KEGG   ENZYME: 2.8.3.22
Entry
EC 2.8.3.22                 Enzyme                                 
Name
succinyl-CoA---L-malate CoA-transferase;
SmtAB
Class
Transferases;
Transferring sulfur-containing groups;
CoA-transferases
Sysname
succinyl-CoA:(S)-malate CoA-transferase
Reaction(IUBMB)
(1) succinyl-CoA + (S)-malate = succinate + (S)-malyl-CoA [RN:R00406];
(2) succinyl-CoA + (S)-citramalate = succinate + (S)-citramalyl-CoA [RN:R03154]
Reaction(KEGG)
R00406 R03154
Substrate
succinyl-CoA [CPD:C00091];
(S)-malate [CPD:C00149];
(S)-citramalate [CPD:C02614]
Product
succinate [CPD:C00042];
(S)-malyl-CoA [CPD:C04348];
(S)-citramalyl-CoA [CPD:C01011]
Comment
The enzyme, purified from the bacterium Chloroflexus aurantiacus, can also accept itaconate as acceptor, with lower efficiency. It is part of the 3-hydroxypropanoate cycle for carbon assimilation.
History
EC 2.8.3.22 created 2014
Pathway
ec00660  C5-Branched dibasic acid metabolism
ec00720  Carbon fixation pathways in prokaryotes
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K14471  succinyl-CoA:(S)-malate CoA-transferase subunit A
K14472  succinyl-CoA:(S)-malate CoA-transferase subunit B
K18289  itaconate CoA-transferase
Genes
PGELG71_13505
MSEPCEP49_03355
PAEPA0882
PAEVN297_910
PAEIN296_910
PAUPA14_52870
PAPPSPA7_4632
PAGPLES_44341
PAFPAM18_4157
PNCNCGM2_1660
PAEBNCGM1900_1840
PDKPADK2_21290
PSGG655_20940
PRPM062_04300
PAEPPA1S_22030
PAERPA1R_gp4405
PAEMU769_21400
PAELT223_22665
PAESSCV20265_4642
PAEUBN889_00919
PAEGAI22_11910
PAECM802_906
PAEOM801_910
PMKMDS_3404
PPSEBN5_1316
PCQPcP3B5_31090(frc_3)
PMUIG4G71_15730
PPAAB7D75_20860
PPWPputW619_3048
PPUNPP4_26590
PFVPsefu_2657
PSBPsyr_2175
PFLPFL_2650
PPRCPFLCHA0_c27170
PPROPPC_2699
PFSPFLU_3473
PFCPflA506_2555
PFBVO64_0586
PVRPverR02_17210
PAZOAYR47_23815
PRXHRH33_17865
PFWPF1751_v1c29040
PFFPFLUOLIPICF721665 PFLUOLIPICF722970
PFXA7318_12070
PLULFOB45_04010
PPUUPputUW4_03339
PDRH681_12260
PSKU771_18550
PCHEY04_12160
PCZPCL1606_35340
PCPJM49_17710
PRHLT40_06390
PPVNJ69_15105
PSESPSCI_4461
PSEMTO66_12955
PKRAYO71_15490
PSILPMA3_18310
PYMAK972_2539
PALLUYA_16450
PGGFX982_03220
PPSHG5J76_13805
PSEJHNQ25_09090
PVKEPZ47_18730
PKHJLK41_17670
PTYJWV26_02650
PMAOPMYSY11_1936
PVWHU752_018360
PSAMHU731_001150
PPRGHU725_012655
PFAKKSS94_12305
PWYHU734_004500
PTAENCTC10697_01931(frc_3)
PCAVD3880_17720
PPHNHU825_16710
PIZLAB08_R18840
