KEGG   ENZYME: 2.6.1.108
Entry
EC 2.6.1.108                Enzyme                                 
Name
(5-formylfuran-3-yl)methyl phosphate transaminase;
mfnC (gene name);
[5-(hydroxymethyl)furan-3-yl]methyl phosphate transaminase
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
Sysname
L-alanine:(5-formylfuran-3-yl)methyl phosphate aminotransferase
Reaction(IUBMB)
L-alanine + (5-formylfuran-3-yl)methyl phosphate = pyruvate + [5-(aminomethyl)furan-3-yl]methyl phosphate [RN:R11038]
Reaction(KEGG)
R11038
Substrate
L-alanine [CPD:C00041];
(5-formylfuran-3-yl)methyl phosphate [CPD:C20954]
Product
pyruvate [CPD:C00022];
[5-(aminomethyl)furan-3-yl]methyl phosphate [CPD:C21068]
Comment
A pyridoxal 5'-phosphate protein. The enzyme, characterized from the archaebacterium Methanocaldococcus jannaschii, participates in the biosynthesis of the cofactor methanofuran. Requires pyridoxal 5'-phosphate.
History
EC 2.6.1.108 created 2015
Pathway
ec00680  Methane metabolism
ec01100  Metabolic pathways
Orthology
K19793  (5-formylfuran-3-yl)methyl phosphate transaminase
Genes
THIPN838_12830
PACEA6070_12195
PEFA7E78_07625
DVEDESUT3_31870
DPGDESPIGER_0708
DFLDFE_0184
DSDGD606_15175
DMADMR_45090
DCBC3Y92_19395
DGGDGI_1983
DMSE8L03_06035
DEJAWY79_08275
PPRFDPRO_2977(mfnC)
PSELGM415_08330
DSXGD604_15970
DMLDmul_38010(aspC3)
DATHRM2_10800(aspC2)
DOVDSCO28_45510
DWDDSCW_41700
DALKDSCA_41500
DLIdnl_50660
DMMdnm_029950
DAXFDQ92_12000
DBRDeba_0092
BBEBBR47_31990
BFMBP422_11130
PPQPPSQR21_011610
CCHLFPL14_20410
CALKHUE98_09150
LPILLIP_0260
SSYIEKG83_24635
BTHOBtheta7330_04576(patA_2)
BXYBXY_47810
BOABovatus_03826(patA_3)
DRCG0Q07_10800
MCOSGM418_26720
MJAMJ_0684
MFEMefer_0615
MVUMetvu_0344
MFSMFS40622_1497
MJHJH146_1215
MESGMLAUSG7_1004(mfnC)
MESAMLASG1_0773(mfnC)
MIGMetig_0137
MBAMbar_A1546
MBYMSBRM_2902
MBWMSBRW_3183
MBARMSBR2_2861
MBAKMSBR3_1827
MACMA_0636(aspC)
MMAMM_1802
MMAZMmTuc01_1875
MMJMSMAS_2883
MMACMSMAC_1551
MVCMSVAZ_2704
MEKMSKOL_2708
MLSMSLAZ_0359
METMMSMTP_2810
MEFMSWH1_2805
MEQMSWHS_2230
MSJMSSAC_0572
MSZMSSIH_0522
MSWMSSIT_0552
MTHRMSTHT_2208
MTHEMSTHC_1072
MHORMSHOH_3582
MFZAOB57_004795
MMETMCMEM_1376
MELOJ7W08_05520
MMHMmah_1336
MHAZBHR79_06985
MPYMpsy_0899
MZIHWN40_04100
MHZMetho_0766
MCJMCON_2279(aspC)
MHIMhar_2101
MPDMCP_1841
HSLOE_2619F(aspC3)
HDLHALDL1_11575
HAGSJT689_05895
HABOJRZ79_04360
HLULT972_04750
HANRLJ422_04590
HALHHTSR_0784(aspC2)
HHSRHSR6_0811(aspC2)
HSUHLASF_1472(aspC5)
HSFHLASA_1459(aspC5)
SALRFQU85_08450
HLTI7X12_18610
HAQDU484_02795
HAJDU500_03220
HAERDU502_01015
HRAEI982_12430
NAJB1756_18480
NAGAArcMg_1101
NANAArc1_2522
 » show all
Reference
1  [PMID:24977328]
  Authors
Miller D, Wang Y, Xu H, Harich K, White RH
  Title
Biosynthesis of the 5-(Aminomethyl)-3-furanmethanol moiety of methanofuran.
  Journal
Biochemistry 53:4635-47 (2014)
DOI:10.1021/bi500615p
  Sequence
[mja:MJ_0684]
Other DBs
ExplorEnz - The Enzyme Database: 2.6.1.108
IUBMB Enzyme Nomenclature: 2.6.1.108
ExPASy - ENZYME nomenclature database: 2.6.1.108
BRENDA, the Enzyme Database: 2.6.1.108

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