KEGG   ENZYME: 2.7.8.28
Entry
EC 2.7.8.28                 Enzyme                                 
Name
2-phospho-L-lactate transferase;
cofD (gene name);
fbiA (gene name);
LPPG:Fo 2-phospho-L-lactate transferase;
LPPG:7,8-didemethyl-8-hydroxy-5-deazariboflavin 2-phospho-L-lactate transferase;
lactyl-2-diphospho-(5')guanosine:Fo 2-phospho-L-lactate transferase
Class
Transferases;
Transferring phosphorus-containing groups;
Transferases for other substituted phosphate groups
Sysname
(2S)-lactyl-2-diphospho-5'-guanosine:7,8-didemethyl-8-hydroxy-5-deazariboflavin 2-phospho-L-lactate transferase
Reaction(IUBMB)
(1) (2S)-lactyl-2-diphospho-5'-guanosine + 7,8-didemethyl-8-hydroxy-5-deazariboflavin = GMP + factor 420-0 [RN:R09398];
(2) enolpyruvoyl-2-diphospho-5'-guanosine + 7,8-didemethyl-8-hydroxy-5-deazariboflavin = GMP + dehydro factor 420-0 [RN:R12648];
(3) 3-[(R)-glyceryl]-diphospho-5'-guanosine + 7,8-didemethyl-8-hydroxy-5-deazariboflavin = GMP + 3PG-factor 420-0 [RN:R12649]
Reaction(KEGG)
Substrate
(2S)-lactyl-2-diphospho-5'-guanosine [CPD:C19155];
7,8-didemethyl-8-hydroxy-5-deazariboflavin [CPD:C19154];
enolpyruvoyl-2-diphospho-5'-guanosine [CPD:C22297];
3-[(R)-glyceryl]-diphospho-5'-guanosine [CPD:C22298]
Product
GMP [CPD:C00144];
factor 420-0 [CPD:C19153];
dehydro factor 420-0 [CPD:C22277];
3PG-factor 420-0 [CPD:C22299]
Comment
This enzyme is involved in the biosynthesis of factor 420, a redox-active cofactor, in methanogenic archaea and certain bacteria. The specific reaction catalysed in vivo is determined by the availability of substrate, which in turn is determined by the enzyme present in the organism - EC 2.7.7.68, 2-phospho-L-lactate guanylyltransferase, EC 2.7.7.105, phosphoenolpyruvate guanylyltransferase, or EC 2.7.7.106, 3-phospho-D-glycerate guanylyltransferase.
History
EC 2.7.8.28 created 2010, modified 2020
Pathway
ec00680  Methane metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K11212  LPPG:FO 2-phospho-L-lactate transferase
Genes
VAQFIV01_04145(cofD)
PPHABVH74_17765
CPSCPS_4047(cofD)
ALTambt_18400
AALEP13_00570
ASPAOR13_3370
ASQAVL57_01935
AAWAVL56_00745
ALEAV939_00750
ALZAV940_00750
SNANI6N98_10725
ZALAZF00_12045
OSGBST96_15200
MAGAMag101_11135
HJABST95_09650
HALCEY643_13160
KIMG3T16_02860
MPCMar181_0280
MPRIMP3633_0354(cofD)
MFOIJSY38_07520
MRHIKDW99_18325
MARSA8C75_03575
MRZKDW95_12770
SDFACG33_05470
BPYBphyt_4253
PSPWBJG93_33620(cofD)
BRHRBRH_02552
PUDG9Q38_02360
DOEDENOEST_3711(cofD)
EBAp2A344