PPEGKUA23_16510
PSAPST_1697
PSZPSTAB_1607
PSRPSTAA_1727
PSCA458_12220
PSJPSJM300_06625
PSHPsest_2666
PSTUUIB01_13485
PSTTCH92_08225
PSEDDM292_11080
PCHLLLJ08_12790
PBMCL52_10775
PKGLW136_09785
SDEGGOM96_03875
PBAUOS670_05755
MARIACP86_19610
AEIAOY20_13440
AUGURS_0099
HALCEY643_14925
LLG44548918_02119(frc)
KUSB9G99_08665
KMAB9H00_06165
ADIB5T_02015
AXEP40_09635
APACS7S_06585
SDFACG33_08150
GPBHDN1F_13710
PTESJQU52_08495
RPJN234_09425 N234_12060 N234_24310 N234_29250
REHH16_A2423(h16_A2423) H16_B0682(h16_B0682) H16_B2114(h16_B2114)
CNCCNE_2c06340 CNE_2c17690 CNE_2c20670 CNE_BB1p09810 CNE_BB1p10130
CUHBJN34_24705 BJN34_33170
REUReut_B3541
RMERmet_3809 Rmet_3834
CTIRALTA_B0533
CBWRR42_s3311
CGDCR3_0428(caiB)
CCUPBKK81_18875 BKK81_23355 BKK81_30855 BKK81_32485
CUPBKK80_23065 BKK80_23830 BKK80_25500 BKK80_32960
CUUBKK79_23840 BKK79_28340 BKK79_29115 BKK79_31375
CPAUEHF44_20610
COXE0W60_08370 E0W60_17865 E0W60_33280
CCAMM5D45_27435
CCAXKZ686_06365
BTDBTI_2434
BOKDM82_900
BOCBG90_35
BUUWS70_10455
BHGI6G56_08975
BVIBcep1808_5397
BVEAK36_3487
BURBcep18194_C7301
BCMBcenmc03_6653
BCHBcen2424_6173
BCJBCAS0021
BCENDM39_6414
BCEWDM40_5519
BCEOI35_7020
BAMBamb_6269
BACBamMC406_5973
BMKDM80_1411
BCEDDM42_6392
BCONNL30_35115
BUBBW23_6275
BPSLWS57_16950
BMECWJ16_18910
BSTGWT74_17815
BSTLBBJ41_37995
BARINLX30_37335
BGDbgla_1g16800
BGOBM43_2915
BYIBYI23_D006000
BUEBRPE67_DCDS07800
BULBW21_2401
BGPBGL_1c14820 BGL_2c16880
BPLAbpln_1g14520 bpln_2g17550
BUDAQ610_11360
BUMAXG89_23885 AXG89_28805
BXBDR64_4916 DR64_7788
BPHBphy_4945
BGEBC1002_5323 BC1002_5360
BPYBphyt_6602
BFNOI25_5772 OI25_7334 OI25_7352
BCAIK788_0001676
PSPWBJG93_20450
PARABTO02_26500
PHSC2L64_38445
PTERC2L65_34440
PMEGFNZ07_05315
PTROG5S35_27055 G5S35_34880
PGISI6I06_17980
PACPFAZ97_08805
PACSFAZ98_23735 FAZ98_25510
PEWKZJ38_29055 KZJ38_33150
PDIOPDMSB3_0489.1
PNUPnuc_1389
PDQCL55_00012960
PTRPDCO17_07265
PANIDCO16_07240
PCOSC2747_06630
PPKU875_11355
PPNODA70_03750
PPNMLV28_02565
PRBX636_23350
PPULRO07_21515
PSPUNA29_15815
PAPISG18_20340
POXMB84_17150
PTXABW99_01570 ABW99_18560
PFGAB870_22905
PNRAT302_11890
PFIBPI93_015235
PCOMNTU39_14195
PLGNCTC10937_02758(frc_1)
BPARBN117_0346
BPABPP0349 BPP3644
BBHBN112_3062 BN112_4324
BBRBB0352 BB4079
BBMBN115_0337 BN115_3768
BBXBBS798_0347 BBS798_3872
BPTBpet0819 Bpet4777
BHOD560_1019
BHMD558_1005
BHZACR54_03834(frc_9)
