KEGG   ENZYME: 2.7.8.38
Entry
EC 2.7.8.38                 Enzyme                                 

Name
archaetidylserine synthase
Class
Transferases;
Transferring phosphorus-containing groups;
Transferases for other substituted phosphate groups
Sysname
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol:L-serine 2,3-bis-(O-geranylgeranyl)-sn-glycerol phosphotransferase
Reaction(IUBMB)
(1) CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol + L-serine = CMP + 2,3-bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine [RN:R10255];
(2) CDP-2,3-bis-(O-phytanyl)-sn-glycerol + L-serine = CMP + 2,3-bis-(O-phytanyl)-sn-glycero-1-phospho-L-serine [RN:R10441]
Reaction(KEGG)
R10255 R10441
Substrate
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol;
L-serine [CPD:C00065];
CDP-2,3-bis-(O-phytanyl)-sn-glycerol [CPD:C20627]
Product
CMP [CPD:C00055];
2,3-bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine;
2,3-bis-(O-phytanyl)-sn-glycero-1-phospho-L-serine [CPD:C20628]
Comment
Requires Mn2+. Isolated from the archaeon Methanothermobacter thermautotrophicus.
History
EC 2.7.8.38 created 2013, modified 2013
Pathway
ec00564  Glycerophospholipid metabolism
Orthology
K19665  archaetidylserine synthase
Genes
MJA: MJ_1212
MFE: Mefer_0273
MVU: Metvu_1372
MFS: MFS40622_0843
MIF: Metin_0469
MJH: JH146_0624
MIG: Metig_0758
MMP: MMP1171(pssA)
MMQ: MmarC5_0416
MMX: MmarC6_1500
MMD: GYY_06700
MMAK: MMKA1_13490(pssA)
MMAO: MMOS7_12790(pssA)
MMAD: MMJJ_16740
MAE: Maeo_1058
MVO: Mvol_0960
METF: CFE53_05690(pssA)
MTH: MTH_1027
MMG: MTBMA_c14090(pssA)
METC: MTCT_0935
METE: tca_00988
METK: FVF72_06475(pssA)
MTHM: FZP57_06755(pssA)
MST: Msp_1394
MRU: mru_1834(pssA)
MSI: Msm_0982
MEB: Abm4_1497
MMIL: sm9_1037(pssA)
MEYE: TL18_09180
MOL: YLM1_1292
METH: MBMB1_0210
MFC: BRM9_2090(pssA)
MCUB: MCBB_0224
METT: CIT01_02880(pssA)
METO: CIT02_05970(pssA)
MKA: MK0161(pssA)
AFU: AF_2044
FPL: Ferp_1409
GAC: GACE_0950
GAH: GAH_01927
MBAR: MSBR2_2259
MBAK: MSBR3_2310
MAC: MA_0116(pss)
MMA: MM_1403
MMAC: MSMAC_3281
MTHR: MSTHT_1900
MTHE: MSTHC_1383
MHOR: MSHOH_4008
MMET: MCMEM_0374
MMH: Mmah_0393
MPY: Mpsy_2327
MTP: Mthe_1331
MCJ: MCON_0461(pssA)
MHI: Mhar_2192
HAL: VNG_0784G(pssA)
HSL: OE_2155R(pgsA3)
HHB: Hhub_1848(pgsA1)
HALH: HTSR_1242(pssA)
HHSR: HSR6_1314(pssA)
HSU: HLASF_1159(pssA)
HSF: HLASA_1147(pssA)
HMA: rrnAC0788(pssA)
HHI: HAH_1434(pssA)
NPH: NP_3230A(assA)
NMO: Nmlp_1867(pgsA3)
HUT: Huta_0720
HTI: HTIA_0627
HMU: Hmuk_2392
HALL: LC1Hm_1749(pssA)
HWA: HQ_2356A(assA)
HWC: Hqrw_2603(assA)
HVO: HVO_1143(assA)
HME: HFX_1155(pssA)
HLA: Hlac_0607
HDF: AArcSl_2371(pssA)
HTU: Htur_1508
NMG: Nmag_2425(assA)
NAT: NJ7G_3135
SALI: L593_13620
 » show all
Reference
1  [PMID:12562787]
  Authors
Morii H, Koga Y
  Title
CDP-2,3-Di-O-geranylgeranyl-sn-glycerol:L-serine O-archaetidyltransferase (archaetidylserine synthase) in the methanogenic archaeon Methanothermobacter thermautotrophicus.
  Journal
J Bacteriol 185:1181-9 (2003)
DOI:10.1128/JB.185.4.1181-1189.2003
  Sequence
[mth:MTH_1027]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.8.38
IUBMB Enzyme Nomenclature: 2.7.8.38
ExPASy - ENZYME nomenclature database: 2.7.8.38
BRENDA, the Enzyme Database: 2.7.8.38

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