KEGG   ENZYME: 4.2.1.156
Entry
EC 4.2.1.156                Enzyme                                 
Name
L-talarate dehydratase;
L-talarate hydro-lyase
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
Sysname
L-altarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming)
Reaction(IUBMB)
L-altarate = 5-dehydro-4-deoxy-D-glucarate + H2O [RN:R11075]
Reaction(KEGG)
R11075
Substrate
L-altarate [CPD:C21088]
Product
5-dehydro-4-deoxy-D-glucarate [CPD:C00679];
H2O [CPD:C00001]
Comment
Requires Mg2+. The enzyme, isolated from the bacteria Salmonella typhimurium and Polaromonas sp. JS666, also has activity with galactarate (cf. EC 4.2.1.42, galactarate dehydratase).
History
EC 4.2.1.156 created 2015
Orthology
K20023  L-talarate/galactarate dehydratase
Genes
EFE: EFER_1473
STY: STY4099
STT: t3822
SEX: STBHUCCB_40340
SENT: TY21A_19420
STM: STM3697
SEO: STM14_4457
SEV: STMMW_36851
SEY: SL1344_3662
SEM: STMDT12_C37540
SEJ: STMUK_3683
SEB: STM474_3870
SEF: UMN798_4016
SETU: STU288_18680
SETC: CFSAN001921_21960
SENR: STMDT2_35811
SEND: DT104_36801
SENI: CY43_19185
SEEN: SE451236_02435
SPT: SPA3549
SEK: SSPA3312
SPQ: SPAB_04594
SEC: SCH_3621(yin)
SEH: SeHA_C4022
SHB: SU5_04174
SENH: CFSAN002069_13555
SEEH: SEEH1578_04570
SEE: SNSL254_A3977
SENN: SN31241_1830
SEA: SeAg_B3915
SENS: Q786_18075
SED: SeD_A4083
SEG: SG3734
SEL: SPUL_3867
SEGA: SPUCDC_3853
SET: SEN3519
SENA: AU38_17975
SENO: AU37_18165
SENV: AU39_18170
SENQ: AU40_20245
SENL: IY59_18610
SEEC: CFSAN002050_25455
SEEB: SEEB0189_001380
SEEP: I137_18555
SENB: BN855_37920
SENE: IA1_17970
SENC: SEET0819_02245
SES: SARI_03944
SALZ: EOS98_00750
ENR: H650_02680
ENF: AKI40_3173
KVA: Kvar_2413
KPE: KPK_2460
KPK: A593_24325
KVD: KR75_22265
KVQ: SP68_03000
KOX: KOX_19905
KOE: A225_2851
KOY: J415_17725
KOM: HR38_18235
KOK: KONIH1_13975
KOC: AB185_22085
KQV: B8P98_13040
KLL: BJF97_14135
KLW: DA718_13910
KAR: LGL98_11520
KGR: JJJ10_14785
KPAS: LUW96_20430
KLC: K7H21_13640
KLM: BWI76_13570
RON: TE10_13620
RPLN: B1209_14000
RTG: NCTC13098_03845(rhmD_2)
CRO: ROD_42111
CBRA: A6J81_04480
CWE: CO701_10195
CYO: CD187_11675
CPOT: FOB25_23225
CFQ: C2U38_11960
CAMA: F384_07290
CIF: AL515_12340
CFAR: CI104_13290
CPAR: CUC49_08055
CTEL: GBC03_17215
CARS: E1B03_13505
CIB: HF677_011720
KSA: C813_03310
KOR: AWR26_12660
KRD: A3780_11390
KPSE: IP581_11405
KOO: O9K67_12340
SYM: K6K13_04780
ASUB: NLZ15_06270
KIN: AB182_12420
PDZ: HHA33_15045
METY: MRY16398_29200
PSGC: G163CM_11410
SUPE: P0H77_10915
TOE: QMG90_02440
EBC: C2U52_23330
GQU: AWC35_22925
ECA: ECA0998
PATR: EV46_05095
PATO: GZ59_10330(lfeW)
PCT: PC1_0918
PCC: PCC21_009410
PWA: Pecwa_3386
PPAR: A8F97_01720
