KEGG   ENZYME: 3.6.1.67
Entry
EC 3.6.1.67                 Enzyme                                 
Name
dihydroneopterin triphosphate diphosphatase;
folQ (gene name);
nudB (gene name);
NUDT1 (gene name);
dihydroneopterin triphosphate pyrophosphohydrolase
Class
Hydrolases;
Acting on acid anhydrides;
In phosphorus-containing anhydrides
Sysname
7,8-dihydroneopterin 3'-triphosphate diphosphohydrolase
Reaction(IUBMB)
7,8-dihydroneopterin 3'-triphosphate + H2O = 7,8-dihydroneopterin 3'-phosphate + diphosphate [RN:R04638]
Reaction(KEGG)
R04638
Substrate
7,8-dihydroneopterin 3'-triphosphate [CPD:C04895];
H2O [CPD:C00001]
Product
7,8-dihydroneopterin 3'-phosphate [CPD:C05925];
diphosphate [CPD:C00013]
Comment
The enzyme participates in a folate biosynthesis pathway, which is found in bacteria, fungi, and plants. Requires Mg2+.
History
EC 3.6.1.67 created 2014
Pathway
ec00790  Folate biosynthesis
ec01100  Metabolic pathways
Orthology
K08310  dihydroneopterin triphosphate diphosphatase
K19965  dihydroneopterin triphosphate pyrophosphohydrolase
Genes
ECOb1865(nudB)
ECJJW1854(nudB)
ECDECDH10B_2006(nudB)
EBWBWG_1679(nudB)
ECOKECMDS42_1542(nudB)
ECEZ2917
ECSECs_2575(nudB)
ECFECH74115_2601(nudB)
ETWECSP_2439(nudB)
ELXCDCO157_2410(ntpA)
EOIECO111_2387(nudB)
EOJECO26_2717(nudB)
EOHECO103_2055(nudB)
ECOOECRM13514_2374(ntpA)
ECOHECRM13516_2277(ntpA)
ESLO3K_10605(nudB)
ESOO3O_15020(nudB)
ESMO3M_10580(nudB)
ECKEC55989_2044(nudB)
ECGE2348C_1990(nudB)
EOKG2583_2317(nudB)
ELRECO55CA74_11155(nudB)
ELHETEC_1898
ECWEcE24377A_2095(nudB)
EUNUMNK88_2337
ECPECP_1809
ENAECNA114_1929(ntpA)
ECOSEC958_2088(ntpA)
ECVAPECO1_915(ntpA)
ECOAAPECO78_13140(nudB)
ECXEcHS_A1958(nudB)
ECMEcSMS35_1321(nudB)
ECYECSE_2041
ECRECIAI1_1952(nudB)
ECQECED1_2070(nudB)
EUMECUMN_2163(nudB)
ECTECIAI39_1184(nudB)
EOCCE10_2151(nudB)
EBRECB_01836(ntpA)
EBLECD_01836(nudB)
EBEB21_01824(nudB)
EBDECBD_1773
ECIUTI89_C2069(ntpA)
EIHECOK1_1984(nudB)
ECZECS88_1923(nudB)
ECCc2279(ntpA)
ELOEC042_2032(nudB)
ELNNRG857_09350(ntpA)
ESEECSF_1725
ECLEcolC_1767
EKOEKO11_1903
EKFKO11_13370(nudB)
EABECABU_c21270(ntpA)
EDHEcDH1_1775
EDJECDH1ME8569_1811(nudB)
ELUUM146_07825(ntpA)
ELWECW_m2041(nudB)
ELLWFL_10015(nudB)
ELCi14_2095(ntpA)
ELDi02_2095(ntpA)
ELPP12B_c1220(ntpA)
ELFLF82_1529(nudB)
ECOLLY180_09710(nudB)
ECOIECOPMV1_01958(nudB)
ECOJP423_09910(nudB)
EFEEFER_1207(nudB)
EALEAKF1_ch4172(ntpA)
EMAC1192_02920
ESZFEM44_24230(nudB)
STYSTY2108(ntpA)
STTt0977(ntpA)
SEXSTBHUCCB_10480
SENTTY21A_04980(ntpA)
STMSTM1900(ntpA)
SEOSTM14_2311(ntpA)
SEVSTMMW_18831
SEYSL1344_1835(ntpA)
SEMSTMDT12_C19250(ntpA)
SEJSTMUK_1880(ntpA)
SEBSTM474_1933(nudB)
SEFUMN798_2004(ntpA)
SETUSTU288_05910(nudB)
SETCCFSAN001921_07565(nudB)
SENRSTMDT2_18291(ntpA)
SENDDT104_19161(ntpA)
SENICY43_10025(nudB)
SEENSE451236_15445(nudB)
SPTSPA0969(ntpA)
SEKSSPA0903
SPQSPAB_01264
SEISPC_1813(ntpA)
SECSCH_1908(ntpA)
SEHSeHA_C2114(nudB)
SHBSU5_02511
SENHCFSAN002069_22325(nudB)
SEEHSEEH1578_18805(nudB)
SEESNSL254_A2059(nudB)
SENNSN31241_29990
SEWSeSA_A2054(nudB)
SEASeAg_B1223(nudB)
SENSQ786_05700(nudB)
SEDSeD_A1347(nudB)
SEGSG1152(ntpA)
SELSPUL_1784(ntpA)
SEGASPUCDC_1770(ntpA)
SETSEN1103(ntpA)
SENAAU38_05710(nudB)
SENOAU37_05700(nudB)
SENVAU39_05700(nudB)
SENQAU40_06420(nudB)
SENLIY59_05815(nudB)
SENJCFSAN001992_01930(nudB)
SEECCFSAN002050_15970(nudB)
SEEBSEEB0189_009975(nudB)
SEEPI137_08100(nudB)
SENBBN855_19860(nudB)
SENEIA1_09450(nudB)
