KEGG   ENZYME: 4.1.2.43
Entry
EC 4.1.2.43                 Enzyme                                 
Name
3-hexulose-6-phosphate synthase;
D-arabino-3-hexulose 6-phosphate formaldehyde-lyase;
3-hexulosephosphate synthase;
3-hexulose phosphate synthase;
HPS
Class
Lyases;
Carbon-carbon lyases;
Aldehyde-lyases
Sysname
D-arabino-hex-3-ulose-6-phosphate formaldehyde-lyase (D-ribulose-5-phosphate-forming)
Reaction(IUBMB)
D-arabino-hex-3-ulose 6-phosphate = D-ribulose 5-phosphate + formaldehyde [RN:R05338]
Reaction(KEGG)
R05338
Substrate
D-arabino-hex-3-ulose 6-phosphate [CPD:C06019]
Product
D-ribulose 5-phosphate [CPD:C00199];
formaldehyde [CPD:C00067]
Comment
Requires Mg2+ or Mn2+ for maximal activity [1]. The enzyme is specific for D-ribulose 5-phosphate as substrate as ribose 5-phosphate, xylulose 5-phosphate, allulose 6-phosphate and fructose 6-phosphate cannot act as substrate. In addition to formaldehyde, the enzyme can also use glycolaldehyde and methylglyoxal [7]. This enzyme, along with EC 5.3.1.27, 6-phospho-3-hexuloisomerase, plays a key role in the ribulose-monophosphate cycle of formaldehyde fixation, which is present in many microorganisms that are capable of utilizing C1-compounds [1]. The hyperthermophilic and anaerobic archaeon Pyrococcus horikoshii OT3 constitutively produces a bifunctional enzyme that sequentially catalyses the reactions of this enzyme and EC 5.3.1.27, 6-phospho-3-hexuloisomerase [6]. This enzyme is a member of the orotidine 5'-monophosphate decarboxylase (OMPDC) suprafamily [5].
History
EC 4.1.2.43 created 2008
Pathway
ec00030  Pentose phosphate pathway
ec00680  Methane metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K08093  3-hexulose-6-phosphate synthase
K13812  bifunctional enzyme Fae/Hps
K13831  3-hexulose-6-phosphate synthase / 6-phospho-3-hexuloisomerase
Genes
EUMECUMN_2963
STMSTM2755
SEOSTM14_3320
SEVSTMMW_27231
SEYSL1344_2739(hxlA)
SEMSTMDT12_C28070
SEJSTMUK_2743
SEBSTM474_2890
SEFUMN798_2989(hxlA)
SETUSTU288_13940
SETCCFSAN001921_03340
SENRSTMDT2_26611
SENDDT104_27571
SENICY43_14395
SEHSeHA_C2929(hxlA)
SHBSU5_03243
SENHCFSAN002069_18505
SEEHSEEH1578_22575
ECLZLI64_16165
ECANCWI88_05395(hxlA)
ECHGFY206_18835(hxlA)
KPNKPN_02957
KPYKPNIH31_18210
KMIVW41_11030
KOCAB185_13840
KLWDA718_10170(hxlA)
RTGNCTC13098_03929
CITZE4Z61_22610(hxlA)
PGELG71_08965
SODSant_0061
VSHBSZ05_17120
MCAMCA2738 MCA3043 MCA3049
METUGNH96_02035(hxlA) GNH96_02065(hxlA) GNH96_04130(hxlA)
MMTMetme_0742 Metme_4080
MDNJT25_012675 JT25_012930
MDHAYM39_02470 AYM39_02740
MKOMKLM6_0536 MKLM6_0590
METLU737_21900(hxlA)
MPADKEF85_01965(hxlA) KEF85_12785(hxlA)
MELLIVG45_20185(hxlA)
MAHMEALZ_1912(hpsi2) MEALZ_3953(hps1)
MBUREQU24_11340(hxlA)