AZDCDA09_09445
THUAC731_008655
TAKTharo_0192
PAUUE8A73_035580(cofD)
HOHHoch_0060
MESPC1M53_21075
SMEGC770_GR4pC0059
SMERDU99_18230
ARUIG6M88_23520
KAIK32_16290
BICLMTR13_24640
BRKCWS35_20190
BQBJ4P68_0009790(cofD)
RPBRPB_4407
OCAOCAR_5005(cofD)
OCGOCA5_c29530(cofD)
SNOSnov_4232
STARG3545_06900
LNEFZC33_07440
APRAG3A50_17780
MOGMMB17_16630(cofD)
HMCHYPMC_3549
METGHT051_05400 HT051_12620
NTDEGO55_02480
CAENK5X80_05810(cofD)
RBMTEF_10860
PSFPSE_2791
CAULKCG34_11235
PZUPHZ_c2538
LMDMETH_04445
LAQUR2C4_00570
LCAEK3721_20515(cofD)
PDEPden_1116
RMBK529_001415
THASC6Y53_09635
NPNJI59_17705
NREBES08_02710 BES08_26375
NOVTQ38_007745
SPHOC3E99_13155
SPHUSPPYR_1433(cofD)
SWISwit_0414
SPHDHY78_26025
RDICMV14_13680
SPHMG432_18315
SPKCKC8_00655
SBINSBA_ch2_1010
SCHSphch_2203
SYBTZ53_04410
SBDATN00_13425
SPMIK663_16405
SPHBEP837_01487(cofD)
SPHTK426_20935
SHYDCJD35_15475
SYAA6768_05855
SCLOSCLO_1006400
SUFLFIL70_15530
SBARH5V43_13880
SPPHKFK14_07110
BLASBSY18_2468(cofD)
SPHJBSL82_04910 BSL82_08905
CMANA9D14_14815
KHAIFJ82_10835
MTURv3261(fbiA)
MTVRVBD_3261
MTCMT3359
MRAMRA_3302(fbiA)
MTFTBFG_13290
MTBTBMG_03309
MTKTBSG_03332
MTZTBXG_003289
MTIMRGA423_20435
MTECCDC5079_3009
MTURCFBS_3450(fbiA)
MTLCCDC5180_2972
MTOMTCTRI2_3328(fbiA)
MTDUDA_3261(fbiA)
MTNERDMAN_3575(fbiA)
MTJJ112_17520
MTUBMT7199_3303
MTUEJ114_17480
MTXM943_16845
MTULTBHG_03197
MTUTHKBT1_3437(fbiA)
MTUUHKBT2_3444(fbiA)
MTQHKBS1_3447(fbiA)
MBOBQ2027_MB3289(fbiA)
MBBBCG_3290(fbiA)
MBTJTY_3286(fbiA)
MBMBCGMEX_3288(cofD)
MBKK60_033900
MBXBCGT_3128
MAFMAF_32720(fbiA)
MMICRN08_3596
MCEMCAN_32801(fbiA)
MCQBN44_70046(cofD)
MCVBN43_60271(cofD)
MCXBN42_41312(cofD)
MCZBN45_60291(cofD)
MLEML0759
MLBMLBr00759
MPAMAP_3374
MAOMAP4_0408
MAVIRC58_01950
MAVURE97_01960
MAVMAV_4224(cofD)
MITOCO_40830
MIAOCU_40740
MIDMIP_06148
MYOOEM_41090
MCHIAN480_21440
MIROCQ_42100
MMALCKJ54_19475
MLPMLM_3383
MMANMMAN_28870(cofD)
MSAMycsm_01371
MULMUL_2606(fbiA)
MMIMMAR_1281(fbiA)
MMAEMMARE11_12470(fbiA)
MLIMULP_01442(fbiA)
MPSEMPSD_14590(cofD)
MSHOMSHO_60290(cofD)
MMCMmcs_1324
MKMMkms_1341
MJLMjls_1360
MMMW7S_20385
MKNMKAN_21200
MYVG155_09335
MYEAB431_07860
MGOAFA91_29760
MHADB586_17490
MDXBTO20_26030
MSHGMSG_01181(cofD)
MFJMFLOJ_22070(cofD)
MSTOMSTO_25780(cofD)
MSIMMSIM_13080(cofD)
MSAKMSAS_48340(cofD)
MKUI2456_06475
MGROFZ046_13190
MXEMYXE_37090(cofD)
MNVMNVI_28180(cofD)
MPAGC0J29_07135
MNMMNVM_30590(cofD)
MGORH0P51_06360 H0P51_22655
MCOOMCOO_44640(cofD)
MBAIMB901379_01172
MSEOMSEO_51130(cofD)
MHEKJMUB5695_03654(cofD)
