KEGG   ENZYME: 2.4.1.251
Entry
EC 2.4.1.251                Enzyme                                 
Name
GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol 4-beta-mannosyltransferase;
GumI
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
GDP-mannose:GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol 4-beta-mannosyltransferase
Reaction(IUBMB)
GDP-mannose + GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol = GDP + D-Man-beta-(1->4)- GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol [RN:R09734]
Reaction(KEGG)
R09734
Substrate
GDP-mannose [CPD:C00096];
GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol
Product
GDP [CPD:C00035];
D-Man-beta-(1->4)- GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol
Comment
The enzyme is involved in the biosynthesis of the exopolysaccharide xanthan.
History
EC 2.4.1.251 created 2011
Orthology
K13658  beta-1,4-mannosyltransferase
Genes
XCCXCC2447(gumI)
XCBXC_1665
XCAxcc-b100_1719(gumI)
XCPXCR_2760(gumI)
XCVXCV2780(gumI)
XAXXACM_2560(gumI)
XACXAC2578(gumI)
XCIXCAW_02259(gumI)
XCTJ151_02759
XCJJ158_02746
XCUJ159_02744
XCNJ169_02756
XCWJ162_02748
XCRJ163_02743
XCMJ164_02745
XCFJ172_02750
XFUXFF4834R_chr26150(gumI)
XAOXAC29_13130
XOMXOO3012(XOO3012)
XOOXOO3172(gumI)
XOPPXO_01399(gumI)
XOYAZ54_08005
XORXOC_1874(gumI)
XOZBE73_08795
XSASB85_04170
XTNFD63_08020
XFRBER92_06075
XVEBJD12_03920
XPEBJD13_03585
XHRXJ27_06770
XGABI317_09565
XPHXppCFBP6546_19505(XppCFBP6546P_19505)
XVAC7V42_09280
XANAC801_09280
XARXB05_07780
XHYFZ025_16435
XCZEBN15_09445
XEUXSP_002561
XHDLMG31886_17100(gumI)
XPRMUG10_18760
PSDDSC_06250
PATPatl_1086 Patl_1188
AMCMADE_1013195
AMBAMBAS45_07930
AMKAMBLS11_07415
ALRDS731_04805
SALMD0Y50_03605
SALKFBQ74_13660
SMAAIT774_13285
CJACJA_0616(gt4J-1)
CEBB0D95_08995
CELLCBR65_10410
CEKD0B88_17295
SPOIIMCC21906_00972
TTPE6P07_03940
HVNEI420_13500
BUGBC1001_0542
BGFBC1003_0568
BUQAC233_03015
BPXBUPH_04429
PGPCUJ91_03130
PCJCUJ87_02925
AKATKWG_23340
AMIMMIM_c37670
ODIODI_R3712
RGERGE_10800
AONDEH84_14380
APETToN1_34820
RBHB4966_11290
AZAAZKH_0950(gumI)
AZIAzCIB_0829
ZPAC3497_10380
GEBGM18_1580
RVARvan_0831
AUAM673_05000
ACUTMRB58_07595
RSHRsph17029_3140
RHPLPB142_08265
LVSLOKVESSMR4R_02794
TAWEI545_12650
SPAUDRN02_015730
ACRAcry_0590
AMVACMV_06650
RCERC1_2571
DVNHQ394_05730
ECOGFIV45_07895
BWHA9C19_01635
PMSKNP414_06726
PMQPM3016_6348
PMWB2K_32095
PBJVN24_15585
PXLBS614_10335
COHEAV92_15450
COHNKCTCHS21_12090
CPATCLPA_c06550
CPAECPAST_c06550
TMRTmar_0648
THEPDYI95_003090
MHOLK3U96_05175
MRHMycrhN_1282
MAICMAIC_50300(gumI)
MARZMARA_13060
MPOFMPOR_19800(gumI)
MMUCC1S78_013825
CGJAR0_02305
CGXSB89_02060
SPUNBFF78_36155
PSICJ4E96_00875 J4E96_16465
LEIFHF024_16555
CMICMM_0831(wcoM)
CMSCMS2390(kanE)
CMCCMN_00790(wcoM)
CMHVO01_12185
CCAPAES38_03680
CZHH9X71_03745
CPHAFGI33_09195
CCAFFGD68_06200
MIMAKG07_08690
