KEGG   ENZYME: 4.2.3.13
Entry
EC 4.2.3.13                 Enzyme                                 
Name
(+)-delta-cadinene synthase
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-delta-cadinene-forming)
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate = (+)-delta-cadinene + diphosphate [RN:R02311]
Reaction(KEGG)
R02311
Substrate
(2E,6E)-farnesyl diphosphate [CPD:C00448]
Product
(+)-delta-cadinene [CPD:C06394];
diphosphate [CPD:C00013]
Comment
The sesquiterpenoid (+)-delta-cadinene is an intermediate in phytoalexin biosynthesis. Mg2+ is required for activity.
History
EC 4.2.3.13 created 1999 as EC 4.6.1.11, transferred 2000 to EC 4.2.3.13, modified 2011
Pathway
ec00909  Sesquiterpenoid and triterpenoid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K14183  (+)-delta-cadinene synthase
K22065  alpha-copaene/(+)-delta-cadinene synthase
Genes
PVY116142924 116142925 116143613
TCC18593708 18593709
GRA105768271 105768272 105768274 105768275 105768276 105768277 105781617 105784507 105786286 105786287
GHI107895205 107895206 107902908 107903499 107903500 107903503 107903504 107903509 107918736 107918747 107918752 107920688 107920690 107920806 107925546 107925552 107925569 107928183
GAB108449986 108450450 108463061
DZI111276466 111302285
APRC113865171 113865764
PDUL117612877 117624233 117625371 117625373 117625374 117625380 117625391 117625394 117626040
RCU8280754
JCU105633238
MESC110610066
QLO115957757
SSPL121767711 121804591
HAN110893972
ECAD122579485 122582366 122582808 122589930 122593044 122595886 122600560 122603684 122606741 122607025 122607026 122607586 122607680 122608278 122608352 122608388 122608534 122610384
MING122059343 122059440 122059484 122059709 122059711 122063385 122073609 122092325
TSS122652013 122652014 122652019 122659497 122659502
 » show all
Reference
1  [PMID:8554317]
  Authors
Chen XY, Chen Y, Heinstein P, Davisson VJ
  Title
Cloning, expression, and characterization of (+)-delta-cadinene synthase: a catalyst for cotton phytoalexin biosynthesis.
  Journal
Arch Biochem Biophys 324:255-66 (1995)
DOI:10.1006/abbi.1995.0038
  Sequence
Reference
2  [PMID:8728715]
  Authors
Davis EM, Tsuji J, Davis GD, Pierce ML, Essenberg M
  Title
Purification of (+)-delta-cadinene synthase, a sesquiterpene cyclase from bacteria-inoculated cotton foliar tissue.
  Journal
Phytochemistry 41:1047-55 (1996)
DOI:10.1016/0031-9422(95)00771-7
  Sequence
Reference
3
  Authors
Davis, G.D., Essenberg, M.
  Title
(+)-delta-Cadinene is a product of sesquiterpene cyclase activity in cotton.
  Journal
Phytochemistry 39:553-567 (1995)
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.13
IUBMB Enzyme Nomenclature: 4.2.3.13
ExPASy - ENZYME nomenclature database: 4.2.3.13
BRENDA, the Enzyme Database: 4.2.3.13
CAS: 166800-09-5

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