KEGG   ENZYME: 2.8.3.13
Entry
EC 2.8.3.13                 Enzyme                                 
Name
succinate---hydroxymethylglutarate CoA-transferase;
hydroxymethylglutarate coenzyme A-transferase;
dicarboxyl-CoA:dicarboxylic acid coenzyme A transferase
Class
Transferases;
Transferring sulfur-containing groups;
CoA-transferases
Sysname
succinyl-CoA:3-hydroxy-3-methylglutarate CoA-transferase
Reaction(IUBMB)
succinyl-CoA + 3-hydroxy-3-methylglutarate = succinate + (S)-3-hydroxy-3-methylglutaryl-CoA [RN:R02084]
Reaction(KEGG)
R02084
Substrate
succinyl-CoA [CPD:C00091];
3-hydroxy-3-methylglutarate [CPD:C03761]
Product
succinate [CPD:C00042];
(S)-3-hydroxy-3-methylglutaryl-CoA [CPD:C00356]
Comment
Malonyl-CoA can also act as donor, but more slowly.
History
EC 2.8.3.13 created 1984
Orthology
K18703  succinate---hydroxymethylglutarate CoA-transferase
Genes
HSA79783(SUGCT)
PTR463372(SUGCT)
PPS100986046(SUGCT)
GGO101151689(SUGCT)
PON100439966(SUGCT)
NLE100604796(SUGCT)
MCC702855(SUGCT)
MCF102117690(SUGCT)
MTHB126950120
CSAB103226178(SUGCT)
CATY105597096(SUGCT)
PANU101026871(SUGCT)
TGE112621627(SUGCT)
RRO104663124(SUGCT)
RBB108526580(SUGCT)
TFN117073198(SUGCT) 117086376
PTEH111552261(SUGCT)
CJC100399458(SUGCT)
SBQ101045888(SUGCT)
MMUR105864397(SUGCT)
LCAT123647173(SUGCT)
OGA100946240(SUGCT)
MMU192136(Sugct)
MCAL110308310(Sugct)
MPAH110333816(Sugct)
RNO361253(Sugct)
MCOC116081623(Sugct)
MUN110545457(Sugct)
CGE100770206(Sugct)
MAUA101833330(Sugct)
PLEU114685416(Sugct)
MORG121432683(Sugct)
MFOT126501622
AAMP119816399(Sugct)
NGI103736749(Sugct)
HGL101704628(Sugct)
CPOC100720345(Sugct)
CCAN109699563(Sugct)
DORD105998320(Sugct)
DSP122120845(Sugct)
NCAR124991724
OCU100344733(SUGCT)
OPI101522375(SUGCT)
TUP102500635(SUGCT)
CFA483247(SUGCT)
CLUD112661518(SUGCT)
VVP112925810(SUGCT)
VLG121501632(SUGCT)
AML100466463(SUGCT)
UMR103674695(SUGCT)
UAH113258116(SUGCT)
UAR123789435(SUGCT)
ELK111157075
LLV125080603
MPUF101678901(SUGCT)
ORO101370482(SUGCT)
EJU114213705(SUGCT)
ZCA113911824(SUGCT)
MLX118024574(SUGCT)
NSU110592644(SUGCT)
FCA101090248(SUGCT)
PYU121028929(SUGCT)
PBG122487707(SUGCT)
LRUF124523391
PTG102969712(SUGCT)
PPAD109268012(SUGCT)
AJU106974432(SUGCT)
HHV120235598(SUGCT)
BTA100125578(SUGCT)
BOM102277643(SUGCT)
BIU109557920(SUGCT)
BBUB102403448(SUGCT)
CHX102189185(SUGCT)
OAS101121005(SUGCT)
ODA120877258(SUGCT)
CCAD122438551(SUGCT)
SSC102168155(SUGCT)
CFR102518036(SUGCT)