MGAUMGALJ_57760(cofD)
MLJMLAC_04500(cofD)
MBRDMBRA_03610(cofD)
MSHJMSHI_24900(cofD)
MKRMKOR_20210(cofD)
MDFK0O62_07965(cofD)
MMAMK3U93_05775(cofD)
MHOLK3U96_19385(cofD)
MHERK3U94_17035(cofD)
MSENK3U95_20440(cofD)
MPAEK0O64_07425(cofD)
MSPGF6B93_05485
MOTLTS72_18965(cofD)
MLMMLPF_1195(cofD)
MVMMJO54_17055(cofD)
MRFMJO55_07470(cofD)
MPAAMKK62_18620(cofD)
MCROMI149_08405(cofD)
MSMMSMEG_1830(cofD)
MSGMSMEI_1787(cofD)
MSBLJ00_09125
MSNLI99_09125
MSHLI98_09125
MVAMvan_1733
MGIMflv_4730
MSPMspyr1_40640
MCBMycch_1342
MNED174_08425
MYNMyAD_08280
MFTXA26_18670
MPHLMPHLCCUG_01627(cofD)
MVQMYVA_1477(cofD)
MLLB1R94_21305
MRHMycrhN_0422
MTHN4412656_01187(cofD)
MHASMHAS_00504(cofD)
MDUMDUV_28070(cofD)
MCHTMCHIJ_50200(cofD)
MDRMDOR_09070(cofD)
MAUUNCTC10437_01440
MMAGMMAD_14830(cofD)
MMORMMOR_51210(cofD)
MFXMFAL_19170(cofD)
MAICMAIC_13040(cofD)
MIJMINS_15980(cofD)
MALVMALV_19530(cofD)
MTYMTOK_35140(cofD)
MPSCMPSYJ_49680(cofD)
MARZMARA_24290(cofD)
MGADMGAD_25250(cofD)
MHEVMHEL_36240(cofD)
MSARMSAR_04240(cofD)
MANYMANY_52690(cofD)
MAUBMAUB_17090(cofD)
MPOFMPOR_20180(cofD)
MPHUMPHO_54240(cofD)
MMUCC1S78_020460
MMATMMAGJ_47590(cofD)
MBOKMBOE_56000(cofD)
MFGK6L26_23195(cofD)
MSEIMSEDJ_27370(cofD)
MFLVNCTC10271_03863
MCEEMCEL_20340(cofD)
MBRML2Z93_003006(cofD)
MABMAB_3607
MMVMYCMA_05825
MABBMASS_3614
MABLMMASJCM_3604
MCHEBB28_18450
MIZBAB75_20515
MSTEMSTE_03739(cofD)
MSAOMYCSP_16595
MSALDSM43276_03405(cofD)
MJDJDM601_3010(fbiA)
MTER4434518_02997(fbiA)
MMINMMIN_07410(cofD)
MHIBMHIB_24540(cofD)
ASDAS9A_3810(fbiA)
MPAKMIU77_13975(cofD)
NFANFA_46210
NFRERS450000_05307
NBRO3I_035160
NNONONO_c63250(cofD)
NSLBOX37_24640
NSRNS506_02072(cofD)
NTPCRH09_32620
NOZDMB37_13820
NODFOH10_03600
NAHF5544_37075
NADNCTC11293_05925
NWLNWFMUON74_13460(cofD)
NIEKV110_34195(cofD)
NTCKHQ06_12815
NHUH0264_12270
NYALTV02_20670(cofD)
NGPLTT66_19770(cofD)
RHARHA1_ro06312
RERRER_21530(fbiA)
REYO5Y_10285
REBXU06_10510
RQIC1M55_10950
ROPROP_63740(fbiA)
ROAPd630_LPD02976
RPYY013_07655
RBYCEJ39_18575
RHBNY08_1683
RAVAAT18_17230
RFAA3L23_00047(cofD)
RHSA3Q41_03366(cofD)
RHWBFN03_04465
RRZCS378_06785
RHUA3Q40_02034(cofD)
RHQIM25_21970
RHODAOT96_21130
RRT4535765_03351(fbiA)
RCRNCTC10994_03906
RTMG4H71_17765
RKOJWS14_25815 JWS14_34325
RGOKYT97_07795(cofD)
ROZCBI38_19200
RPSKJWS13_09595
REQREQ_33510
GBRGbro_3302
GPOGPOL_c30980(cofD)
GORKTR9_3342
GOQACH46_06015
GTABCM27_16970
GOCCXX93_08505
GITC6V83_14655
GRUGCWB2_17190(cofD)
GOMD7316_05387(cofD)
GAVC5O27_11010
GODGKZ92_16070
GAMGII34_16025