MPSYCEK71_00435(hxlA) CEK71_18985
MMAIsS8_1135 sS8_1148
MMOBF6R98_00315(hxlA) F6R98_00325(hxlA)
MEINmethR_P2885
MOZMoryE10_01110 MoryE10_06560 MoryE10_07570
MISZMishRS11D_06510
MESLKKZ03_07025(hxlA)
MEJQ7A_2498(hxlA) Q7A_2501(hxlA)
MECQ7C_1679 Q7C_1682
MPINLGT42_003280(hxlA) LGT42_003295(hxlA)
ORBIPMB12_08420(hxlA)
BPDZBBN53_16310
ACIDCBP33_16730
CSERCCO03_04105
MFAMfla_0250 Mfla_1654
MMBMmol_0313 Mmol_1338
MEHM301_0304 M301_1547
MEIMsip34_0268
MEPMPQ_0281(sgbH) MPQ_1561
MBACBN1209_0202(rmpA) BN1209_0771(rmpA)
MBATBN1208_0845(hps)
MEUACJ67_02420 ACJ67_07420
MPAUZMTM_02460 ZMTM_11880
NSANitsa_1660
SLHYH65_04865
DAODesac_1176
XDIEZH22_21185
NOHG5V57_00560
ACUTMRB58_00780
SDOSD1155_05640(hxlA)
ADOA6F68_00105(proA_1)
GALA0U94_14275
GSPIGS75_14265
KBAA0U89_15345
BSUBSU03460(hxlA)
BSRI33_0397(hxlA)
BSLA7A1_1851
BSHBSU6051_03460(hxlA)
BSYI653_01730
BSUTBSUB_00396(hxlA)
BSULBSUA_00396(hxlA)
BSUSQ433_02070
BSOBSNT_06681(hxlA)
BSNBSn5_13315
BSQB657_03460(hxlA)
BSXC663_0338(hxlA)
BSPU712_01790
BSSBSUW23_01790(hxlA)
BSTGYO_0559(hxlA)
BLIBL02045(hxlA)
BLDBLi02805(hxlA)
BLHBaLi_c29000(hxlA)
BAYRBAM_003630(hxlA)
BAQBACAU_0303(hxlA)
BYABANAU_0305(hxlA)
BAMPB938_01575
BQYMUS_0325(hxlA)
BAMLBAM5036_0322(hxlA)
BAMARBAU_0337(hxlA)
BAMNBASU_0321(hxlA)
BAMBBAPNAU_0307(hxlA)
BAMTAJ82_01980
BAMYV529_03250(hxlA)
BMPNG74_00345(hxlA)
BAOBAMF_0310(hxlA)
BAZBAMTA208_01555(hxlA)
BQLLL3_00318(hxlA)
BXHBAXH7_00321(hxlA)
BAMIKSO_017855
BAMCU471_03230
BAMFU722_01860
BSIACWD84_20190(hxlA)
BAEBATR1942_20410
BVMB9C48_01845
BSONS101395_01722(hxlA)
BHTDIC78_08240(hxlA)
BMOJHC660_03860(hxlA)
BTEQG4P54_01945(hxlA)
BIQAN935_01795
BPUBPUM_2333
BPUMBW16_12650
BPUSUP12_11780
BIFN288_21395 N288_22430
BMETBMMGA3_06845(hps)
BSMBSM4216_0641
BGYBGLY_3090(hxlA)
BXIBK049_15320
BALTCFN77_12450(hxlA)
BSAFBSL056_12835
BITBIS30_12300
BFDNCTC4823_01217(hxlA_1) NCTC4823_03793(hxlA_2)
BSHILGQ02_03485(hxlA)
BCABEFK13_02150(hxlA)
BRYM0696_02000(hxlA)
BJSMY9_0361
GSTHW35_08370
BACWQR42_11740
BACPSB24_07990
BACBOY17_04480
BACYQF06_00690
BACLBS34A_04030(hxlA)
BALMBsLM_0362
BACSAUL54_09010
BACQDOE78_03635(hxlA)
BACAFAY30_22685 FAY30_23225(hxlA)
BHKB4U37_02010
BCIRC2I06_12975(hxlA) C2I06_17420
BMQBMQ_0891(hxlA) BMQ_1538(hxlA) BMQ_2942(hxlA)
BMDBMD_0891(hxlA) BMD_1519(hxlA) BMD_2971(hxlA)
BMHBMWSH_3691 BMWSH_4350(hxlA)
BMEGBG04_3186(hxlA) BG04_3830(hxlA) BG04_4896(hxlA) BG04_5472 BG04_5588(hxlA) BG04_5930(hxlA)
BEOBEH_06020 BEH_12940
BFXBC359_14510 BC359_19735
PKSIE339_01975(hxlA)
BAGBcoa_0968
BCLABC3351(hxlA)
BKWBkAM31D_07120(hxlA_1) BkAM31D_16315(hxlA_2)
BGIBGM20_16795
BONA361_15685 A361_15780 A361_26060
CGOTJ1899_06860 J1899_20250 J1899_21665(hxlA)
CFIRNAF01_02050 NAF01_14215(hxlA)
OIHOB2697 OB2806
OCNCUC15_15170(hxlA)