BTRMSAMEA390648700266(frc_3) SAMEA390648700435(frc_4)
BBROBAU06_00065
BFZBAU07_00040
BPDZBBN53_03950
BOHAKI39_00035 AKI39_05275
BGMCAL15_19450
AXYAXYL_00900 AXYL_02637
AXONH44784_012411
AXNAX27061_0916
AXXERS451415_00903(frc_3)
ADTAPT56_04805
AISBUW96_21190
ASWCVS48_01855
ACHRC2U31_09195
ACHBDVB37_04000
ADYHLG70_17355
ACHOH4P35_04020
TEQTEQUI_0590
TEAKUI_1573
TEGKUK_0904
TASTASI_1544
TATKUM_1149
PUTPT7_0056
PUSCKA81_09515
AKATKWG_24825
AMIMMIM_c40130
BOZDBV39_17795
OURCEQ07_11005
OUEI6G29_06910
PIGEGT29_18060
PACRFXN63_04135
PARKLSG25_07865
RFRRfer_3485
RHYRD110_23570
RHFEUB48_08790
POLBpro_0582 Bpro_4555
PNAPnap_2141 Pnap_3809
PVACHC248_01528(yfdE)
AJSAjs_0117
ACIDCBP33_00615
ACIPCBP36_00665
ACINCBP34_00625
ACISCBP35_18290
AMONH9L24_14965
ARADKI609_00910
VEIVeis_4805
DACDaci_0010 Daci_0199
DELDelCs14_0012 DelCs14_0202
DTSBI380_21815 BI380_22750
DHKBO996_01990 BO996_02940
DLAI6G47_21760 I6G47_22715
VAPVapar_2027
VPEVarpa_3861
VPDVAPA_1c21480 VAPA_2c05860
VBOCKY39_21085
VAMC4F17_02330
CTTCtCNB1_0223
CTESO987_01130
CKEB5M06_05525
CSERCCO03_14430
COFFOZ74_10395
CAQTKAQ61_17030
CODOLAD35_00915
ADNAlide_0161 Alide_0200 Alide_0312 Alide_2926
ADKAlide2_0150 Alide2_0189 Alide2_0259 Alide2_1521
RTARta_16640
LIHL63ED372_02959(frc_3)
HYRBSY239_2818
HYLLPB072_14635
HPSEHPF_12655(frc1)
HYNF9K07_24615 F9K07_27750
HTNKI616_13925
DPYBA022_14260
DIHG7047_08600 G7047_24175
DAERH9K75_13290
DRGH9K76_23190
DIADtpsy_0135
MELAC6568_08420
MJELVC68_00520
PBHAAW51_3180
ATERMW290_10330
HSEHsero_2797(caiB)
HSZACP92_14035
HHTF506_15995
HRBHrubri_2848(caiB)
HEEhmeg3_12905
HHFE2K99_14670
HFRG5S34_14660
MASWAM586_26005
MFLAGO485_26090
NOKFAY22_02480
GLCJQN73_04410
LCHLcho_2416
XYKGT347_01935 GT347_12550
ARESIWH25_16375
RBUPG1C_11180
OTROTERR_27810
APETToN1_04130 ToN1_05480
AZAAZKH_1922
AZRCJ010_16455 CJ010_17070
AZQG3580_09940
ACOMCEW83_02960
APPCAP2UW1_1660 CAP2UW1_2505 CAP2UW1_2506
BPRCD521_1179 D521_1582
CCCG157_06425
CCQN149_0441
CCFYSQ_07645
CCYYSS_02010
CCOIYSU_06655
CCOFVC76_02325(frc)
CCOOATE51_03326(frc)
MCIMesci_6212
MOPMesop_2796
NIYFQ775_07245
SFHSFHH103_02515
RLTRleg2_6122
BMELDK63_2182
BMIBMEA_B0167
BMZBM28_B0160
BMGBM590_B0160
BMWBMNI_II0158
BMEEDK62_2094
BMBBruAb2_0161
BMCBAbS19_II01540
BAABAA13334_II00473
BABODK55_2160
BABRDO74_2287
BABTDK49_2268
BABBDK48_2532
BABUDK53_2975
BABSDK51_2463
BABCDO78_3182
BSIBS1330_II0163
BSFBSS2_II0157
BSUIBSSP1_II0126
