KEGG   ENZYME: 2.3.1.304
Entry
EC 2.3.1.304                Enzyme                                 

Name
poly[(R)-3-hydroxyalkanoate] polymerase;
PHA synthase;
phaC (gene name);
PhaE
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
poly(R)-3-hydroxyalkanoate (3R)-3-hydroxyacyltransferase
Reaction(IUBMB)
(3R)-3-hydroxyacyl-CoA + poly[(R)-3-hydroxyalkanoate]n = CoA + poly[(R)-3-hydroxyalkanoate]n+1 [RN:R12791]
Reaction(KEGG)
R12791;
(other) R04254
Substrate
(3R)-3-hydroxyacyl-CoA [CPD:C01086];
poly[(R)-3-hydroxyalkanoate]n [CPD:C22398]
Product
CoA [CPD:C00010];
poly[(R)-3-hydroxyalkanoate]n+1 [CPD:C22398]
Comment
This is the key enzyme in the biosynthesis of polyhydroxyalkanoates (PHA), linear polyesters produced by bacteria as a means of carbon and energy storage [6]. The enzyme catalyses the stereoselective, covalent linkage of (3R)-3-hydroxyacyl-CoA thioesters in a transesterification reaction with concomitant release of coenzyme A. The growing polymer is attached to a conserved active site L-cysteine residue. Three types of PHA synthases have been proposed based on their substrate specificity and enzyme structure. Type I and type III synthases preferentially polymerize short chain hydroxyalkanoate monomers containing 3-5 carbon atoms [1,2]. The difference between these two types is that type I synthases are composed of only a single subunit (PhaC), whereas type III synthases are composed of two different subunits, PhaC and PhaE [3,5]. Type II synthases are also composed of a single subunit (PhaC), but preferentially polymerize monomers containing more than 5 carbon atoms [4].
History
EC 2.3.1.304 created 2021
Pathway
ec00650  Butanoate metabolism
ec01100  Metabolic pathways
Orthology
K03821  poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaC
Genes
PSHI: SAMEA2665130_2778(phbC)
XCC: XCC2159(phbC)
XCB: XC_1959
XCA: xcc-b100_2022
XCP: XCR_2428
XCV: XCV2209(phbC)
XAX: XACM_2154(phbC)
XAC: XAC2048(phbC)
XCI: XCAW_01775
XCT: J151_02207
XOM: XOO2086(XOO2086)
XOO: XOO2221(phbC)
XOP: PXO_00929
XOR: XOC_2654
XAL: XALC_1638(phbC)
XPH: XppCFBP6546_01815(XppCFBP6546P_01815)
XCZ: EBN15_10985(phaC)
SML: Smlt2964(phaC)
SMT: Smal_2415
SMZ: SMD_2605(phbC)
SACZ: AOT14_17520(phaC_1) AOT14_21230(phbC_1) AOT14_32460(phbC_2)
SINC: DAIF1_25620(phaC)
SPAQ: STNY_R26600(phaC)
PSUW: WQ53_01095
LAB: LA76x_2372(phaC)
LAQ: GLA29479_2762(phaC)
LCP: LC55x_2390(phaC)
LGU: LG3211_2847(phaC)
LEZ: GLE_2858(phaC)
LEM: LEN_2173(phbC)
LSOL: GOY17_07360(phaC)
LHX: LYSHEL_24990(phbC)
LCAS: LYSCAS_24990(phbC)
LUG: FPZ22_12960(phaC)
THES: FHQ07_01730(phaC)
THEH: G7079_08440(phaC)
RGL: CS053_09325(phaC)
DKO: I596_2422
VCH: VC_A0688
VCS: MS6_A0735
VCE: Vch1786_II0372(phaC)
VCI: O3Y_16758
VCO: VC0395_0628(phaC)
VCR: VC395_A0624(phaC)
VCM: VCM66_A0646(phaC)
VCX: VAA049_2260(phaC)
VCZ: VAB027_486(phaC)
VVU: VV2_0739
VVY: VVA1208
VPA: VPA1202
VAG: N646_3911
VSP: VS_II0587
VNI: VIBNI_B1304(phaC)
VEU: IXK98_07690(phaC)
VSC: VSVS12_03822(phbC)
VTA: B0497(phbC)
VAF: D1115_20265(phaC)
VNL: D3H41_20180(phaC)
VCC: FAZ90_21005(phaC)
VAS: GT360_20005(phaC)
VAQ: FIV01_20295(phbC)
VSR: Vspart_03888(phbC)
VKA: BTD91_19640(phaC)