GTKGT3570_09830
GLIGLN3_03390
GTNGTNG_1490
GMCGY4MC1_3093
GGHGHH_c21400(hxlA)
GJFM493_16830
GEAGARCT_00704(hxlA_1) GARCT_02004(hxlA_2)
GELIB49_02240
GSRGS3922_12380
GEJA0V43_08225
GZAIC807_06470(hxlA)
GTHGeoth_3109
PTLAOT13_07080
PTBDER53_08130(hxlA)
ANMGFC28_662
ANLGFC29_964
ANDGRQ40_09545
ACAIISX45_01330(hxlA) ISX45_06735
LAGRFJQ98_01550
HMNHM131_14425
HLIHLI_12660
VIGBKP57_09220
VNECFK40_05180
VPTKBP50_20725
FARABE41_010275
SJEAAV35_011130
APAKAP3564_06145
PBUTDTO10_07700
PPSRI6J18_02975(hxlA) I6J18_08150(hxlA)
PFRIL8956_21565
GRCGI584_10025(hxlA)
NMKCHR53_10820(hxlA)
NTMBTDUT50_14180(hxlA)
NDTL1999_02995 L1999_22990(hxlA)
MEKUHUW50_04030(hxlA) HUW50_16935
MSEMGMB29_08440
MDGK8L98_13980(hxlA) K8L98_15450
MLITKDJ21_025570(hxlA) KDJ21_026155(hxlA)
AIAAWH56_012125
BLENNCTC4824_00834(hxlA_1) NCTC4824_02164(hxlA_2)
SEDDERJ70_14580 ERJ70_18455(hxlA)
BVQFHE72_04710 FHE72_17335(hxlA)
RMFD5E69_06120(hxlA)
BBEVBBEV_0241(hxlA)
STEAC0679_04045
SAUSA0528
SAVSAV0570
SAWSAHV_0568
SAHSaurJH1_0607 SaurJH1_2812
SAJSaurJH9_0593 SaurJH9_2736
SAMMW0525
SASSAS0528
SARSAR0574
SACSACOL0617
SAXUSA300HOU_0564
SAASAUSA300_0555
SAOSAOUHSC_00553
SAENWMN_0533
SADSAAV_0533(hxlA)
SUUM013TW_0558(hxlA)
SUVSAVC_02440
SUESAOV_0605
SUJSAA6159_00524(hxlA)
SUKSAA6008_00578(hxlA)
SUCECTR2_524(hxlA)
SUTSAT0131_00631
SUQHMPREF0772_12618(hxlA)
SUZMS7_0560(hxlA)
SUDST398NM01_0645
SUXSAEMRSA15_04970
SUWSATW20_06400
SUGSAPIG0645(hxlA)
SUFSARLGA251_05060
SAUASAAG_00991
SAUERSAU_000524(hps)
SAUNSAKOR_00559
SAUSSA40_0511
SAUUSA957_0526
SAUGSA268_0524
SAUZSAZ172_0572
SAUTSAI1T1_2004400
SAUJSAI2T2_1004420
SAUKSAI3T3_1004410
SAUQSAI4T8_1004400
SAUVSAI7S6_1004410
SAUWSAI5S5_1004370
SAUXSAI6T6_1004380
SAUYSAI8T7_1004410
SAUFX998_0612(hxlA)
SABSAB0520
SUYSA2981_0547
SAUBC248_0645
SAUMBN843_5640
SAUCCA347_586(hxlA)
SAURSABB_00621
SAUIAZ30_02885
SAUDCH52_02905
SAMSNI36_02840
SUHSAMSHR1132_05140
SERSERP0216
SEPSE_0341
SEPPSEB_00262
SEPSDP17_1647(hxlA)
SHASH2420
SHHShL2_02215(hxlA)
SSPSSP1619 SSP1626 SSP2148
SCASCA_0226 SCA_0711
SLGSLGD_02315
SLNSLUG_22330
SSDSPSINT_0249
SDTSPSE_2213(hxlA)
SDPNCTC12225_02420(hxlA)
SWAA284_00525 A284_10445 A284_12317
SPASSTP1_1658
SXYBE24_00590
SXLSXYLSMQ121_2137
SXOSXYL_02291
SHUSHYC_10795(hxlA)
SCAPAYP1020_2319
SSCHLH95_10395
SSCZRN70_11130
SAGQEP23_11365(hxlA)
SEQOSE1039_03970
SSIFAL483_08720(hxlA)
SCVA4G25_06550
SPETCEP67_09865(hxlA)
SCOHBZ166_02680
SNLBJD96_12035
SKLC7J89_12605(hxlA)
SFQC7J90_01805(hxlA)
SHOMEGX58_03330(hxlA)
SMUSC7J88_08345(hxlA)
SCARDWB96_11675(hxlA) DWB96_13070(hxlA)
SCHRDWB92_10940(hxlA)
SARLSAP2_21950
SPICSAMEA4384060_1853 SAMEA4384060_2297
SSHNCTC13712_00522
SSIMSAMEA4384339_0522
SDBCNQ82_05285(hxlA) CNQ82_12845(hxlA)
SLLOISP08_10875(hxlA)