CBAI105062811(SUGCT)
CDK105088268(SUGCT)
VPC102543595(SUGCT)
BACU103011770(SUGCT)
LVE103073879(SUGCT)
OOR101274229(SUGCT)
DLE111184492(SUGCT)
PCAD102978044(SUGCT)
PSIU116759418(SUGCT)
ECB100063665(SUGCT)
EPZ103548468(SUGCT)
EAI106841054(SUGCT)
MYB102255717(SUGCT)
MYD102755997(SUGCT)
MMYO118665964(SUGCT)
MLF102435391(SUGCT)
MNA107532777(SUGCT)
PKL118711426(SUGCT)
HAI109388809(SUGCT)
DRO112302737(SUGCT)
PDIC114508035(SUGCT)
PHAS123812086(SUGCT)
MMF118619819(SUGCT)
RFQ117012323(SUGCT)
MJV108391317
TOD119241680
SARA101558959(SUGCT)
TMU101358340
DNM101435755(SUGCT)
MDO100017716(SUGCT)
SHR100917495(SUGCT)
PCW110192937(SUGCT)
OAA100076800(SUGCT)
GGA420768(SUGCT)
PCOC116232788(SUGCT)
MGP100541558(SUGCT)
CJO107309842(SUGCT)
NMEL110393207(SUGCT)
APLA101795646(SUGCT)
ACYG106042881(SUGCT)
AFUL116486688(SUGCT)
TGU100220077(SUGCT)
LSR110471392(SUGCT)
SCAN103819414(SUGCT)
PMOA120504990(SUGCT)
OTC121333739(SUGCT)
PRUF121353185(SUGCT)
GFR102042813(SUGCT)
FAB101815381(SUGCT)
PHI102102839(SUGCT)
PMAJ107199809(SUGCT)
CCAE111923670(SUGCT)
CCW104688907(SUGCT)
CBRC103615749(SUGCT)
ETL114068676(SUGCT)
ZAB102069635(SUGCT)
ACHL103797297(SUGCT)
FPG101914214(SUGCT)
FCH102058344(SUGCT)
CLV102092162(SUGCT)
EGZ104124844(SUGCT)
NNI104012418(SUGCT)
ACUN113477581(SUGCT)
TALA116965134(SUGCT)
PADL103914775(SUGCT)
AFOR103895253(SUGCT)
ACHC115339399(SUGCT)
CCRI104164473(SUGCT)
MUI104537493
GSTE104263862(SUGCT)
LDI104345950
MNB103781775
OHA104337152(SUGCT)
NNT104413681(SUGCT)
DPUB104304045(SUGCT)
CVF104290339(SUGCT)
AAM106495271(SUGCT)
AROW112974615(SUGCT)
NPD112943752(SUGCT)
TGT104568245(SUGCT)
DNE112996090(SUGCT)
SCAM104147056(SUGCT)
ASN102380883(SUGCT)
AMJ102565653(SUGCT)
CPOO109310407(SUGCT)
GGN109291651(SUGCT)
PSS102457624(SUGCT)
CMY102938246(SUGCT)
CPIC101932936(SUGCT)
TST117872606(SUGCT)
CABI116832624(SUGCT)
MRV120398457(SUGCT)
ACS100560657(sugct)
PVT110076201(SUGCT)
SUND121935397(SUGCT)
PBI103051719(SUGCT)
PMUR107284934(SUGCT)
CTIG120305244(SUGCT)
TSR106552975(SUGCT)
PGUT117664284(SUGCT)
VKO123035717(SUGCT)
PMUA114607372(SUGCT)
ZVI118091794(SUGCT)
GJA107125736(SUGCT)
STOW125441270(SUGCT)
XLA734617(sugct.L)
XTR100490876(sugct)
NPR108789606(SUGCT)
RTEM120940409(SUGCT)
BBUF121001552(SUGCT)
BGAR122938296(SUGCT)
DRE619244(sugct)
SRX107713787
SANH107683488 107687505
SGH107588103
CAUA113042208(sugct) 113065898 113065921
PPRM120476426(sugct)
MAMB125257585(sugct)
IPU108272202(sugct)
