| Entry |
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| Name |
formaldehyde transketolase;
dihydroxyacetone synthase
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| Class |
Transferases;
Transferring aldehyde or ketonic groups;
Transketolases and transaldolases
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| Sysname |
D-xylulose-5-phosphate:formaldehyde glycolaldehydetransferase
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| Reaction(IUBMB) |
D-xylulose 5-phosphate + formaldehyde = D-glyceraldehyde 3-phosphate + glycerone [RN: R01440]
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| Reaction(KEGG) |
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| Substrate |
D-xylulose 5-phosphate [CPD: C00231];
formaldehyde [CPD: C00067]
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| Product |
D-glyceraldehyde 3-phosphate [CPD: C00118];
glycerone [CPD: C00184]
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| Comment |
A thiamine-diphosphate protein. Not identical with EC 2.2.1.1 transketolase. Also converts hydroxypyruvate and formaldehyde into glycerone and CO2.
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| History |
EC 2.2.1.3 created 1984
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| Pathway |
| ec01120 | Microbial metabolism in diverse environments |
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| Orthology |
| K17100 | dihydroxyacetone synthase |
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| Genes |
» show all
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| Reference |
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| Authors |
Bystrykh LV, Sokolov AP, Trotsenko IuA. |
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| Title |
[Separation of transketolase and dihydroxyacetone synthase from methylotrophic yeasts] |
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| Journal |
Dokl Akad Nauk SSSR 258:499-501 (1981) |
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| Reference |
|
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| Authors |
Kato N, Higuchi T, Sakazawa C, Nishizawa T, Tani Y, Yamada H |
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| Title |
Purification and properties of a transketolase responsible for formaldehyde fixation in a methanol-utilizing yeast, candida boidinii (Kloeckera sp.) No. 2201. |
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| Journal |
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| Reference |
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| Authors |
Waites MJ, Quayle JR. |
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| Title |
The interrelation transketolase and dihydroxyacetone synthase activities in the methylotrophic yeast Candida boidinii. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.2.1.3 |
| ExPASy - ENZYME nomenclature database: | 2.2.1.3 |
| BRENDA, the Enzyme Database: | 2.2.1.3 |
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