KEGG   ENZYME: 3.1.1.22
Entry
EC 3.1.1.22                 Enzyme                                 
Name
hydroxybutyrate-dimer hydrolase;
D-(-)-3-hydroxybutyrate-dimer hydrolase
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
Sysname
(R)-3-((R)-3-hydroxybutanoyloxy)butanoate hydroxybutanoylhydrolase
Reaction(IUBMB)
(R)-3-((R)-3-hydroxybutanoyloxy)butanoate + H2O = 2 (R)-3-hydroxybutanoate [RN:R00048]
Reaction(KEGG)
R00048
Substrate
(R)-3-((R)-3-hydroxybutanoyloxy)butanoate [CPD:C04546];
H2O [CPD:C00001]
Product
(R)-3-hydroxybutanoate [CPD:C01089]
History
EC 3.1.1.22 created 1972
Pathway
ec00650  Butanoate metabolism
ec01100  Metabolic pathways
Orthology
K07518  hydroxybutyrate-dimer hydrolase
Genes
SACZAOT14_27150(phaZ2)
STEKAXG53_12210
STEMCLM74_11365
SINCDAIF1_22070(phaZ2)
PSUWWQ53_01110
PMEXH4W19_06590
PJPLAG73_05285
PDDMNQ95_00070
LABLA76x_2936
LAQGLA29479_253
LCPLC55x_2386
LGULG3211_2850
LEZGLE_2861
LEMLEN_2170
LMBC9I47_1386
LYTDWG18_05225
LUEDCD74_03510
LYJFKV23_06985
LSOLGOY17_07345
LSXH8B22_06795
LAREHIV01_003335
LHXLYSHEL_24960
LCASLYSCAS_24960
LCICINQ41_08100
LAVIINQ42_07560
LUSE5843_14540
LUGFPZ22_12945
THESFHQ07_01745
THEHG7079_08455
TCNH9L16_13615
TBVH9L17_01415
XBCELE36_11710
RHDR2APBS1_1536
RTHLRK53_09410
DJICH75_12505
DJAHY57_16195
DTXATSB10_02030
DYEEO087_05065
DCSISN74_06025
DTLH8F01_02275
DKOI596_14
LRZBJI69_15720
LPYFIV34_08110
XBAC7S18_17910
RBDALSL_1632
VNAPN96_21190
VEJVEJY3_20446
PLULFOB45_02940 FOB45_03300
MAQMaqu_0083
MHCMARHY0070
MADHP15_3792
MSRAU15_04470
MARIACP86_09695
MARAD0851_12150
SAGAM5M_03960
TIGTHII_3784
BLEPAL038_01045
WMAWM2015_2321
GAIIMCC3135_14790
HAKKO116_03014
NCUF0U83_07895
GAPGAPWK_0910
FPPFPB0191_00792
ORBIPMB12_05785
IFLC1H71_19490
RSORSc1334
RSCRCFBP_20092(phaY)
RSLRPSI07_2033(phaY)
RSNRSPO_c02022
RSMCMR15_20545(phaY)
RSEF504_1366
RSYRSUY_17720
RPIRpic_1209
RPFRpic12D_1270
RPJN234_13100
RMNTK49_10820
RINACS15_2033(phaZ2)
RPUCDC45_06875
RSGJK151_10985
REHH16_A2251(phaY1)
CNCCNE_1c21560(phaZ2)
CUHBJN34_11485
REUReut_A1981
RMERmet_1960(phaY)
CTIRALTA_A1796(phaY1)
CBWRR42_m2523
CGDCR3_1108
CCUPBKK81_25520
CUPBKK80_30880
CUUBKK79_21770
CPAUEHF44_12800
COXE0W60_20730
BMABMA2028
BMVBMASAVP1_A0886
BMLBMA10229_A2720
BMNBMA10247_1890
BMALDM55_2423(phaZ2)
BMAEDM78_2599(phaZ2)
BMAQDM76_2408(phaZ2)
BMAIDM57_820
BMAFDM51_1690(phaZ2)
BMAZBM44_1320(phaZ2)
BMABBM45_882
BPSBPSL2716
BPMBURPS1710b_3200
BPLBURPS1106A_3184
BPDBURPS668_3147
BPRGBP346_A3326
BPSEBDL_2730(phaZ2)
BPSMBBQ_596(phaZ2)
BPSUBBN_724(phaZ2)
BPSDBBX_1129(phaZ2)
BPZBP1026B_I0599
BPQBPC006_I3225
BPKBBK_2217(phaZ2)
BPSHDR55_1803(phaZ2)
BPSABBU_2848(phaZ2)
BPSOX996_1444(phaZ2)
BUTX994_3443(phaZ2)
BTEBTH_I1420
BTQBTQ_2512(phaZ2)
BTJBTJ_3182(phaZ2)
BTZBTL_1113(phaZ2)
BTDBTI_884(phaZ2)
BTVBTHA_1205(phaZ2)
BTHEBTN_275(phaZ2)
BTHMBTRA_1321(phaZ2)
BTHADR62_441
BTHLBG87_1310(phaZ2)