VNV: IF132_05495(phaC)
PPR: PBPRB0352(PHAC) PBPRB1838(PHAC)
PGH: FH974_19305(phaC)
SALY: E8E00_10380(phaC)
SKS: FCN78_03120(phaC)
SCOT: HBA18_03295(phaC)
PAE: PA5056(phaC1) PA5058(phaC2)
PAEV: N297_5229(phaC) N297_5231(phaC)
PAEI: N296_5229(phaC) N296_5231(phaC)
PAU: PA14_66820(phaC1) PA14_66840(phaC2)
PAP: PSPA7_5794(phaC1) PSPA7_5797(phaC2)
PAG: PLES_54461(phaC1) PLES_54481(phaC2)
PAF: PAM18_5171(phaC1) PAM18_5173(phaC2)
PNC: NCGM2_0453(phaC2) NCGM2_0455(phaC1)
PAEB: NCGM1900_5812(phaC1) NCGM1900_5814(phaC2)
PAEU: BN889_05614(phaC1) BN889_05617(phaC2_2)
PAEC: M802_5227(phaC) M802_5229(phaC)
PAEO: M801_5094(phaC) M801_5096(phaC)
PRE: PCA10_33800(phaC) PCA10_52770(phaC1) PCA10_52790(phaC2)
PPSE: BN5_0412(phaC2) BN5_0414(phaC1) BN5_4105(phaC5)
PCQ: PcP3B5_05840(phbC_1) PcP3B5_05860(phbC_2)
PMUI: G4G71_00385(phaC) G4G71_00395(phaC)
PPU: PP_5003(phaA) PP_5005(phaC-II)
PPB: PPUBIRD1_4791(phaA) PPUBIRD1_4793(phaC)
PPX: T1E_5658(phaA) T1E_5660(phaC)
PPUN: PP4_50700(phaC1) PP4_50720(phaC2)
PST: PSPTO_5145(phaC)
PSYR: N018_23795
PVD: CFBP1590__4930(phaA) CFBP1590__4932(phaC)
PFL: PFL_0432(phaC) PFL_0434(phaA)
PPRC: PFLCHA0_c04390(phaC1) PFLCHA0_c04410(phaA)
PPRO: PPC_0446 PPC_0448(phaA)
PFE: PSF113_0411(phaC2) PSF113_0413(phaC1)
PFS: PFLU_0394(phaC) PFLU_0396(phaA)
PFC: PflA506_0386(phaC) PflA506_0388(phaA)
PMAN: OU5_0378(phaC) OU5_3069(phaC1) OU5_3071(phaC2) OU5_P0127
PRX: HRH33_02905(phaC) HRH33_02915(phaC)
PEN: PSEEN5066(phaC1) PSEEN5068(phaC2)
PSA: PST_0683(phaC)
PPUU: PputUW4_00331(phaC2) PputUW4_00333(phaC1_1) PputUW4_02300(phaC1_2)
PKC: PKB_0464(phaC) PKB_0466(phaA)
PSEC: CCOS191_0482(phaC) CCOS191_0484(phaA)
PSOS: POS17_0423 POS17_0425(phaA)
POJ: PtoMrB4_52190(phaC1) PtoMrB4_52210(phaC2)
PSEJ: HNQ25_21870(phaC) HNQ25_21880(phaC)
PVK: EPZ47_01970(phaC) EPZ47_01980(phaC)
PEZ: HWQ56_02260(phaC) HWQ56_02270(phaC)
PBZ: GN234_16065(phaC) GN234_16075(phaC)
PKH: JLK41_02525(phaC) JLK41_02535(phaC)
PTY: JWV26_13280(phaC) JWV26_13295(phaC)
PMAO: PMYSY11_4139(phaC) PMYSY11_4141(phaC)
PATA: JWU58_25440(phaC) JWU58_25450(phaC)
PDW: BV82_2658(phaC) BV82_2660(phaC)
PZE: HU754_003070(phaC) HU754_003080(phaC)
PMOE: HV782_003000(phaC) HV782_003010(phaC)
PVW: HU752_002960(phaC) HU752_002970(phaC)
PTRT: HU722_0002885(phaC) HU722_0002895(phaC)
PXA: KSS93_04085(phaC) KSS93_04095(phaC)
PSAM: HU731_018020(phaC) HU731_018030(phaC)
PTZ: HU718_002985(phaC) HU718_002995(phaC)
PQI: KH389_01885(phaC) KH389_01895(phaC)
PSHH: HU773_002685(phaC) HU773_002695(phaC)
PXN: HU772_022865(phaC) HU772_022875(phaC)
PHV: HU739_015610(phaC) HU739_015620(phaC)
PPRG: HU725_021035(phaC) HU725_021045(phaC)
PANH: HU763_022440(phaC) HU763_022450(phaC)
PASG: KSS96_02925(phaC) KSS96_02935(phaC)
PFAK: KSS94_24875(phaC) KSS94_24885(phaC)
PMUY: KSS95_05000(phaC) KSS95_05010(phaC)
PMAM: KSS90_23380(phaC) KSS90_23390(phaC)
PAZE: KSS91_02450(phaC) KSS91_02460(phaC)
PALV: KSS97_03085(phaC) KSS97_03095(phaC)
PORY: EJA05_26025(phaC) EJA05_26040(phaC)
ACX: Achr_22910(phbC) Achr_5170
MHC: MARHY1500(phbC) MARHY3725
MBS: MRBBS_1804(phaC)
MARA: D0851_03930(phaC) D0851_07245(phaC)
MARJ: MARI_28790
ACB: A1S_2222
ABM: ABSDF1303
ABY: ABAYE1308
