| Entry |
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| Name |
guanidinobutyrase;
gamma-guanidobutyrase;
4-guanidinobutyrate amidinobutyrase;
gamma-guanidinobutyrate amidinohydrolase;
G-Base;
GBH;
guanidinobutyrate ureahydrolase
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| Class |
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amidines
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| Sysname |
4-guanidinobutanoate amidinohydrolase
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| Reaction(IUBMB) |
4-guanidinobutanoate + H2O = 4-aminobutanoate + urea [RN: R01990]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
Requires Mn2+. Also acts, very slowly, on 5-guanidinopentanoate and 6-guanidinohexanoate.
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| History |
EC 3.5.3.7 created 1972
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| Pathway |
| ec00330 | Arginine and proline metabolism |
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| Orthology |
| K25365 | guanidinobutyrase / D-arginase |
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| Genes |
» show all
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| Reference |
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| Authors |
Mora J, Tarrab R, Martuscelli J, Soberon G. |
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| Title |
Characteristics of arginases from ureotelic and non-ureotelic animals. |
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| Journal |
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| Reference |
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| Authors |
Nguyen Van Thoai, Thome-Beau F, Olomucki A. |
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| Title |
[Induction and specificity of enzymes of the new catabolic arginine pathway] |
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| Journal |
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| Reference |
3 |
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| Authors |
Yorifuji, T., Kato, M., Kobayashi, T., Ozaki, S. and Ueno, S. |
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| Title |
4-Guanidinobutyrate amidinohydrolase from Pseudomonas sp ATCC 14676: purification to homogeneity and properties. |
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| Journal |
Agric Biol Chem 44:1127-1134 (1980) |
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| Reference |
4 |
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| Authors |
Yorifuji, T., Kobayashi, T., Tabuchi, A., Shiritani, Y. and Yonaha, K. |
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| Title |
Distribution of amidinohydrolases among Pseudomonas and comparative studies of some purified enzymes by one-dimensional peptide mapping. |
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| Journal |
Agric Biol Chem 47:2825-2830 (1983) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 3.5.3.7 |
| ExPASy - ENZYME nomenclature database: | 3.5.3.7 |
| BRENDA, the Enzyme Database: | 3.5.3.7 |
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