SENCSEET0819_16210(nudB)
SESSARI_01048
SBGSBG_1735(ntpA)
SBZA464_1986
SBVN643_08450(nudB)
SALZEOS98_09605
SFLSF1875(ntpA)
SFXS1941(ntpA)
SFVSFV_1867(ntpA)
SFESFxv_2099(nudB)
SFNSFy_2686
SFSSFyv_2746
SFTNCTC1_02030(nudB)
SSNSSON_1276(ntpA)
SBOSBO_1188(ntpA)
SBCSbBS512_E1107(nudB)
SDYSDY_1152(ntpA)
SDZAsd1617_01486
SHQA0259_13450(nudB)
ENCECL_01433
ENLA3UG_13960(nudB)
ECLGEC036_27030
ECLEECNIH2_13495(nudB)
ECLNECNIH4_09250(nudB)
ECLIECNIH5_12980(nudB)
ECLXLI66_13670(nudB)
ECLYLI62_15010(nudB)
ECLZLI64_13085(nudB)
ECLOENC_06300
EHMAB284_12120(nudB)
EXFBFV63_13355
ECLAECNIH3_13025(nudB)
ECLCECR091_12960(nudB)
EAUDI57_05505(nudB)
EKBBFV64_13760
ENOECENHK_13700(nudB)
EECEcWSU1_02789(nudB)
ELGBH714_09700
ECANCWI88_09070
ERNBFV67_13355
ECHGFY206_14740(nudB)
ESHC1N69_13810
ENTEnt638_2433
EASEntas_2571
ENRH650_05060(nudB) H650_07820
ENXNI40_013675(nudB)
ENFAKI40_3583(nudB)
LNICWR52_21470
EBGFAI37_15490(nudB)
ENDA4308_18010(nudB)
ENZG0034_13625(nudB)
ENSHWQ15_21870(nudB)
ENKLOC22_01355(nudB)
EHUD5067_0009285(nudB)
EMORL6Y89_13060(nudB)
ENBELK40_14010
ESAESA_01377
CSKES15_1590(ntpA)
CSZCSSP291_06740(nudB)
CSJCSK29544_02686
CCONAFK62_11610(nudB)
CDMAFK67_12300(nudB)
CSIP262_02306
CMJAFK66_007625(nudB)
CUIAFK65_12000(nudB)
CMWAFK63_06360(nudB)
CTUCTU_25470(nudB)
KPNKPN_02379(ntpA)
KPUKP1_3509(ntpA)
KPMKPHS_34000
KPPA79E_1853
KPHKPNIH24_11585(nudB)
KPZKPNIH27_16410(nudB)
KPVKPNIH29_16900(nudB)
KPWKPNIH30_17215(nudB)
KPYKPNIH31_16315(nudB)
KPGKPNIH32_17110(nudB)
KPCKPNIH10_16665(nudB)
KPQKPR0928_16640(nudB)
KPTVK055_0068(ntpA)
KPOKPN2242_14875(nudB)
KPRKPR_3292(ntpA)
KPJN559_1880
KPID364_12095(nudB)
KPAKPNJ1_02041
KPSKPNJ2_02003
KPXPMK1_04741(nudB)
KPBFH42_07985(nudB)
KPNEKU54_009405(nudB)
KPNULI86_09360(nudB)
KPNKBN49_3485(ntpA)
KVAKvar_1726
KPEKPK_1905(nudB)
KPKA593_01535(nudB)
KVDKR75_25245
KVQSP68_05610
KOXKOX_23940(nudB)
KOEA225_3681
KOYJ415_13685(nudB)
KOMHR38_22245(nudB)
KMIVW41_13335(nudB)
KOKKONIH1_18220(nudB)
KOCAB185_17925(nudB)
KQUAVR78_21020
EAEEAE_22870(nudB)
EARCCG29427
KQVB8P98_10425
KLLBJF97_18120
KLWDA718_10945(nudB)
KARLGL98_09000(nudB)
KGRJJJ10_10850(nudB)
RORRORB6_02850(nudB)
RONTE10_18430(nudB)
RPLNB1209_09290
RAODSD31_09285
RTGNCTC13098_02705(nudB)
REEelectrica_01858(nudB)
CROROD_19061(nudB)
CKOCKO_01096
CFDCFNIH1_20480(nudB)
CBRAA6J81_01775
CWECO701_12740
CYOCD187_09870
CPOTFOB25_21470(nudB)
CFQC2U38_10115
CSEDJY391_09475(nudB)
CAMAF384_09005(nudB)
CAFAL524_13265
CIFAL515_14090
CFARCI104_15380
CIRC2U53_24400
CIEAN232_15285
CPARCUC49_09850
CTELGBC03_15435(nudB)
CITZE4Z61_07720(nudB)
CARSE1B03_16020(nudB)
EBTEBL_c23250(ntpA)
CNTJT31_21525(nudB)
CEMLH23_19365(nudB)
CENLH86_18090(nudB)
CLAPNCTC11466_01749(nudB)
PGELG71_14450(nudB)
ESCEntcl_1926
KLEAO703_12545(nudB)
KSAC813_00980 C813_22635
KORAWR26_10290(nudB)
KRDA3780_13830(nudB)
KCOBWI95_19135
KOTEH164_09400
KPSEIP581_13620(nudB) IP581_16075
KIENCTC12125_00931(nudB)
KASKATP_17540(ntpA)
LAXAPT61_08555(nudB)
LEIC2U54_18990
LEHC3F35_20765
LEEDVA44_09170
LERGNG29_13810(nudB)
LEAGNG26_13780(nudB)
LPNUKQ929_07800(nudB)
LAZA8A57_12955
LEFLJPFL01_2499
LEWDAI21_13685
BUFD8682_04835
BAGEBADSM9389_17440
BFTMNO13_10720(nudB)
SYMK6K13_11570(nudB) K6K13_16485 K6K13_18595
METYMRY16398_35750(nudB)
AHNNCTC12129_01976(ntpA)
ASUBNLZ15_13030(nudB)
YREHEC60_07955(nudB)
SGOEA8O29_009175(nudB)
KINAB182_15680(nudB)
PDZHHA33_18245(nudB)
IZHFEM41_20405(nudB)
PSHISAMEA2665130_1125(nudB)
