KEGG   ENZYME: 2.1.1.109
Entry
EC 2.1.1.109                Enzyme                                 
Name
demethylsterigmatocystin 6-O-methyltransferase;
demethylsterigmatocystin methyltransferase;
O-methyltransferase I
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
Sysname
S-adenosyl-L-methionine:6-demethylsterigmatocystin 6-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + 6-demethylsterigmatocystin = S-adenosyl-L-homocysteine + sterigmatocystin [RN:R03112]
Reaction(KEGG)
R03112;
(other) R10403
Substrate
S-adenosyl-L-methionine [CPD:C00019];
6-demethylsterigmatocystin [CPD:C03683]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
sterigmatocystin [CPD:C00961]
Comment
Dihydrodemethylsterigmatocystin can also act as acceptor. Involved in the biosynthesis of aflatoxins in fungi.
History
EC 2.1.1.109 created 1992
Pathway
ec00254  Aflatoxin biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K17649  demethylsterigmatocystin 6-O-methyltransferase
Genes
PANPODANSg8572
PPEIPpBr36_10627
PFYPFICI_09442
PSCOLY89DRAFT_659800
AORAO090026000025
ANGANI_1_2158014(An01g00880)
AFVAFLA_006292
ALUCAKAW2_20291A AKAW2_60089S
APUUAPUU_20054A APUU_50253S APUU_50657S
UREUREG_07660
PNOSNOG_08160
AALTCC77DRAFT_1098501
 » show all
Reference
1  [PMID:2802602]
  Authors
Yabe K, Ando Y, Hashimoto J, Hamasaki T.
  Title
Two distinct O-methyltransferases in aflatoxin biosynthesis.
  Journal
Appl Environ Microbiol 55:2172-7 (1989)
DOI:10.1128/AEM.55.9.2172-2177.1989
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.109
IUBMB Enzyme Nomenclature: 2.1.1.109
ExPASy - ENZYME nomenclature database: 2.1.1.109
BRENDA, the Enzyme Database: 2.1.1.109
CAS: 123516-47-2

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