KEGG   ENZYME: 4.2.2.9
Entry
EC 4.2.2.9                  Enzyme                                 
Name
pectate disaccharide-lyase;
pectate exo-lyase;
exopectic acid transeliminase;
exopectate lyase;
exopolygalacturonic acid-trans-eliminase;
PATE;
exo-PATE;
exo-PGL;
exopolygalacturonate lyase (ambiguous);
pelW (gene name);
pelX (gene name)
Class
Lyases;
Carbon-oxygen lyases;
Acting on polysaccharides
Sysname
(1->4)-alpha-D-galacturonan reducing-end-disaccharide-lyase
Reaction(IUBMB)
(1,4-alpha-D-galacturonosyl)n = (1,4-alpha-D-galacturonosyl)n-2 + 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate [RN:R02361 R06240]
Reaction(KEGG)
R02361 R06240(G)
Substrate
(1,4-alpha-D-galacturonosyl)n [CPD:C00470]
Product
(1,4-alpha-D-galacturonosyl)n-2;
4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate [CPD:C06118]
Comment
The enzyme catalyses the eliminative cleavage of an unsaturated disaccharide from the reducing end of homogalacturonan (the backbone of smooth regions of pectate, also known as de-esterified pectin).
History
EC 4.2.2.9 created 1972, modified 2002
Pathway
ec00040  Pentose and glucuronate interconversions
ec01100  Metabolic pathways
Orthology
K01731  pectate disaccharide-lyase
K22994  pectate disaccharide-lyase
Genes
ECCc0323
EABECABU_c02850
ELCi14_0311
ELDi02_0311
ECANCWI88_22765
ENTEnt638_4134
EASEntas_4441
ENRH650_15125
ENFAKI40_4954
EHUD5067_0023365
KOXKOX_06695
KOEA225_5810
KOYJ415_03050
KOMHR38_05185
KOKKONIH1_29285
KOCAB185_07140
KLLBJF97_28845
KLWDA718_29440
KGRJJJ10_27690
RORRORB6_18635
RONTE10_02310
RAODSD31_25725
RTGNCTC13098_07214(pelX)
REEelectrica_05046(pelX)
KSAC813_15435
KORAWR26_24550
KRDA3780_24760
KCOBWI95_07865
KOTEH164_22305
KPSEIP581_23260
KOBHF650_24205
KIENCTC12125_03774(pelX)
KASKATP_45140
KLUK7B04_05140
LAXAPT61_22190
LEIC2U54_04755
LEHC3F35_11740
LEEDVA44_23660
LERGNG29_23015
LEAGNG26_22355
LPNUKQ929_20635
LAZA8A57_00130
LEFLJPFL01_4267
BAGEBADSM9389_41930
SYMK6K13_10740
IZHFEM41_05575
PSGCG163CM_35660(pelX)
EBFD782_4530
YPEYPO1723(kdgC)
YPKy1885
YPHYPC_2093(kdgC)
YPAYPA_1798
YPNYPN_1907
YPMYP_1748(pelW)
YPPYPDSF_1725
YPGYpAngola_A2644
YPZYPZ3_1982(pelW)
YPTA1122_17265
YPDYPD4_1533(pelW)
YPXYPD8_2019(pelW)
YPWCH59_111
YPJCH55_525
YPVBZ15_1826
YPLCH46_3400
YPSYPTB2358(pelW)
YPOBZ17_98
YPIYpsIP31758_1692
YPYYPK_1802
YPBYPTS_2432
YPQDJ40_4215
YPUBZ21_1644
YPRBZ20_3849
YPCBZ23_1930
YPFBZ19_1721
YENYE1886(kdgC)
YEPYE105_C1965
YEYY11_07571
YELLC20_03007
YEWCH47_1320
YETCH48_3593
YEFFORC2_2251
YEEYE5303_20681(kdgC)
YSIBF17_20920
YALAT01_227
YFRAW19_1431
YINCH53_4262
YKRCH54_231
YROCH64_775
YMADA391_10370
YHID5F51_07675
YCAF0T03_09890
YMOHRD69_14695
YASN0H69_13100
SFWWN53_25785
SFGAV650_21450
SERASer39006_002560 Ser39006_014590
SERQCWC46_02560 CWC46_14585
SOFNCTC11214_03558(pelX_3)
RAHRahaq_4460
RACEJHW33_24235
RAQRahaq2_4938
RAAQ7S_22851
ROXBV494_21955
RVCJ9880_22120
RBADH2866_18360
ECAECA2402(pelW) ECA4510(pelX)
PATREV46_11575 EV46_22450
PATOGZ59_21550(pelW) GZ59_46090(pelX)
PCTPC1_1908 PC1_4259
PCCPCC21_019680 PCC21_042370
PCVBCS7_09865 BCS7_21380
PWAPecwa_2201 Pecwa_4562
PPARA8F97_07605 A8F97_18635
PECW5S_2143 W5S_4748
PWSA7983_07710 A7983_18435