PSGCG163CM_07980(nudB)
EBFD782_1770
EBCC2U52_26385
EBUCUC76_24605
PSTSE05_14590
YPEYPO2054(ntpA)
YPKy2256(ntpA)
YPHYPC_2261(nudB)
YPAYPA_1436
YPNYPN_1531
YPMYP_1897(nudB)
YPPYPDSF_1068
YPGYpAngola_A2425
YPZYPZ3_1770(ntpA)
YPTA1122_15890(nudB)
YPDYPD4_1814(ntpA)
YPXYPD8_1736(ntpA)
YPWCH59_4069(nudB)
YPJCH55_682(nudB)
YPVBZ15_1483(nudB)
YPLCH46_3057(nudB)
YPSYPTB2037(nudB)
YPOBZ17_428(nudB)
YPIYpsIP31758_2034
YPYYPK_2147
YPBYPTS_2096
YPQDJ40_271(nudB)
YPUBZ21_1316(nudB)
YPRBZ20_75(nudB)
YPCBZ23_1598(nudB)
YPFBZ19_1392
YENYE2396(nudB)
YEPYE105_C1893
YEYY11_11861
YELLC20_02441
YEWCH47_1749(nudB)
YETCH48_3523(nudB)
YEFFORC2_1866
YEEYE5303_16571(ntpA)
YSIBF17_19220(nudB)
YALAT01_591(nudB)
YFRAW19_1037(nudB)
YINCH53_3798(nudB)
YKRCH54_625
YROCH64_400(nudB)
YRUBD65_179(nudB)
YRBUGYR_00975(nudB)
YMADA391_12230
YHID5F51_09695
YCAF0T03_11790(nudB)
YMOHRD69_16605(nudB)
SMARSM39_2254(nudB)
SMACSMDB11_2049(nudB)
SMWSMWW4_v1c27940(nudB)
SPESpro_2780
SRRSerAS9_2873
SRLSOD_c26220(nudB)
SRYM621_14300(nudB)
SPLYQ5A_014530(nudB)
SRSSerAS12_2874
SRASerAS13_2875
SMAFD781_2524
SLQM495_13960(nudB)
SERFL085_14850
SERSSERRSCBI_13145
SFWWN53_22690(nudB)
SFGAV650_18510(nudB)
SRZAXX16_2602
SERASer39006_015270
SERQCWC46_15265
SERMCLM71_13100
SQUE4343_02170(nudB)
SFJSAMEA4384070_2823(nudB)
SOFNCTC11214_04085(nudB)
SSURATE40_010590
SURIJ0X03_09995(nudB)
SRHZFO014_20570(nudB)
SENPKHA73_13735(nudB)
SFOZ042_00755(nudB)
RAHRahaq_1714
RACEJHW33_02790(nudB)
RAQRahaq2_1794
RAAQ7S_08355(nudB)
ROXBV494_08275
RVCJ9880_16455(nudB)
GQUAWC35_00465(nudB)
EAMEGXP68_09605(nudB)
RBADH2866_17680(nudB)
ECAECA2495(nudB)
PATREV46_12020(nudB)
PATOGZ59_20610(nudB)
PCTPC1_1816 PC1_2899
PCCPCC21_018230
PCVBCS7_09095(nudB)
PWAPecwa_2100
PPARA8F97_08365
PECW5S_2045
PWSA7983_17745
PPOABJK05_04130
PBRAB5S52_12585
PPUJE2566_09740(nudB) E2566_13890
PARII2D83_09935(nudB)
PAQUDMB82_0011845(nudB)
PVZOA04_24450(nudB)
PPAVLOZ86_09350(nudB)
PQUIG609_008735(nudB)
DDDDda3937_01617(nudB)
DZEDd1591_2261
DDCDd586_2201
DZCW909_09100(nudB)
DSOA4U42_19000(nudB)
CEDLH89_02220(nudB)
DFNCVE23_10550
DDQDDI_1820
DAQDAQ1742_02310(nudB)
DICDpoa569_002035(nudB)
DDADd703_0969 Dd703_2159
BGJAWC36_08840(nudB)
BRBEH207_09760
BNGEH206_12590
BIZHC231_09610(nudB)
LBQCKQ53_14895
LPOPI6N93_08795(nudB)
SGLSG1258
SODSant_1683(nudB)
PESSOPEG_2611(nudB)
SLIGGTU79_16225(nudB)
EAMEAMY_2068(ntpA)
EAYEAM_2007(nudB)
ETAETA_14860
EPYEpC_15610
EPREPYR_01682(ntpA)
EBIEbC_25120
ERJEJP617_31380
EGEEM595_2137(nudB)
EPECI789_06520
ERWIGN242_11460(nudB)
ETPLU633_11395(nudB)
ERPLJN55_13385(nudB)
PAMPANA_2205(nudB)
PLFPANA5342_1959(ntpA)
PAJPAJ_1519(nudB)
PAQPAGR_g1891
PVAPvag_1670(ntpA)
PAGGAL522_15475
PAOPat9b_2313
KLNLH22_11160(nudB)
PANTPSNIH1_14780(nudB)
PANPPSNIH2_06375(nudB)
PAGCBEE12_18405
PSTWDSJ_15300
PALHB1H58_16025
PANSFCN45_11060(nudB)
PEYEE896_08135(nudB)
PDISD8B20_09840
PERLAC65_08730(nudB)
PGZC2E15_12250
PCDC2E16_12490
MINTC7M51_01643(nudB)
MTHIC7M52_01178(nudB)
TCIA7K98_10780
TPTYNCTC11468_02124(nudB)
PLUplu2108(nudB)
PLUMA4R40_10570(nudB)
PAYPAU_02473(nudB)
PTTVY86_20425(nudB)
PAKHB0X70_10945
PLUICE143_10860
PMRPMI1112(ntpA)
PMIBBB2000_1150(ntpA)
PVLAOB99_07580(nudB)
PVGCRN77_12210
PHAUPH4a_16215
PROTBTA34_08370
PCOLF1325_10055(nudB)
PCIBF9282_10085(nudB)
PPEEI6G31_00330(nudB)
XBOXBJ1_2263(nudB)
XBVXBW1_1940(nudB)
XNEXNC1_2147(nudB)
XNMXNC2_2076(nudB)
XDOXDD1_2062(nudB)
XPOXPG1_1814(nudB)
XHOA9255_04410
XBUHGO23_10715(nudB)