SAULI6G39_01920(hxlA)
SSACI6I31_05635(hxlA)
SRAILN051_10085(hxlA)
SPSDJMB28_11605(hxlA)
STASHYI43_10895(hxlA)
SSCUCEP64_01020(hxlA)
SFFFOB90_09055(hxlA)
MLENH3V22_07285(hxlA)
MVTI6J10_09650(hxlA)
MCLMCCL_0037
MCAKMCCS_00640
MACRBHM04_10305
MBRUMGG13_01510(hxlA)
MEPIKFV12_00630(hxlA)
SHVAAT16_06530 AAT16_11280
ESIExig_2372
EANEab7_2216
EXMU719_13055
EXUESP131_15165
EACEKKI46_12995(hxlA)
PJDPjdr2_1185
GYMGYMC10_3885
PPYPPE_04673
PPMPPSC2_24305(hxlA)
PPOPPM_4826(hxlA)
PPOLX809_40845
PPQPPSQR21_049250(sgbH)
PPOYRE92_12975
PMSKNP414_07885(hxlA)
PMQPM3016_7402
PMWB2K_37330
PTAHPL003_05880
PSABPSAB_01345 PSAB_23295
PDUPDUR_01610 PDUR_26635
PBDPBOR_34755
PGMPGRAT_31065
PODPODO_29415
PAENP40081_36070
PAEFR50345_29525
PAEQR50912_32680
PSTEPSTEL_02005 PSTEL_26045
PAEAR70723_31470
PAEER70331_30230
PAEHH70357_33735
PAEJH70737_29170
PBJVN24_01055 VN24_04705
PRIPRIO_3567 PRIO_6499(hxlA)
PSONJI735_07210(hxlA)
PPEOABE82_24515
PNPIJ22_01440 IJ22_02540 IJ22_02590 IJ22_07980
POWIJ21_08240
PBVAR543_06015 AR543_17150
PXLBS614_16300
PYGAWM70_20320
PSWUSY83_08105
PDHB9T62_30300(hxlA)
PIBBBD41_28040
PCXLPB68_19235
PKBB4V02_00905
PAIHASL14_13410
PVOPVOR_20959
PLWD5F53_10835(hxlA)
PALBEJC50_17680 EJC50_19855(hxlA)
PCHIPC41400_00765(hxlA)
PPRTET464_10965(hxlA)
PBACHUB98_29030(hxlA)
PRZGZH47_09140(hxlA) GZH47_10845
PLYCGXP70_05785 GXP70_07130(hxlA)
PSOPKP014_02000(hxlA) KP014_04755
PTRIKDC22_31575(hxlA)
PALOE6C60_2213
PCELHUB94_23390(hxlA)
PTJJRJ22_27900(hxlA)
COHNKCTCHS21_15480
CCHLFPL14_29080(hxlA)
CHEBHH215_35310(hxlA)
SACAFFV09_02170(hxlA)
AFXJZ786_23545
AACOK1I37_20295(hxlA)
ACURJZ785_20925
EFFskT53_30650(hxlA)
PRTAUC31_15190
PANABBH88_04830 BBH88_17520
PMARB0X71_02090
PLXCW734_09535(hxlA) CW734_13380(hxlA)
PMATBBI11_12880
PDECH1Q58_12160(hxlA)
JEOJMA_08740 JMA_29170
SPSYAZE41_09415
PANCE2636_12245
PLAYDNR44_005605
TVUAB849_007475
LKLDKL58_01400 DKL58_07350
LCZLCAZH_0412
LCSLCBD_0422 LCBD_0453
LCELC2W_0417 LC2W_0448
LCWBN194_04270 BN194_04560
LCLLOCK919_0475
LPQAF91_01140
LPILBPG_03035
LPAPLBPC_0348
LCBLCABL_04190 LCABL_04490(hps)
LCXLCA12A_2395
LCHIKG086_13075
LZEKG087_13955
LMULBLM1_00435
LSNLSA_03490
LLEAYR59_00780
FIXM8332_02210(hxlA)
LBNLBUCD034_0077(hxlA)
LCUPL11_004190
LKFDNL43_05240
LHILG8J22_00758
LLAOLHL71_06165
LBRLVIS_0442
LBKLVISKB_0449
LCYLC20004_14635
LPDAYR62_06120
PCEPECL_1750
PACIA4V11_00360
LROSLROSL1_0262
LALWBTM29_04245
LALILA20249_07465
LHBD1010_15415
OOEOEOE_0131
OENDSM07_06150
LMMMI1_09731
LGCA9176_08390
WCBAO080_07995 AO080_11070
WJOFOL01_0737
WCFC6P13_08480
WSOWSWS_00759(hxlA)
WHEEFA59_09465
WEIEQG49_01015
LBEMOO44_01770(hxlA)
EGVEGCR1_00760(hxlA) EGCR1_06790
EAVEH197_05785(hxlA) EH197_09440(hxlA) EH197_17130
ESGEsVE80_07410
