KEGG   ENZYME: 2.5.1.131
Entry
EC 2.5.1.131                Enzyme                                 
Name
(4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase;
MfnF
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
Sysname
[5-(aminomethyl)furan-3-yl]methyl-diphosphate:gamma-L-glutamyltyramine [5-(aminomethyl)furan-3-yl]methyltransferase
Reaction(IUBMB)
[5-(aminomethyl)furan-3-yl]methyl diphosphate + gamma-L-glutamyltyramine = (4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine + diphosphate [RN:R11040]
Reaction(KEGG)
R11040
Substrate
[5-(aminomethyl)furan-3-yl]methyl diphosphate [CPD:C21069];
gamma-L-glutamyltyramine [CPD:C20926]
Product
(4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine [CPD:C21070];
diphosphate [CPD:C00013]
Comment
The enzyme, isolated from the archaeon Methanocaldococcus jannaschii, participates in the biosynthesis of the methanofuran cofactor.
History
EC 2.5.1.131 created 2015
Pathway
ec00680  Methane metabolism
ec01100  Metabolic pathways
Orthology
K07072  (4-(4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl)furan-2-yl)methanamine synthase
Genes
MCAMCA2869
METUGNH96_03500
MMTMetme_2271
MDNJT25_019365
MDHAYM39_08570
MKOMKLM6_1784
METLU737_14790
MPADKEF85_11445
MELLIVG45_03960
MAHMEALZ_2434
MBUREQU24_09085
MPSYCEK71_02035
MMAIsS8_3387
MMOBF6R98_18220
MEINmethR_P1411
MOZMoryE10_04110
MISZMishRS11D_40190
MESLKKZ03_09115
MEJQ7A_51
MECQ7C_1778
MPINLGT42_002825
BLEPAL038_14875
NOCNoc_0256
NHLNhal_3882
NWANwat_0354
NWRE3U44_04645
NTTTAO_1760
TSYTHSYN_31750
NTGNSCAC_0078
TBOGLT988_22430
SEDSAAY24_01685
COXE0W60_31980
BUGBC1001_3968
BGFBC1003_5434
BYIBYI23_B014260
BUEBRPE67_BCDS01230
BUQAC233_22135
BPHBphy_5937 Bphy_6501
BGEBC1002_3203
BCAIK788_0001565 K788_0007398
PSPWBJG93_19495
PARABTO02_23545
PHSC2L64_21770 C2L64_38205
PTERC2L65_26225 C2L65_34200
PGPCUJ91_21395
PCJCUJ87_23525
PGISI6I06_22570
VAPVapar_3070
VPDVAPA_1c31350
MPTMpe_A2620
METPC1M51_15040
RGERGE_40350
LCHLcho_3139
AONDEH84_18950
METRBSY238_3385
MFAMfla_1649
MMBMmol_1334
MEHM301_1543
MEIMsip34_1492
MEPMPQ_1555
MBACBN1209_0775
MEUACJ67_07440
MPAUZMTM_11930
SPLBSFPGR_25900
AZAAZKH_p0262
AZDCDA09_11450
THUAC731_004890
THKCCZ27_13205
DDZDSYM_25750
MCIMesci_4265
MESWA9K65_023645
MESMEJ066_29745
PHTBLM14_23815
RGARGR602_PC01573
XAUXaut_1791
SNOSnov_0745
STARG3545_09805
LNEFZC33_09360
ANCGBB76_00725
APRAG3A50_16470
APOLK9D25_20215
MEAMex_1p1768
MDIMETDI2520
MEXMext_1836
MCHMchl_2171
MPOMpop_1787
MZAB2G69_16840
MRDMrad2831_0965
METM446_5788
MNOMnod_6009
MORMOC_1181
METAY590_08795
MAQUMaq22A_c23990
MPHYMCBMB27_00560
MEEDA075_05755
METDC0214_10550
METXA3862_25750
METIDK427_13880
MMESMMSR116_26060
MTEADK419_10820
MINDmvi_43420
MOGMMB17_19990
MSLMsil_2392
MTUNMTUNDRAET4_2728
MLGCWB41_06070
HDNHden_1472
HDTHYPDE_31283
HMCHYPMC_1622
HNIW911_13200
FILBN1229_v1_0581
FIYBN1229_v1_0583
MCGGL4_1781
METGHT051_10205
MSCBN69_1050
MBRYB1812_17880
MROSEHO51_11435
MHEYH2LOC_014915
MPARF7D14_11830
MTWCQW49_13855
PLEOOHA_1_01030
HDIHDIA_2317
AALAIGS74_05755
AALMLUX29_06510
AUZSa4125_38580
AUBLXB15_00950