BSUPBSPT1_II0127
BSUVBSPT2_II0127
BSUCBSSP2_II0128
BMTBSUIS_B0169
BSZDK67_2187
BSVBSVBI22_B0162
BSWIY71_09920 IY71_11900
BSGIY72_09660 IY72_11440
BOVBOV_A0147
BCSBCAN_B0166
BSKBCA52141_II0978
BOLBCOUA_II0166
BCARDK60_3042
BCASDA85_11295
BMRBMI_II163
BPPBPI_II163
BPVDK65_2306
BCETV910_201038
BCEEV568_201210
BVLBF3285c2_0642
BRUBFS01_11175
BRJBKD03_01605
BIOBR141012304_20026
OPSA8A54_19020
BJUBJ6T_21460
BJPRN69_10510
BRABRADO1441 BRADO4810
BBTBBta_6664
BRSS23_58700
BRCBCCGELA001_06955 BCCGELA001_07445
BRADBF49_2776 BF49_2900
BROBRAD285_0943
BOTCIT37_18290 CIT37_18885
BRQCIT40_04565 CIT40_05120
BGQX265_30465 X265_31255 X265_39750
BGZXH91_28925 XH91_34305
BSYMCIT39_02905 CIT39_03730
BBETF8237_09015
BARHWN72_41400
BVZBRAD3257_1395
BDGLPJ38_11060 LPJ38_11610
BBANJ4G43_011230
RPBRPB_3936
RPTRpal_1801
VGOGJW-30_1_00417(frc_2)
TRBHB776_15070
SNOSnov_3517
STARG3545_21890
MNOMnod_6787
MAQUMaq22A_c12690(caiB)
MEEDA075_02045
METIDK427_09380
MTEADK419_03800
BIDBind_2536
MLGCWB41_06945
CHELAL346_22470
RHZRHPLAN_69680
PSINCAK95_10205
SPSESULPSESMR1_04146(yfdE)
RIDRIdsm_03587(frc_6)
MARUFIU81_05545(bbsF)
TGLHFZ77_15570
PYEA6J80_20580
PARUCYR75_12705
RHMB5V46_07920
SEDIEBB79_09215
HMLHmaOT1_14845
PSEBEOK75_18780
MONG8E03_02675 G8E03_07200
POZI0K15_05895
PGVSL003B_0528
NOGGKE62_16260
SPHPLH20_19545
SMAZLH19_26470
SPHOC3E99_12880
SPHDHY78_30015
RDICMV14_18660
SECHB18_16060
SPHTK426_18730
SMICSmB9_16430
TFVIDJ81_06825
ERYCP97_12705
ACRAcry_2578
AMVACMV_29030
RGIRGI145_21790
ABSAZOBR_p150095 AZOBR_p330132
ABQABAZ39_15015 ABAZ39_20990
ABFAMK58_14530
AZTTSH58p_23065 TSH58p_25140
AARED3093_19940
SKTIGS68_05130
SMUCJL100_022625
SROEJL101_021275
PARHI5S86_16860
LEXLen3610_00570
PBUTDTO10_25745
RUEDT065_03740
SALEEPH95_03510
BCHSJNE38_07810
PLLI858_009895
PFAEAJGP001_14920
MAVMAV_1892 MAV_2651
MITOCO_14320
MIAOCU_14780
MIROCQ_28570
MMANMMAN_43170
MSAMycsm_04530
MMCMmcs_3742
MKMMkms_3815
MJLMjls_3754 Mjls_4229
MYVG155_20715
MYEAB431_21780
MGOAFA91_16440
MDXBTO20_10515
MGROFZ046_24485
MXEMYXE_08730 MYXE_10790
MNVMNVI_09770
MNMMNVM_10800
MCOOMCOO_24280
MHEKJMUB5695_00851 JMUB5695_00994
MGAUMGALJ_25900
MBRDMBRA_23580 MBRA_56850
MDFK0O62_00540 K0O62_20630
MHOLK3U96_08345
MHERK3U94_04085
MSENK3U95_09205
MPAEK0O64_21540
MVMMJO54_04070
MRFMJO55_19015
MPAAMKK62_03770
MCROMI149_21885
MSMMSMEG_1992 MSMEG_4046 MSMEG_4834
MSGMSMEI_1948 MSMEI_3951 MSMEI_4710