PSIS70_20240(nudB)
PSXDR96_2947(nudB)
PSTABGK56_02230
PRGRB151_020870(nudB)
PALACO695_15230
PHEINCTC12003_02180(nudB)
PRQCYG50_06410(nudB)
PRJNCTC6933_01795(nudB)
PVCG3341_11080(nudB)
PMAGJI723_10975(nudB)
MMKMU9_2014
ASYAUT07_00654(nudB)
ANSArsFIN_17520(nudB)
AEDE3U36_03335(nudB)
AETLDL57_08715(nudB)
MWIMNY66_07685(nudB)
EICNT01EI_1595
ETRETAE_1436(ntpA)
ETDETAF_1331
ETEETEE_3434
ETCETAC_06745
EDLAAZ33_07470(nudB)
EHOA9798_09820
HAVAT03_09760(nudB)
HPARAL518_16010
OPODSM2777_09805(nudB)
LPVHYN51_02230
PFQQQ39_10110(nudB)
PRAGEKN56_08990(nudB)
LRINCTC12151_02007(nudB)
HINHI_0316
HITNTHI0434(ntpA)
HIPCGSHiEE_01475(ntpA)
HIQCGSHiGG_04395
HIFHIBPF_02600
HILHICON_11600
HIUHIB_04340
HIER2846_0264(ntpA)
HIZR2866_0256(ntpA)
HIKHifGL_001755(nudB)
HIAH733_0212(nudB)
HIHNF38_03795
HIWNTHI477_01361(nudB)
HICNTHIC486_00672(nudB)
HIXNTHI723_01369(nudB)
HPRPARA_10860
HDUHD_0598(ntpA)
HAYC3V42_06160
HPITNCTC13334_01068(nudB)
HHZNCTC10839_00930(nudB)
HAEGNCTC8502_00907(nudB)
HPAAE5Q53_07730(nudB)
HSEML3077_03995(nudB)
HAPHAPS_0944(ntpA)
HPAZK756_02040
HPASJL26_01570
HPAKJT17_10455
GLECJD39_05000
HSOHS_0507(ntpA)
HSMHSM_1764
PMUPM0981(ntpA)
PMVPMCN06_0249(nudB)
PULNT08PM_0250
PMPPmu_01870(nudB)
PMULDR93_994(nudB)
PDAG4362423_00133(nudB)
PSKYA6B44_01860
PATLKGI96_01495(nudB)
PCAIK7G93_000203(nudB)
MSUMS0709(mutT)
BSUNA4G13_01350
MHTD648_5800
MHQD650_22320
MHATB824_20970
MHXMHH_c11300(nudB)
MHAEF382_10770(nudB)
MHAMJ450_09690(nudB)
MHAOJ451_11000(nudB)
MHALN220_02880(nudB)
MHAQWC39_10965
MHAYVK67_10970
MVRX781_5520
MVIX808_4770
MVGX874_4860
MVEX875_15970
MANNGM695_04565(nudB)
MGRAA4G16_00325
MBOSICJ55_04785(nudB)
MPEGHV560_05010(nudB)
APLAPL_1150(ntpA)
APJAPJL_1170(mutT2)
APAAPP7_1209(ntpA)
ASUAsuc_1804
ASIASU2_00975(nudB)
ASSASU1_00980(nudB)
AEUACEE_00825
APORDDU33_04840
AIOEXH44_01920(nudB)
ADPNCTC12871_00632(ntpA)
ALIGNCTC10568_01439(ntpA)
AAPNT05HA_1357
AAZADJ80_10670
AATD11S_1851
AAOANH9381_0027
AAND7S_00637
AAHCF65_02850
AACNAANUM_1275(ntpA)
AACTACT75_09445
ASEGNCTC10977_01882(nudB)
GANUMN179_00267
BTOWQG_13670
BTREF542_8370
BTRHF543_9660
BTRAF544_14060
APAGEIA51_07040
AVTNCTC3438_01045(nudB)
RPNENCTC8284_01297(nudB)
RHEYFEE42_04245(nudB)
RHAEIHV77_09090(nudB)
OOIA6A10_05625
FCLA4G17_05530
BHUDA6A11_06910
PAETNCTC13378_01269(nudB)
LAREHIV01_012525
RHDR2APBS1_1227
RTHLRK53_07670
DTXATSB10_15820
VCMVCM66_A0332
VVUVV2_0106
VVYVVA0615
VVMVVMO6_03603
VVLVV93_v1c36160
VPAVPA0758
VPBVPBB_A0698
VPKM636_03245
VPFM634_21730
VPHVPUCM_20657
VHAVIBHAR_05631
VCAM892_23470
VAGN646_4159
VEXVEA_000271
VDBAL552_06525 AL552_17010
VHRAL538_23750
VNAPN96_19925
VOWA9237_21890
VROBSZ04_00400
VSPVS_II1195
VEJVEJY3_19191
VCYIX92_27770
VCTJV59_24640
VBRA6E01_06170
VTAB0398
VAFD1115_18330
VNLD3H41_18980
VCCFAZ90_16495
VASGT360_21410
VSRVspart_00461
VKABTD91_13340
VGIMID13_21660
VSLLTQ54_01040 LTQ54_23025
VFIVF_1352
VFMVFMJ11_1429
VSAVSAL_I1472
AWDAWOD_I_1299
PGBH744_1c0788 H744_1c1167
PGHFH974_16300 FH974_20445
SALYE8E00_08195
SKSFCN78_05970
AJORZ95_14705
ACHICDG60_03260
ABOUACBO_27170
PATPatl_2947
PSEOOM33_18790
PRRAT705_20845
PLZS4054249_21345
PPISB1L02_23580
PSPOPSPO_b0829(nudB)
PTUPTUN_a2274(nudB)
PSENPNC201_22440(nudB)
PXIJ5O05_19505(nudB)
PVBJ5X90_21010(nudB)
PSAZPA25_34780(ntpA)
AMCMADE_000001021165
AMHI633_06875
AMAAamad1_06900
AMALI607_06180
AMAEI876_06470
AMAOI634_06590
AMADI636_06980
AMAII635_06880
AMAGI533_06540
AMACMASE_06055
AMBAMBAS45_06265
