KEGG   ENZYME: 2.7.1.216
Entry
EC 2.7.1.216                Enzyme                                 
Name
farnesol kinase;
FOLK (gene name)
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
Sysname
CTP:(2E,6E)-farnesol phosphotransferase
Reaction(IUBMB)
CTP + (2E,6E)-farnesol = CDP + (2E,6E)-farnesyl phosphate [RN:R09849]
Reaction(KEGG)
R09849
Substrate
CTP [CPD:C00063];
(2E,6E)-farnesol [CPD:C01126]
Product
CDP [CPD:C00112];
(2E,6E)-farnesyl phosphate [CPD:C20121]
Comment
The enzyme, found in plants and animals, can also use other nucleotide triphosphates as phosphate donor, albeit less efficiently. The plant enzyme can also use geraniol and geranylgeraniol as substrates with lower activity, but not farnesyl phosphate (cf. EC 2.7.4.32, farnesyl phosphate kinase) [2].
History
EC 2.7.1.216 created 2017
Pathway
ec00900  Terpenoid backbone biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K15892  farnesol kinase
Genes
ATHAT5G58560(FOLK)
ALY9302348
CRB17875624 17886534
CSAT104698976 104711386 104726429 104735756 104761955 104780712
EUSEUTSA_v10014180mg
BRP103845287 103856674 103856907
BNA106376298 106385189 106385190 106420546 106435924 106435934
BOE106313208 106334947 106334948
RSZ108823783 108848087 108848088
THJ104799389 104799865
CPAP110823862
CIT102607196
CICCICLE_v10028969mg
PVY116130238
MINC123209613
TCC18590992
GRA105783806 105789011
GHI107927038 107936061 107957660 107963843
GAB108480963 108484512
DZI111286046 111301486
EGR104418390 104418391 104418392 104456195
GMX100793696
GSJ114397687
PVUPHAVU_006G071000g
VRA106752668
VAR108341074
VUN114187077
CCAJ109814795
APRC113850147
MTRMTR_3g465120 MTR_4g015990 MTR_4g016040
CAM101508675 101508996
LJALj0g3v0022429.1(Lj0g3v0022429.1) Lj0g3v0338869.1(Lj0g3v0338869.1)
ADU107473329
AIP107648557
AHF112719976 112792546
LANG109352111
FVE101312326
RCN112166567
PPER18773060
PMUM103321386
PAVI110758741
PDUL117632803
MDM103419955
PXB103958984
ZJU107411489
MNT21394929
CSV101220953
CMO103497053
BHJ120082414
MCHA111018992
CMAX111469454 111493313
CMOS111452098 111464846
CPEP111782599 111787425
RCU8272401
JCU105639148
HBR110634309
MESC110605789
POP18109105 7487814
PEU105110415 105126052
PALZ118027566 118032874 118055597
JRE108996986
QSU112003510
QLO115989892
TWL120003144
VVI100243279 100265588
VRI117915594 117916906
SLY101252619
SPEN107029162
SOT102606110
CANN107851334
NTA107798184 107802957 107825879
NSY104237922
NTO104088379 104098382
NAU109214544
INI109164267
ITR116015191
SIND105177430 105177431
OEU111367046 111400761 111402577
EGT105964397 105964400
SSPL121756461 121760315 121762773 121763215 121764574 121764706 121793031
HAN110884628 110936154 110939702
ECAD122592675 122592836 122608516
LSV111881754 111881777 111900633
CCAV112518182
DCR108215602 108223537
CSIN114258091
BVG104903117
SOE110803557 110803567
CQI110681594 110711948
NNU104602694
MING122089913
TSS122638290
PSOM113284213 113355432
NCOL116262082 116262083
OSA4327435 4349551 4351259
DOSAOs01t0832000-01(Os01g0832000) Os11t0105800-01(Os11g0105800) Os12t0105500-01(Os12g0105500)
OBR102715340 102717944
BDI100826738 100838535
ATS109769583 109780312 109780318
TDC119269473 119272646 119277476 119301004
TAES123044293 123057026 123062489 123062936 123065878 123071295 123076365 123079639 123106884 123115995 123124621
TUA125521241 125525062 125545199 125546997 125555917
SBI8055486 8079965 8085428
ZMA100191275
SITA101761907 101778737 101781291
SVS117857107 117864528 117866590
PVIR120643375 120674265 120685552 120694042 120696498 120708549
PHAI112878635 112886295 112893785 112902701
PDA103718108 103722776
EGU105036025
MUS103999851
DCT110098089
PEQ110018674 110026549
AOF109829993
ATR18437155
SMOSELMODRAFT_230719 SELMODRAFT_95672
PPP112279064 112294085
APROF751_5656
SREPTSG_03426
EHXEMIHUDRAFT_369009 EMIHUDRAFT_436338
 » show all
Reference
1  [PMID:9606952]
  Authors
Bentinger M, Grunler J, Peterson E, Swiezewska E, Dallner G
  Title
Phosphorylation of farnesol in rat liver microsomes: properties of farnesol kinase and farnesyl phosphate kinase.
  Journal
Arch Biochem Biophys 353:191-8 (1998)
DOI:10.1006/abbi.1998.0611
Reference
2  [PMID:21395888]
  Authors
Fitzpatrick AH, Bhandari J, Crowell DN
  Title
Farnesol kinase is involved in farnesol metabolism, ABA signaling and flower development in Arabidopsis.
  Journal
Plant J 66:1078-88 (2011)
DOI:10.1111/j.1365-313X.2011.04572.x
  Sequence
[ath:AT5G58560]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.216
IUBMB Enzyme Nomenclature: 2.7.1.216
ExPASy - ENZYME nomenclature database: 2.7.1.216
BRENDA, the Enzyme Database: 2.7.1.216

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