GPDGII33_15465
GJIH1R19_16010
GOILK459_17880(cofD)
GHNMVF96_16435(cofD)
GAMIIHQ52_19975(cofD)
GMGNWF22_01500(cofD)
TPRTpau_1183
TSMASU32_06665
TPULTPB0596_34390(cofD)
SRTSrot_2670
DTMBJL86_1020
DITC3V38_10630
DIZCT688_04540
DPCA6048_04615
DLUA6035_04850
DKNNHB83_04370
SCOSCO3036(SCE34.17)
SALBXNR_1923
SMASAVERM_5040(cofD)
SGRSGR_4501
SGBWQO_13015
SCBSCAB_55061(cofD)
SSXSACTE_2502
SVLStrvi_8422
SHYSHJG_4503
SHOSHJGH_4266
SRCM271_29480
SMALSMALA_3141
SSOII1A49_19500
SFASfla_3871
SBHSBI_04465
SVESVEN_2778
SDVBN159_5256(cofD)
SALSSLNWT_2576
STRPF750_2861
SFISFUL_2632
SCIB446_15765
SALUDC74_3465
SALLSAZ_18450
SLVSLIV_22515(cofD)
SGUSGLAU_13800(cofD)
SVTSVTN_14810
STREGZL_05425
SCWTU94_13260
SLDT261_5068
SLCSL103_04170
SXISXIM_18230
STRMM444_14300
STRCAA958_11400
SAMBSAM23877_3078(cofD)
SPRISPRI_4521
SCZABE83_22880
SCXAS200_27270
SRWTUE45_04629(cofD)
STRFASR50_20140
SLEsle_42450(sle_42450)
SRNA4G23_02039(cofD)
SPAVSpa2297_13145
STRTA8713_12280
SCLFBB341_17715
SGSAVL59_42920
STSIA4E84_15950
SKYD0C37_11380
SALWCP975_13850
SGMGCM10017557_50180(cofD)
SCADDN051_23470
SPHWNFX46_36010(cofD)
SLSSLINC_3442
SNRSNOUR_25330(cofD)
SPLULK06_011880
STRDNI25_23610
SNWBBN63_21605
SAUOBV401_19195
SSIAA7J05_21725
SVUB1H20_12295
SPUNBFF78_25300
SGVB1H19_16740
SLAUSLA_2759
SALFSMD44_03376(cofD)
SALJSMD11_4189(cofD)
SLXSLAV_22860(cofD)
STROSTRMOE7_15720
SFKKY5_3201
SNZDC008_13670
SGEDWG14_05054(cofD)
SRJSRO_4453
SLKSLUN_15500
SDXC4B68_24090
SGDELQ87_23320
SQZFQU76_11440
SCYAEJ357_18275
SASTCD934_20165
SNQCP978_14100
STIRDDW44_10215
SKACP970_26370
SGZC0216_27100
SVNCP980_20520
SNKCP967_21065
SHAWCEB94_16540
SRKFGW37_12635
SFICEIZ62_20210
SGALCP966_14460
SSPODDQ41_08705
SVRCP971_20720
SPADDVK44_11195
SFYGFH48_24390
SAQUEJC51_20730
SGFHEP81_04780
SCAVCVT27_11710
SSEOD0Z67_11255
SBYH7H31_22370
SRIMCP984_24930
SSUBCP968_20300
SPHVF9278_18575
SCINCP977_13485
SFUGCNQ36_13860
SPACB1H29_22325
STSUB7R87_11090
SCHACP983_26050
SGXH4W23_16030
SCOECP976_17675
SBATG4Z16_21470
SSPBCP982_17985
SNFJYK04_03613(cofD)
SPLACP981_15390
SBROGQF42_18830
STUIGCM10017668_27340(cofD)
SATAC5746_16550
SCHFIPT68_14685
SHUNDWB77_04647(cofD)
SHARHUT13_11495
SCYGS1361_16335(cofD)
SFEUIM697_05855
SLIAHA039_21545
SDWK7C20_14505(cofD)
SVDCP969_16335
SCALI6J39_12565
SAUHSU9_012970
SFBCP974_11280
SMOBJ7W19_12335
SPRACP972_14535
SPEUCGZ69_13685
SROIIAG44_24885
SXNIAG42_21215
SGJIAG43_12130
SHKJ2N69_14065(cofD)
SANUK7396_22170(cofD)
SDDD9753_21325
SACTDMT42_15900
SMAOCAG99_17350
SGOBtest1122_08555(cofD)