AMGAMEC673_06110
AMKAMBLS11_06110
ALTambt_12130
AALEP13_06730
AAUSEP12_06560
ASPAOR13_2227
ASQAVL57_09825
AAWAVL56_08970
ALRDS731_07945(nudB)
ALEAV939_08840
ALZAV940_08620
APELCA267_003020(nudB)
SALMD0Y50_05855
SALKFBQ74_11570(nudB)
SMAAIT774_11330(nudB)
GAGGlaag_1379
GNIGNIT_1232(ntpA)
GPSC427_4063(ntpA)
PMESFX988_03968
LALAT746_12180
SALHHMF8227_01858(nudB)
PAEWKIH87_11425(nudB)
AGZM0C34_10470
PINPing_2065
CELLCBR65_15225
LSSNCTC12082_00243
TIGTHII_0936
BLEPAL038_11335(nudB)
ALVAlvin_0721
ATEPAtep_04390(ntpA)
TVIThivi_1026
TMBThimo_3046
MPURMARPU_13435
TSYTHSYN_05320
TTPE6P07_04925(nudB)
THIPN838_18370(nudB)
CJAPGWK36_05165(nudB)
THIMKFB96_12810(nudB)
TBOGLT988_08630(nudB)
HHCM911_02960
EBSECTOBSL9_0355
TGRTgr7_2239
APRSBI364_14275
WOCBA177_14000
GAIIMCC3135_27615(nudB)
TTCFOKN1_1087
THICTspCOW1_15740(ntpA)
BSANCHH28_06700
RFOREIFOR_00684(nudB)
AHAAHA_2471
AHYAHML_10610
AHRV428_10900
AHPV429_10910
AHJV469_12495
AHHRY45_10525
AHIVU14_12400
AAJBOQ57_09910
ASAASA_2328
AEOO23A_p1612
AVRB565_1688
AVOAMS64_08325
ADHCK627_16230
AEMCK911_07530
ARVC7N77_13180
AELNCTC12917_02312
AALLI6G90_00760
OCEGU3_12515
OCMCBP12_00895
OPFCBP31_02910
ZDFAN401_06085
GAPGAPWK_2391
FPPFPB0191_01319
ORBIPMB12_05975(nudB)
SLIMSCL_2260
SVASVA_3323
ACIIC4901_13835
ATYA9R16_003095(nudB)
SEDSAAY24_16115
REVHUE57_15185(nudB)
EPSL0Y14_09715(nudB)
ENMEBS_1670(ntpA)
NMENMB0642(ntpA)
NMPNMBB_0717
NMHNMBH4476_1548
NMDNMBG2136_0580
NMMNMBM01240149_1455
NMSNMBM01240355_0643
NMQNMBM04240196_1525(nudB)
NMZNMBNZ0533_0684(nudB)
NMANMA0852
NMWNMAA_0490(ntpA)
NMXNMA510612_0953(ntpA)
NMCNMC0585(ntpA)
NMNNMCC_0590(ntpA)
NMTNMV_1767(ntpA)
NMINMO_0528(ntpA)
NGONGO_0224
NGKNGK_0359
NLANLA_15900(ntpA)
NELNELON_06410
NWESAMEA3174300_0582(ntpA)
NSIA6J88_13050
NMJNM96_07435
NEIBG910_00460
NEKCGZ77_11055
NFVFAH67_02860(nudB)
NSFFAH66_02950(nudB)
NZLD0T92_07195
NAQD0T90_07745
NBLGJV52_01115(nudB)
NZOSAMEA4504057_1119(ntpA)
NCINCTC10296_01999(ntpA)
NCZNCTC10294_00289(ntpA)
NANINCTC12227_00763(ntpA)
NBCH3L91_05115(nudB)
NWDH3L96_07660(nudB)
NSGH3L94_00140(nudB)
NMUSH7A79_1172
NSCJ7445_06865(nudB)
NPFLPB400_05890(nudB)
NDNH3L92_04620(nudB)
NDULVJ88_05895(nudB)
NAWLVJ86_07310(nudB)
NMBMON40_09890(nudB)
SALVSALWKB2_0811
KKIKKKWG1_1780(nudB)
KOAH3L93_06465(nudB)
KPOTLVJ84_05310(nudB)
VFFVITFI_CDS3021
VITADP71_09190
VSTLVJ81_08425(nudB)
VMSLVJ82_02120(nudB)
ECORSAMEA4412678_1237(nudB)
EEXEZJ17_00750(nudB)
SMURBWP33_10510
AFFH3L97_04900(nudB)
ACRSLVJ80_06360(nudB)
CSTEH3L98_06270(nudB)
CKHLVJ77_00735(nudB)
PTESJQU52_08910(nudB)
MCERMON37_07690(nudB)
USULVJ78_05770(nudB)
UTELVJ83_07340(nudB)
WBOMIS45_07000(nudB)
CVICV_2960(ntpA)
CVCBKX93_05495
CHROCXB49_06725
CHRIDK842_21805
CHRBDK843_04545
CRZD1345_10205
CHRMFYK34_09025(nudB)
CHAECH06BL_20900(ntpA)
IODEJO50_08305
IFLC1H71_16105
LHKLHK_01832(ntpA-1)
PSENH8B_3062
JEUBJP62_01530
AQLBXU06_07445
AMAHDLM_0823
AQSDKK66_01225
DEEHQN60_12430(nudB)
CHIZHQ393_06000(nudB)
CFONHZU75_17220(nudB)
VOGLCH97_01645(nudB)
RSORSc0468(ntpA)
RSCRCFBP_21016(nudB)
RSLRPSI07_2900(nudB)
RSNRSPO_c02926(nudB)
RSMCMR15_30439(nudB)
RSEF504_494
RSYRSUY_28010(nudB)
RPIRpic_0343
RPFRpic12D_0358
RPJN234_02205
RMNTK49_05410
RINACS15_0464
RPUCDC45_02400
RSGJK151_00520(nudB)
REHH16_A0455(h16_A0455)
CNCCNE_1c04760(nudB)
CUHBJN34_02800
REUReut_A0441
RMERmet_0380(ntpA)
CTIRALTA_A0398(nudB)
CBWRR42_m0508
CGDCR3_0370(ntpA)
CCUPBKK81_04640
CUPBKK80_03985
CUUBKK79_08280