ABN: AB57_2581
ABB: ABBFA_01203(phbC_1)
ABX: ABK1_1262
ABH: M3Q_2693
ABAD: ABD1_22210
ABAZ: P795_5830
ABAU: IX87_07145
ABAA: IX88_13740
ACC: BDGL_001729(phaC1)
SPL: Spea_1752
SHL: Shal_1987
SPSH: FM037_24825(phaC) FM037_25870(phaC)
CPS: CPS_4088(phbC)
PSEO: OM33_20835
PSEN: PNC201_12605(phbC)
PXI: J5O05_13395(phaC)
PVB: J5X90_00120(phaC)
ALR: DS731_19115(phaC)
APEL: CA267_007325(phaC)
SALM: D0Y50_01510(phaC)
SALK: FBQ74_15780(phaC)
GNI: GNIT_0410(phbC) GNIT_3411(phbC)
PAEW: KIH87_11385(phaC)
FBL: Fbal_0387
SDE: Sde_1326
TTU: TERTU_2758(phaC)
SAGA: M5M_15147
ALG: AQULUS_00710(phbC_1) AQULUS_20510(phbC_2)
ASIP: AQUSIP_00790(phbC_1) AQUSIP_22860(phbC_2)
LPN: lpg0599 lpg1058(phbC) lpg1097(phbC) lpg2260(phbC)
LPH: LPV_0709(phbC) LPV_1748 LPV_2533(phbC)
LPO: LPO_0671(phbC) LPO_2335(phbC) LPO_2821
LPM: LP6_0581(phbC2) LP6_1041(phaC) LP6_1079(phbC) LP6_2289(phbC1)
LPC: LPC_1543 LPC_1729(phbC) LPC_2216(phbC) LPC_2700(phbC)
LLO: LLO_2080(phbC) LLO_2383(phbC) LLO_2729
LFA: LFA_3121(phbC) LFA_3381(phaC) LFA_pA0054(phbC)
LHA: LHA_0095 LHA_2914(phaC)
LOK: Loa_00564(phbC1) Loa_00589(phbC2) Loa_00695
LCD: clem_01840(phbC_1) clem_08320(phbC_2) clem_14470(phbC_3)
LLG: 44548918_00037(phbC_1) 44548918_00444(phbC_2) 44548918_02006(phbC_3) 44548918_02419(phbC_4)
LGT: E4T54_04145(phaC)
LJR: NCTC11533_00037(phbC_1) NCTC11533_00752(phbC_2) NCTC11533_02586(phbC_3)
LCJ: NCTC11976_02013(phbC_1) NCTC11976_03289(phbC_5)
LSS: NCTC12082_01703(phbC_1) NCTC12082_01763(phbC_2) NCTC12082_02474(phbC_3)
LADL: NCTC12735_00523(phbC_1) NCTC12735_01924(phbC_2)
MISZ: MishRS11D_03780(phbC)
ATEP: Atep_02350(phbC)
TTP: E6P07_09810(phaC)
THIP: N838_24370
TGR: Tgr7_1512
TNI: TVNIR_1245(phbC_[H])
GAI: IMCC3135_12585(phbC_1) IMCC3135_23480(phbC_2) IMCC3135_33995(phbC_3)
CSA: Csal_2463
HEL: HELO_3394(phbC)
HCO: LOKO_00815(phbC_1) LOKO_00881(phbC_2)
HBE: BEI_0862(phbC1) BEI_2363(phbC2) BEI_2537(phbC3) BEI_2618(phbC4)
HVN: EI420_06025(phaC)
HTT: HZS52_13420(phaC)
HPIZ: GYM47_05820(phaC)
KUY: FY550_04245(phaC)
ABO: ABO_1418(phaC2) ABO_2214(phaC1)
ADI: B5T_02346(phaC2)
TOL: TOL_2313
VCW: GJQ55_04310(phaC)
AHA: AHA_2421
ASA: ASA_2280(phaC)
AMED: B224_2078
ACAV: VI35_11525
AEL: NCTC12917_02267(phbC)
TAU: Tola_2475
OCE: GU3_11240
NSG: H3L94_04090(phaC)
PTES: JQU52_14115(phaC)
CVI: CV_2789(phaC)
CRZ: D1345_08255(phaC)
CHAE: CH06BL_17820(phbC)
LHK: LHK_01111(phaC)
AMAH: DLM_2473
VOG: LCH97_02230(phaC)
RSO: RSc1631(phbC)
RSC: RCFBP_11639(phaC)
RSL: RPSI07_1724(phaC)
RSN: RSPO_c01711(phbC) RSPO_m01422(phaC)
RSM: CMR15_11634(phaC)
RSE: F504_1705
RSY: RSUY_20760(phbC_1)
RSG: JK151_06170(phaC)
REH: H16_A1437(phaC1) H16_A2003(phaC2)
CNC: CNE_1c14650(phaC) CNE_1c18420(phaA2)
RME: Rmet_1356(phaC1) Rmet_1671(phaC2) Rmet_5122(phaC3)
CTI: RALTA_A1350(phaC1) RALTA_B0468(phaC2)
CGD: CR3_1571(phbC)
BMA: BMA1322(phaC) BMAA0122(phbC)
BMV: BMASAVP1_1287(phbC) BMASAVP1_A1811(phaC)
BML: BMA10229_A0085(phbC)
BMN: BMA10247_1082(phbC-2) BMA10247_A0146(phbC-1)
BMAL: DM55_3170(phbC) DM55_3589
BMAE: DM78_1654(phbC) DM78_4482
BMAQ: DM76_3154(phbC) DM76_4284
BMAF: DM51_1042(phbC) DM51_3883
BMAZ: BM44_2011(phbC) BM44_3548
BMAB: BM45_1575(phbC)
BPS: BPSL1534(phbC) BPSS1954