PEC: W5S_3388
PWS: A7983_13740
PPOA: BJK05_21625
PBRA: B5S52_16950
PPUJ: E2566_05250
PARI: I2D83_17385
PVZ: OA04_10500(talD)
PPAV: LOZ86_17050
PPOO: LW347_05210
PCAC: OI450_16390
PACB: M9782_07155
DDD: Dda3937_02647(lfeW)
DZE: Dd1591_3561
DDC: Dd586_0512
DZC: W909_02680
DSO: A4U42_11735
CED: LH89_09595
DFN: CVE23_02720
DDQ: DDI_0313
DDA: Dd703_2476
SOD: Sant_2144
PAM: PANA_1262(mdlA)
PLF: PANA5342_3023(mdlA1)
PAJ: PAJ_0583(mdlA)
PAQ: PAGR_g2896
PAO: Pat9b_5240
PMK: MDS_1245
PFV: Psefu_1619
POR: APT59_05475
PFE: PSF113_5900
PCG: AXG94_15245
PSES: PSCI_1981
PALL: UYA_05665
PPSH: G5J76_15315
PSEJ: HNQ25_18460 HNQ25_18470
PVK: EPZ47_29775
PEZ: HWQ56_10270
PKH: JLK41_06330 JLK41_06340
PTY: JWV26_16575
PMAO: PMYSY11_1234
PVW: HU752_021755
PXA: KSS93_15770
PPRG: HU725_022740
PFAK: KSS94_11635 KSS94_12435
PALV: KSS97_25235
PZA: HU749_000770
PCAS: LOY40_25120
PSR: PSTAA_4005
PSC: A458_01930
PSH: Psest_0369
PSTT: CH92_11115
PSED: DM292_21105
PCHL: LLJ08_01890
PKG: LW136_01895
PZD: KQ248_15755
KUS: B9G99_15910
KMA: B9H00_15725
SAJS: QO259_10910
RPJ: N234_26270
REU: Reut_B4643
CBW: RR42_s0382
CGD: CR3_3082
CPAU: EHF44_26465
COX: E0W60_09115
CCAM: M5D45_07670
CCAX: KZ686_20555
BCT: GEM_3437
BGO: BM43_2754
BGP: BGL_2c12620
BPLA: bpln_2g13430
PCAF: DSC91_001114 DSC91_007322
PLG: NCTC10937_00398(mdlA_1)
CABA: SBC2_17980
BGM: CAL15_01490 CAL15_19280
ACHB: DVB37_23635
ACHO: H4P35_21850
AMUI: PE062_18460
ODI: ODI_R0434
PACR: FXN63_20655
PARK: LSG25_00600
RHY: RD110_20190
POL: Bpro_0435
ACIO: EAG14_06870
DAC: Daci_4290
DEL: DelCs14_2561
DTS: BI380_07215
DHK: BO996_19130
DLA: I6G47_02915
LIH: L63ED372_02032(mdlA_1)
KIA: G8A07_05140
MIU: ABE85_11800
HFR: G5S34_19205
MASW: AM586_05720
MFY: HH212_21780
RGU: A4W93_05245
XYK: GT347_00410
ATF: Ach5_49330
AVQ: HRR99_16005
ALEG: CFBP4996_26775
RLE: pRL120237
RLT: Rleg2_5408
RLG: Rleg_5348
RLB: RLEG3_09795
RLU: RLEG12_04095
RAD: CO657_26630
RII: FFM53_025550
RHID: FFM81_023785
RRG: J3P73_26305
RLW: RlegWSM1455_24705
RBW: RLCC275e_24430
BGQ: X265_38085
BGZ: XH91_37285
BOF: FQV39_32755
MET: M446_3263
MNO: Mnod_4686
MMES: MMSR116_02235 MMSR116_22195
MTAD: M6G65_04075
CMET: K6K41_09585
OCD: FHY55_19090
PLIA: E4191_18145
PSAP: JHX88_10760
NHUM: PQ457_21330
SNAP: PQ455_04940
SYA: A6768_07000
RAP: RHOA_3354
AZL: AZL_c03560
SRAT: FY406_02030
TOO: C7K38_01945
MSM: MSMEG_0126
MSG: MSMEI_0122
MSB: LJ00_00635
MSN: LI99_00635
MSH: LI98_00635
MMAT: MMAGJ_21640
MSEI: MSEDJ_14380
MGO: AFA91_07525
CAMG: CAMM_01125
NAH: F5544_18975
RHB: NY08_3282
RFA: A3L23_01457
RHS: A3Q41_01900
RPSK: JWS13_29365
SVL: Strvi_5174
SHY: SHJG_0937
SHO: SHJGH_0770
SRC: M271_46835