CPAUEHF44_03490
COXE0W60_12860(nudB)
CCAMM5D45_02070(nudB)
BMABMA0194(ntpA)
BMVBMASAVP1_A2751(ntpA)
BMLBMA10229_A2327(ntpA)
BMNBMA10247_2407(ntpA)
BMALDM55_1597
BMAEDM78_396
BMAQDM76_1576
BMAIDM57_2230
BMAFDM51_3168
BMAZBM44_884
BMABBM45_519
BPSBPSL0645
BPMBURPS1710b_0853(ntpA)
BPLBURPS1106A_0692(ntpA)
BPDBURPS668_0677(ntpA)
BPRGBP346_A0604(nudB)
BPSEBDL_1359
BPSMBBQ_2782
BPSUBBN_2905
BPSDBBX_3306
BPZBP1026B_I2880(ntpA)
BPQBPC006_I0679
BPKBBK_840
BPSHDR55_448
BPSABBU_1506
BPSOX996_55
BUTX994_2070
BTEBTH_I0561
BTQBTQ_583
BTJBTJ_1902
BTZBTL_3138
BTDBTI_3143
BTVBTHA_3421
BTHEBTN_1574
BTHMBTRA_16
BTHADR62_1761
BTHLBG87_3331
BOKDM82_73
BOCBG90_948
BUUWS70_14515
BSAVWS86_15770
BHGI6G56_04415(nudB)
BVIBcep1808_2830
BVEAK36_1172
BURBcep18194_A6051
BCMBcenmc03_2751
BCHBcen2424_2724
BCJBCAL0881
BCENDM39_2815
BCEWDM40_341
BCEOI35_2787(ntpA)
BAMBamb_2775
BACBamMC406_2642
BMJBMULJ_02686(ntpA)
BMUBmul_0575
BMKDM80_2191
BMULNP80_2858
BCTGEM_0717
BCEDDM42_2348
BCEPAPZ15_01480
BDLAK34_365
BPYRABD05_03640
BCONNL30_26705
BUBBW23_2170
BDFWI26_13135
BLATWK25_13200
BTEIWS51_23995
BSEMWJ12_13630
BPSLWS57_32370
BMECWJ16_13975
BSTGWT74_14435
BSTLBBJ41_15155
BANNJFN94_13970(nudB)
BGLbglu_1g30750
BGUKS03_529
BUGBC1001_0372
BGFBC1003_0383
BGDbgla_1g34320
BGOBM43_926
BYIBYI23_A003040
BUKMYA_2481
BUEBRPE67_ACDS02940
BULBW21_3292
BUQAC233_02090
BGPBGL_1c32380
BPLAbpln_1g31390 bpln_2g14510
BUDAQ610_15745
BUMAXG89_07920
BUIAX768_01020
BURKDM992_06330
BXEBxe_A4042
BXBDR64_1719
BPHBphy_0382
BGEBC1002_0377
BPXBUPH_04263
BPYBphyt_0657
BUZAYM40_02010
BFNOI25_1054
BCAIK788_0008389
PSPWBJG93_10765(nudB)
PARABTO02_03015
PARBCJU94_02975
PHSC2L64_02145
PTERC2L65_01915
PGPCUJ91_02240
PCJCUJ87_01940
PTSCUJ90_02140
PCAFDSC91_005824
PMEGFNZ07_30540(nudB)
PTROG5S35_12280(nudB)
PGISI6I06_09470(nudB)
PACPFAZ97_12030(nudB)
PACSFAZ98_11680(nudB)
PEWKZJ38_20785(nudB)
PDIOPDMSB3_0495(nudB)
BRHRBRH_02094
PNUPnuc_1891
PNEPnec_1596
PDQCL55_00018760
POHDPM16_07250
PTRPDCO17_09410
PANIDCO16_10180
PPALAOC06_07830(nudB)
PCOSC2747_09460(nudB)
PPKU875_19685
PPNODA70_12370
PPNMLV28_18330
PRBX636_14500
PPULRO07_12625
PSPUNA29_08695
PAPISG18_12950
PVEUC34_04385
POXMB84_08825
PTXABW99_13830
PFGAB870_15380
PNRAT302_12700
PANDDRB87_03950
PFIBPI93_003990(nudB)
PCOMNTU39_04730(nudB)
HYFDTO96_102040(nudB)
LMIRNCTC12852_00802(nudB)
MCYSMCB1EB_0361
CABASBC2_03830(nudB)
BUOBRPE64_ACDS03030
LIMNHKT17_02145(nudB)
CARIFNU76_00220(nudB)
VTRMYVALT_G_01280(nudB)
VLAGKR41_00697(nudB)
RFRRfer_1298
RACRA876_14025
RHYRD110_08265
RHFEUB48_04725(nudB)
RHGEXZ61_05905(nudB)
RHOAHZ993_21280(nudB)
POLBpro_0867
PNAPnap_0910
POSDT070_10680
POOF7R28_19930(nudB)
AAVAave_3635
AJSAjs_0876
AAAAcav_3552
ACKC380_04765
ACRABSY15_653
ACIDCBP33_14840
ACIPCBP36_15245
ACINCBP34_15640
ACISCBP35_03685
ACIOEAG14_15685
AMONH9L24_20185(nudB)
AANTHUK68_15510(nudB)
ARADKI609_18115(nudB)
DACDaci_5451
DELDelCs14_1159
DTSBI380_27865
DHKBO996_25375
DLAI6G47_28480(nudB)
VAPVapar_4121
VPEVarpa_4789
VPDVAPA_1c42760
VAAAX767_05065
VBOCKY39_07190
VAMC4F17_25000
CTTCtCNB1_0801
CTESO987_04315
CKEB5M06_03025
COFFOZ74_13200(nudB)
CAQTKAQ61_00915(nudB)
CODOLAD35_16950(nudB)
ADNAlide_0961
ADKAlide2_0924
RTARta_31130(nudB)
RTEAHK414_05790(nudB)
OTKC6570_16695
OTDJ1M35_16875(nudB)
LIML103DPR2_00808(nudB)
LIHL63ED372_02517(nudB)
HYRBSY239_597
HYBQ5W_02620
HYLLPB072_05130
HYCE5678_11885(nudB)
HPSEHPF_19375(nudB)
HYNF9K07_24990(nudB)
HTNKI616_06775(nudB)