BPD: BURPS668_2166(phbC) BURPS668_A2797(phbC)
BPR: GBP346_A2274(phbC_1)
BPSE: BDL_5362 BDL_81(phbC)
BPSM: BBQ_1405(phbC) BBQ_4175
BPSU: BBN_1529(phbC) BBN_5421
BPSD: BBX_2017(phbC) BBX_4527
BPK: BBK_3031(phbC) BBK_4694
BPSH: DR55_2649(phbC) DR55_5779
BPSA: BBU_230(phbC) BBU_4054
BPSO: X996_2240(phbC) X996_5579
BUT: X994_5140 X994_667(phbC)
BTQ: BTQ_1664(phbC) BTQ_3711
BTJ: BTJ_4745 BTJ_691(phbC)
BTZ: BTL_1930(phbC) BTL_5531
BTD: BTI_1748(phbC) BTI_5039
BTV: BTHA_2085(phbC) BTHA_4671
BTHE: BTN_2836(phbC) BTN_5201
BTHM: BTRA_2213(phbC) BTRA_5471
BTHL: BG87_2155(phbC) BG87_5543
BOK: DM82_1470(phbC) DM82_6246
BOC: BG90_3239(phbC) BG90_4421
BVE: AK36_2126(phbC) AK36_5756
BCN: Bcen_6288
BCJ: BCAL1863(phbC) BCAM0297
BCEN: DM39_1753(phbC)
BCEW: DM40_2389(phbC) DM40_4418
BCEO: I35_1781(phbC)
BMJ: BMULJ_01759(phbC) BMULJ_05631(phbC)
BMK: DM80_3236(phbC) DM80_6341
BMUL: NP80_1851(phbC)
BCT: GEM_1635
BCED: DM42_3311(phbC) DM42_4866
BDL: AK34_1334(phbC) AK34_5116
BUB: BW23_3194(phbC) BW23_6080
BSTG: WT74_09395
BANN: JFN94_09005(phaC)
BGU: KS03_2439(phbC) KS03_3889
BGO: BM43_3586(phbC)
BUL: BW21_1841(phbC) BW21_4576
BGP: BGL_1c22190(phbC)
BFN: OI25_3391(phbC) OI25_7487
PSPW: BJG93_05770(phaC) BJG93_18250(phaC)
PGIS: I6I06_04695(phaC)
PACS: FAZ98_07290(phaC)
PEW: KZJ38_10200(phaC)
PNU: Pnuc_0923
PNE: Pnec_0919
PPUL: RO07_22935
HYF: DTO96_102206(phaC)
LMIR: NCTC12852_01829(phbC)
CABA: SBC2_20720(phaC)
BPE: BP1149(phbC)
BPC: BPTD_1141(phbC)
BPER: BN118_1579(phbC)
BPET: B1917_2705(phbC)
BPEU: Q425_10790(phbC)
BPAR: BN117_3160(phbC)
BPA: BPP3196(phbC)
BBH: BN112_4768(phbC)
BBR: BB3596(phbC)
BBM: BN115_3319(phbC)
BBX: BBS798_3427(phbC)
BPT: Bpet1849(phbC)
BAV: BAV1221(phbC)
BHO: D560_2435(phbC)
BHM: D558_2416(phbC)
BHZ: ACR54_02555(phbC_1) ACR54_03199(phbC_2)
BTRM: SAMEA390648702701(phbC_1) SAMEA390648703356(phbC_2)
AXY: AXYL_01665(phaC)
AXX: ERS451415_01562(phbC_1) ERS451415_05448(phbC_2)
ACHB: DVB37_06610(phaC)
ADY: HLG70_14570(phaC)
PUT: PT7_0440
PUD: G9Q38_12910(phaC)
AMIM: MIM_c13530(phaC)
ODI: ODI_R2858
OUE: I6G29_03750(phaC)
PIG: EGT29_13010(phaC)
PACR: FXN63_10295(phaC)
PARK: LSG25_08935(phaC)
RHG: EXZ61_07875(phaC)
POS: DT070_19510(phaC)
POO: F7R28_11060(phaC)
PVAC: HC248_01595(phaC_2)
AAV: Aave_2477
AJS: Ajs_2074
AAA: Acav_2735
ACRA: BSY15_3416(phbC)
AANT: HUK68_09555(phaC)
VEI: Veis_3819
DAC: Daci_3600
RTA: Rta_18090(phbC)
LIM: L103DPR2_01574(phbC)
LIH: L63ED372_01994(phbC)
HYR: BSY239_1485(phbC)
HPSE: HPF_14790(phbC)
HYN: F9K07_13665(phaC)
DIH: G7047_09285(phaC)
DRG: H9K76_11295(phaC)
KIA: G8A07_07930(phaC)
HAR: HEAR1923(phbC) HEAR2340
MMS: mma_1396(phbC)
JAG: GJA_2135(phbC)
HSE: Hsero_2405(phbC) Hsero_2999(phbC)
HRB: Hrubri_3020(phbC)
HHF: E2K99_15405(phaC)
HFR: G5S34_16025(phaC)
CFU: CFU_1775(phbC)
CARE: LT85_2876
CPRA: CPter91_2317(phbC)
MALI: EYF70_14310(phaC)
MUM: FCL38_04345(phaC)
DUG: HH213_24155(phaC)
GLC: JQN73_00440(phaC)
THI: THI_1476 THI_1639(phbC1)
RGE: RGE_03900(phbC) RGE_23750(phbC)
XYK: GT347_04120(phaC)
TTW: LCC91_05560(phaC)
BBAG: E1O_22710
PBH: AAW51_0789(phbC) AAW51_2905(phbC)
METR: BSY238_1707(phaC) BSY238_62(phbC)
DOE: DENOEST_0138(phaC) DENOEST_1592(phaC) DENOEST_2491(phaC)
