KEGG   ENZYME: 4.2.1.43
Entry
EC 4.2.1.43                 Enzyme                                 
Name
2-dehydro-3-deoxy-L-arabinonate dehydratase;
2-keto-3-deoxy-L-arabinonate dehydratase;
2-dehydro-3-deoxy-L-arabinonate hydro-lyase
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
Sysname
2-dehydro-3-deoxy-L-arabinonate hydro-lyase (2,5-dioxopentanoate-forming)
Reaction(IUBMB)
2-dehydro-3-deoxy-L-arabinonate = 2,5-dioxopentanoate + H2O [RN:R02278]
Reaction(KEGG)
R02278
Substrate
2-dehydro-3-deoxy-L-arabinonate [CPD:C00684]
Product
2,5-dioxopentanoate [CPD:C00433];
H2O [CPD:C00001]
History
EC 4.2.1.43 created 1972
Pathway
ec00053  Ascorbate and aldarate metabolism
ec01100  Metabolic pathways
Orthology
K13876  2-keto-3-deoxy-L-arabinonate dehydratase
Genes
CTUCTU_06570
KMIVW41_03260
CAFAL524_22380
EBTEBL_c33280
KCOBWI95_18060
BUFD8682_18995
BAGEBADSM9389_06400
BFTMNO13_03305
SPESpro_0707
SLQM495_02890
SQUE4343_13080
ROXBV494_01165
RVCJ9880_24230
SODSant_0675
EPECI789_02275
HAVAT03_19840
HPARAL518_06710
OPODSM2777_05585
LPVHYN51_09415
PRAGEKN56_20130
RFOREIFOR_01233
LLPGH975_02685
RPIRpic_3006
RPFRpic12D_2596
RPJN234_21925
RMNTK49_06590
REHH16_B0213(dapA2)
CNCCNE_2c01980(dapA1)
CUHBJN34_21090
CTIRALTA_B0220
CBWRR42_s0473
CGDCR3_3974(araD)
CCUPBKK81_02470
CPAUEHF44_25915
COXE0W60_07020
BTEBTH_II1630
BTQBTQ_4919(araD)
BTJBTJ_3543(araD)
BTZBTL_4392(araD)
BTDBTI_5591(araD)
BTVBTHA_3565(araD)
BTHEBTN_4043(araD)
BTHMBTRA_4050(araD)
BTHADR62_4079
BTHLBG87_4375(AraD)
BHGI6G56_24130
BVIBcep1808_3834
BVEAK36_4877(araD)
BURBcep18194_B0042 Bcep18194_B3057
BCMBcenmc03_4375 Bcenmc03_4586 Bcenmc03_6235
BCHBcen2424_5643 Bcen2424_5804 Bcen2424_6637
BCJBCAM0104 BCAM2800
BCENDM39_5046(araD) DM39_6177(araD)
BCEWDM40_3367(araD)
BCEOI35_6679
BAMBamb_3398 Bamb_4923
BACBamMC406_3210 BamMC406_5478
BMJBMULJ_05321(dapA)
BMUBmul_3204
BMKDM80_4584(araD)
BMULNP80_3349(araD)
BCTGEM_3979 GEM_5481 GEM_5607
BCEDDM42_5188(araD)
BCEPAPZ15_24595
BDLAK34_5007(araD)
BPYRABD05_20735 ABD05_21635 ABD05_31625
BCONNL30_17845 NL30_24965
BUBBW23_3987(araD) BW23_4351(araD)
BDFWI26_15735 WI26_26560
BLATWK25_29415
BTEIWS51_10640
BSEMWJ12_16065 WJ12_33860
BPSLWS57_00265 WS57_05740
BMECWJ16_20380 WJ16_32370
BSTGWT74_22175 WT74_32755
BSTLBBJ41_21670
BANNJFN94_18020 JFN94_18890 JFN94_26305
BGLbglu_1g17850
BGUKS03_2640(araD)
BUGBC1001_4105
BGFBC1003_5311
BGDbgla_2g13470
BGOBM43_5015(araD)
BYIBYI23_B013290 BYI23_D004040 BYI23_D009640
BUKMYA_3489
BUEBRPE67_BCDS00220 BRPE67_DCDS05750 BRPE67_DCDS11690
BULBW21_5279(araD)
BUQAC233_29080
BGPBGL_1c19710
BPLAbpln_1g18020
BUDAQ610_26805
BUMAXG89_11870 AXG89_22230
BUIAX768_05665 AX768_24750
