KEGG   ENZYME: 2.7.1.213
Entry
EC 2.7.1.213                Enzyme                                 
Name
cytidine kinase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
Sysname
ATP:cytidine 5'-phosphotransferase
Reaction(IUBMB)
ATP + cytidine = ADP + CMP [RN:R00513]
Reaction(KEGG)
R00513;
(other) R00964 R01666
Substrate
ATP [CPD:C00002];
cytidine [CPD:C00475]
Product
ADP [CPD:C00008];
CMP [CPD:C00055]
Comment
The enzyme, characterized from the archaeon Thermococcus kodakarensis, participates in a pathway for nucleoside degradation. The enzyme can also act on deoxycytidine and uridine, but unlike EC 2.7.1.48, uridine kinase, it is most active with cytidine.
History
EC 2.7.1.213 created 2016
Pathway
ec00240  Pyrimidine metabolism
ec01100  Metabolic pathways
Orthology
K21057  cytidine kinase
K22026  nucleoside kinase
Genes
NOHG5V57_09000
CBTCLH_3246
CLBClo1100_3013
CCLClocl_2480
CCECcel_1080
CCELCCDG5_0763
ACOLK5I23_12490
CCOMI6K69_07805
LBWC3V36_01730
VGUHYG85_10135
TNRThena_0742
TACITDSAC_0711
HALSD7D81_02150
OLSOlsu_1249
TPAVHRQ91_00140
TAMTheam_1686
DTEDester_0039
MJAMJ_0406
MFEMefer_1313
MVUMetvu_0829
MFSMFS40622_1675
MIFMetin_0950
MJHJH146_1321
MESGMLAUSG7_0701
MESAMLASG1_0143
MIGMetig_0129
MMPMMP0418
MMQMmarC5_1220
MMXMmarC6_0492
MMZMmarC7_1416
MMDGYY_02160
MMAKMMKA1_04370(pfkB)
MMAOMMOS7_04330(pfkB)
MMADMMJJ_06190(adoK)
MAEMaeo_1201
MVNMevan_1406
MVOMvol_1641
MOKMetok_0835
METFCFE53_03915
MTHMTH_1544
MMGMTBMA_c01300
MWOMWSIV6_0084(rbsK)
MTEEMTTB_15630
METCMTCT_1409
METEtca_01493(adoK)
METZMETMT2_0044
METKFVF72_03900
MTHMFZP57_00360
METJFZP68_05355
MSTMsp_0252
METBAW729_05925
MRUmru_0246
MSIMsm_1389
MEBAbm4_0153
MMILsm9_2189
MEYETL18_00860
MOLYLM1_0015
MAROMarbSA_13460
METVK4897_04365
MELMetbo_2524
MEWMSWAN_0107
METHMBMB1_0093
MFCBRM9_0158
MFIDSM1535_1480
MCUBMCBB_0117
MSUBBK009_10315
METNBK008_05935
METTCIT01_06160
METOCIT02_06550
MEMEHYG87_07025
MFVMfer_0189
PYCTQ32_02245
TKOTK1843
TONTON_1686
TGATGAM_0187
TSITSIB_1949
TBATERMP_01910
THEGQS_06905
THATAM4_1366
THMCL1_1013
TLTOCC_10494
THSTES1_1867
TNUBD01_1774
TEUTEU_02660
TGYX802_04890
TPEPA0127_05975
TPIEA7C91_03685
TGGA3K92_08745
TCEA3L02_07180
TBSA3L01_09300
THHCDI07_09240
TSLA3L11_02800
TTDA3L14_00350
TPRFA3L09_01070
TRLA3L10_08755
TPAFA3L08_02230
THYA3L12_00155
TICFH039_00935
TCQTIRI35C_2199
THEMFPV09_09135
THEIK1720_02480
PPACPAP_03105
MBAMbar_A2903
MBYMSBRM_1434
MBWMSBRW_1835
MBARMSBR2_0971
MBAKMSBR3_0268
MACMA_1373
MMAMM_2358
MMAZMmTuc01_2409
MMJMSMAS_2341
MMACMSMAC_2104
MVCMSVAZ_1777
MEKMSKOL_1753
MLSMSLAZ_0958
METMMSMTP_2169
MEFMSWH1_2302
MEQMSWHS_2773
MSJMSSAC_1381
MSZMSSIH_1577
MSWMSSIT_1669
MTHRMSTHT_0846
MTHEMSTHC_2425
MHORMSHOH_2963
MFZAOB57_012265
MBUMbur_0967
MMETMCMEM_1470
MELOJ7W08_06110
MMHMmah_0649
MHAZBHR79_00120
MEVMetev_1413
MZHMzhil_0761
MPYMpsy_3162
MZIHWN40_07890
MHZMetho_1694
MHUMhun_0077
MRTJKHC33_04560
MLAMlab_0932
MEMMemar_0859
MBGBN140_0912(pfkB)
MEMAMMAB1_1189
MCHKMchiMG62_09930
MPIMpet_2014
MENDL6E24_10560
MBNMboo_1658
MFOMetfor_2415
MPLMpal_1085
MEAMMU439_05570
TACTa0880
TVOTVG1031550(TVG1031550)
PTOPTO1237
FACFACI_IFERC01G1340
FAIFAD_0353
CDIVCPM_1288
TARTALC_00049
MAXMMALV_00600
MERMMINT_02620
MEARMpt1_c11870
MEUZKRP56_00565
MARCAR505_1785
ABIAboo_0480
ACFAciM339_0562
FLTSv326_1301
LOKILokiarch_18030
 » show all
Reference
1  [PMID:25822915]
  Authors
Aono R, Sato T, Imanaka T, Atomi H
  Title
A pentose bisphosphate pathway for nucleoside degradation in Archaea.
  Journal
Nat Chem Biol 11:355-60 (2015)
DOI:10.1038/nchembio.1786
  Sequence
[tko:TK1843]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.213
IUBMB Enzyme Nomenclature: 2.7.1.213
ExPASy - ENZYME nomenclature database: 2.7.1.213
BRENDA, the Enzyme Database: 2.7.1.213

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