KEGG   ENZYME: 1.8.7.2
Entry
EC 1.8.7.2                  Enzyme                                 
Name
ferredoxin:thioredoxin reductase
Class
Oxidoreductases;
Acting on a sulfur group of donors;
With an iron-sulfur protein as acceptor
Sysname
ferredoxin:thioredoxin disulfide oxidoreductase
Reaction(IUBMB)
2 reduced ferredoxin + thioredoxin disulfide = 2 oxidized ferredoxin + thioredoxin + 2 H+ [RN:R09502]
Reaction(KEGG)
R09502
Substrate
reduced ferredoxin [CPD:C00138];
thioredoxin disulfide [CPD:C00343]
Product
oxidized ferredoxin [CPD:C00139];
thioredoxin [CPD:C00342];
H+ [CPD:C00080]
Comment
The enzyme contains a [4Fe-4S] cluster and internal disulfide. It forms a mixed disulfide with thioredoxin on one side, and docks ferredoxin on the other side, enabling two one-electron transfers. The reduced thioredoxins generated by the enzyme activate the Calvin cycle enzymes EC 3.1.3.11 (fructose-bisphosphatase), EC 3.1.3.37
(sedoheptulose-bisphosphatase) and EC 2.7.1.19 (phosphoribulokinase) as well as other chloroplast enzymes by disulfide reduction.
History
EC 1.8.7.2 created 2010
Orthology
K17892  ferredoxin-thioredoxin reductase catalytic chain
Genes
ATHAT2G04700
ALY9319723
CRB17892001
CSAT104747147 104766506 104793886
EUSEUTSA_v10005082mg EUTSA_v10027982mg
BRP103863950
BNA106390938 106446128
BOE106337594
RSZ108849294 108851995
THJ104805419 104822811
CIT102629397
CICCICLE_v10013034mg
PVY116133144
MINC123197842 123224762
TCC18600695
GRA105768438 105798292
GHI107892308 107955570 107958593 121206521
GAB108454537 108469987
DZI111292112 111316652
EGR104422586
GMX100499945 547937(FTRC)
GSJ114382479 114400833
PVUPHAVU_004G020500g
VRA106774272
VAR108343942
VUN114182147
CCAJ109788440
APRC113867151
MTR25495243
CAM101496700
LJALj2g3v1020070.1(Lj2g3v1020070.1)
ADU107491410
AIP107643977
AHF112750738 112802525
LANG109335261 109347304 109354695
FVE101292498
RCN112188213
PPER18783723
PMUM103329919
PAVI110754713
PDUL117622103
MDM103404371 103442294
PXB103928451
ZJU107415398
MNT21387026
CSV101207663
CMO103498045
BHJ120080581
MCHA111006611
CMAX111486921 111489601
CMOS111431406 111445554
CPEP111776310 111808805
RCU8280588
JCU105642171
HBR110653440
MESC110601157 110605218
POP7496819
PEU105141677
PALZ118036912
JRE108992882
QSU112006705
QLO115973023 115976726
TWL120000461 120008884
VVI100245804
VRI117930339
SLY101268336
SPEN107011641
SOT102579143(ftrbpot)
SSTN125848168
CANN107860601
NTA107817805 107829942
NSY104215943
NTO104086082
NAU109208588
INI109158175 109178194
ITR115998975 116019271
SIND105167691 105177173
OEU111383097
EGT105960981 105968991
SSPL121767375 121769977 121789873
HAN110920670
ECAD122578421
LSV111891764 111904297
CCAV112512664 112515460
DCR108210507
CSIN114261603 114293219 114304857 114309871
BVG104908591
SOE110798481 110802350
CQI110687838 110706150 110707549 110715389
NNU104607964
MING122075898
TSS122653492
PSOM113318468 113331518
NCOL116250895
OSA4346508