SINEKI385_18460(cofD)
SLFJEQ17_28340
SDECL3078_18485(cofD)
SAOVG3H79_22490
SDURM4V62_25485(cofD)
SYANNRK68_13430(cofD)
SCTSCAT_2043(cofD)
SCYSCATT_20250
KSKKSE_29430(fbiA)
KABB7C62_12010
KAUB6264_15385
KITCFP65_2739
STRIC7M71_010635
YIALO772_21670(cofD)
STRHGXP74_06015
ABRYNYE86_05090(cofD)
LXLKDY119_01330(cofD)
PSICJ4E96_05905
MTSMTES_1873
MCWA8L33_02355
MIHBJP65_10325
MLVCVS47_03060(cofD)
MWAE4K62_17135(cofD)
MPRTET475_03960(cofD)
MSEDE3O41_07825(cofD)
MSFIT882_16035(cofD)
MCAWF6J84_13730(cofD)
MLZF6J85_16155(cofD)
MBINLXM64_14510(cofD)
RTXTI83_05460
RTCAPU90_01015
RTNA6122_1538
RRYC1O28_07045
RIAC7V51_05515
RFSC1I64_04310
RTEGSU10_08575
AGYATC03_18350
AGMDCE93_13635
AGFET445_04955
AMAUDSM26151_27910(fbiA)
ASOIMTP13_06345(cofD)
CARTPA27867_3302
CPHYB5808_11950
HUMDVJ78_09000
HUWFPZ11_07335
GRYD7I44_06895
MANTBHD05_14670
HEAHL652_10800
HEHL3i23_06180(cofD)
GLNF1C58_11305
CHREIE160_09575(cofD)
AGXAGREI_1001(fbiA)
SUBTKPL76_08075
SUBALQ955_10135(cofD)
DAYFV141_09350
DERMH7F30_07875
LMOIVV02_10695
YIMJ5M86_04320
ALXLVQ62_16225(cofD)
XCEXcel_3009
XYLET495_10985
XYAET471_03440
IVAIsova_2671
IDOI598_2998(cofD)
CETB8281_07125
CCEUCBR64_04235
SKESked_24050
CFICelf_1450
CGACelgi_2151
CEJGC089_11365
CELHGXP71_04070
CIRALFM56_11085(cofD)
CELCK5O09_06690(cofD)
CFENKG102_06220
OEKFFI11_000580
ICAIntca_2520
ARSADJ73_09015
JTEASJ30_11180 ASJ30_13400
JLIEXU32_03175
JMEEEW87_003975
JAYH7A72_11415
TEHGKE56_00815
PEIH9L10_02750
SERJSGUI_1033
SERWFY030_04075
ORNDV701_06625
ORZFNH13_13675
BRIFDF13_08045
AUSIPK37_14460(cofD)
GYUFE374_01130
MPHMLP_39300(cofD)
MIKFOE78_07435
MICGGJV80_00180
NCANoca_1410
NDKI601_0152(cofD)
NOYEXE57_06555
NOIFCL41_12290
NOOFE634_07295
NDPE2C04_12860
NBEBack2_26820(cofD)
NANOG5V58_15765
NMESH9L09_04150
NAROCFH99_18250
NPIG7071_09230
NAQUENKNEFLB_03314(cofD)
NROK8W59_12195(cofD)
NOQLN652_18835(cofD)
NCQK6T13_04835(cofD)
NPCKUV85_01620(cofD)
NPSKRR39_14595(cofD)
PSIMKR76_19800
AEZC3E78_12880
AEBC6I20_11375
AEFGEV26_02940 GEV26_12935
MUZH4N58_15560
KFLKfla_1587
KQIF1D05_27420
TFUTfu_2517
THAONI17_015395
TALXFOF52_12865
NDANdas_3767
NALB005_0945(cofD)
NGVCDO52_24245
NEXNE857_28260(cofD)
STRREKD16_04585(cofD)
SAIUJ4H86_12275
TCUTcur_4072
ACTWF7P10_11795
AGRAAGRA3207_002958
SROSros_1380
NOABKM31_38770
NOWGBF35_06600
NCXNocox_05955(cofD)
NGNLCN96_06645(cofD)
TBITbis_0749
FRAFrancci3_0742
FREFranean1_5868
FRIFraEuI1c_6071
FALFRAAL1260
FSYFsymDg_1077
ACEAcel_0455
NMLNamu_4175
NAKEH165_10585
GOBGobs_4304
BSDBLASA_4121(cofD)