SMAL: SMALA_0245
SSOI: I1A49_04690
SBH: SBI_09219
SLC: SL103_30815
SAUO: BV401_04995
STRO: STRMOE7_24645
SPAD: DVK44_30290
SBAT: G4Z16_06570
SDW: K7C20_23670
SXN: IAG42_04720
STUB: MMF93_32870
SLON: LGI35_40510
SANT: QR300_39715
AARC: G127AT_14870
GSD: M3M28_05315
ART: Arth_0032
ARR: ARUE_c00340(mdlA1)
ARW: MB46_17665
ARZ: AUT26_00175
ARQ: BWQ92_10210
ARN: CGK93_00185
ARX: ARZXY2_3859
ACRY: AC20117_05410
ARTH: C3B78_00150
ASUF: MNQ99_02705
AOD: Q8Z05_08150
AAU: AAur_0037(clcB)
PUE: FV140_00175
PNV: JMY29_00175
ACH: Achl_0038
APN: Asphe3_00320
PSUL: AU252_10170
PSNI: NIBR502771_05115
PSEY: GU243_15790
PDEL: JCQ34_00155
GAR: AOZ07_14355
GLU: F0M17_13710
GMI: NMP99_14330
GMY: XH9_11705
GNC: QQS42_14110
KRS: EQG70_16170
PAEY: KUF55_16355
BRX: BH708_04290
BGG: CFK41_08100
BSAU: DWV08_06075
BKI: M4486_15770
BRHA: NLU66_01850
IDO: I598_2363(mdlA)
JME: EEW87_17150
BLY: A2T55_01740
BSPO: L1F31_01330
AUS: IPK37_06075
PACD: EGX94_12185
PAUS: NCTC13651_01417(mdlA_1)
MPH: MLP_05990
MIK: FOE78_11195
MICG: GJV80_21615
PRV: G7070_00710
NPI: G7071_04380
NAQU: ENKNEFLB_04210
NRO: K8W59_16210
MGG: MPLG2_3242
KQI: F1D05_09810
NDA: Ndas_1050
NAKE: KGD83_20390
NCG: KGD84_19405
SNAH: OUQ99_02730
SAIU: J4H86_24440
AMAZ: LUW76_43495
NOA: BKM31_27070 BKM31_27075
NOW: GBF35_19210 GBF35_19215
NCX: Nocox_19015(mdlA2)
NGN: LCN96_19505 LCN96_19510
GOB: Gobs_2394
BSD: BLASA_1681(mdlA)
SEN: SACE_4598
AAB: A4R43_10120
AMYY: YIM_26245(mdlA2)
AACD: LWP59_20520
ATHM: L1857_24995
APRE: CNX65_20240
AMI: Amir_4042
SSYI: EKG83_18845
AHM: TL08_16165
ACTI: UA75_05550
ACAD: UA74_05545
PMAD: BAY61_06940
CROS: N8J89_19385
ASG: FB03_06945
FTJ: FTUN_0818
TSPH: KIH39_25300
 » show all
Reference
1  [PMID:17649980]
  Authors
Yew WS, Fedorov AA, Fedorov EV, Almo SC, Gerlt JA
  Title
Evolution of enzymatic activities in the enolase superfamily: L-talarate/galactarate dehydratase from Salmonella typhimurium LT2.
  Journal
Biochemistry 46:9564-77 (2007)
DOI:10.1021/bi7008882
  Sequence
[stm:STM3697]
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.156
IUBMB Enzyme Nomenclature: 4.2.1.156
ExPASy - ENZYME nomenclature database: 4.2.1.156
BRENDA, the Enzyme Database: 4.2.1.156

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Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (884)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (354)   
   KEGG MGENES (229)   
   RefGene (300)   
Protein sequence (120)   
   UniProt (119)   
   SWISS-PROT (1)   
DNA sequence (73)   
   GenBank (39)   
   EMBL (34)   
Protein domain (8)   
   InterPro (8)   
All databases (1090)   

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