PHYP113545418(sugct)
SMEO124384312(sugct)
TFD113644304(sugct)
AMEX103046221(sugct)
EEE113579379(sugct)
TRU101079570(sugct)
TNGGSTEN00025319G001
LCO104934798(sugct)
NCC104958094
ELY117264419(sugct)
EFO125882107(sugct)
PLEP121960945(sugct)
SLUC116064063(sugct)
PFLV114548902(sugct)
GAT120811329(sugct)
PPUG119198733(sugct)
MSAM119897172(sugct)
ALAT119008526(sugct)
MZE101479221 112435349
ONL100690336(sugct)
OAU116321682(sugct)
OLA101160363(sugct)
OML112151578(sugct)
XMA102217127(sugct)
XCO114136606(sugct)
XHE116711768(sugct)
PRET103460142(sugct)
PFOR103154875(sugct)
PLAI106962312(sugct)
PMEI106912214
GAF122824432(sugct)
CVG107103354(sugct)
CTUL119777283(sugct)
GMU124857978(sugct)
NFU107396590(sugct)
KMR108229515(sugct)
ALIM106527658(sugct)
NWH119426544(sugct)
AOCE111589108
MCEP124995878(sugct)
CSEM103377338(sugct)
POV109643934(sugct)
SSEN122780783 122780784
HHIP117753650(sugct)
HSP118098525(sugct)
LCF108894671
SDU111237409(sugct)
SLAL111644963 111664721
XGL120789894(sugct)
HCQ109530300(sugct)
BPEC110162694(sugct)
MALB109974978(sugct)
BSPL114853963(sugct)
SASA106590081
STRU115195861(sugct)
OTW112228026(sugct)
OMY110490010(sugct)
OGO124039833(sugct)
ONE115130432
SALP111953576(sugct)
SNH120051188(sugct)
CCLU121549544 121569827(sugct)
ELS105019401(sugct)
SFM108942414(sugct)
PKI111837840(sugct)
AANG118224692(sugct)
LOC102695930(sugct)
PSPA121312772(sugct)
ARUT117435489
LCM102363380
CMK103181542(sugct)
RTP109936162
BFO118423924
BBEL109478107
CIN100182301
SCLV120341433
SPU585781 586995
APLC110973554
SKO100367923
DMEDmel_CG10877(CG10877)
DER6553691
DSE6619256
DSIDsimw501_GD20057(Dsim_GD20057)
DYADyak_GE25064 Dyak_GE28146
DAN6501110
DSR110188221
DPO4800239
DPE6595072
DMN108155165
DWI6649635
DGR6569822
DMODmoj_GI10535
DAZ108615476
DNV108653570
DHE111595029 115483326 115483785
DVI6629893
CCAT101457108
BOD106617315
RZE108378193
MDE101898519
SCAC106096348
LCQ111679068
LSQ119608890
HIS119650560
AGAAgaP_AGAP010040 AgaP_AGAP012657
ACOZ120955801
AARA120901503
ASTE118513306
AAG5579340
AALB109622879
CQUCpipJ_CPIJ006279
CPII120428098
CNS116341422
BCOO119066366
AME102653793
ACER108004172
ALAB122716231
BIM100749167
BBIF117204733
BVK117230264
BVAN117163698
BTER100642253
BPYO122571052
CCAL108628205
OBB114878337
MGEN117224449
NMEA116432084
CGIG122401128
SOC105203633
MPHA105835014
AEC105143279
ACEP105623357
PBAR105424931
VEM105569340
HST105184591
DQU106744777
CFO105256083
FEX115243289
