KEGG   ENZYME: 2.5.1.27
Entry
EC 2.5.1.27                 Enzyme                                 

Name
adenylate dimethylallyltransferase;
cytokinin synthase (ambiguous);
isopentenyltransferase (ambiguous);
2-isopentenyl-diphosphate:AMP Delta2-isopentenyltransferase;
adenylate isopentenyltransferase (ambiguous);
IPT
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
Sysname
dimethylallyl-diphosphate:AMP dimethylallyltransferase
Reaction(IUBMB)
dimethylallyl diphosphate + AMP = diphosphate + N6-(dimethylallyl)adenosine 5'-phosphate [RN:R04038]
Reaction(KEGG)
R04038
Substrate
dimethylallyl diphosphate [CPD:C00235];
AMP [CPD:C00020]
Product
diphosphate [CPD:C00013];
N6-(dimethylallyl)adenosine 5'-phosphate [CPD:C04713]
Comment
Involved in the biosynthesis of cytokinins in plants. Some isoforms from the plant Arabidopsis thaliana are specific for AMP while others also have the activity of EC 2.5.1.112, adenylate dimethylallyltransferase (ADP/ATP-dependent).
History
EC 2.5.1.27 created 1984, modified 2002, modified 2013
Pathway
ec00908  Zeatin biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K10760  adenylate dimethylallyltransferase (cytokinin synthase)
K22871  adenylate dimethylallyltransferase
Genes
PMAX: 117318651
ATH: AT1G25410(IPT6) AT1G68460(IPT1) AT3G19160(IPT8) AT3G23630(IPT7) AT3G63110(IPT3) AT4G24650(IPT4) AT5G19040(IPT5)
ALY: 9303727 9309993 9314564 9319508 9321363 9324728
CRB: 17880049 17881630 17885744 17893373 17893971 17894591 17899213
CSAT: 104699569 104701473 104705566 104706220 104730983 104735965 104741270 104746867 104748316 104749004 104750663 104756961 104759387 104766279 104767634 104770241 104784266 104787884 104788590 104788646 104788907 104792695
EUS: EUTSA_v10006499mg EUTSA_v10009876mg EUTSA_v10015859mg EUTSA_v10019632mg EUTSA_v10022241mg EUTSA_v10022249mg EUTSA_v10026816mg
BRP: 103828720 103830971 103837506 103842115 103845790 103851202 103852484 103859798 103862713 117127968
BNA: 106345617 106355091 106356241 106356242 106357100 106357101 106365430 106370472 106370918 106374178 106374850 106377813 106379815 106385487 106385904 106395095 106395535 106409499 106413713 106420240 106431451 106444096 106444949
BOE: 106298696 106298938 106299932 106304865 106309827 106316542 106319832 106325343 106333499 106340154
RSZ: 108810869 108811090 108811091 108814934 108816322 108831384 108832634 108840120 108840416 108852152 108852963 108858886 108859273 108859686
LJA: Lj0g3v0154359.1(Lj0g3v0154359.1) Lj4g3v2400530.1(Lj4g3v2400530.1) Lj5g3v0962690.1(Lj5g3v0962690.1) Lj5g3v2183860.1(Lj5g3v2183860.1)
DOSA: Os01t0688300-00(Os01g0688300) Os03t0356900-01(Os03g0356900) Os03t0358900-00(Os03g0358900) Os03t0810100-01(Os03g0810100) Os05t0311801-00(Os05g0311801) Os05t0551700-01(Os05g0551700) Os07t0190150-00(Os07g0190150) Os07t0211700-00(Os07g0211700)
AOF: 109848379
DDI: DDB_G0277215(iptA)
DPP: DICPUDRAFT_92712(IPTA)
DDQ: DDI_0145
PSTW: DSJ_22575
XOM: XOO2787(XOO2787)
XOO: XOO2936(MiaA)
XOP: PXO_00142
XOR: XOC_2765
XAL: XALC_2569(tzs)
RSO: RSp1225(tzs)
RSL: RPSI07_mp1252(tzs)
RSN: RSPO_m00787(tzs)
RSM: CMR15_mp20328(tzs)
RSE: F504_4721
RSY: RSUY_44080(tzs)
ATU: Atu6012(ipt) Atu6164(tzs)
ATF: Ach5_51180(ipt)
AVI: Avi_8294(ipt)
RFA: A3L23_04945(fas4)
SBH: SBI_01724
ANA: all0220
AVA: Ava_2711
 » show all
Reference
1  [PMID:499537]
  Authors
Chen CM, Melitz DK.
  Title
Cytokinin biosynthesis in a cell-free system from cytokinin-autotrophic tobacco tissue cultures.
  Journal
FEBS Lett 107:15-20 (1979)
DOI:10.1016/0014-5793(79)80452-4
Reference
2  [PMID:11313355]
  Authors
Takei K, Sakakibara H, Sugiyama T.
  Title
Identification of genes encoding adenylate isopentenyltransferase, a cytokinin biosynthesis enzyme, in Arabidopsis thaliana.
  Journal
J Biol Chem 276:26405-10 (2001)
DOI:10.1074/jbc.M102130200
  Sequence
[ath:AT1G68460]
Reference
3  [PMID:15381407]
  Authors
Sakano Y, Okada Y, Matsunaga A, Suwama T, Kaneko T, Ito K, Noguchi H, Abe I
  Title
Molecular cloning, expression, and characterization of adenylate isopentenyltransferase from hop (Humulus lupulus L.).
  Journal
Phytochemistry 65:2439-46 (2004)
DOI:10.1016/j.phytochem.2004.08.006
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.5.1.27
IUBMB Enzyme Nomenclature: 2.5.1.27
ExPASy - ENZYME nomenclature database: 2.5.1.27
BRENDA, the Enzyme Database: 2.5.1.27
CAS: 72840-95-0

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