MIOAOA12_03795
MIPAXH82_09245 AXH82_12460
MIHBJP65_06430
MICRBMW26_02580 BMW26_13210 BMW26_13230
MFOLDXT68_02665
MOOBWL13_00215(gumI)
MLVCVS47_00186(gumI_1) CVS47_00496(gumI_2)
MPRTET475_11865
MSEDE3O41_09820
MRNK8F61_11275 K8F61_17475
MICSC1N74_13670
RTNA6122_0256 A6122_1742
RRYC1O28_14675
RIAC7V51_11055
RFSC1I64_18635
RTEGSU10_13770
FRPAX769_19860
AGYATC03_05605 ATC03_05660
CARTPA27867_3179
SALCC2138_11690
SALDFVA74_02115 FVA74_08010
LYDD7I47_12135
LYKFLP23_09675
LTREVS81_09975
AREAL755_06105
ARYATC04_10850
ALXLVQ62_07905
XYLET495_12905
XYAET471_05205
CETB8281_08180
CFLCfla_0743
CFICelf_3034
CGACelgi_1082
CEZCBP52_08085 CBP52_17135
CELZE5225_13605
CEJGC089_14220
CELHGXP71_00835
CPALF1D97_06705
CDONKKR89_03690 KKR89_04390
CWANKG103_04690
CFENKG102_03055
ICAIntca_1140
PBOPACID_07860
AACIASQ49_00880
MIKFOE78_04005
AERAERYTH_15490
AEZC3E78_02035
AEFGEV26_02180
NMLNamu_4450
MMARMODMU_0445
KRAKrad_3679
SAQSare_4490
EKEEK0264_07580
JTLM6D93_04995 M6D93_16465
SYNPSyn7502_03077
LEPLepto7376_0846
HHGXM38_030110(gumI) XM38_039170
HAOPCC7418_2790
TERTery_4124
MICMic7113_0578
GEIGEI7407_2188
MPROBJP34_07710
NOSNos7107_3403
NOPNos7524_1911
NONNOS3756_45300
NOECLI64_13390 CLI64_19825
NAZAazo_4909
ACYAnacy_3785
CALOCal7507_2135
CALTCal6303_3317
CTHEChro_2379
HAUHaur_0821
STISthe_3491
PBSPlabr_4177
GESVT84_04200(mshA_2)
GMSSOIL9_83950
ADINH7849_03570
BVSBARVI_07010
ARBA9P82_05935
PSNPedsa_1026
SHGSph21_1799 Sph21_2071
OLIFKG96_07220
EVIEchvi_4232
ESTDN752_05615
ECHIFKX85_19550
SRDSD10_21320
SMONAWR27_19960
RHOZGXP67_30610
RSIRunsl_1739
NOBCW736_09245
TCHCHITON_0516
TPAFA3L08_02315
HSUHLASF_1523
HSFHLASA_1510
HLMDV707_16085
SRUBC2R22_14670 C2R22_14795 C2R22_15395
NATNJ7G_3590
 » show all
Reference
1  [PMID:9537354]
  Authors
Katzen F, Ferreiro DU, Oddo CG, Ielmini MV, Becker A, Puhler A, Ielpi L
  Title
Xanthomonas campestris pv. campestris gum mutants: effects on xanthan biosynthesis and plant virulence.
  Journal
J Bacteriol 180:1607-17 (1998)
DOI:10.1128/JB.180.7.1607-1617.1998
  Sequence
[xcc:XCC2447]
Reference
2  [PMID:7683019]
  Authors
Ielpi L, Couso RO, Dankert MA
  Title
Sequential assembly and polymerization of the polyprenol-linked pentasaccharide repeating unit of the xanthan polysaccharide in Xanthomonas campestris.
  Journal
J Bacteriol 175:2490-500 (1993)
DOI:10.1128/JB.175.9.2490-2500.1993
Reference
3  [PMID:18854951]
  Authors
Kim SY, Kim JG, Lee BM, Cho JY
  Title
Mutational analysis of the gum gene cluster required for xanthan biosynthesis in  Xanthomonas oryzae pv oryzae.
  Journal
Biotechnol Lett 31:265-70 (2009)
DOI:10.1007/s10529-008-9858-3
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.251
IUBMB Enzyme Nomenclature: 2.4.1.251
ExPASy - ENZYME nomenclature database: 2.4.1.251
BRENDA, the Enzyme Database: 2.4.1.251

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