DOSAOs09t0249900-01(Os09g0249900)
OBR102706226
BDI100829821
ATS109756744
TDC119319157
TAES123131556 123135361 123142907
TUA125515447
SBI8077319
ZMA542532
SITA101758781
PVIR120669620 120702941
PHAI112890170
EGU105039146 105050284
MUS103992343 103999260
DCT110096632
PEQ110023061
AOF109835774
ATR18429770
SMOSELMODRAFT_271958 SELMODRAFT_98081
PPP112280455 112281914
CRECHLRE_03g193950v5
VCNVOLCADRAFT_107576
MNGMNEG_0557
CSLCOCSUDRAFT_24815
CVRCHLNCDRAFT_53143
APROF751_4672
OLUOSTLU_18254(FTR)
OTAOT_ostta16g00420
BPGBathy07g04720
MISMICPUN_54290
MPPMICPUCDRAFT_63197
CMECymeCp194(ftrB)
CCPCHC_1145(ftrB)
TBGTbgDal_III2630
HYONNO_1809
SUNSUN_0382
SLHYH65_08780
NISNIS_0044
NAMNAMH_0217
NAPC3L23_01095
CMEDFE773_03015
CPAFC6V80_01345
DFLDFE_2205
DSDGD606_16035
DMADMR_39800
DCBC3Y92_02780
DGGDGI_1930
DDEDde_2738
DMSE8L03_06545
DSADesal_2274
DHYDESAM_21959
DAFDesaf_2376
DASDaes_1755
DPIBN4_10495
DEJAWY79_12690
PPRFDPRO_0851
PSELGM415_14430
DDNDND132_0342
PSEFPSDVSF_02780
DSXGD604_03295
PBIZLWC08_13520
DBADbac_0077
DOAAXF15_04125
DSFUWK_00919
DMLDmul_27500
DALDalk_2924
DATHRM2_41060(ftrB)
DTOTOL2_C17340
DOVDSCO28_36020
DWDDSCW_47490
DLIdnl_18860
LLUAKJ09_08171
HOHHoch_5187
SFUSfum_0349
DAXFDQ92_02510
BHTDIC78_15905
RCHRUM_16260
DRUDesru_1975
FWADCMF_10840
AFTBBF96_06455
SYNsll0554(ftrC)
SYZMYO_125420(ftrC)
SYYSYNGTS_2516(ftrC)
SYTSYNGTI_2515(ftrC)
SYSSYNPCCN_2514(ftrC)
SYQSYNPCCP_2514(ftrC)
SYJD082_19790(ftrC)
SYOC7I86_13175
SYCsyc2357_c(ftrC)
SYUM744_07810
SYFSynpcc7942_1734
SYDSyncc9605_2283
SYESyncc9902_0403
SYGsync_2484
SYRSynRCC307_2019(ftrC)
SYXSynWH7803_2151(ftrC)
SYPSYNPCC7002_A1851(ftrC)
CYACYA_2557 CYA_2601
CYBCYB_0813
SYNESyn6312_0328
SYNPSyn7502_02370
SYNKKR100_14135
SYNRKR49_06960
SYNDKR52_04740
SYHSyncc8109_2367(ftrC)
SYNWSynWH8103_00349(ftrC)
SYVAWQ23_09430
SYLAWQ21_09200
SYNCCB0101_14245
SYNYBM449_09430
DSLDacsa_1793
SYWSYNW0318(ftrC)
CGCCyagr_1536
CYICBM981_3036(ftrC)
CMPCha6605_4178
AMRAM1_4031
WNAKA717_14610
TVNNIES2134_124200(ftrC)
SLWBRW62_05250
TELtll0113(ftrC)
THNNK55_09780(ftrC)
THECFFX45_02445
LEPLepto7376_2582
LENLEP3755_16640
LETO77CONTIG1_03959(ftrC)
LBOLBWT_47800
LSCKIK02_08440
LSKJ5X98_17130
HHGXM38_052270(ftrC)
PSEUPse7367_2680
PSERABRG53_0720
THEUHPC62_10985
GLPGlo7428_0472
GENGM3709_3021
GEEGM3708_2940
CHONNIES4102_33260(ftrC)
MARMAE_51290(ftrC)
MPKVL20_1699
MIQB5D77_12655
MVZmyaer102_24280(ftrC)
CANCyan10605_0742
CSNCyast_2782
CYLAA637_12010
HAOPCC7418_2694
ENNFRE64_08885
CYUUCYN_03060
CYTcce_3398(ftrC)
CWACwatDRAFT_4221
CYPPCC8801_1523
CYHCyan8802_1550
CYCPCC7424_3748
CYJCyan7822_5020
CYNCyan7425_2504
TERTery_1567
ARPNIES39_A05620(ftrC)
PAGHNIES204_21870(ftrC)
PPSUNO713_00472(ftrC)
OXYHCG48_14460 HCG48_14990
MVAGD0A34_22495
LFSHFV01_30145
MICMic7113_4861
GEIGEI7407_0831 GEI7407_2235
OACOscil6304_5431
ONIOsc7112_0045
MPROBJP34_28305
PHORJWS08_05410
PYHNEA10_06430
CEPCri9333_3200
ANAalr4065(ftrC)
NPUNpun_R1134
NOSNos7107_5178
NOPNos7524_3878
NONNOS3756_23530