MSBLJ00_09940 LJ00_20085 LJ00_23910
MSNLI99_09940 LI99_20090 LI99_23915
MSHLI98_09940 LI98_20095 LI98_23920
MVAMvan_4208
MGIMflv_2443
MSPMspyr1_18690
MCBMycch_3647
MNED174_19900
MYNMyAD_19525
MFTXA26_42260
MPHLMPHLCCUG_03775(frc_4)
MVQMYVA_0214 MYVA_4010
MLLB1R94_08270
MRHMycrhN_3964
MTHN4412656_03069(frc_11)
MHASMHAS_02595(smtB_2)
MDUMDUV_04610 MDUV_29930
MCHTMCHIJ_08770 MCHIJ_28880
MDRMDOR_26970
MAUUNCTC10437_03952(frc_10)
MMAGMMAD_39380 MMAD_55320
MMORMMOR_23430
MFXMFAL_00860
MAICMAIC_38570
MIJMINS_35900
MALVMALV_21110 MALV_52710
MTYMTOK_12000
MPSCMPSYJ_26150
MARZMARA_57980
MGADMGAD_56680
MHEVMHEL_05620
MSARMSAR_30800
MANYMANY_22130 MANY_24250
MAUBMAUB_13330 MAUB_47390
MPOFMPOR_43130
MPHUMPHO_21690
MMUCC1S78_007385 C1S78_018530
MMATMMAGJ_01010
MBOKMBOE_31550 MBOE_58470
MFGK6L26_11025
MSEIMSEDJ_50830
MFLVNCTC10271_01513(frc_6)
MCEEMCEL_47970
MMONEWR22_19290
MJDJDM601_0736
MTER4434518_00718(frc_3)
MHIBMHIB_02430
MPAKMIU77_10990
CPUCPFRC_05855
CPLCp3995_1186
CPGCP316_06005
CPPCpP54B96_1182
CPKCP1002_07290
CPQCPC231_05860
CPXCPI19_05660
CPZCpPAT10_1158
CORCp267_1214
COPCP31_06235
CODCp106_1143
COSCp4202_1152
COICPCIP5297_06020
COECP258_06020
COUCP162_05275
CPSECPTA_01735
CPSUCPTB_02028
CPSFCPTC_01726
NNONONO_c28330 NONO_c43090
NSLBOX37_12945
NWLNWFMUON74_28110
NGPLTT66_34255
RERRER_52090
REYO5Y_24645
REBXU06_25065
RQIC1M55_26265
ROPROP_28170 ROP_28880 ROP_31500 ROP_71070
ROAPd630_LPD04643 Pd630_LPD07245 Pd630_LPD07435 Pd630_LPD07620 Pd630_LPD07626
RHODAOT96_06075
RRT4535765_04348(frc_10)
RCRNCTC10994_03025(frc_4)
RTMG4H71_12145
RKOJWS14_16175
RGOKYT97_14075
ROZCBI38_05345 CBI38_16460
RPSKJWS13_28795
GOQACH46_00580
GOCCXX93_02665
GITC6V83_01015
GRUGCWB2_12120(frc5)
GOMD7316_02162(yfdE_2) D7316_02375(yfdE_3)
GAMGII34_05115 GII34_19900 GII34_22320
GPDGII33_02900 GII33_04565
GJIH1R19_01490
SPINKV203_05330 KV203_08160 KV203_09940
SCOSCO3130(SCE66.09)
SALBXNR_0226
SGBWQO_06375
SCBSCAB_72481
SVLStrvi_4264
SHYSHJG_3170
SHOSHJGH_2934
SRCM271_04035 M271_41095 M271_49655 M271_50580
SSOII1A49_00485
SFASfla_1417
SBHSBI_00762 SBI_01684
SVESVEN_1337
SDVBN159_6844
SALSSLNWT_6159
STRPF750_5463
SLVSLIV_22030
STREGZL_01187
SLCSL103_16240
SAMBSAM23877_3180
SPRISPRI_5820
SRWTUE45_02185(frc_1)
SPAVSpa2297_13590
SGSAVL59_35295
SKYD0C37_02530
SALWCP975_04635
SGMGCM10017557_75030
SCADDN051_07860
SNRSNOUR_05055
SALUDC74_7458
SALLSAZ_38515
STRDNI25_23140
SNWBBN63_24175