LHU105678836
PGC109856317
OBO105278275
PCF106793590
PFUC122516049
VPS122628728
NVI100115846
MDL103577513
CGLO123275389
FAS105267724
DAM107042318
AGIF122851502
LHT122500637
CCIN107266104
TCA660876
DPA109537429
SOY115891529
ATD109600725
CSET123312600
AGB108908928
LDC111502490
NVL108565438
PPYR116170278
OTU111422690
BMOR692874
BMAN114239438
MSEX115445341 119192071
DPLKGM_201877
BANY112049337
NIQ126781002
PMAC106712775
PPOT106110042
PXU106127744
PRAP110991305
ZCE119831325
HAW110380602
HZE124646076
TNL113501138
SLIU111352627
OFU114364331
PXY105381801
CFEL113375088
API100168975
DNX107162995
AGS114124321
RMD113556875
BTAB109030047
DCI103510665
CLEC106670613
HHAL106685649
NLU111052872
PHUPhum_PHUM136910
TPAL117639251
FCD110846887
DPXDAPPUDRAFT_194168
DMK116916092
PVM113814628
PJA122259226
PCHN125037750
HAME121857803
PCLA123772377
PTRU123519491
EAF111698882
PPOI119103441 119103479
ISCIscW_ISCW019410
DSV119443106
RSAN119388229
RMP119185237
VDE111245967
VJA111267468
TUT107361994
PTEP107444806 107455261
SDM118186795
HROHELRODRAFT_110638
LGILOTGIDRAFT_180274
PCAN112565218
BGT106073146
GAE121381171
HRF124116202 124116203
HRJ124278163 124278164
CRG105328315
MYI110464562
PMAX117339526
MMER123532442
OBI106869531
OSN115215758
LAK106181348
NVE5521097
EPA110254819
ATEN116298134
ADF107331705
AMIL114965027
PDAM113670225
SPIS111327396
HMG100199476
TADTRIADDRAFT_23229
QSU111990713 112019720
GSLGasu_01030
YLIYALI0D25542g
SLBAWJ20_1860 AWJ20_4562
NCRNCU07298
NTENEUTE1DRAFT61271(NEUTE1DRAFT_61271)
SMPSMAC_00832
PANPODANS72p089
TTTTHITE_2114834
MTMMYCTH_2298437
CTHRCTHT_0034950
MGRMGG_13032
TMNUCRPA7_6071 UCRPA7_7030
SSCKSPSK_01669 SPSK_06194
FGRFGSG_00600
FPUFPSE_04603 FPSE_08120
FVRFVEG_01062 FVEG_03314 FVEG_14165
FOXFOXG_00449 FOXG_04828 FOXG_17351
NHENECHADRAFT_31128 NECHADRAFT_32911 NECHADRAFT_98391
TRETRIREDRAFT_56625
TRRM419DRAFT_6360
MAWMAC_03060
MAJMAA_04122 MAA_08543
CMTCCM_03858
PLJVFPFJ_01671 VFPFJ_03725
VALVDBG_06377 VDBG_08485
VDAVDAG_03523 VDAG_08150
CFJCFIO01_00198
CHIGCH63R_00209
SAPOSAPIO_CDS3621 SAPIO_CDS7757
ELAUCREL1_9288
PFYPFICI_00057
SSLSS1G_06568
BFUBCIN_11g03150
PSCOLY89DRAFT_657837 LY89DRAFT_691401
GLZGLAREA_02769
ANIAN4230.2
AFMAFUA_1G06250
ACTACLA_028310
NFINFIA_018460
AORAO090001000425
ANGANI_1_676164(An18g05120)
AFVAFLA_012539
ALUCAKAW2_31107S
ACHEACHE_11078A
APUUAPUU_60475A APUU_61245S APUU_80878A
PCSPc13g02780 Pc20g15630
PDPPDIP_69130
TMFPMAA_019920