BLAPMVA48_20180(cofD)
MMARMODMU_4702(cofD)
KRAKrad_3851
SENSACE_6466
SACGFDZ84_07205
SVISvir_06240
SACCEYD13_03500(cofD)
AMDAMED_1023(cofD)
AMNRAM_05205
AMMAMES_1019(cofD)
AMZB737_1020(cofD)
AOIAORI_1010(cofD)
AJAAJAP_34530(cofD)
AMQAMETH_0932(cofD)
AMYCCU254_03585
AMYBBKN51_39155
AABA4R43_35500
AMYYYIM_42555(cofD)
AORISD37_36140
AACDLWP59_04475(cofD)
APRTMUY14_31680(cofD)
AROONQK81_17830(cofD)
PDXPsed_1331 Psed_5208
PSEAWY02_11520
PSEEFRP1_02690
PSEHXF36_02095
PSEQAD006_10305
PECQAD017_18135
PHHAFB00_16165
PAUTPdca_56450(cofD)
PBROHOP40_13550
APRECNX65_31165
AMIAmir_6333
SESPBN6_76240
SSYIEKG83_42415
KALKALB_7913
KPHYAOZ06_48150
LEDBBK82_19185
AHMTL08_23380
ACTIUA75_27200
ACADUA74_26610
AHGAHOG_24530(cofD)
ACTAC1701_14680
ALOCRK59728
PMADBAY61_03995
SACEGIY23_18805
ACTUActkin_05519
STPStrop_0944
SAQSare_0886
MAUMicau_0952
MILML5_1200
MICBMicB006_0998
MTUACSH63_19730
MICHFJK98_05050
MTEMGCE86_30270
MCABHXZ27_05700
MSAGGCM10017556_35210(cofD)
VMAVAB18032_09465
MCRAID554_08065
ASEACPL_1048(fbiA)
AMSAMIS_8540
ACTNL083_1151(fbiA)
AFSAFR_05650
ACTSACWT_0930
AIHAiant_52210(cofD)
ACTRAsp14428_35950(cofD)
PLKCIK06_05190
PLABC6361_20385
PLATC6W10_23375
PFLAPflav_062080(cofD)
PSUUPsuf_024020(cofD)
VERHUT12_05625
ATLAthai_49510(cofD)
ASERAsera_25010(cofD)
PRYPrubr_13810(cofD)
CATICS0771_04610(cofD)
DFUDfulv_43310(cofD)
DROSDrose_33160
DAURDaura_46965
NHYJQS43_20530
CCAZCOUCH_33980(cofD)
CAICaci_7611
AEYCDG81_04210
EKEEK0264_15480
JTLM6D93_14715(cofD)
ABAIIMCC26256_111646
RXYRxyl_0958
RRDRradSPS_0868
RMARGBA65_08890
BSOLFSW04_11720
CWOCwoe_4149
PARNNBH00_07370(cofD)
SBAEDSM104329_01287(fbiA_1) DSM104329_01863(fbiA_2)
AFOAfer_0741
AYMYM304_28610(fbiA)
ATQGH723_12310
AQZKSP35_00880(cofD)
IAMHC251_16060
ERZER308_14060
EUZDVS28_a4425
RRSRoseRS_1138
RCARcas_3979
CAUCaur_0204
CHLChy400_0218
CAGCagg_0665
TROtrd_A0801(cofD)
STISthe_2613
ATMANT_14430
ABATCFX1CAM_1027(cofD)
PSUBPelsub_P1766
LEKhrd7_26920
CAPCLDAP_12760(cofD)
PBFCFX0092_A2821(cofD)
KBSEPA93_18910
TBHTbon_06685
THUGKNN16_07965
TTRTter_1864
PMETG4Y79_17600
MJAMJ_1256
MFEMefer_0031
MVUMetvu_0809
MFSMFS40622_0677
MIFMetin_0575
MJHJH146_0469
MESGMLAUSG7_1279(cofD)
MESAMLASG1_0497(cofD)
MIGMetig_1491
MMPMMP0404(cofD)
MMQMmarC5_1234
MMXMmarC6_0506
MMZMmarC7_1402
MMDGYY_02090
MMAKMMKA1_04230(cofD)
MMAOMMOS7_04190(cofD)
MMADMMJJ_06330(cofD)
MAEMaeo_0819
MVNMevan_1392
MVOMvol_1651
MOKMetok_0351
METFCFE53_04155
MTHMTH_1018
MMGMTBMA_c14000(cofD)
MWOMWSIV6_1404(cofD)
MTEEMTTB_04060
METCMTCT_0926