SAUOBV401_00740
SSIAA7J05_30430
SVUB1H20_05555
SPUNBFF78_32855
SGVB1H19_06025
SLAUSLA_0538
SALFSMD44_01319(frc)
SALJSMD11_0726
STROSTRMOE7_03415
SFKKY5_1012
SGEDWG14_00638(yfdE)
SRJSRO_5753
SLKSLUN_08070
STIRDDW44_02625
SKACP970_37845
SRKFGW37_28325
SFICEIZ62_01235 EIZ62_26570
SGALCP966_07140
SSPODDQ41_02065
SFYGFH48_08995
SGFHEP81_06057
SBYH7H31_01550
SCINCP977_07645 CP977_30975
SPACB1H29_21815
SGXH4W23_08585
SSPBCP982_07025
STUIGCM10017668_62570
SDWK7C20_36115
SGJIAG43_24615
SHKJ2N69_04540
SANUK7396_00905
SINEKI385_04045
SDURM4V62_35655
SRUGF0345_25990
YIALO772_06010
MIOAOA12_04790
AMINAUMI_115650
AUWAURUGA1_01429(frc)
SALCC2138_12290
SALDFVA74_01340
ARTPE5206_12370
TEHGKE56_14400
PEIH9L10_10390
BLINBLSMQ_0276
BRIFDF13_04885
NOYEXE57_12390
NMESH9L09_05805
NAQUENKNEFLB_04395(uctC_2)
AEFGEV26_04005 GEV26_09330
NDANdas_1193
FREFranean1_4296
FRIFraEuI1c_4067 FraEuI1c_5266
FALFRAAL3412
BSDBLASA_3444
SENSACE_4588
SACGFDZ84_18305
AMNRAM_23535
AMMAMES_4566
AMZB737_4566
AOIAORI_4919(mcr)
AJAAJAP_14940
AMYCCU254_24250
AMYBBKN51_17000
AABA4R43_21195
AMYYYIM_08245(frc2)
AROONQK81_42320
ATHML1857_22750
PDXPsed_1966 Psed_4111 Psed_4214
PSEAWY02_08930
PSEEFRP1_19745
PSEHXF36_05585
PSEQAD006_27160
PECQAD017_06755
PHHAFB00_03510
PAUTPdca_48960 Pdca_66680
PBROHOP40_18950 HOP40_23080
PPELH6H00_21750
SSYIEKG83_06775
KALKALB_1579 KALB_5714
KPHYAOZ06_41900
LEDBBK82_04605
ALOCRK55392
SACEGIY23_13735
ACTNL083_5712
PLKCIK06_24300
PFLAPflav_047640
PSUUPsuf_071660
EKEEK0264_05060
RXYRxyl_2734
RRDRradSPS_1692
RUBGBA63_03970
RRSRoseRS_4175 RoseRS_4176
RCARcas_0909 Rcas_0910
CAUCaur_0178 Caur_0179
CHLChy400_0190 Chy400_0191
CAGCagg_1330 Cagg_1331
HAUHaur_2263
STISthe_1793
GGRHKW67_06660 HKW67_06665
NMGNmag_3456
NPENatpe_1336
HJTDVR14_15855
NAGAArcMg_4136
NBGDV706_20330
NASGCU68_20755
 » show all
Reference
1  [PMID:16547052]
  Authors
Friedmann S, Steindorf A, Alber BE, Fuchs G
  Title
Properties of succinyl-coenzyme A:L-malate coenzyme A transferase and its role in the autotrophic 3-hydroxypropionate cycle of Chloroflexus aurantiacus.
  Journal
J Bacteriol 188:2646-55 (2006)
DOI:10.1128/JB.188.7.2646-2655.2006
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.8.3.22
IUBMB Enzyme Nomenclature: 2.8.3.22
ExPASy - ENZYME nomenclature database: 2.8.3.22
BRENDA, the Enzyme Database: 2.8.3.22

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