ERAFJ9537_02595(hxlA) J9537_09055
TOOC7K38_07925(hxlA)
VCPH9L18_04415
VHYG7082_07465
AURHMPREF9243_0240(hxlA)
CARNFPV25_08815(hxlA)
CACCA_C0396
CAESMB_G0404(sgbH)
CAYCEA_G0406
CBECbei_4647
CBZCbs_4647
CBEILF65_06885
CSRCspa_c49610
CDYF3K33_23655
CRWCROST_007110(hxlA)
CFBCLFE_041540(hxlA)
CAUNCLAUR_022850(hxlA)
CGELpsyc5s11_51560
ACOLK5I23_04770
ROBCK5_18950
ARFAR1Y2_1706 AR1Y2_3086 AR1Y2_3232
ACACEYQ97_01665(hxlA) EYQ97_02425(hxlA) EYQ97_09120(hxlA)
SINTK5I26_01765
CMIUB1H56_12255
HALSD7D81_05785
IFNGM661_03240
PFTJBW_00828
EUCEC1_08720
FROAALO17_19710
AARGAargi30884_01890 Aargi30884_03610 Aargi30884_04650(hxlA)
ABSIA9CBEGH2_06030(hxlA)
CIUG4D55_04125(hxlA) G4D55_16760(hxlA) G4D55_20095
LCGL3BBH23_22940(hxlA)
ERBA4V01_02795 A4V01_05815 A4V01_19475
MDXBTO20_03345 BTO20_30245
MAUBMAUB_30940 MAUB_31120
MMATMMAGJ_12220 MMAGJ_74070(hxlA)
CDXCDES_00570(rmpA)
CCYCSCMU_00950 SCMU_40760(hxlA)
RHARHA1_ro11329
ROAPd630_LPD04589
RKOJWS14_16845 JWS14_41255
ROZCBI38_29950
SRCM271_24320
SXNIAG42_32240
PSICJ4E96_11815
CMICMM_1123(sgaH)
CMSCMS1443(hps)
CMCCMN_01092(sgaH)
CMHVO01_04530
CCAPAES38_05195
CZHH9X71_05270(hxlA)
CPHAFGI33_07660(hxlA)
MIMAKG07_11695
MIHBJP65_05205
MICRBMW26_14455 BMW26_16485
MCHNHCR76_15235
RIAC7V51_11565
RFSC1I64_17210
RTEGSU10_14405
CUMNI26_12475
CUBBJK06_08985
CUGC1N91_12860
CQFGBG65_05940
AGYATC03_10775
AGMDCE93_00160
CARTPA27867_0095
MYLC3E77_13395
MSPOKXZ72_11835
SALCC2138_08145
SALAESZ53_12315
PLAPEAO79_07240(hxlA)
FRNF1C15_08050
AGXAGREI_3079(hxlA)
ARTArth_3708
ARRARUE_c04640(rmpA)
AREAL755_02190 AL755_14010
ARHAHiyo8_33930
ARZAUT26_19920
ARUASPU41_06005
ARQBWQ92_06605 BWQ92_09770 BWQ92_12695
ARNCGK93_01940(hxlA)
ARXARZXY2_3983(hxlA)
ARTHC3B78_00800(hxlA)
ASUNKG104_15075(hxlA)
AAUAAur_0494(hps)
PUEFV140_21525(hxlA)
PNVJMY29_02270(hxlA)
APNAsphe3_02200
PSULAU252_12865
PSEYGU243_15480(hxlA)
AAIAARI_06580(rmpA)
GARAOZ07_14970
GLUF0M17_03415(hxlA)
GMYXH9_05400(hxlA)
KPLKPaMU14_03840
SATKSA2016_1326 SA2016_3449 SA2016_3840 SA2016_3841
BRXBH708_07835
BRRC1N80_12905
BKIM4486_00580
PAUSNCTC13651_01296(hxlA)
NOWGBF35_26640
AMQAMETH_4519(hps) AMETH_4538(hps)
PSEEFRP1_13235 FRP1_13275
PSEQAD006_20915 AD006_20955
PECQAD017_00495 AD017_00535
MCRAID554_09635 ID554_24760
PFLAPflav_052080
VERHUT12_22585
BDEBDP_0013
BDNBBDE_0013
BANGBBAG_0932
BGXESN35_00230
BLEMBL8807_07050
BEUBE0216_04560
AEYCDG81_05575
ABAMB1s21122_01895
NHIB1s21160_01650
OLOADJ70_05660
ABAOBEQ56_09840
TTRTter_2273
ROOG5S37_04785
RBARB5319
PIRVN12_13465(hxlA)
RULUC8_20370(hxlA)
RMLFF011L_43020(hxlA)
ROLCA51_14720(hxlA)
AHELQ31a_23230(rmpA)
RLCK227x_16680(hxlA)
LPAVPLANPX_2556
GMRGmarT_59230(hxlA)
GIMF1728_15900
GPNPan110_58500(hxlA)
TIMGMBLW1_21350
KSTKSMBR1_1055
BROCIPI25_12570
