KEGG   ENZYME: 2.4.1.306
Entry
EC 2.4.1.306                Enzyme                                 

Name
UDP-GalNAc:alpha-D-GalNAc-diphosphoundecaprenol alpha-1,3-N-acetylgalactosaminyltransferase;
WbnH
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
UDP-N-acetyl-alpha-D-galactosamine:N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol alpha-1,3-N-acetyl-D-galactosyltransferase
Reaction(IUBMB)
UDP-N-acetyl-alpha-D-galactosamine + N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol = UDP + alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol [RN:R10435]
Reaction(KEGG)
R10435
Substrate
UDP-N-acetyl-alpha-D-galactosamine [CPD:C00203];
N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol [CPD:C20620]
Product
UDP [CPD:C00015];
alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol [CPD:C20621]
Comment
The enzyme is involved in the the biosynthesis of the O-polysaccharide repeating unit of Escherichia coli serotype O86.
History
EC 2.4.1.306 created 2013
Orthology
K21365  O86/O127-antigen biosynthesis alpha-1,3-N-acetylgalactosaminyltransferase
Genes
ECG: E2348C_2181(wbiN)
CYO: CD187_08950
Reference
1  [PMID:16630548]
  Authors
Yi W, Yao Q, Zhang Y, Motari E, Lin S, Wang PG
  Title
The wbnH gene of Escherichia coli O86:H2 encodes an alpha-1,3-N-acetylgalactosaminyl transferase involved in the O-repeating unit biosynthesis.
  Journal
Biochem Biophys Res Commun 344:631-9 (2006)
DOI:10.1016/j.bbrc.2006.03.181
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.306
IUBMB Enzyme Nomenclature: 2.4.1.306
ExPASy - ENZYME nomenclature database: 2.4.1.306
BRENDA, the Enzyme Database: 2.4.1.306

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