC, Ferguson SJ, Moir JW, Richardson DJ
  Title
Enzymes and associated electron transport systems that catalyse the respiratory reduction of nitrogen oxides and oxyanions.
  Journal
Biochim Biophys Acta 1232:97-173 (1995)
DOI:10.1016/0005-2728(95)00092-5
Other DBs
ExplorEnz - The Enzyme Database: 1.7.1.2
IUBMB Enzyme Nomenclature: 1.7.1.2
ExPASy - ENZYME nomenclature database: 1.7.1.2
BRENDA, the Enzyme Database: 1.7.1.2
CAS: 9029-27-0

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