KEGG   ENZYME: 2.7.7.71
Entry
EC 2.7.7.71                 Enzyme                                 
Name
D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase;
hddC (gene name);
gmhD (gene name)
Class
Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
Sysname
GTP:D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase
Reaction(IUBMB)
D-glycero-alpha-D-manno-heptose 1-phosphate + GTP = GDP-D-glycero-alpha-D-manno-heptose + diphosphate [RN:R09772]
Reaction(KEGG)
R09772
Substrate
D-glycero-alpha-D-manno-heptose 1-phosphate [CPD:C19880];
GTP [CPD:C00044]
Product
GDP-D-glycero-alpha-D-manno-heptose [CPD:C19881];
diphosphate [CPD:C00013]
Comment
The enzyme is involved in biosynthesis of GDP-D-glycero-alpha-D-manno-heptose, which is required for assembly of S-layer glycoprotein in some Gram-positive bacteria.
History
EC 2.7.7.71 created 2010
Pathway
ec00540  Lipopolysaccharide biosynthesis
ec01100  Metabolic pathways
Orthology
K15669  D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase
Genes
YPBYPTS_1057
YPQDJ40_1346
YPUBZ21_256
YPRBZ20_1033
YPCBZ23_532
PLUplu4824(wblY)
PLUMA4R40_23995
LSOLGOY17_03460
LHXLYSHEL_08780(hddC)
LCASLYSCAS_08780(hddC)
THESFHQ07_06195
TCNH9L16_07625
TBVH9L17_06855
VAFD1115_23000
VSRVspart_00205(rfbF_2)
VZIG5S32_14895
PGBH744_2c2396
PGHFH974_09830
PPBPPUBIRD1_1474
PALLUYA_23035
PBZGN234_10455
PKHJLK41_16275
PMUYKSS95_17175
PORYEJA05_20070
PWZJ7655_08605
PAGRE2H98_17305
SBBSbal175_1479
AMAGI533_13330
CEBB0D95_15710
ASIPAQUSIP_18120(hddC_2)
METLU737_03410
MMOBF6R98_01285
MEINmethR_P2383
MESLKKZ03_15205
HTREPV75_08905
TVIThivi_4047
HCHHCH_06180
HAHEENC22_26650
TOLTOL_2195
TORR615_06680
REUReut_A0722
CUPBKK80_17030
CUUBKK79_15325
BMABMA2294(hddC)
BMVBMASAVP1_A0534(hddC)
BMLBMA10229_A1066(wcbM)
BMNBMA10247_2172(wcbM)
BMALDM55_1490
BMAEDM78_2664
BMAQDM76_1468
BMAIDM57_1069
BMAFDM51_1935
BMAZBM44_1069
BMABBM45_2460
BPSBPSL2794(wcbM)
BPMBURPS1710b_3290(wcbM)
BPLBURPS1106A_3276(wcbM)
BPDBURPS668_3241(wcbM)
BPRGBP346_A3419
BPSEBDL_2651
BPSMBBQ_515
BPSUBBN_643
BPSDBBX_1049
BPZBP1026B_I0516(wcbM)
BPQBPC006_I3324
BPKBBK_2136
BPSHDR55_1724
BPSABBU_2768
BPSOX996_1364
BUTX994_3362
BTDBTI_922
BTHADR62_527
BCEWDM40_4221
BLATWK25_23470
BSTLBBJ41_08330
BPLAbpln_1g18360
BUZAYM40_03130 AYM40_03410
BCAIK788_0007829
PHSC2L64_13955
PMEGFNZ07_18190
PACSFAZ98_02535
RSBRS694_17780
HSEHsero_4416
HSZACP92_22055
HFRG5S34_23460
MASSCR152_19315
AONDEH84_17470