NFLCOO91_03800
NOECLI64_20265
NSHGXM_05148
NEDHUN01_11020
AVAAva_1641
NAZAazo_4385
ANBANA_C10344
ACYAnacy_4596
AWAAA650_11635
ANNEH233_08450
CSGCylst_5739
RSINB6N60_03441
CALOCal7507_6079
CALTCal6303_5618
CALHIJ00_13090
CALNNIES2098_07870
RIVRiv7116_6133
FISFIS3754_39090
NSPBMF81_04352(ftrC)
NSPHBDGGKGIB_03945(ftrC)
DOUBMF77_02616(ftrC)
DFSHGD76_04375
DHTNG743_02460
CCURIAR63_01480
CRKL3I90_03570
AFLOHEQ12_02320
TOQHCG51_23935
NCNBZZ01_31305
CTHEChro_0987
PLPPle7327_0536
SCSSta7437_3908
STANSTA3757_18260
CEOETSB_1018(ftrC)
CERRGRSB_0972(ftrC)
DEVDhcVS_187
DMGGY50_0212
DMXX792_01395
DUCUCH007_02290
TBHTbon_11975
KSTKSMBR1_1920
BROCIPI25_01215
STASTHERM_c20920
STQSpith_2137
SFCSpiaf_0363
SLRL21SP2_2972
OCKEXM22_15425
SCDSpica_1485
CTSCtha_1188
SULSYO3AOP1_0606
SAFSULAZ_0447
PMXPERMA_0689
TYETHEYE_A1879
NDENIDE3565
NMVNITMOv2_4069
NIONITINOP_0983
NJANSJP_0414
NKFNkreftii_000011
NIFW02_18140
AFGAFULGI_00017890
FPLFerp_1273
GAHGAH_01866
MBYMSBRM_1482
MBWMSBRW_1820
MBARMSBR2_0920
MBAKMSBR3_0799
MACMA_2870
MMAZMmTuc01_0064
MMJMSMAS_1271
MMACMSMAC_2622
MVCMSVAZ_1962
MEKMSKOL_1943
MLSMSLAZ_1579
METMMSMTP_1470
MEFMSWH1_1492
MEQMSWHS_1839
MSJMSSAC_2861
MSZMSSIH_2515
MSWMSSIT_2559
MTHRMSTHT_0374
MTHEMSTHC_0347
MHORMSHOH_1418
MFZAOB57_000370
MMETMCMEM_1156 MCMEM_1319
MELOJ7W08_05230
MMHMmah_0953
MHAZBHR79_08805
MEVMetev_1436
MZHMzhil_0653 Mzhil_1961
MPYMpsy_1349 Mpsy_2955
MZIHWN40_07690
MHZMetho_1811
MHUMhun_1252
MRTJKHC33_06665
MLAMlab_0211
MEMMemar_1842
MBGBN140_0547(ftrB)
MEMAMMAB1_0687
MCHKMchiMG62_21440
MPIMpet_0718
MBNMboo_2203
MFOMetfor_0517
MPLMpal_0980
MPDMCP_0977
PSYTDSAG12_01129
 » show all
Reference
1  [PMID:1910303]
  Authors
Buchanan BB
  Title
Regulation of CO2 assimilation in oxygenic photosynthesis: the ferredoxin/thioredoxin system. Perspective on its discovery, present status, and  future development.
  Journal
Arch Biochem Biophys 288:1-9 (1991)
DOI:10.1016/0003-9861(91)90157-E
Reference
2  [PMID:7628465]
  Authors
Chow LP, Iwadate H, Yano K, Kamo M, Tsugita A, Gardet-Salvi L, Stritt-Etter AL, Schurmann P
  Title
Amino acid sequence of spinach ferredoxin:thioredoxin reductase catalytic subunit and identification of thiol groups constituting a redox-active disulfide and a [4Fe-4S] cluster.
  Journal
Eur J Biochem 231:149-56 (1995)
DOI:10.1111/j.1432-1033.1995.0149f.x
  Sequence
Reference
3  [PMID:8784198]
  Authors
Staples CR, Ameyibor E, Fu W, Gardet-Salvi L, Stritt-Etter AL, Schurmann P, Knaff DB, Johnson MK
  Title
The function and properties of the iron-sulfur center in spinach ferredoxin: thioredoxin reductase: a new biological role for iron-sulfur clusters.
  Journal
Biochemistry 35:11425-34 (1996)
DOI:10.1021/bi961007p
Other DBs
ExplorEnz - The Enzyme Database: 1.8.7.2
IUBMB Enzyme Nomenclature: 1.8.7.2
ExPASy - ENZYME nomenclature database: 1.8.7.2
BRENDA, the Enzyme Database: 1.8.7.2

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