C40-phthioceranyl-[(hydroxy)phthioceranic acid synthase] [CPD:C22125];
C37-phthioceranyl-[(hydroxy)phthioceranic acid synthase] [CPD:C22126]
This mycobacterial polyketide enzyme produces the hepta- and octa-methylated fatty acids known as phthioceranic acids, and presumably their hydroxylated versions. Formation of hepta- and octamethylated products depends on whether the enzyme incorporates seven or eight methylmalonyl-CoA extender units, respectively. Formation of hydroxylated products may result from the enzyme skipping the dehydratase (DH) and enoylreductase (ER) domains during the first cycle of condensation .