URU: DSM104443_02037(phaC_1) DSM104443_02571(phaC_2)
UPL: DSM104440_02307(phaC)
OTR: OTERR_01790(phbC) OTERR_08260(phbC) OTERR_12250(phbC)
EBA: ebA3628(phbC) ebA4728(phbC) ebA5073(phbC) ebA5140(phbC) ebA6212(phbC)
ABRE: pbN1_04950(phaC1) pbN1_05390(phaC2) pbN1_07420(phbC) pbN1_22120(phaC4) pbN1_37560
APET: ToN1_29850(phaC1) ToN1_36950 ToN1_37340(phaC2)
AZO: azo0389(phbC1) azo1021(phaC) azo1350(phbC2)
AZA: AZKH_0507(phbC) AZKH_3140(phbC) AZKH_3211(phbC) AZKH_p0452(phbC)
BPRC: D521_0919
DML: Dmul_05680(phbC) Dmul_15280(phbC)
DAT: HRM2_42100(phaC)
DTO: TOL2_C36990(phbC)
DOV: DSCO28_09750(phbC_1) DSCO28_30760(phbC_2)
DALK: DSCA_38110(phbC)
DLI: dnl_20450 dnl_32680(phaC)
DMM: dnm_047750(phaC)
MXA: MXAN_6874(phaC)
SCL: sce0309
RPR: RP738(RP738) RP820(RP820)
RPQ: rpr22_CDS718(phbC) rpr22_CDS800(phaC)
RTY: RT0723 RT0808(phbC)
RCM: A1E_04750
RBE: RBE_0140(phbC) RBE_0173
RFE: RF_0162(phbC) RF_1298(phaC)
RRI: A1G_06260
RRA: RPO_06320
RRC: RPL_06305
RRH: RPM_06290
RRB: RPN_00730
RRN: RPJ_06265
RRP: RPK_06245
RMS: RMA_1165(phbC)
RMI: RMB_02215
RPK: RPR_03310
RPH: RSA_06295
RMO: MCI_02930
RRE: MCC_06865
RMC: RMONA_01255(phbC_1) RMONA_03090(rutD_1)
RTL: H6P87_01170(rutD) H6P87_01289(phaC)
REN: EF513_05840(phaC)
MLO: mlr0937
MHUA: MCHK_2670(phaC)
MJR: EB229_21015(phaC)
MESR: FGU64_02120(phaC)
MES: Meso_1925
AMIH: CO731_03689(phbC)
RPOD: E0E05_09810(phaC)
NKI: KW403_00815(phaC)
ORM: HTY61_04635(phaC)
SME: SMc00296(phbC)
SMX: SM11_chr1674(phbC)
SMI: BN406_01467(phbC)
SMEL: SM2011_c00296(phbC)
SMER: DU99_09455
SMD: Smed_1456
RHI: NGR_c14000(phbC2) NGR_c34290(phbC1)
SFH: SFHH103_01298(phbC) SFHH103_02565(phbC1)
SFD: USDA257_c16650(phaC1) USDA257_c35930(phbC)
SIX: BSY16_1253(phaC)
EAD: OV14_2642(phbC2)
EMX: FKV68_08330(phaC)
ATU: Atu1604(phbC)
ARA: Arad_2158(phbC)
AGR: AGROH133_06421(phbC)
ATF: Ach5_15360(phbC)
AVI: Avi_2276(phbC)
AGC: BSY240_791(phaC)
ARO: B0909_04985(phaC)
AGT: EYD00_06075(phaC)
ALF: CFBP5473_09650(phaC)
RET: RHE_CH01875(phbC)
REC: RHECIAT_CH0001961(phbC)
REL: REMIM1_CH01928(phbC)
REP: IE4803_CH01909(phbC)
REI: IE4771_CH01985(phbC)
RLE: RL2094(phaC) pRL100105
RLG: Rleg_1736
RIR: BN877_I1569(phbC)
RPUS: CFBP5875_06630(phaC)
RHL: LPU83_1931(phaC)
RGA: RGR602_CH01748(phbC)
RHN: AMJ98_CH01931(phbC)
RPHA: AMC79_CH02004(phbC)
RHX: AMK02_CH01940(phbC)
RHK: Kim5_CH02012(phbC)
REZ: AMJ99_CH02009(phbC)
RJG: CCGE525_09510(phaC)
RGR: FZ934_05720(phaC)
RAD: CO657_07835(phaC)
ROY: G3A56_03115(phaC)
RII: FFM53_002700(phaC) FFM53_032770(phaC)
RHID: FFM81_011655(phaC) FFM81_032175(phaC)
RBQ: J2J99_09720(phaC)
RLN: J0663_18390(phaC) J0663_30650(phaC)
RBAN: J2J98_09495(phaC)
RRG: J3P73_11145(phaC)
RLS: HB780_15075(phaC)
NEN: NCHU2750_15580(phbC)
RHT: NT26_2023(phbC)
ABAW: D5400_13615(phaC)
PDES: FE840_012635(phaC)
KAI: K32_22100
BJA: bll4360(bll4360) bll6073(phbC) blr2885(blr2885) blr3732(phbC)
BRA: BRADO3568(phbC) BRADO5310
BRS: S23_22030(phbC) S23_39220(phbC) S23_51300
RPA: RPA2501(phbC) RPA4243(phaC)
RBK: E0H22_13220(phaC)
NWI: Nwi_1650
NHA: Nham_2312
OCA: OCAR_4862(phbC) OCAR_6012
OCG: OCA5_c20130(phbC) OCA5_c30890(phaC2)
OCO: OCA4_c20120(phbC) OCA4_c30370(phaC2)