DPYBA022_10705
DIHG7047_16905(nudB)
DAERH9K75_18305(nudB)
DRGH9K76_04975(nudB)
DIADtpsy_0805
SIMPC6571_03800
MELMC7H73_13640
MELAC6568_13065
MJELVC68_04235(nudB)
KIAG8A07_20565(nudB)
STHMIS481_05150(nudB)
PBHAAW51_1251
MPTMpe_A1071
METPC1M51_03080
RGERGE_10970(ntpA)
RBNRBXJA2T_07105
RDPRD2015_3821
MIUABE85_16100
SNNEWH46_14995(nudB)
IDCLRM40_05880(nudB)
ATERMW290_28445(nudB)
HARHEAR2843
MMSmma_3098(ntpA)
JAGGJA_4844
JABVN23_08270
JAZYQ44_24420
JALBZG29_03745
JSVCNX70_03790
JAJEKL02_03960(nudB)
JASFJQ89_20775(nudB)
JLVG3257_03745(nudB)
HSEHsero_0236(ntpA)
HSZACP92_01165
HHTF506_20600
HRBHrubri_0220(ntpA)
HEEhmeg3_22390
HHFE2K99_01290(nudB)
HFRG5S34_01020(nudB)
CFUCFU_0654(ntpA)
CARELT85_0711
CPRACPter91_0765
MNRACZ75_16150
MASWAM586_03675
MASSCR152_05060
MTIMDIR46_11360
MASYDPH57_23410
MANCIV454_11155(nudB)
MFYHH212_05775(nudB)
MASZC9I28_25760
MALIEYF70_26165(nudB)
MUMFCL38_23195(nudB)
MFLAGO485_18755(nudB)
MPLIE1742_19065(nudB)
DUGHH213_13785(nudB)
OFOBRW83_0124(nudB)
UPVEJN92_12660
UPIEJG51_015165(nudB)
NOKFAY22_14335(nudB)
GLCJQN73_11210(nudB)
LCHLcho_4015
TINTint_2827
THITHI_3376
PKTAT984_13480
RGUA4W93_20840
AONDEH84_12505
XYKGT347_07410(nudB)
TTWLCC91_07250(nudB)
NEUNE2253(ntpA)
NETNeut_0615
NITNAL212_2038
NIINit79A3_1606
NCOAAW31_02375
NURATY38_14785
NSTNstercoris_01839
NMUNmul_A0604
NLCEBAPG3_005160
SHDSUTH_00340(ntpA)
METRBSY238_1456
DOEDENOEST_0308(nudB)
TBDTbd_0444
MFAMfla_2382
MMBMmol_2280
MEHM301_2626
MEIMsip34_2449
MEPMPQ_2392
MBACBN1209_1628(nudB)
MBATBN1208_1327(nudB)
MEUACJ67_00655
MPAUZMTM_22660(ntpA)
SLTSlit_0976
GCAGalf_2461
FAMOYT1_ch1005
NIMW01_26270(ntpA)
NARCNTG6680_1065(nudB)
FKUFGKAn22_05480(ntpA)
SEMEMIZ01_0917
SDRSCD_n00664(ntpA)
SULFCAP31_10260
SPLBSFPGR_07530(ntpA)
SNIVSFSGTM_19750(ntpA)
SLACSKTS_05770(ntpA)
URUDSM104443_03602(nudB)
UPLDSM104440_03137(nudB)
DSUDsui_1312
ARESIWH25_07235(nudB)
AIQAzoinq_04640(nudB)
RBUPG1C_00835
OTROTERR_05350(ntpA)
NIVJY500_05850(nudB)
EBAebA4334(mutT)
ABREpbN1_28370
APETToN1_15580
ATWC0099_04390
DARDaro_0631
DEYHYN24_02725
DDENKI615_18050(nudB)
QAUKI612_03560(nudB)
FLEKI610_16590(nudB)
AZAAZKH_3581(ntpA)
AZIAzCIB_3648
AZDCDA09_17720
AZQG3580_13285(nudB)
FPHOSHINM1_001610(ntpA)
FMYHO273_09155(nudB)
APPCAP2UW1_4161
DDZDSYM_05020
BPRCD521_1886
BEBAEM42_03085
BEBABWI17_09020
DBADbac_1399
DOAAXF15_12230
EAAI862_02025
MESPC1M53_27485
SAMESAMCFNEI73_Ch1730
EAHFA04_03255
ATUAtu6117
ARAArad_15010 Arad_8648(ialA)
ATFAch5_50330
ARUIG6M88_04045 G6M88_24905
AVQHRR99_10935
REIIE4771_CH03004 IE4771_PE00023
RLTRleg2_4630
RHNAMJ98_PB00024
RPHAAMC79_PA00024
REZAMJ99_PA00024
RADCO657_28485
RBANJ2J98_19960
OAHDR92_4579
PSFPSE_2021 PSE_2022
SILSPO0803
GALA0U94_03420
RRURru_A0455
RRFF11_02335
HAXBALOs_0338(ntpA)
BSTOC0V70_01865
ACUAtc_2791
ACZAcaty_c2642
ATXGCD22_03750(nudB)
BANBA_2713
BARGBAA_2713
BATBAS2528
BAHBAMEG_1881
BAIBAA_2778
BAXH9401_2585
BANTA16_27490
BANRA16R_27860
BANSBAPAT_2607
BANHHYU01_13470
BANVDJ46_1493
BCEBC2722
BCABCE_2741
BCZBCE33L2453(ntpA)
BCRBCAH187_A2776
BCBBCB4264_A2731
BCUBCAH820_2727
BCGBCG9842_B2570
BCQBCQ_2569
BCXBCA_2802
BALBACI_c26840(ntpA)
BNCBCN_2585
BCFbcf_13295
BCERBCK_21270
BTKBT9727_2488(ntpA)
BTLBALH_2441
BTBBMB171_C2437
BTCCT43_CH2698
BTFYBT020_13595
BTMMC28_1920
BTGBTB_c28270
BTIBTG_06115
BTNBTF1_11090
BTHTH175_ch2747
BTHUYBT1518_14985
BTWBF38_3889
BWEBcerKBAB4_0885 BcerKBAB4_3131
BWWbwei_1521 bwei_4020
BMYOBG05_2587 BG05_4902