BPITBPIT_02080
JETL3J17_12540
HBSIPV69_02725
UAMUABAM_03098
BHCJFL75_16590
TRSTerro_1472
TALBFTW19_05085
EDAGWR55_03245
ABACLuPra_03104(hxlA)
STRSterm_1849 Sterm_3212
RBARAWN76_010760
CPICpin_5671
CHIHGWR21_16300
ARACE0W69_006905
FLNFLA_3348
FLCKJS93_07410
PEPAQ505_07150
PCMAY601_4886
PSTYBFS30_16375
PROEH9L23_01690
PMUOLOK61_01885
MUPA0256_03165
MRUBDEO27_000305
MGOSDIU38_016630
AGDFRZ59_01495
CMRCycma_4041
CAMUCA2015_3993
EVIEchvi_3532
EMAIKZP23_17980
ALMAO498_04580
SPIKEXU85_08270
SPIBG8759_32855
RHOZGXP67_03990
ALSDJ013_10535
PKOPKOR_19965
ADDHUW48_11525
ASWUHUW51_20280
FCRHYN56_16620(hxlA)
ZPRZPR_1061
MARMYQ22_17840
CAOCelal_3937
CBALM667_16185
CBATM666_16170
ZGAZOBELLIA_3942(hxlA)
AALGAREALGSMS7_04556(hxlA)
LPALLDL79_02280
CBENEG339_11265(hxlA)
MPGTheba_2591
ALAMRT761_00648
DPBBABL1_gene_664(hxlA)
CDESC0J27_01395
VPMKG892_00070
MJAMJ_0644 MJ_1447
MFEMefer_0259 Mefer_1012
MVUMetvu_0541 Metvu_1176
MFSMFS40622_0906 MFS40622_1056
MIFMetin_1286 Metin_1445
MJHJH146_0570 JH146_0865
MESGMLAUSG7_0043 MLAUSG7_1449(fae-hps)
MESAMLASG1_0987(fae-hps) MLASG1_1223
MIGMetig_0604 Metig_0664
MMPMMP1270
MMQMmarC5_0321
MMXMmarC6_1403
MMZMmarC7_0516
MMDGYY_07185
MMAKMMKA1_14950
MMAOMMOS7_13770
MMADMMJJ_15750(hxlA)
MAEMaeo_0614 Maeo_1123
MVNMevan_0582
MOKMetok_0605 Metok_1249
METFCFE53_02965 CFE53_04300
MTHMTH_1474 MTH_888
MMGMTBMA_c00570(fae_hps) MTBMA_c12830
MWOMWSIV6_0011(fae-hps) MWSIV6_1262(hpsA)
MTEEMTTB_00460 MTTB_04920
METCMTCT_0805 MTCT_1339
METEtca_00853(proA) tca_01421(fae)
METZMETMT2_0957 METMT2_1368
METKFVF72_04250 FVF72_07115
MTHMFZP57_00015 FZP57_06005
METJFZP68_01675
MSTMsp_1358 Msp_1498
METBAW729_07875 AW729_08735
MRUmru_0712 mru_2131
MSIMsm_0426 Msm_1213
MEBAbm4_0046 Abm4_0441
MMILsm9_0074 sm9_0586
MEYETL18_02745 TL18_10355
MOLYLM1_0353 YLM1_1686
MAROMarbSA_11880 MarbSA_18020
METVK4897_02645 K4897_05320
MELMetbo_0071 Metbo_2333
MEWMSWAN_0017 MSWAN_0326
METHMBMB1_0009(fae-hps) MBMB1_0388
MFCBRM9_0060 BRM9_1874
MFIDSM1535_0057 DSM1535_1378(fae-hps)
MCUBMCBB_0021(fae-hps_1)
MSUBBK009_09760 BK009_12115
METNBK008_05430 BK008_07745
METTCIT01_02340 CIT01_05685(fae)
METOCIT02_04870 CIT02_07030(fae)
MEMEHYG87_03735 HYG87_06650
MFVMfer_0465 Mfer_0572
MKAMK0153(sgbH) MK1449(menG)
AFUAF_0861 AF_1305
AFGAFULGI_00009430 AFULGI_00014160
APOArcpr_1052 Arcpr_1797
AVEArcve_1411 Arcve_1683
ASTAsulf_00326 Asulf_01087
FPLFerp_2129 Ferp_2198
GACGACE_0250 GACE_2158
GAHGAH_00051 GAH_00575
PFUPF0220
PFIPFC_00160
PHOPH1938(PH1938)
PABPAB1222
PYNPNA2_0868
PYAPYCH_13020
PYSPy04_0376
PYCTQ32_01240
TKOTK0475
TONTON_0336
TGATGAM_1891(hps)
TSITSIB_0428
TBATERMP_00758
THEGQS_03555
THATAM4_82
THMCL1_0365
TLTOCC_09933
THSTES1_0756
TNUBD01_0222
TEUTEU_06790
TGYX802_02210
THVADU37_CDS03570