VGO: GJW-30_1_02915(phbC_1) GJW-30_1_03921(phbC_2)
TRB: HB776_08645(phaC)
BOS: BSY19_144 BSY19_2259(phaC)
AZC: AZC_1845(phbC) AZC_4082
STAR: G3545_05570(phaC)
LNE: FZC33_33510(phaC)
ANC: GBB76_02365(phaC)
APRA: G3A50_01125(phaC)
MEA: Mex_1p3304(phaC)
MDI: METDI0292 METDI3869(phaC)
MEX: Mext_3093
MCH: Mchl_3413
MPO: Mpop_3286
META: Y590_15055
MAQU: Maq22A_c06395(phaC)
MMES: MMSR116_03435(phaC) MMSR116_26980(phaC)
MIND: mvi_44950(phbC)
MICO: GDR74_09975(phaC)
BBAR: RHAL1_01840(phaC)
FIL: BN1229_v1_0512(phbC) BN1229_v1_1862(phaC)
FIY: BN1229_v1_0515(phbC) BN1229_v1_1865(phaC)
MCG: GL4_2011
BLAG: BLTE_19420 BLTE_30630(phbC)
PLEO: OHA_1_01021(phaC)
HDI: HDIA_1599(phbC_1) HDIA_2775(phbC_2)
AALA: IGS74_15215(phaC)
AALM: LUX29_17155(phaC)
AUB: LXB15_07975(phaC)
NOH: G5V57_30860(phaC)
PSF: PSE_3537
LABT: FIU93_22105(phbC)
LIZ: LGH83_02175(phaC)
CCR: CC_1380
CSE: Cseg_1680
CAUF: CSW63_13855(phaC)
CAUL: KCG34_03475(phaC)
PZU: PHZ_c1646(phbC) PHZ_p0111(phbC)
BDM: EQG53_14060(phaC)
BRF: E4M01_07775(phaC)
BREV: E7T10_09620(phaC)
BMED: GYM46_15525(phaC)
BVY: NCTC9239_01227(phbC)
BND: KWG56_05100(phaC)
BPON: IFE19_10115(phaC)
BGOE: IFJ75_05710(phaC)
BVIT: JIP62_03045(phaC)
TSV: DSM104635_02114(phbC)
SIL: SPO0112 SPO1292(phaC)
RUT: FIU92_10360(phbC1) FIU92_13495(phbC2)
JAN: Jann_1117
RDE: RD1_1888(phaC)
RLI: RLO149_c009850(phbC)
RPON: G3256_12490(phaC) G3256_13335(phaC)
DSH: Dshi_0428(phaC) Dshi_2233(phbC)
PGA: PGA1_c20930(phaC)
PGL: PGA2_c19770(phaC)
PGD: Gal_01310
PHP: PhaeoP97_01823(phaC)
PPIC: PhaeoP14_01903(phaC)
PHQ: D1820_05920(phaC)
OAT: OAN307_c15970(phbC)
OAR: OA238_c06940(phbC)
OTM: OSB_10100(phbC)
OCT: FTO60_04825(phaC)
LAQU: R2C4_10890(phaC)
MALG: MALG_02221
SPSE: SULPSESMR1_00795(phbC)
SPOT: G6548_06910(phaC)
SMED: JNX03_07440(phaC)
RID: RIdsm_00124(phbC_1) RIdsm_03326(phbC_2)
ROM: EI983_05990(phaC)
ROH: FIU89_12880(phbC)
AHT: ANTHELSMS3_04404(phbC)
OCD: FHY55_15690(phaC)
MARU: FIU81_11995(phbC)
ROT: FIV09_03940(phbC1) FIV09_07015(phbC2)
MALU: KU6B_04040(phbC1) KU6B_38740
TMD: KUV46_13805(phaC)
RSP: RSP_0382 RSP_1257(phbC)
RCP: RCAP_rcc00746(phbC)
PARS: DRW48_11105(phaC)
PARR: EOJ32_08010(phaC)
PKD: F8A10_14875(phaC)
PLIA: E4191_11140(phaC) E4191_23005(phaC)
PMAU: CP157_02029(phaC)
PTP: RCA23_c27880(phaC)
LVS: LOKVESSMR4R_00899(phbC)
SALO: EF888_19720(phaC)
SEDI: EBB79_13590(phaC)
BOO: E2K80_01620(phaC)
LIT: FPZ52_08165(phaC)
PSHQ: F3W81_08750(phaC)
PALW: PSAL_013980(phaC)
PPAF: I8N54_07425(phaC)
CACT: HZ995_00620(phaC)
FAQ: G5B39_08510(phaC)
HYT: HXX25_05020(phaC)
HBA: Hbal_1867
NGF: FRF71_04145(phaC)
SAL: Sala_0505
SPHP: LH20_01510
SMAZ: LH19_02695
SGI: SGRAN_0652(phbC) SGRAN_1139 SGRAN_1295(phbC2)
SPHX: E5675_14515(phaC)
SPHU: SPPYR_2640(phbC)
SPHA: D3Y57_14015(phaC)
SCHY: GVO57_03030(phaC)
SJP: SJA_C1-16970(phbC) SJA_C1-32560(phbC)
SPHR: BSY17_1842(phaC) BSY17_262
POQ: KZX46_13645(phaC)
AAY: WYH_00777(phbC_1) WYH_01560(phbC_2) WYH_02662(phbC_3) WYH_02741(phbC_4)
AMX: AM2010_72
ANH: A6F65_02491(phbC)
ADO: A6F68_01218(phbC_1) A6F68_02008(phbC_2)
TFV: IDJ81_13780(phaC)
ERF: FIU90_11220(phbC1) FIU90_15160(phbC2)
GDI: GDI3304(phbC)
GDJ: Gdia_3066
AZL: AZL_023140(phaC) AZL_a02630(phaC)