BOKDM82_2381(phaZ2)
BOCBG90_2352(phaZ2)
BUUWS70_13845
BSAVWS86_04685
BVIBcep1808_0779
BVEAK36_27(phaZ2)
BURBcep18194_A3932
BCNBcen_0357
BCHBcen2424_0840
BCMBcenmc03_0812
BCJBCAL3165
BCENDM39_651(phaZ2)
BCEWDM40_1505(phaZ2)
BCEOI35_0697
BAMBamb_0719
BACBamMC406_0736
BMJBMULJ_00694
BMUBmul_2544
BMKDM80_844(phaZ2)
BMULNP80_855(phaZ2)
BCTGEM_2689
BCEDDM42_990(phaZ2)
BCEPAPZ15_07845
BDLAK34_2333(phaZ2)
BPYRABD05_09815
BCONNL30_11590
BUBBW23_897(phaZ2)
BDFWI26_03700
BLATWK25_03915
BTEIWS51_14475
BSEMWJ12_03805
BPSLWS57_21610
BMECWJ16_03840
BSTGWT74_04120
BSTLBBJ41_07970
BANNJFN94_03980
BUGBC1001_5213
BGFBC1003_4271
BYIBYI23_A021060
BUKMYA_0735
BUEBRPE67_ACDS21760
BULBW21_979(phaZ2)
BUQAC233_23960
BUDAQ610_04300
BUMAXG89_02600
BUIAX768_12315
BURKDM992_17405
BXEBxe_B2223
BXBDR64_4554(phaZ2)
BPHBphy_5886
BGEBC1002_1604
BPXBUPH_05869
BPYBphyt_5988
BCAIK788_0004956
PARABTO02_16920
PARBCJU94_32465
PTERC2L65_12455
PGPCUJ91_19600
PCJCUJ87_30280
PTSCUJ90_26980
PGISI6I06_19325
PACPFAZ97_29210
PEWKZJ38_05295
PDIOPDMSB3_0875.1
CABASBC2_29300(phaZ2)
BUOBRPE64_ACDS22210
RFRRfer_3022
RHYRD110_16910
POLBpro_4732
PNAPnap_3987
POSDT070_07415
POOF7R28_02005
AAVAave_3005
AAAAcav_2292
ACKC380_16375
ACIDCBP33_06710
ACIPCBP36_07280
ACINCBP34_06610
ACISCBP35_11655
ACIOEAG14_07530
AMONH9L24_00345
DACDaci_2556
DELDelCs14_4099
DTSBI380_11485
DHKBO996_12045
DLAI6G47_11420
CTTCtCNB1_1224
CODOLAD35_13220
ADNAlide_1916
ADKAlide2_2115
RTARta_15680
DPYBA022_02925
DIHG7047_06285
DAERH9K75_21805
DRGH9K76_14960
DIADtpsy_2060
SIMPC6571_01330
MELMC7H73_14385
MELAC6568_04595
KIAG8A07_00975
JAGGJA_5269(phaZ2)
JABVN23_05265
JAZYQ44_26520
JALBZG29_01515
JSVCNX70_01625
JASFJQ89_18655
JLVG3257_01495
MNRACZ75_18960
MASZC9I28_01930
MASYDPH57_20025
MALIEYF70_28680
MUMFCL38_20965
MFLAGO485_16105
MPLIE1742_15900
DUGHH213_11310
NOKFAY22_09810
LCHLcho_4280
RGERGE_43270
RBNRBXJA2T_04513
PKTAT984_01170
RGUA4W93_04170
SNNEWH46_05015
XYKGT347_05230 GT347_24595
IDCLRM40_14315
ATERMW290_30000
URUDSM104443_03848
UPLDSM104440_03398
AZOazo3634
AOAdqs_3779
AZAAZKH_3314
AZRCJ010_12290
AZQG3580_07875
BEBABWI17_07775
DMMdnm_083990
CFUSCYFUS_008232
METM446_0749
MOCBB934_26055 BB934_42265
BIDBind_3542
CAKCaul_3290
SKTIGS68_10710
SMUCJL100_016160
SROEJL101_014945
ECOGFIV45_06300
SRCM271_06830
SMALSMALA_7055
SSOII1A49_39035
SBHSBI_02108
SAUOBV401_38905
SFEUIM697_26895
PLPPle7327_3963
 » show all
Reference
1  [PMID:4954074]
  Authors
Delafield FP, Cooksey KE, Doudoroff M.
  Title
beta-Hydroxybutyric dehydrogenase and dimer hydrolase of Pseudomonas lemoignei.
  Journal
J Biol Chem 240:4023-8 (1965)
Other DBs
ExplorEnz - The Enzyme Database: 3.1.1.22
IUBMB Enzyme Nomenclature: 3.1.1.22
ExPASy - ENZYME nomenclature database: 3.1.1.22
BRENDA, the Enzyme Database: 3.1.1.22
CAS: 37278-37-8

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