TPEPA0127_02350
TPIEA7C91_07685
TGGA3K92_01750
TCEA3L02_00185
TBSA3L01_02370
THHCDI07_02325
TSLA3L11_06255
TTDA3L14_03835
TPRFA3L09_00545
TRLA3L10_04210
TPAFA3L08_04625
THYA3L12_06325
TICFH039_04545(hxlA)
TCQTIRI35C_0698
THEMFPV09_04565(hxlA)
THEIK1720_05250(hxlA)
PPACPAP_05755
MBAMbar_A0935 Mbar_A1170
MBYMSBRM_0067 MSBRM_3392
MBWMSBRW_0061 MSBRW_3553
MBARMSBR2_2313 MSBR2_3345
MBAKMSBR3_2375 MSBR3_3372
MACMA_4504 MA_4608
MMAMM_1215 MM_1279
MMAZMmTuc01_1255 MmTuc01_1325
MMJMSMAS_0037 MSMAS_0097
MMACMSMAC_0037 MSMAC_0105
MVCMSVAZ_0074 MSVAZ_0103
MEKMSKOL_0070 MSKOL_0099
MLSMSLAZ_0035 MSLAZ_3053
METMMSMTP_0040 MSMTP_0201
MEFMSWH1_0036 MSWH1_3047
MEQMSWHS_0037 MSWHS_1919
MSJMSSAC_0046 MSSAC_4300
MSZMSSIH_0039 MSSIH_3802
MSWMSSIT_0039 MSSIT_3879
MTHRMSTHT_1664 MSTHT_1787
MTHEMSTHC_1499 MSTHC_1625
MHORMSHOH_0037 MSHOH_0117
MFZAOB57_007440 AOB57_008160
MBUMbur_1994(fae-hps)
MMETMCMEM_0222 MCMEM_0644
MELOJ7W08_01295 J7W08_11180
MMHMmah_0234 Mmah_1222
MHAZBHR79_02340 BHR79_07435
MEVMetev_0697 Metev_1698
MZHMzhil_0262 Mzhil_0311
MPYMpsy_1396 Mpsy_1425
MZIHWN40_01665 HWN40_01805
MHZMetho_0261 Metho_0283
MTPMthe_0455 Mthe_0988
MCJMCON_0429 MCON_1383
MHIMhar_0019 Mhar_1869
MHUMhun_0647 Mhun_1628
MRTJKHC33_06360 KHC33_10130
MLAMlab_0996 Mlab_1453
MEMMemar_0744 Memar_1085
MBGBN140_1075 BN140_1140
MEMAMMAB1_1386(fae-hps) MMAB1_1456(hpsA)
MCHKMchiMG62_08670 MchiMG62_12270(fae)
MPIMpet_0679 Mpet_0801
MENDL6E24_05200 L6E24_11130
MBNMboo_0707 Mboo_0772
MFOMetfor_2057 Metfor_2503
MPLMpal_1036 Mpal_2121
MPDMCP_0861 MCP_2904(fae_hps)
MEZMtc_0381(fae) Mtc_1411
RCIRCIX1492 RCIX775(fae-hps)
HARAAArcS_1663
MELUMTLP_05990(fae_1) MTLP_12130
MEAMMU439_01845 MU439_06385
TARTALC_01565
MAXMMALV_16840
MERMMINT_19420
MEARMpt1_c14440(faeB)
MEUZKRP56_00255
MARCAR505_0014
ABIAboo_0457
ACFAciM339_0590
APEAPE_0952.1(hxlA)
ACJACAM_0624(hxlA)
SMRSmar_0492
SHCShell_0310
IHOIgni_0269
IISEYM_01130
DKADKAM_1456
DFDDesfe_0079
DMUDesmu_0149
TAGTagg_1068
IAGIgag_1921
THGTCELL_0740
HBUHbut_0129
PFMPyrfu_0648
PDLPyrde_0680
STOSTK_02380(hxlA)
SOHD1869_00695(hxlA)
SSOSSO0202(hpS-2)
SOLSsol_1184
SSOASULA_1220
SSOLSULB_1221
SSOFSULC_1219
SSHIJ5U23_00054
SCASSACC_01190
SAISaci_0802
SACNSacN8_03890
SACRSacRon12I_03880
SACSSUSAZ_03625
SISLS215_2094
SIAM1425_1931
SIMM1627_2009
SIDM164_1939
SIYYG5714_2053
SINYN1551_0865
SIILD85_2191
SIHSiH_1876
SIRSiRe_1804
SICSiL_1785
SULABFU36_04900
SULEGFS03_10600
SULOGFS33_02415
SULLEWF20_02130(hxlA)
MSEMsed_0227
MEMJMJ1HA_0312
MCNMcup_1845
MHKDFR87_05610
MPRUDFR88_05485
MTENGWK48_05945
MJNMjAS7_0813
AHOAhos_0599
AMANB6F84_07975
ABRIDFR85_06830
ASULDFR86_07010
AAMBD1866_10735
ACIHHS5_20010
SACDHS1genome_0892
SAZOD1868_00970
CSTYKN1_17010
STEPIC006_1852
SAHSHS7_17030
