KEGG ENZYME: 2.2.1.3

ENZYME: 2.2.1.3

Entry

EC 2.2.1.3                  Enzyme

Name

formaldehyde transketolase;
dihydroxyacetone synthase

Class

Transferases;
Transferring aldehyde or ketonic groups;
Transketolases and transaldolases

Sysname

D-xylulose-5-phosphate:formaldehyde glycolaldehydetransferase

Reaction(IUBMB)

D-xylulose 5-phosphate + formaldehyde = D-glyceraldehyde 3-phosphate + glycerone [RN:R01440]

Reaction(KEGG)

R01440;
(other) R06861 R06862

Substrate

D-xylulose 5-phosphate [CPD:C00231];
formaldehyde [CPD:C00067]

Product

D-glyceraldehyde 3-phosphate [CPD:C00118];
glycerone [CPD:C00184]

Comment

A thiamine-diphosphate protein. Not identical with EC 2.2.1.1 transketolase. Also converts hydroxypyruvate and formaldehyde into glycerone and CO2.

History

EC 2.2.1.3 created 1984

Pathway

ec00680

Methane metabolism

ec01100

Metabolic pathways

ec01120

Microbial metabolism in diverse environments

Orthology

K17100

dihydroxyacetone synthase

Genes

QSU:	111983346 112009536 112031215

PPA:	PAS_chr3_0832 PAS_chr3_0834

DHA:	DEHA2B00616g DEHA2F00968g

PIC:	PICST_53327(DHA1)

PGU:	PGUG_01217

CTEN:

CANTEDRAFT_131235

SLB:	AWJ20_4479(TKL1)

OPA:	HPODL_02162 HPODL_04602

MGR:

MGG_09856

PPEI:

PpBr36_04039

TMN:	UCRPA7_3396 UCRPA7_4269

FGR:	FGSG_04065

FPU:	FPSE_05207

FVR:	FVEG_09977 FVEG_10248

FOX:	FOXG_11576 FOXG_11937

NHE:	NECHADRAFT_49818 NECHADRAFT_81279 NECHADRAFT_85417 NECHADRAFT_94736

TRE:	TRIREDRAFT_2211

TRR:	M419DRAFT_131902

PLJ:	VFPFJ_03124

VAL:	VDBG_01162

VDA:	VDAG_00766

CFJ:	CFIO01_03804

CHIG:

CH63R_06688 CH63R_13541

SAPO:

SAPIO_CDS4846 SAPIO_CDS9476

ELA:	UCREL1_10531 UCREL1_1117

PFY:	PFICI_04079 PFICI_09160 PFICI_10610

BFU:	BCIN_03g03550

PSCO:

LY89DRAFT_706556

GLZ:	GLAREA_06711

ANI:	AN8551.2 AN8935.2

AFM:	AFUA_3G02910

NFI:	NFIA_003880 NFIA_004690

AOR:	AO090001000322 AO090023000345

ANG:	ANI_1_510124(An14g03500)

AFV:	AFLA_006693 AFLA_008666

ALUC:

AKAW2_41032A AKAW2_80002A

ACHE:

ACHE_70026A

APUU:

APUU_30076S APUU_61016S APUU_80790S

PCS:	Pc13g02010 Pc14g00180 Pc15g01110

TMF:	PMAA_002290

TRG:	TRUGW13939_01504 TRUGW13939_05090

PNO:	SNOG_09852

PTE:

PTT_19509

BZE:	COCCADRAFT_102944

BSC:	COCSADRAFT_77503

BOR:	COCMIDRAFT_102603

AALT:

CC77DRAFT_1033210 CC77DRAFT_924107

ZTR:	MYCGRDRAFT_86253

PFJ:	MYCFIDRAFT_216533

FFU:	CLAFUR5_08012

BCOM:

BAUCODRAFT_75705

NPA:	UCRNP2_5919

CNE:	CNE00140 CNM01730

CNB:	CNBE0050 CNBM1610

CNG:	CNAG_02552 CNAG_06172

CGI:	CGB_L0060W CGB_M2360C

TMS:	TREMEDRAFT_68833

SHS:	STEHIDRAFT_149842

MRR:	Moror_11317

SCM:	SCHCODRAFT_77046

PFP:	PFL1_02180

» show all

Reference

1 [PMID:7249920]

Authors

Bystrykh LV, Sokolov AP, Trotsenko IuA.

Title

[Separation of transketolase and dihydroxyacetone synthase from methylotrophic yeasts]

Journal

Dokl Akad Nauk SSSR 258:499-501 (1981)

Reference

2 [PMID:7074134]

Authors

Kato N, Higuchi T, Sakazawa C, Nishizawa T, Tani Y, Yamada H

Title

Purification and properties of a transketolase responsible for formaldehyde fixation in a methanol-utilizing yeast, candida boidinii (Kloeckera sp.) No. 2201.

Journal

Biochim Biophys Acta 715:143-50 (1982)
DOI:10.1016/0304-4165(82)90352-X

Reference

3 [PMID:6276498]

Authors

Waites MJ, Quayle JR.

Title

The interrelation transketolase and dihydroxyacetone synthase activities in the methylotrophic yeast Candida boidinii.

Journal

J Gen Microbiol 124:309-16 (1981)
DOI:10.1099/00221287-124-2-309

Other DBs

ExplorEnz - The Enzyme Database:

2.2.1.3

IUBMB Enzyme Nomenclature:

2.2.1.3

ExPASy - ENZYME nomenclature database:

2.2.1.3

BRENDA, the Enzyme Database:

2.2.1.3

CAS:	124566-23-0

DBGET integrated database retrieval system