GBEGbCGDNIH1_0768
GBHGbCGDNIH2_0768
GBCGbCGDNIH3_0768
GBSGbCGDNIH4_0768
ALIAZOLI_p10883
ABSAZOBR_p270077
ABQABAZ39_25500
ATIAL072_21130
AZTTSH58p_01235
AZMDM194_17070
AOZHUE56_08890
FWADCMF_03945
HASHalsa_0952
RBARB6209
PSLPsta_3592
PIRVN12_07525
RULUC8_21020
RMLFF011L_17940
MFFMFFC18_12350
ROLCA51_35260
AHELQ31a_27960
LCREPla8534_39480
AAGGETAA8_35440
BVOPan97_22170
RLCK227x_21220
LPAVPLANPX_2815
AMUCPan181_27100
PNDPla175_21260
AMOBHG15A2_27270
PLMPlim_0257
PEHSpb1_10160
PBSPlabr_4664
PLSVT03_12545
PLHVT85_05495
FMRFuma_00148
GMRGmarT_45470
GIMF1728_22320
GPNPan110_43590
MRIMal4_12170
SDYNMal52_29040
PLONPla110_00240
GESVT84_31915
GOGC1280_01515
GMSSOIL9_58910
TIMGMBLW1_24080
LRSPX52LOC_03569
FTJFTUN_4763
ULIETAA1_22110
TSPHKIH39_02590
IPAIsop_3533
SACISinac_1216
PBORBSF38_00157
AGVOJF2_59350
AMOAnamo_1254
PJOLK449_18550
OCYOSSY52_02120
MOXDAMO_2658
MJAMJ_0840
MFEMefer_0932
MVUMetvu_0143
MFSMFS40622_1321
MIFMetin_1065
MJHJH146_1062
MESGMLAUSG7_0359(mfnF)
MESAMLASG1_1538(mfnF)
MIGMetig_1150
MMPMMP0072
MMQMmarC5_1605
MMXMmarC6_0876
MMZMmarC7_1071
MMDGYY_00365
MMAKMMKA1_00750
MMAOMMOS7_00990
MMADMMJJ_10220
MAEMaeo_0623
MVNMevan_1085
MVOMvol_1437
MOKMetok_0884
METFCFE53_00055
MTHMTH_834
MMGMTBMA_c12320
MWOMWSIV6_1211(mfnF)
MTEEMTTB_05410
METCMTCT_0748
METEtca_00801
METZMETMT2_0907
METKFVF72_07370
MTHMFZP57_05750
METJFZP68_00455
MSTMsp_0386
METBAW729_05140
MRUmru_1695
MSIMsm_0851
MEBAbm4_0505
MMILsm9_1778
MEYETL18_07945
MOLYLM1_1163
MAROMarbSA_18750
METVK4897_07225
MELMetbo_1948
MEWMSWAN_0671
METHMBMB1_0691
MFCBRM9_1504
MFIDSM1535_2198
MCUBMCBB_0702(mfnF)
MSUBBK009_01675
METNBK008_09250
METTCIT01_01985
METOCIT02_03315
MEMEHYG87_03500
MFVMfer_0209
MKAMK0113
AFUAF_0479
AFGAFULGI_00004870
AVEArcve_1963
ASTAsulf_00362
FPLFerp_0819
GACGACE_1625
GAHGAH_00950
MBAMbar_A3437
MBYMSBRM_1198
MBWMSBRW_1296
MBARMSBR2_1212
MBAKMSBR3_1317
MACMA_1474
MMAMM_2511
MMAZMmTuc01_2560
MMJMSMAS_2192
MMACMSMAC_2262
MVCMSVAZ_1447
MEKMSKOL_1392
MLSMSLAZ_0911
METMMSMTP_0946
MEFMSWH1_1889
MEQMSWHS_3184
MSJMSSAC_1476
MSZMSSIH_1483
MSWMSSIT_1539
MTHRMSTHT_0226
MTHEMSTHC_0506
MHORMSHOH_2801
MFZAOB57_001290
MBUMbur_1316
MMETMCMEM_1763
MELOJ7W08_07845
MMHMmah_1620
MHAZBHR79_05625
MEVMetev_0254
MZHMzhil_1620
MPYMpsy_2545
MZIHWN40_09630
MHZMetho_0939
MTPMthe_0173
MCJMCON_2321
MHIMhar_2357
MHUMhun_0572
MRTJKHC33_08695
MLAMlab_0269
MEMMemar_1383
MBGBN140_1325
MEMAMMAB1_1686
MCHKMchiMG62_15800
MPIMpet_1052
MBNMboo_0921
MFOMetfor_1880
MPLMpal_0580
MPDMCP_1325
MEZMtc_1030
RCIRCIX2219
MELUMTLP_02160
BARBAOA66_0933
 » show all
Reference
1  [PMID:26100040]
  Authors
Wang Y, Xu H, Jones MK, White RH
  Title
Identification of the Final Two Genes Functioning in Methanofuran Biosynthesis in Methanocaldococcus jannaschii.
  Journal
J Bacteriol 197:2850-8 (2015)
DOI:10.1128/JB.00401-15
  Sequence
[mja:MJ_0840]
Other DBs
ExplorEnz - The Enzyme Database: 2.5.1.131
IUBMB Enzyme Nomenclature: 2.5.1.131
ExPASy - ENZYME nomenclature database: 2.5.1.131
BRENDA, the Enzyme Database: 2.5.1.131

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