PAIPAE1679
PISPisl_1686
PCLPcal_0568
PASPars_1830
PYRP186_0040
POGPogu_0300
TNETneu_0708
PYWPYWP30_00751
CMACmaq_1871
TTNTTX_1521(hps)
TUZTUZN_2015
VDIVdis_1817
VMOVMUT_0258
TPETpen_0372
THBN186_02880
TCBTCARB_1644
THELIG193_05685
ASCASAC_0959
ACIASE86_04960
CLGCalag_0067
FFOFFONT_0403
NCVNCAV_0256
CCAINAS2_0542
KCRKcr_1307
BARCAOA65_1083(faeB-hpsB)
BARBAOA66_0495 AOA66_1278
FLTSv326_0214 Sv326_0884
LOKILokiarch_06870 Lokiarch_17920 Lokiarch_47420
PSYTDSAG12_03237(faeB-hpsB)
 » show all
Reference
1  [PMID:4219834]
  Authors
Ferenci T, Strom T, Quayle JR
  Title
Purification and properties of 3-hexulose phosphate synthase and phospho-3-hexuloisomerase from Methylococcus capsulatus.
  Journal
Biochem J 144:477-86 (1974)
DOI:10.1042/bj1440477
Reference
2  [PMID:564713]
  Authors
Kato N, Ohashi H, Tani Y, Ogata K
  Title
3-Hexulosephosphate synthase from Methylomonas aminofaciens 77a. Purification, properties and kinetics.
  Journal
Biochim Biophys Acta 523:236-44 (1978)
DOI:10.1016/0005-2744(78)90026-8
Reference
3  [PMID:8595859]
  Authors
Yanase H, Ikeyama K, Mitsui R, Ra S, Kita K, Sakai Y, Kato N
  Title
Cloning and sequence analysis of the gene encoding 3-hexulose-6-phosphate synthase from the methylotrophic bacterium, Methylomonas aminofaciens 77a, and its expression in Escherichia coli.
  Journal
FEMS Microbiol Lett 135:201-5 (1996)
DOI:10.1111/j.1574-6968.1996.tb07990.x
  Sequence
Reference
4  [PMID:16278835]
  Authors
Yurimoto H, Kato N, Sakai Y
  Title
Assimilation, dissimilation, and detoxification of formaldehyde, a central metabolic intermediate of methylotrophic metabolism.
  Journal
Chem Rec 5:367-75 (2005)
DOI:10.1002/tcr.20056
Reference
5  [PMID:16428816]
  Authors
Kato N, Yurimoto H, Thauer RK
  Title
The physiological role of the ribulose monophosphate pathway in bacteria and archaea.
  Journal
Biosci Biotechnol Biochem 70:10-21 (2006)
DOI:10.1271/bbb.70.10
Reference
6  [PMID:15901685]
  Authors
Orita I, Yurimoto H, Hirai R, Kawarabayasi Y, Sakai Y, Kato N
  Title
The archaeon Pyrococcus horikoshii possesses a bifunctional enzyme for formaldehyde fixation via the ribulose monophosphate pathway.
  Journal
J Bacteriol 187:3636-42 (2005)
DOI:10.1128/JB.187.11.3636-3642.2005
  Sequence
[pho:PH1938]
Reference
7
  Authors
Kato, N., Miyamoto, N., Shimao, M. and Sakazawa, C.
  Title
3-Hexulose phosphate pynthase from a new facultative methylotroph, Mycobacterium gastri MB19.
  Journal
Agric Biol Chem 52:2659-2661 (1988)
Other DBs
ExplorEnz - The Enzyme Database: 4.1.2.43
IUBMB Enzyme Nomenclature: 4.1.2.43
ExPASy - ENZYME nomenclature database: 4.1.2.43
BRENDA, the Enzyme Database: 4.1.2.43

DBGET integrated database retrieval system