KEGG   ENZYME: 2.6.1.109
Entry
EC 2.6.1.109                Enzyme                                 

Name
8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase;
kdnA (gene name)
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
Sysname
8-amino-3,8-dideoxy-alpha-D-manno-octulosonate:2-oxoglutarate aminotransferase
Reaction(IUBMB)
8-amino-3,8-dideoxy-alpha-D-manno-octulosonate + 2-oxoglutarate = 8-dehydro-3-deoxy-alpha-D-manno-octulosonate + L-glutamate
Reaction(KEGG)
(other) R11395
Substrate
8-amino-3,8-dideoxy-alpha-D-manno-octulosonate;
2-oxoglutarate [CPD:C00026]
Product
8-dehydro-3-deoxy-alpha-D-manno-octulosonate;
L-glutamate [CPD:C00025]
Comment
The enzyme, characterized from the bacterium Shewanella oneidensis, forms 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate, an aminated form of Kdo found in lipopolysaccharides of members of the Shewanella genus. cf. EC 1.1.3.48, 3-deoxy-alpha-D-manno-octulosonate 8-oxidase.
History
EC 2.6.1.109 created 2015
Orthology
K19715  8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase
Genes
SON: SO_2476
SDN: Sden_2132
SFR: Sfri_1761
SAZ: Sama_1641
SBL: Sbal_2373
SBM: Shew185_2361
SBN: Sbal195_2476
SBP: Sbal223_1986
SBT: Sbal678_2478
SBS: Sbal117_2505
SLO: Shew_1858
SSE: Ssed_2422
SHL: Shal_2314
SWD: Swoo_2184
SWP: swp_2702
SVO: SVI_1929
SPSW: Sps_00649
SBK: SHEWBE_2916(kdnA)
SKH: STH12_01316(arnB)
SCAA: TUM17387_18780(kdnA)
TCX: Tcr_2139
HMAR: HVMH_2251(kdnA)
TZO: THMIRHAT_01680(kdnA)
DPS: DP1941
DSF: UWK_02931
DOL: Dole_3203
DAL: Dalk_0883
DOV: DSCO28_27070(kdnA)
DWD: DSCW_63360(kdnA)
DALK: DSCA_59390(kdnA)
DLI: dnl_32050
SAT: SYN_02056
DBR: Deba_0659
TAI: Taci_1278
TLI: Tlie_0563
CPI: Cpin_0802
FLN: FLA_5379
SLI: Slin_2804
FLM: MY04_1600
MARM: YQ22_15670
CBAL: M667_14775
CBAT: M666_14725
MLT: VC82_2956
WIN: WPG_2736
AALG: AREALGSMS7_04131(kdnA)
SPON: HME9304_03325(wbpE)
KOS: KORDIASMS9_03070(kdnA)
KAN: IMCC3317_45580(kdnA)
MARF: CJ739_3663
MESQ: C7H62_2665
 » show all
Reference
1  [PMID:23413030]
  Authors
Gattis SG, Chung HS, Trent MS, Raetz CR
  Title
The origin of 8-amino-3,8-dideoxy-D-manno-octulosonic acid (Kdo8N) in the lipopolysaccharide of Shewanella oneidensis.
  Journal
J Biol Chem 288:9216-25 (2013)
DOI:10.1074/jbc.M113.453324
  Sequence
[son:SO_2476]
Other DBs
ExplorEnz - The Enzyme Database: 2.6.1.109
IUBMB Enzyme Nomenclature: 2.6.1.109
ExPASy - ENZYME nomenclature database: 2.6.1.109
BRENDA, the Enzyme Database: 2.6.1.109

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