KEGG   ENZYME: 2.1.1.210
Entry
EC 2.1.1.210                Enzyme                                 
Name
demethylspheroidene O-methyltransferase;
1-hydroxycarotenoid O-methylase;
1-hydroxycarotenoid methylase;
1-HO-carotenoid methylase;
CrtF
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
Sysname
S-adenosyl-L-methionine:demethylspheroidene O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + demethylspheroidene = S-adenosyl-L-homocysteine + spheroidene [RN:R07535]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
demethylspheroidene [CPD:C15898]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
spheroidene [CPD:C15900]
Comment
In Rhodopseudomonas capsulata and Rubrivivax gelatinosus the enzyme is involved in biosynthesis of spheroidene [1,2,3]. In Rubrivivax gelatinosus the enzyme also catalyses the methylation of demethylspirilloxanthin to spirilloxanthin and the methylation of 3,4-didehydrorhodopin to anhydrorhodovibrin [2].
History
EC 2.1.1.210 created 2011
Pathway
ec00906  Carotenoid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K09846  demethylspheroidene O-methyltransferase
Genes
ALVAlvin_2564
ATEPAtep_25170
TVIThivi_2013
TMBThimo_3007
MPURMARPU_13360
TSYTHSYN_31020
TTPE6P07_01730
THIPN838_12385
CJAPGWK36_12650
THIMKFB96_13110 KFB96_13150
TBOGLT988_08915
HHAHhal_1612
HHCM911_10360
EBSECTOBSL9_3048
PDQCL55_00013610
RACRA876_05990
LIML103DPR2_00970(crtF)
LIHL63ED372_00626(crtF)
HYRBSY239_1383
METPC1M51_03585
RGERGE_33720(crtF)
RBNRBXJA2T_09432
RDPRD2015_1035
ATERMW290_02530
METRBSY238_2446
BEBAEM42_07465
RPODE0E05_11780
AGCBSY240_3670
ABAWD5400_04840
PDESFE840_002315
BRABRADO1616(crtF)
BBTBBta_6439(crtF)
BRSS23_19160(crtF)
AOLS58_59200
BROBRAD285_5783(crtF)
BRQCIT40_23950
BGZXH91_02635
BBETF8237_24665
RPARPA1520(crtF)
RPBRPB_4003
RPCRPC_1291
RPDRPD_3758
RPERPE_1325
RPTRpal_1708
RPXRpdx1_4000
BOSBSY19_4057
MEAMex_1p2925(crtF)
MDIMETDI3494(crtF)
MEXMext_2728
MCHMchl_2955
MPOMpop_2850
MZAB2G69_21180
MRDMrad2831_2820
METM446_3695
MORMOC_3185
METAY590_13130
MAQUMaq22A_1p32535
MPHYMCBMB27_02261
MEEDA075_03950
METDC0214_15295
METXA3862_17690
METSDK389_31445
METIDK427_17905
MMESMMSR116_13605
MTEADK419_04910
MINDmvi_08960
MOGMMB17_23895
MSLMsil_2050
BBARRHAL1_03016(crtF)
RVARvan_0208
MSCBN69_3625
MBRYB1812_02310
MROSEHO51_05530 EHO51_17025
MHEYH2LOC_006870
MPARF7D14_00815
MTWCQW49_13335
CMETK6K41_01665
AUBLXB15_06390
BSBBresu_3047
BRLBZG35_15465
RUTFIU92_10165(crtF)
JANJann_0181(crtF)
RDERD1_0113(crtF)
RLIRLO149_p940140(crtF)
RPONG3256_18650
DSHDshi_3515(crtF)
REDroselon_01076
SUAMBOO69_19420
TOMBWR18_20230
RMMROSMUCSMR3_00907(crtF)
ROKRAK1035_3776
RIDRIdsm_01753(crtF_1)
ROMEI983_05430
ROHFIU89_14245(crtF)
THAACFI11_23540
MARUFIU81_13870(crtF)
ROTFIV09_18060(crtF2)
RMHLVO79_17410
MALUKU6B_16410(crtF)
RSPRSP_0264(crtF)
RSHRsph17029_1908
RSQRsph17025_2038
RSKRSKD131_1591
CAZTLV780_09085
RCPRCAP_rcc00685(crtF)
RBLB6K69_00180
PTPRCA23_c29600(crtF)
RSUNHU_04285
RHMB5V46_17495
RHCRGUI_1963
LVSLOKVESSMR4R_03677(crtF)
RBGBG454_03025
GEHHYN69_05515
TAWEI545_18935
POZI0K15_00020
NSMJO391_16455
FAQG5B39_11890
HBCAEM38_14595
NOTC7W88_00470
NGFFRF71_09135
NOGGKE62_08425
SPHITS85_22895
SSANNX02_18460
SCHYGVO57_11640
CIJWG74_05035
BLASBSY18_3553
BFWB5J99_08560
PALGHFP57_06960
PARJJ4G78_07545
SANDH3309_05740
POQKZX46_18715
ALHG6N82_11420
ELQGa0102493_111840
ERKCD351_13860
ERFFIU90_13820(crtF)
PNSA9D12_01280
PORLBG023_112668
POTE2E27_07345
AMVACMV_18810(crtF)
SRFLHU95_13845
RAPRHOA_2426(crtF)
NCBC0V82_18175
SKTIGS68_17125
SMUCJL100_008910
SROEJL101_015305
RRURru_A2982
RRFF11_15275
RCERC1_2092(crtF)
ELIOKO353_03085
GPHGEMMAAP_06530
GGRHKW67_08755
NFTFBF37_02080
 » show all
Reference
1  [PMID:12770713]
  Authors
Badenhop F, Steiger S, Sandmann M, Sandmann G
  Title
Expression and biochemical characterization of the 1-HO-carotenoid methylase CrtF from Rhodobacter capsulatus.
  Journal
FEMS Microbiol Lett 222:237-42 (2003)
DOI:10.1016/S0378-1097(03)00302-1
  Sequence
Reference
2  [PMID:12664193]
  Authors
Pinta V, Ouchane S, Picaud M, Takaichi S, Astier C, Reiss-Husson F.
  Title
Characterization of unusual hydroxy- and ketocarotenoids in Rubrivivax gelatinosus: involvement of enzyme CrtF or CrtA.
  Journal
Arch Microbiol 179:354-62 (2003)
DOI:10.1007/s00203-003-0538-3
  Sequence
[rge:RGE_33720]
Reference
3  [PMID:7358679]
  Authors
Scolnik PA, Walker MA, Marrs BL
  Title
Biosynthesis of carotenoids derived from neurosporene in Rhodopseudomonas capsulata.
  Journal
J Biol Chem 255:2427-32 (1980)
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.210
IUBMB Enzyme Nomenclature: 2.1.1.210
ExPASy - ENZYME nomenclature database: 2.1.1.210
BRENDA, the Enzyme Database: 2.1.1.210

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