BTYBtoyo_0012
BMYCDJ92_5605
BWDCT694_14500
BMOBMLA2C4_14395
BNTGSN03_05305
BIFN288_11145
BDAFSZ17_04685
BCIRC2I06_07250
BLEBleG1_0736
BKOCKF48_08960
LSPBsph_2614(ntpA)
LYSLBYS11_11520
LPAKGDS87_07985
FPNABE65_010730
FARABE41_006805
BVQFHE72_05310
RMFD5E69_03800
LMFLMOf2365_2679
LMCLm4b_02673
LMOGBN389_26680
LMPMUO_13515
LMOLLMOL312_2665
LMOJLM220_08545
LMOZLM1816_02557
LMOXAX24_11575
LMOOLMOSLCC2378_2708
LMOALMOATCC19117_2709
LMOKCQ02_13780
LMVY193_02090
LWElwe2650
LIVLIV_2646
LIIJL52_13940
LIWAX25_14160
LIAJL58_14180
LIOJL53_14630
LMARLAX80_013210
PXLBS614_11820
PCELHUB94_18090
BTSBtus_1046
KYRCVV65_10895
VIJJNUCC6_03145
LLAL168057(ylgG)
LLKLLKF_1182(folQ)
LLTCVCAS_1128(folQ)
LLSlilo_1058(ylgG)
LLDP620_06265
LLXNCDO2118_1156(folQ)
LLJLG36_1225(folQ)
LLMllmg_1335
LLCLACR_1277
LLRllh_6420
LLNLLNZ_06905
LLIuc509_1172
LLWkw2_1106
LGRLCGT_1025
LGVLCGL_1015
LPKLACPI_0975
LACTD7I46_03975
LACKFLP15_08990
LTIJW886_05660
SSASSA_0854
SGOSGO_1335(ntpA)
SIBSIR_0540
SANGSAIN_1132
SANSDK43_04450
SOII872_01805
LDBLdb0250
LBULBUL_0212
LDELDBND_0878
LHElhv_1205
LHVlhe_1098
LHHLBH_0975
LHDHUO_06140
LGLAO203_08785
LBHLbuc_1098
LBNLBUCD034_1231
LCUPL11_008995
LKFDNL43_09975
LHILG8J22_01462
LHIJP39_08390
LSALCA_1097
LBEMOO44_07585
CLJCLJU_c24630
CPASClopa_1067
CAHCAETHG_0527
STHSTH154
SPOAEQM13_17570
MCDMCRO_0092
STREGZL_02360
SDXC4B68_38420
SGDELQ87_09370
SPLACP981_29215
XYAET471_02555
STRREKD16_21930(nudB)
FRAFrancci3_2342
FREFranean1_4065
EGDGS424_017490
TROtrd_1564
STISthe_0798
TTRTter_0166
TANTKNN15_08435
PUVPUV_25150
WCHwcw_0563
SDYNMal52_59720
PCORKS4_11350(nudB)
HBSIPV69_21920
LBALebu_1242
LHFJCM16775_1309
LHGJMUB5056_1122
LTEJMUB4039_1351
LWDJCM16777_1085
GGRHKW67_02400
GBAJ421_3863
SRUSRU_1888
SRMSRM_02096
RMRRmar_0412
RMGRhom172_0411
RBARAWN76_017215
IALIALB_1763
MROMROS_2603
CPRVCYPRO_1160
LOKILokiarch_13460(rppH) Lokiarch_31290(mutX)
 » show all
Reference
1  [PMID:4362677]
  Authors
Suzuki Y, Brown GM
  Title
The biosynthesis of folic acid. XII. Purification and properties of dihydroneopterin triphosphate pyrophosphohydrolase.
  Journal
J Biol Chem 249:2405-10 (1974)
Reference
2  [PMID:8798731]
  Authors
O'Handley SF, Frick DN, Bullions LC, Mildvan AS, Bessman MJ
  Title
Escherichia coli orf17 codes for a nucleoside triphosphate pyrophosphohydrolase member of the MutT family of proteins. Cloning, purification, and characterization of the enzyme.
  Journal
J Biol Chem 271:24649-54 (1996)
DOI:10.1074/jbc.271.40.24649
  Sequence
[eco:b1865]
Reference
3  [PMID:15611104]
  Authors
Klaus SM, Wegkamp A, Sybesma W, Hugenholtz J, Gregory JF 3rd, Hanson AD
  Title
A nudix enzyme removes pyrophosphate from dihydroneopterin triphosphate in the folate synthesis pathway of bacteria and plants.
  Journal
J Biol Chem 280:5274-80 (2005)
DOI:10.1074/jbc.M413759200
  Sequence
[llm:llmg_1335]
Reference
4  [PMID:17698004]
  Authors
Gabelli SB, Bianchet MA, Xu W, Dunn CA, Niu ZD, Amzel LM, Bessman MJ
  Title
Structure and function of the E. coli dihydroneopterin triphosphate pyrophosphatase: a Nudix enzyme involved in folate biosynthesis.
  Journal
Structure 15:1014-22 (2007)
DOI:10.1016/j.str.2007.06.018
  Sequence
[eco:b1865]
Other DBs
ExplorEnz - The Enzyme Database: 3.6.1.67
IUBMB Enzyme Nomenclature: 3.6.1.67
ExPASy - ENZYME nomenclature database: 3.6.1.67
BRENDA, the Enzyme Database: 3.6.1.67

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