PPOABJK05_04570 BJK05_16445
PBRAB5S52_12135 B5S52_22085
PPUJE2566_10205 E2566_21650
PARII2D83_10380 I2D83_22075
PAQUDMB82_0011465 DMB82_0020540
PVZOA04_23530(pelW) OA04_45670(pelX)
PPAVLOZ86_00635 LOZ86_09635
PQUIG609_009430 IG609_020225
PPOOLW347_09980 LW347_21675
DDDDda3937_00143(pelX) Dda3937_03361(pelW)
DZEDd1591_1970 Dd1591_4196
DDCDd586_1962 Dd586_4161
DZCW909_10230 W909_20195
DSOA4U42_08850 A4U42_20320
CEDLH89_00845 LH89_12570
DFNCVE23_11925 CVE23_22315
DDQDDI_2102 DDI_4246
DAQDAQ1742_02459(pelW) DAQ1742_04477(pelX)
DICDpoa569_001819 Dpoa569_003915
DDADd703_2033 Dd703_3996
BGJAWC36_08305
BNGEH206_11725
BIZHC231_10285
EPECI789_19155
ERWIGN242_00350
ERPLJN55_00455
PALHB1H58_13815
PGZC2E15_14280
PCDC2E16_14360
MINTC7M51_02053(pelX)
MTHIC7M52_00789(pelX)
MSUMS1742
BSUNA4G13_06040
ASUAsuc_1469
VVYVVA1380 VVA1383
VVMVVMO6_04291 VVMO6_04295
VVLVV93_v1c42910 VV93_v1c42940
VPAVPA0086
VPBVPBB_A0079
VPKM636_07910
VPHVPUCM_20080
VEXVEA_000914
VFUvfu_B01220 vfu_B01227
VFLAL536_00985 AL536_01015
VGABSQ33_05600 BSQ33_05635
VSRVspart_02703(pelW) Vspart_02709(pelX)
VZIG5S32_19215 G5S32_19245
PPRPBPRB1725(PELX)
PGBH744_1c0411
PGHFH974_23475
GAPGAPWK_0007
BACAFAY30_24085
BHABH0494(pelX)
BKWBkAM31D_11885(pelX)
HLIHLI_08040
SEDDERJ70_07430
RMFD5E69_01130
CTHUHUR95_16465
PCXLPB68_01775
EFCEFAU004_00534
EFAUEFAU085_00472
EFUHMPREF0351_10547(fms12)
EFTM395_02570
EDULIU_03960
ELACI4Q40_02775
MPSMPTP_1486
MPXMPD5_0537
JEHEJN90_07475
CCBClocel_2642 Clocel_3380
CSRCspa_c44020(pelX)
CBUTATN24_17765
CRWCROST_043480
CFBCLFE_004550
CSSCst_c01730(pelX)
CSDClst_0166(pelA)
FPRFP2_32150
CLEClole_0686
CEWEKH84_06800
CPYCphy_3869
ACELacsn021_18180
EELEUBELI_00122
TITThit_1727
COWCalow_2109
HALSD7D81_06930
IFNGM661_04520
TSGHLK68_02840
ABRABN85302860
SXISXIM_19900
SPADDVK44_19990
SHARHUT13_08720
AGYATC03_04075
IVAIsova_1147
IDOI598_2859(pelX)
SKESked_26480
SANWG7063_10785
TBETrebr_2157
TRIDYE50_02030 DYE50_12275
SCDSpica_0639
FMOC4N19_12110
TTATheth_1384
 » show all
Reference
1  [PMID:14188174]
  Authors
MACMILLAN JD, VAUGHN RH.
  Title
PURIFICATION AND PROPERTIES OF A POLYGALACTURONIC ACID-TRANS-ELIMINASE PRODUCED BY CLOSTRIDIUM MULTIFERMENTANS.
  Journal
Biochemistry 3:564-72 (1964)
DOI:10.1021/bi00892a016
Reference
2  [PMID:10049400]
  Authors
Shevchik VE, Kester HC, Benen JA, Visser J, Robert-Baudouy J, Hugouvieux-Cotte-Pattat N
  Title
Characterization of the exopolygalacturonate lyase PelX of Erwinia chrysanthemi 3937.
  Journal
J Bacteriol 181:1652-63 (1999)
DOI:10.1128/JB.181.5.1652-1663.1999
  Sequence
Reference
3  [PMID:10383957]
  Authors
Shevchik VE, Condemine G, Robert-Baudouy J, Hugouvieux-Cotte-Pattat N
  Title
The exopolygalacturonate lyase PelW and the oligogalacturonate lyase Ogl, two cytoplasmic enzymes of pectin catabolism in Erwinia chrysanthemi 3937.
  Journal
J Bacteriol 181:3912-9 (1999)
DOI:10.1128/JB.181.13.3912-3919.1999
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 4.2.2.9
IUBMB Enzyme Nomenclature: 4.2.2.9
ExPASy - ENZYME nomenclature database: 4.2.2.9
BRENDA, the Enzyme Database: 4.2.2.9
CAS: 37290-87-2

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