ABS: AZOBR_100383(phbC) AZOBR_p440016(phbC)
RCE: RC1_0541(phaC) RC1_1308(phbC)
MGRY: MSR1_01750(phbC3) MSR1_04780(phbC1) MSR1_23600(phbC2)
MAGX: XM1_1599(phbC) XM1_4432
TMO: TMO_0155(phbC) TMO_1945(phbC) TMO_3478(phbC)
DVN: HQ394_11755(phaC)
MAGQ: MGMAQ_1758(phbC) MGMAQ_2991
MGM: Mmc1_1170
MAI: MICA_1031(phaC) MICA_961
BAN: BA_1331(phaC)
BAR: GBAA_1331(phaC)
BAT: BAS1231
BAH: BAMEG_3265(phaC)
BAI: BAA_1398(phaC)
BANT: A16_58035
BANR: A16R_13940
BANS: BAPAT_1249
BANV: DJ46_154(phaC)
BCE: BC1318
BCA: BCE_1430(phaC)
BCZ: BCE33L1210(phaC)
BCR: BCAH187_A1471(phaC)
BCB: BCB4264_A1369(phaC)
BCU: BCAH820_1406(phaC)
BCG: BCG9842_B3975(phaC)
BCQ: BCQ_1390(phaC)
BCX: BCA_1369(phaC)
BAL: BACI_c13510(phaC)
BNC: BCN_1291
BCF: bcf_06670
BCER: BCK_01800
BTK: BT9727_1208(phaC)
BTL: BALH_1180
BTB: BMB171_C1161(phaC)
BTT: HD73_1547
BTHI: BTK_07880
BTC: CT43_CH1248(phaC)
BTM: MC28_0546
BTG: BTB_c13610(phbC)
BTI: BTG_14155
BTW: BF38_2537(phaC)
BWW: bwei_3691(phaC)
BMYO: BG05_4581(phaC)
BMYC: DJ92_3964(phaC)
BTRO: FJR70_28860(phaC)
BMOB: MLA2C4_06995(phaC)
BNT: GSN03_06680(phaC)
BACO: OXB_2253
BMQ: BMQ_1231(phaC)
BMD: BMD_1216(phaC)
BMH: BMWSH_4007(phaC)
BMEG: BG04_3531(phaC)
PARH: I5S86_03185(phaC) I5S86_03195(phaC)
BPF: BpOF4_07445(phaC)
BKW: BkAM31D_11395(phbC)
PASA: BAOM_0804(phbC)
BCHS: JNE38_08265(phaC)
ASOC: CB4_03453(phbC)
ATHE: K3F53_05285(phaC)
BTS: Btus_1591
SPAE: E2C16_04275(phaC)
PANC: E2636_08785(phaC)
CRS: FQB35_11700(phaC)
CPRF: K7H06_19355(phaC)
FAA: HMPREF0389_01601(phaC)
HCV: FTV88_0565(phaC)
AMIC: Ami3637_10715(phaC)
APR: Apre_0114
AMEI: LV469_08695(phaC)
PHAR: NCTC13077_00524(phbC)
MFJ: MFLOJ_21390(phaC1)
MCOO: MCOO_45090(phaC1)
MBRD: MBRA_28240(phaC1)
MCHT: MCHIJ_39350(phbC)
MIJ: MINS_41560(phaC1)
MAUB: MAUB_36380(phaC1)
MPHU: MPHO_07550 MPHO_33910(phaC1)
MMAT: MMAGJ_21960(phaC1)
MAB: MAB_2917
MABB: MASS_2856
MCHE: BB28_14615
MSTE: MSTE_02881
MSAL: DSM43276_02636(phbC)
NFA: NFA_45720
NFR: ERS450000_05361(phbC)
NAD: NCTC11293_02090(phbC_1) NCTC11293_03559(phbC_2) NCTC11293_05855(phbC_3)
RER: RER_48680
REY: O5Y_23075
REQ: REQ_12750
RCR: NCTC10994_02014(phbC)
GOR: KTR9_4566
GOM: D7316_03122(phaC_2)
LMOI: VV02_19950
NCA: Noca_3995
NDK: I601_0534(phbC_1) I601_2077(phbC_2)
NAQU: ENKNEFLB_00936(phaC_1) ENKNEFLB_03514(phaC_2)
TCU: Tcur_1667
MMAR: MODMU_2205 MODMU_2461(phaA) MODMU_4006(phaA)
AMD: AMED_6470(phbC) AMED_7913
AMM: AMES_6376(phbC) AMES_7795
AMZ: B737_6376(phbC) B737_7795
AOI: AORI_6733(phbC)
AMYY: YIM_05875(phbC)
AORI: SD37_06965
PSEA: WY02_28065
SESP: BN6_33650
RMAR: GBA65_16595(phaC) GBA65_16620(phaC)
CWO: Cwoe_5780
SYN: slr1830(phbC)
SYZ: MYO_18620(phbC)
SYY: SYNGTS_0856(phbC)
SYT: SYNGTI_0856(phbC)
SYS: SYNPCCN_0855(phbC)
SYQ: SYNPCCP_0855(phbC)
SYJ: D082_28610(phaC)
MAR: MAE_50030(phaC)
MPK: VL20_2945
MVZ: myaer102_23270(phaC)
ARP: NIES39_Q00060(phaC)
OXY: HCG48_12780(phaC)
LFS: HFV01_24860(phaC)
AFLO: HEQ12_10825(phaC)
RCA: Rcas_0105
CAU: Caur_3263
CAG: Cagg_0629
AMUC: Pan181_30350(phbC_1) Pan181_30510(phbC_2)
AGV: OJF2_37050(phbC)
LIL: LA_3672
LIE: LIF_A2949
LIC: LIC_10546
LIS: LIL_10551
GAH: GAH_01709
HMA: rrnAC2886(phaC)
HHI: HAH_0154(phaC)
HALJ: G9465_03175(phaC)
HSIN: KDQ40_13085(phaC)