BURKDM992_25760 DM992_26925 DM992_37145
BPHBphy_6711
BGEBC1002_4374
BPXBUPH_00687
BPYBphyt_4575
BFNOI25_5423 OI25_6642
BCAIK788_0005071 K788_0008592
PSPWBJG93_24260
PARABTO02_21210
PARBCJU94_24595 CJU94_26045
PHSC2L64_22580 C2L64_36150 C2L64_52290
PTERC2L65_25020 C2L65_31360
PGPCUJ91_27135
PCJCUJ87_17870
PTSCUJ90_19400
PCAFDSC91_000932 DSC91_002982
PMEGFNZ07_06590
PTROG5S35_23715 G5S35_32515 G5S35_33960
PGISI6I06_18090 I6I06_25055
PACPFAZ97_24140 FAZ97_34310
PACSFAZ98_28815
PEWKZJ38_22555
CABASBC2_14340(dapA_3) SBC2_66650(araD)
BUOBRPE64_BCDS00230 BRPE64_CCDS05510 BRPE64_DCDS07830
BHOD560_1639
BHMD558_1627
BBROBAU06_17390
BFZBAU07_05105
BPDZBBN53_13505
AXYAXYL_04351
AXONH44784_063331
AXNAX27061_4574
AXXERS451415_04605(yagE_2)
ADTAPT56_21015
AISBUW96_10930
ASWCVS48_23105
ACHRC2U31_09970 C2U31_16375
ACHBDVB37_17495
ADYHLG70_02415
CDNBN940_14416
ODIODI_R4258
PARKLSG25_17845
RFRRfer_0453
RSBRS694_18415
RHYRD110_12005
POLBpro_2837
PVACHC248_02301(araD)
AAVAave_2247
AAAAcav_2893 Acav_4648
ACKC380_10450
ACIOEAG14_03785
AMONH9L24_15665
AANTHUK68_00055
ARADKI609_13600
VEIVeis_2707 Veis_3541
DACDaci_4983
DELDelCs14_1862
DTSBI380_30715
DHKBO996_22910
DLAI6G47_31125
VAPVapar_1052
VPEVarpa_1121
VPDVAPA_1c11050 VAPA_2c00550(dapA)
VAAAX767_04455
VBOCKY39_05220
VAMC4F17_13930
CTTCtCNB1_3908
CTESO987_23535
HPSEHPF_09020(araD)
RDPRD2015_2629
ATERMW290_14215 MW290_26310
HSEHsero_1368(dapA)
HSZACP92_06865
HHTF506_04770
HRBHrubri_1189(dapA)
HEEhmeg3_00985
HHFE2K99_06845
HFRG5S34_07085
GLCJQN73_14925
XYKGT347_21915
URUDSM104443_00662(araD_1)
MESMeso_3971
AAKAA2016_4939
AMIHCO731_04159(yagE_2)
RPODE0E05_09145
ORMHTY61_17225
SMXSM11_pC1295
SMERDU99_23820
SIXBSY16_5632
EADOV14_a1105(dapA)
RHRCKA34_25505
SHZshn_14790
BJAbll7953(bll7953)
BJUBJ6T_12720
BJPRN69_06220
BRABRADO1813
BBTBBta_2133
BRSS23_65840
AOLS58_57230
BRCBCCGELA001_04085 BCCGELA001_29135
BRADBF49_3436
BICLMTR13_30020
BROBRAD285_5472(araD)
BRKCWS35_02785
BOTCIT37_03940 CIT37_08040
BRQCIT40_29215
BGQX265_04835
BGZXH91_05125
BSYMCIT39_28240
BBETF8237_12250
BARHWN72_04140 WN72_09275
BVZBRAD3257_8478(araD)
BELBE61_14750(dapA)
BDGLPJ38_08405 LPJ38_36410
BSEPHAP48_0019235
BQBJ4P68_0022725
BOPAXW83_15040
BOSBSY19_2309 BSY19_4559
BVVBHK69_13550 BHK69_23230
BOIBLM15_13485 BLM15_28230
BOFFQV39_01140 FQV39_05845 FQV39_14530
XAUXaut_1021
SNOSnov_0118
STARG3545_22980
APRAG3A50_11630
APOLK9D25_15455
MRDMrad2831_4925
MORMOC_5613
MAQUMaq22A_c05765(dapA)
MPHYMCBMB27_04363
MEEDA075_26795
METXA3862_07295
MMESMMSR116_28745
MTEADK419_06420
MINDmvi_28100
MTADM6G65_22580
MOCBB934_07055
MIVC4E04_02010
BIDBind_3080
CHELAL346_04990
DEAFPZ08_12195
MMYRMXMO3_02356
HDIHDIA_0216(araD)