METEtca_00979(cofD)
METZMETMT2_1044
METKFVF72_06520
MTHMFZP57_06710
METJFZP68_03950
MSTMsp_1403(cofD)
METBAW729_08505
MRUmru_1844(cofD)
MSIMsm_0974
MEBAbm4_1487(cofD)
MMILsm9_1937(cofD)
MEYETL18_09140
MOLYLM1_1301
MAROMarbSA_16660
METVK4897_06605(cofD)
MELMetbo_2436
MEWMSWAN_0206
METHMBMB1_0200(cofD)
MFCBRM9_2100(cofD)
MFIDSM1535_1581(cofD)
MCUBMCBB_0215(cofD)
MSUBBK009_10795
METNBK008_06435
METTCIT01_02830
METOCIT02_06015
MEMEHYG87_04415
MFVMfer_0319
MKAMK1489
AFUAF_0917
AFGAFULGI_00010030
APOArcpr_1471
AVEArcve_0317
ASTAsulf_01226
FPLFerp_0960
GACGACE_1169
GAHGAH_01892
MBAMbar_A1631
MBYMSBRM_0533
MBWMSBRW_3100
MBARMSBR2_1845
MBAKMSBR3_1916
MACMA_0714
MMAMM_1874
MMAZMmTuc01_1948
MMJMSMAS_2813
MMACMSMAC_1625
MVCMSVAZ_2561
MEKMSKOL_2569
MLSMSLAZ_0397
METMMSMTP_2712
MEFMSWH1_0464
MEQMSWHS_0475
MSJMSSAC_0660
MSZMSSIH_0603
MSWMSSIT_0634
MTHRMSTHT_1404
MTHEMSTHC_1885
MHORMSHOH_3512
MFZAOB57_005975
MBUMbur_1411
MMETMCMEM_1896
MELOJ7W08_08440
MMHMmah_1721
MHAZBHR79_05100
MEVMetev_0504
MZHMzhil_1840
MPYMpsy_2105
MZIHWN40_11685
MHZMetho_2233
MTPMthe_1438
MCJMCON_1062(cofD)
MHIMhar_0950
MHUMhun_2444
MRTJKHC33_16865
MLAMlab_0152
MEMMemar_2144 Memar_2145
MBGBN140_1350(cofD1) BN140_1351(cofD2)
MEMAMMAB1_1720(cofD) MMAB1_1721
MCHKMchiMG62_24560 MchiMG62_24570
MSUMOH143_05010(cofD)
MPIMpet_1887 Mpet_1889
MENDL6E24_01005(cofD)
MBNMboo_0117
MFOMetfor_0245
MPLMpal_2578
MPDMCP_1915(cofD)
MEZMtc_1637(cofD)
RCIRRC453(cofD)
HALVNG_1429C
HSLOE_3057F(cofD)
HDLHALDL1_12565
HHBHhub_2871(cofD)
HAGSJT689_07140
HABOJRZ79_05575(cofD)
HNOLT974_11120(cofD)
HLULT972_03675(cofD)
HANRLJ422_05825(cofD)
HJEHacjB3_07015
HALHHTSR_0535
HHSRHSR6_0519
HSUHLASF_1691
HSFHLASA_1678
SALRFQU85_12630
HALREFA46_000610
HAADMW046_04935(cofD)
HALXM0R89_00415(cofD)
HAXZM0R88_00425(cofD)
SALIL593_00185
SAIMK0C01_03595(cofD)
HARAAArcS_1459(cofD)
HMArrnAC0051
HHIHAH_0810
HHNHISP_04195
HABSG26_11910
HTABVU17_03985
HALJG9465_13585
HSINKDQ40_09460
NPHNP_2028A(cofD)
NMONmlp_3454(cofD)
NHOHWV23_03700
NSALHWV07_19045
HUTHuta_0762
HTIHTIA_0655
HALAHrd1104_04245
HMUHmuk_2581
HALZE5139_00175
HALLLC1Hm_1922(cofD)
HAZPGBQ70_00175
HALIBV210_16050
HSNDV733_11815
HDSHSR122_1780(cofD)
HRRHZS55_20720
HPELHZS54_24170
HLTI7X12_15205
HARCHARCEL1_06895
HDOMUK72_11245(cofD)
SSAIN0B31_08175(cofD)
HWAHQ_3012A(cofD)
HWCHqrw_3528(cofD)
HVOHVO_2479(cofD)
HMEHFX_2485
HGIABY42_12390
HALEG3A49_15620
HLSKU306_00535(cofD)
HBOHbor_11120
HAQDU484_13470
HAJDU500_13495
HAERDU502_10730
HRAEI982_01655
HLMDV707_05055
HALMFCF25_04540