NMO: Nmlp_3925(phaC)
NSAL: HWV07_12325(phaC)
HUT: Huta_2163
HTI: HTIA_2073(phaC)
HALA: Hrd1104_11740(phaC)
HMU: Hmuk_0991
HALZ: E5139_08115(phaC)
HALL: LC1Hm_0239
HAZP: GBQ70_08110(phaC)
HSN: DV733_05230(phaC)
HRR: HZS55_01235(phaC)
HPEL: HZS54_07785(phaC)
HLT: I7X12_11500(phaC)
HWA: HQ_2310A(phaC)
HWC: Hqrw_2555(phaC)
HME: HFX_2678(phaC1) HFX_5221(phaC) HFX_6061(phaC2) HFX_6429(phaC3)
HAQ: DU484_07805(phaC) DU484_10200(phaC)
HAJ: DU500_07970(phaC) DU500_10445(phaC)
HAER: DU502_07620(phaC)
HRA: EI982_06425(phaC)
HTU: Htur_2455
HJT: DVR14_15260(phaC)
HALY: HYG82_07130(phaC)
HSAL: JMJ58_16570(phaC)
HLO: J0X27_01880(phaC)
HAKZ: J0X25_00505(phaC)
NAT: NJ7G_1490
NVR: FEJ81_06590(phaC)
NPL: FGF80_04780(phaC)
SALI: L593_00965
NBG: DV706_11595(phaC)
NAS: GCU68_00540(phaC)
MELU: MTLP_10110(phaC) MTLP_10120(phbC)
NMR: Nmar_0991
NIW: Nisw_08490(phaC)
NIP: NsoK4_02830(phaC)
NCT: NMSP_0561
NGA: Ngar_c20300(phbC1) Ngar_c20680(phaC1) Ngar_c25870(phaC2) Ngar_c32720(phbC4)
NVN: NVIE_003010(phaC)
NEV: NTE_01626
TAA: NMY3_01645(phbC_1) NMY3_02458(phbC_2) NMY3_02866
NFN: NFRAN_1534(phbC) NFRAN_3039(phbC)
NCV: NCAV_0513(phbC) NCAV_1529(phaC)
NDV: NDEV_1356(phbC)
 » show all
Reference
1  [PMID:2078525]
  Authors
Anderson AJ, Haywood GW, Dawes EA.
  Title
Biosynthesis and composition of bacterial poly(hydroxyalkanoates).
  Journal
Int J Biol Macromol 12:102-5 (1990)
DOI:10.1016/0141-8130(90)90060-n
Reference
2  [PMID:7957260]
  Authors
Liebergesell M, Sonomoto K, Madkour M, Mayer F, Steinbuchel A.
  Title
Purification and characterization of the poly(hydroxyalkanoic acid) synthase from Chromatium vinosum and localization of the enzyme at the surface of poly(hydroxyalkanoic acid) granules.
  Journal
Eur J Biochem 226:71-80 (1994)
DOI:10.1111/j.1432-1033.1994.tb20027.x
Reference
3  [PMID:9888824]
  Authors
Muh U, Sinskey AJ, Kirby DP, Lane WS, Stubbe J.
  Title
PHA synthase from chromatium vinosum: cysteine 149 is involved in covalent catalysis.
  Journal
Biochemistry 38:826-37 (1999)
DOI:10.1021/bi9818319
Reference
4  [PMID:10880359]
  Authors
Ren Q, De Roo G, Kessler B, Witholt B.
  Title
Recovery of active medium-chain-length-poly-3-hydroxyalkanoate polymerase from inactive inclusion bodies using ion-exchange resin.
  Journal
Biochem J 349:599-604 (2000)
DOI:10.1042/0264-6021:3490599
Reference
5  [PMID:11170423]
  Authors
Jia Y, Yuan W, Wodzinska J, Park C, Sinskey AJ, Stubbe J.
  Title
Mechanistic studies on class I polyhydroxybutyrate (PHB) synthase from Ralstonia eutropha: class I and III synthases share a similar catalytic mechanism.
  Journal
Biochemistry 40:1011-9 (2001)
DOI:10.1021/bi002219w
Reference
6  [PMID:28884324]
  Authors
Zou H, Shi M, Zhang T, Li L, Li L, Xian M.
  Title
Natural and engineered polyhydroxyalkanoate (PHA) synthase: key enzyme in biopolyester production.
  Journal
Appl Microbiol Biotechnol 101:7417-7426 (2017)
DOI:10.1007/s00253-017-8485-0
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.304
IUBMB Enzyme Nomenclature: 2.3.1.304
ExPASy - ENZYME nomenclature database: 2.3.1.304
BRENDA, the Enzyme Database: 2.3.1.304

DBGET integrated database retrieval system