TRGTRUGW13939_04426 TRUGW13939_07141
CIMCIMG_03524 CIMG_09761
CPWCPC735_007240 CPC735_023060
UREUREG_04685 UREG_07321
PBLPAAG_01935 PAAG_05210
PBNPADG_00608 PADG_05047
ABEARB_05424
TVETRV_03845
AJEHCAG_00060
BGHBDBG_01600 BDBG_06322
PNOSNOG_02523(SNOG_02522) SNOG_04148
PTEPTT_17328
BZECOCCADRAFT_34498 COCCADRAFT_38638
BSCCOCSADRAFT_93056
BORCOCMIDRAFT_98750
AALTCC77DRAFT_1038151 CC77DRAFT_997920
ZTRMYCGRDRAFT_47917 MYCGRDRAFT_84473
PFJMYCFIDRAFT_137416 MYCFIDRAFT_168080 MYCFIDRAFT_46826
FFUCLAFUR5_06764 CLAFUR5_10091
BCOMBAUCODRAFT_21543 BAUCODRAFT_77579
TMLGSTUM_00004537001
CNECNB03190
CNBCNBB2500
CNGCNAG_03829
CGICGB_A3170C
TMSTREMEDRAFT_30357
TASAA1Q1_00178
TVSTRAVEDRAFT_166347
DSQDICSQDRAFT_154003
PCOPHACADRAFT_199064
SHSSTEHIDRAFT_147459
HIRHETIRDRAFT_427231
PSQPUNSTDRAFT_130604
ADLAURDEDRAFT_83962
FMEFOMMEDRAFT_97831
GTRGLOTRDRAFT_42893
LBCLACBIDRAFT_188465
CCICC1G_15019
ABPAGABI1DRAFT113921(AGABI1DRAFT_113921)
ABVAGABI2DRAFT193757(AGABI2DRAFT_193757)
PCUBJR316_0007138
MPRMPER_10942
MRRMoror_15749
MOREE1B28_012571
SCMSCHCO_02532349(SCHCODRAFT_02532349)
CPUTCONPUDRAFT_165469
SLASERLADRAFT_469716
WSEWALSEDRAFT_61531
WICJ056_001902
UMAUMAG_01923
PFPPFL1_00313
PGRPGTG_02159
MLRMELLADRAFT_32982
MBRMONBRDRAFT_27495
SREPTSG_07528
TETTTHERM_00823710
PTMGSPATT00017825001
BXBDR64_8762
AKATKWG_13780
OCAOCAR_6068
OCGOCA5_c19590
OCOOCA4_c19580
FILBN1229_v1_2278
FIYBN1229_v1_2278
SGISGRAN_1465
SPHOC3E99_04085
SPHLLPB140_01035
ABQABAZ39_31950
ABFAMK58_27755
AZTTSH58p_20935
RUEDT065_03525
BBEBBR47_37410
BFMBP422_14070
BAGRBA6348_12390
PNPIJ22_14010
PPSCEHS13_09335
KYRCVV65_14940
DKUDesku_2608
MTYMTOK_21150
ROPROP_28600
PSAIC3B54_111268
NCANoca_0039 Noca_0047
FREFranean1_3138
FFAFFWV33_14425
AQBD1818_05125
FBEFF125_18270
HAQDU484_00895
HAJDU500_01460
HAERDU502_16955
SACDHS1genome_2113
CSUCSUB_C0180
 » show all
Reference
1  [PMID:6946836]
  Authors
Deana R, Rigoni F, Deana AD, Galzigna L.
  Title
Submitochondrial localization and partial purification of the succinylCoA: 3-hydroxy-3-methylglutarate coenzyme A transferase from rat liver.
  Journal
Biochim Biophys Acta 662:119-24 (1981)
DOI:10.1016/0005-2744(81)90231-X
Other DBs
ExplorEnz - The Enzyme Database: 2.8.3.13
IUBMB Enzyme Nomenclature: 2.8.3.13
ExPASy - ENZYME nomenclature database: 2.8.3.13
BRENDA, the Enzyme Database: 2.8.3.13
CAS: 80237-90-7

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