HLAHlac_2334
HALPDOS48_11785
HALBEKH57_13340
HEZZEO776_12975
HALQHrr1229_009040
HSSJ7656_03315
HSAIHPS36_08660
HAZZKI388_11530
SRUBC2R22_11755
HAEhalTADL_0704
HALNB4589_005915
HALGHUG10_03145
HALUHUG12_13710
HMPK6T50_01380(cofD)
HREK6T36_01180(cofD)
HRMK6T25_00130(cofD)
HACBHbl1158_08300(cofD)
HDFAArcSl_0948(cofD)
HAHHalar_1768
HTUHtur_1894
HDABB347_05240
HSALJMJ58_19920
HLOJ0X27_01635
HAKZJ0X25_16190(cofD)
NMGNmag_0613(cofD)
HXAHalxa_2708
NATNJ7G_0764
NPENatpe_2234
NVRFEJ81_10100
NPLFGF80_01720
NAYHYG81_00920(cofD)
HALYHYG82_02660
HJTDVR14_19220 DVR14_23350
NGENatgr_0322
HRUHalru_1715
NOUNatoc_3578
HLRHALLA_12590
HLCCHINAEXTREME12800
NAJB1756_01600
NAGAArcMg_2242
NANAArc1_1444
NBGDV706_14510
NASGCU68_14710
SAWLNGM29_11995(cofD)
MELUMTLP_06820
MEAMMU439_06170(cofD)
NMRNmar_0626
NIRNSED_03225
NKRNKOR_03205
NIDNPIRD3C_1641
NINNADRNF5_1524(cofD)
NIWNisw_01780
NCLC5F47_05945
NOXC5F49_05785
NUEC5F50_04635
NIPNsoK4_05235
NCTNMSP_1058(cofD)
NICDSQ20_03325
CSYCENSYa_1217
NGANgar_c13870(cofD)
NVNNVIE_001510(cofD)
NEVNTE_01463
TAANMY3_01423(cofD)
NFNNFRAN_2318(cofD)
NCVNCAV_1164
CSUCSUB_C1237
NBVT478_0979(cofD)
TAHSU86_003065
NIUDSQ19_03545
NDVNDEV_0695(cofD)
CCAINAS2_0477
LOKILokiarch_23950(cofD_1) Lokiarch_46980(cofD_2)
 » show all
Reference
1  [PMID:11888293]
  Authors
Graupner M, Xu H, White RH
  Title
Characterization of the 2-phospho-L-lactate transferase enzyme involved in coenzyme F(420) biosynthesis in Methanococcus jannaschii.
  Journal
Biochemistry 41:3754-61 (2002)
DOI:10.1021/bi011937v
  Sequence
[mja:MJ_1256]
Reference
2  [PMID:18252724]
  Authors
Forouhar F, Abashidze M, Xu H, Grochowski LL, Seetharaman J, Hussain M, Kuzin A, Chen Y, Zhou W, Xiao R, Acton TB, Montelione GT, Galinier A, White RH, Tong L
  Title
Molecular insights into the biosynthesis of the F420 coenzyme.
  Journal
J Biol Chem 283:11832-40 (2008)
DOI:10.1074/jbc.M710352200
  Sequence
[mma:MM_1874]
Reference
3  [PMID:31469543]
  Authors
Braga D, Last D, Hasan M, Guo H, Leichnitz D, Uzum Z, Richter I, Schalk F, Beemelmanns C, Hertweck C, Lackner G
  Title
Metabolic Pathway Rerouting in Paraburkholderia rhizoxinica Evolved Long-Overlooked Derivatives of Coenzyme F420.
  Journal
ACS Chem Biol 14:2088-2094 (2019)
DOI:10.1021/acschembio.9b00605
Other DBs
ExplorEnz - The Enzyme Database: 2.7.8.28
IUBMB Enzyme Nomenclature: 2.7.8.28
ExPASy - ENZYME nomenclature database: 2.7.8.28
BRENDA, the Enzyme Database: 2.7.8.28

DBGET integrated database retrieval system