AALAIGS74_14615
AALMLUX29_16530
AUZSa4125_16180
NOHG5V57_05530
LAPACP90_11030
LABTFIU93_14080(araD1) FIU93_16605(araD2)
LAGGB0E33_22965
PHRC6569_02935
PSTGE8M01_07905
LIZLGH83_06415
ACUTMRB58_07415
SILSPOA0244
DSHDshi_2446
OAROA238_c12510
MALGMALG_03895 MALG_04381 MALG_04456
YPACCEW88_03665
YANAYJ57_10815
SULZC1J03_13130
SULDB5M07_05330
SINLDSM14862_02690(araD)
RIDRIdsm_01841(araD)
AHTANTHELSMS3_03458
SAGUCDO87_19365
THAACFI11_20005
OCDFHY55_19120
MALUKU6B_19310
PALXGQA70_14560
PDEPden_4666
PAMIJCM7686_3316
PYEA6J80_10095
PCONB0A89_02490
PZHCX676_00745
PAROCUV01_13830
PMUTDPM13_08295
PSANHGN31_05465
PTPRCA23_c06720 RCA23_c06790(dapA3) RCA23_c23430
RHCRGUI_3959
RMBK529_014365 K529_016090
LVSLOKVESSMR4R_03077(araD)
SALOEF888_19155
LITFPZ52_15850
PSHQF3W81_19105
PALWPSAL_020910(araD)
PPAFI8N54_02195
RBZB9057_15760
FAPGR316_11125
NOVTQ38_023065
SPHITS85_03755
ACRAcry_2738
AMVACMV_30670
RGIRGI145_17600
ROSCTJ15_16450
RMUCFOB66_22025
RMTIAI58_08570
RAPRHOA_2195
AZLAZL_e03630(dapA)
ALIAZOLI_p50377(araD)
ABSAZOBR_p440160
ABQABAZ39_31595
ABFAMK58_27385
ATIAL072_31000
AHUA6A40_14230
AZTTSH58p_21360
AZMDM194_26435
AZZDEW08_22000
AOZHUE56_23205 HUE56_26165
SKTIGS68_08980 IGS68_30525
SMUCJL100_018400 JL100_031430
SROEJL101_017100 JL101_031855
HTQFRZ44_40650
NACINUH88_17205
NTRB0W44_15610
SRNA4G23_03540(dapA_3)
MOYCVS54_01202(araD)
HEAHL652_17435 HL652_17800
SATKSA2016_0951
BCVBcav_3940
MICGGJV80_08325
NOABKM31_21025
NAKEH165_10140
AABA4R43_04445
AMYYYIM_17550(araD)
AACDLWP59_14525
PAUTPdca_64040
ACTIUA75_20040
ACADUA74_19550
PMADBAY61_16470
PVSA1sIA79_05270
NHIB1s21160_02175
RULUC8_01250(araD)
ROLCA51_31580(dapA_3)
LCREPla8534_61970(araD)
AAGGETAA8_26400(araD)
PBSPlabr_4261
PLSVT03_23390(dapA_3)
FMRFuma_05619(araD)
GMRGmarT_22610(araD)
GIMF1728_03120
GPNPan110_21890(araD)
SDYNMal52_40300(araD_1) Mal52_45600(araD_2)
PLONPla110_17110(araD_1) Pla110_46420(araD_2)
PFERIRI77_21920 IRI77_22525
ABACLuPra_02639(araD_1)
FLASY85_11775
FLCKJS93_18565
CMRCycma_0043
SLISlin_0609
SRDSD10_11625
SPIKEXU85_24685
RUNDR864_11930 DR864_18420
RUPDTQ70_25045
FACFACI_IFERC01G0501
 » show all
Reference
1  [PMID:5954356]
  Authors
Stoolmiller AC, Abeles RH.
  Title
Formation of alpha-ketoglutaric semialdehyde from L-2-keto-3-deoxyarabonic acid and isolation of L-2-keto-3-deoxyarabonate dehydratase from Pseudomonas saccharophila.
  Journal
J Biol Chem 241:5764-71 (1966)
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.43
IUBMB Enzyme Nomenclature: 4.2.1.43
ExPASy - ENZYME nomenclature database: 4.2.1.43
BRENDA, the Enzyme Database: 4.2.1.43
CAS: 37263-10-8

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