Entry
Name
formaldehyde transketolase;
dihydroxyacetone synthase
Class
Transferases;
Transferring aldehyde or ketonic groups;
Transketolases and transaldolases
BRITE hierarchy
Sysname
D-xylulose-5-phosphate:formaldehyde glycolaldehydetransferase
Reaction(IUBMB)
D-xylulose 5-phosphate + formaldehyde = D-glyceraldehyde 3-phosphate + glycerone [RN:
R01440 ]
Reaction(KEGG)
Substrate
D-xylulose 5-phosphate [CPD:
C00231 ];
formaldehyde [CPD:
C00067 ]
Product
D-glyceraldehyde 3-phosphate [CPD:
C00118 ];
glycerone [CPD:
C00184 ]
Comment
A thiamine-diphosphate protein. Not identical with EC
2.2.1.1 transketolase. Also converts hydroxypyruvate and formaldehyde into glycerone and CO2.
History
EC 2.2.1.3 created 1984
Pathway
ec01120 Microbial metabolism in diverse environments
Orthology
K17100 dihydroxyacetone synthase
Genes
QSU : 111983346 112009536 112031215
PPA : PAS_chr3_0832 PAS_chr3_0834
DHA : DEHA2B00616g DEHA2F00968g
OPA : HPODL_02162 HPODL_04602
TMN : UCRPA7_3396 UCRPA7_4269
FVR : FVEG_09977 FVEG_10248
FOX : FOXG_11576 FOXG_11937
NHE : NECHADRAFT_49818 NECHADRAFT_81279 NECHADRAFT_85417 NECHADRAFT_94736
CHIG : CH63R_06688 CH63R_13541
SAPO : SAPIO_CDS4846 SAPIO_CDS9476
ELA : UCREL1_10531 UCREL1_1117
PFY : PFICI_04079 PFICI_09160 PFICI_10610
NFI : NFIA_003880 NFIA_004690
AOR : AO090001000322 AO090023000345
ANG : ANI_1_510124(An14g03500)
AFV : AFLA_006693 AFLA_008666
ALUC : AKAW2_41032A AKAW2_80002A
APUU : APUU_30076S APUU_61016S APUU_80790S
PCS : Pc13g02010 Pc14g00180 Pc15g01110
TRG : TRUGW13939_01504 TRUGW13939_05090
AALT : CC77DRAFT_1033210 CC77DRAFT_924107
CNG : CNAG_02552 CNAG_06172
CGI : CGB_L0060W CGB_M2360C
» show all
Taxonomy
Reference
Authors
Bystrykh LV, Sokolov AP, Trotsenko IuA.
Title
[Separation of transketolase and dihydroxyacetone synthase from methylotrophic yeasts]
Journal
Dokl Akad Nauk SSSR 258:499-501 (1981)
Reference
Authors
Kato N, Higuchi T, Sakazawa C, Nishizawa T, Tani Y, Yamada H
Title
Purification and properties of a transketolase responsible for formaldehyde fixation in a methanol-utilizing yeast, candida boidinii (Kloeckera sp.) No. 2201.
Journal
Reference
Authors
Waites MJ, Quayle JR.
Title
The interrelation transketolase and dihydroxyacetone synthase activities in the methylotrophic yeast Candida boidinii.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 2.2.1.3
ExPASy - ENZYME nomenclature database: 2.2.1.3
BRENDA, the Enzyme Database: 2.2.1.3