KEGG   ENZYME: 2.6.1.109
Entry
EC 2.6.1.109                Enzyme                                 
Name
8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase;
kdnA (gene name)
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
Sysname
8-amino-3,8-dideoxy-alpha-D-manno-octulosonate:2-oxoglutarate aminotransferase
Reaction(IUBMB)
8-amino-3,8-dideoxy-alpha-D-manno-octulosonate + 2-oxoglutarate = 8-dehydro-3-deoxy-alpha-D-manno-octulosonate + L-glutamate
Reaction(KEGG)
(other) R11395
Substrate
8-amino-3,8-dideoxy-alpha-D-manno-octulosonate;
2-oxoglutarate [CPD:C00026]
Product
8-dehydro-3-deoxy-alpha-D-manno-octulosonate;
L-glutamate [CPD:C00025]
Comment
The enzyme, characterized from the bacterium Shewanella oneidensis, forms 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate, an aminated form of Kdo found in lipopolysaccharides of members of the Shewanella genus. cf. EC 1.1.3.48, 3-deoxy-alpha-D-manno-octulosonate 8-oxidase.
History
EC 2.6.1.109 created 2015
Orthology
K19715  8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase
Genes
SONSO_2476
SDNSden_2132
SFRSfri_1761
SAZSama_1641
SBLSbal_2373
SBMShew185_2361
SBNSbal195_2476
SBPSbal223_1986
SBTSbal678_2478
SBSSbal117_2505
SBBSbal175_2010
SLOShew_1858
SSESsed_2422
SHEShewmr4_1853
SHMShewmr7_2125
SHNShewana3_1908
SHLShal_2314
SWDSwoo_2184
SWPswp_2702
SVOSVI_1929
SHFCEQ32_05205
SJASJ2017_2241
SPSWSps_00649
SBJCF168_11170
SMAVCFF01_10070
SHEWCKQ84_20690
SALGBS332_18890
SLJEGC82_12950
SMAIEXU30_01055
SPOLFH971_08665
SBKSHEWBE_2916(kdnA)
SKHSTH12_01316(arnB)
SLITJQC75_08195
SDKKHX94_17815
SCAATUM17387_18780(kdnA)
SPSHFM037_12455
SEURFM038_013205
SYKKDN34_08385
SCYPJYB88_09490
SSEMJYB85_09705
SGLAFJ709_08350
SXMMKD32_09550
SVMKDH10_000740
TCXTcr_2139
HTREPV75_11755
HMARHVMH_2251(kdnA)
TCYThicy_0075
TAOTHIAE_00480
THIOAYJ59_01145
THIGFE785_10505
TIBTHMIRHAM_22010(kdnA)
TZOTHMIRHAT_01680(kdnA)
SHDSUTH_03378
DPSDP1941
DSFUWK_02931
DAKDaAHT2_0945
DPRDespr_1064
DEOCAY53_03855
DOGHP555_13540
DBKDGMP_15160(kdnA)
DOLDole_3203
DMLDmul_14440
DALDalk_0883
DTOTOL2_C12570
DOVDSCO28_27070(kdnA)
DWDDSCW_63360(kdnA)
DALKDSCA_59390(kdnA)
DLIdnl_32050
DMMdnm_065170
SATSYN_02056
DTIDesti_2928
DBRDeba_0659
SRIMCP984_18240
SSUBCP968_05800
SCOECP976_29215
TAITaci_1278
TLITlie_0563
AMOAnamo_0328
CPORBED41_03565
CPICpin_0802
CHITFW415_04000
CHIHGWR21_19585
COYHF329_25085
CFILMYF79_04000
CHFKTO58_23645
NKONiako_6241
FGGFSB75_15275
ARBA9P82_08645
ARKD6B99_01875
FLNFLA_5379
PSEGD3H65_23505
PGINFRZ67_09625
PGOFSB84_06350
FLSGLV81_01600
FLPLK994_04075
FLVKJS94_15445
SEDTTEGAF0_16090(kdnA)
SCNSolca_3571
SLISlin_2804
SRDSD10_14800
SMONAWR27_24360
SPIRCWM47_00650
SPIKEXU85_18840
SPIBG8759_31780
SRHOHH216_12960
CHRWKA713_00130
RSIRunsl_3570
RUNDR864_07925
RUPDTQ70_05240
FLMMY04_1600
FLLEI427_09795
FYAKMW28_08205
FKAKM029_00745
CHKD4L85_02655
RBIRB2501_14269
CATCA2559_06270
FBCFB2170_12561
MARMYQ22_15670
MARTBTR34_15530
MARBCJ263_00045
MAREEJ994_06035
CAOCelal_3619
CLYCelly_3038
CLHIX49_15320
CBALM667_14775
CBATM666_14725
LANLacal_2197
LVNBWR22_09230
LACICW733_03215
ZGAZOBELLIA_4625
MRSMurru_3316
MLTVC82_2956
MUTGVT53_08315
MAQILDL77_19005
SPONHME9304_03325(wbpE)
ASLAeqsu_3069
AEVEI546_01345
AICJK629_14135
WINWPG_2736
WIJBWZ20_14770
SZEAW14_13120
AHZAPS56_02460
SYISB49_03280
FORFORMB_25820
FOHFORMA_18200
FOPFNB79_00400
SEONBWZ22_15280
AALGAREALGSMS7_04131(kdnA)
OLLCW732_11005
OAQDZC78_00510
FEKC1H87_01875
TAJC1A40_17795
AUEC5O00_11085
KOSKORDIASMS9_03070(kdnA)
KANIMCC3317_45580(kdnA)
MARFCJ739_3663
AQBD1818_24600
AQAD1815_07685
AQDD1816_06985
EMARD1013_12980
MUREQY75_05530
PSYNE9099_18385
OCIFEZ18_00090
MGELG5B37_04745
MESQC7H62_2665
GAAHX109_13255
CAGGHYG79_16075
ALTIALE3EI_2524
MARXINR76_09975
SINHLS482_15815
ASAGFGM00_08320
FLGLV716_15575
FLBLV704_16960
SABUMBM09_08390
BIAGMA17_05680
FBMMQE35_00340
FBUUJ101_00786
APIBG8C43_02775
 » show all
Reference
1  [PMID:23413030]
  Authors
Gattis SG, Chung HS, Trent MS, Raetz CR
  Title
The origin of 8-amino-3,8-dideoxy-D-manno-octulosonic acid (Kdo8N) in the lipopolysaccharide of Shewanella oneidensis.
  Journal
J Biol Chem 288:9216-25 (2013)
DOI:10.1074/jbc.M113.453324
  Sequence
[son:SO_2476]
Other DBs
ExplorEnz - The Enzyme Database: 2.6.1.109
IUBMB Enzyme Nomenclature: 2.6.1.109
ExPASy - ENZYME nomenclature database: 2.6.1.109
BRENDA, the Enzyme Database: 2.6.1.109

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