NETNeut_0159
MEHM301_2250
MBATBN1208_0915
MEUACJ67_08020
ARESIWH25_01540
HWIA0Z60_06595
CJECj1423c(hddC)
CJBBN148_1423c(hddC)
CJJCJJ81176_1422
CJNICDCCJ07001_1353
CJSCJS3_1516
CJEJN564_02350
CJEUN565_02430
CJENN755_02485
CJEIN135_01513
CJERH730_08135
CJYQZ67_01562(hddC_2)
CJQUC78_1364(hddC_2)
CJWPJ18_07290
CJRCJE1608
CJDJJD26997_1755
CJZM635_02840
CJXBN867_14000
CLRUPTC16701_0318
CLMUPTC16712_0316
CLNUPTC3659_0328
CCFYSQ_01745
CISCINS_0294
CAMRCAQ16704_0317
CSMCSUB8521_0329
CHVCHELV3228_0219
CCUNCCUN_1150
CLXCLAN_0154
CHWA2J15_004895
CAMZCVIC12175_0186
COJCORN_0315
CUXCUP3940_1431
CARMCARM_0283
CNVCNZW441b_0370
ANTArnit_2924
ALKALEK_0997
AMYTAMYT_0705
GLOGlov_0792
DMADMR_p1_00350
DOVDSCO28_03320
HMRHipma_1691
RENEF513_03800
BRND1F64_11925
CSECseg_1878
CMBCSW64_13085
BNDKWG56_04320
MAGamb0798
MAGXXM1_1801
MAGNWV31_16780
FERFNB15_03140
APBSAR116_0975
PPSCEHS13_28190
PRZGZH47_12300
ASOCCB4_00634(hddC)
CACCA_C3056
CAESMB_G3092
CAYCEA_G3062
CFERD4Z93_01725
PBIFKXZ80_16775
CSHClosa_3799
DECDCF50_p1136
AOCAocu_04610(hddC)
EYYEGYY_07220(GCD1)
SYZMYO_122470
SYYSYNGTS_2223(slr0007)
SYTSYNGTI_2222(slr0007)
SYSSYNPCCN_2221(slr0007)
SYQSYNPCCP_2221(slr0007)
SYJD082_33180
SYOC7I86_11615
PMHP9215_14341
GENGM3709_95
GEEGM3708_2173
MARMAE_55660
MPKVL20_391
MIQB5D77_10620
MVZmyaer102_27900
CANCyan10605_0114
CYUUCYN_11560
CYTcce_0965
CWACwatDRAFT_2259
CYPPCC8801_1636
CYHCyan8802_1663
CEOETSB_0017
CERRGRSB_1051
SNGSNE_A16750(mpg1)
ULIETAA1_11120(hddC)
KSTKSMBR1_2292
BPITBPIT_11880 BPIT_20160
FVAFV113G1_09570(hddC)
ACOAmico_1360
TLITlie_1237
AMOAnamo_1480
BTHBT_0476
BTHOBtheta7330_02886(hddC_2)
BFGBF638R_1446
ALDGFH31_01605
AITAI2BBH_01750
CPICpin_3113
CHIHGWR21_07435
COYHF329_02880
NKONiako_2549
NSONIASO_09040
NIAA8C56_12860
FLASY85_01480
ARKD6B99_15400
FLNFLA_2279
PSEGD3H65_10795
PGINFRZ67_05020
PGOFSB84_23210
FLSGLV81_14345
FEIK9M53_08230
FLPLK994_12850
PAAPaes_1744
NDENIDE3423
LFILFML04_1776
TCMHL41_06280
MPIMpet_1391
 » show all
Reference
1  [PMID:11279237]
  Authors
Kneidinger B, Graninger M, Puchberger M, Kosma P, Messner P
  Title
Biosynthesis of nucleotide-activated D-glycero-D-manno-heptose.
  Journal
J Biol Chem 276:20935-44 (2001)
DOI:10.1074/jbc.M100378200
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.7.7.71
IUBMB Enzyme Nomenclature: 2.7.7.71
ExPASy - ENZYME nomenclature database: 2.7.7.71
BRENDA, the Enzyme Database: 2.7.7.71

DBGET integrated database retrieval system