| Entry |
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| Name |
(+)-delta-cadinene synthase
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| Class |
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
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| Sysname |
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-delta-cadinene-forming)
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| Reaction(IUBMB) |
(2E,6E)-farnesyl diphosphate = (+)-delta-cadinene + diphosphate [RN: R02311]
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| Reaction(KEGG) |
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| Substrate |
(2E,6E)-farnesyl diphosphate [CPD: C00448]
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| Product |
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| Comment |
The sesquiterpenoid (+)-delta-cadinene is an intermediate in phytoalexin biosynthesis. Mg2+ is required for activity.
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| History |
EC 4.2.3.13 created 1999 as EC 4.6.1.11, transferred 2000 to EC 4.2.3.13, modified 2011
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| Pathway |
| ec00909 | Sesquiterpenoid and triterpenoid biosynthesis |
| ec01110 | Biosynthesis of secondary metabolites |
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| Orthology |
| K14183 | (+)-delta-cadinene synthase |
| K22065 | alpha-copaene/(+)-delta-cadinene synthase |
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| Genes |
| PVY: | 116142924 116142925 116143613 |
| GRA: | 105768271 105768272 105768274 105768275 105768276 105768277 105781617 105784507 105786286 105786287 |
| GHI: | 107895205 107895206 107902908 107903499 107903500 107903503 107903504 107903509 107918736 107918747 107918752 107920688 107920690 107920806 107925546 107925552 107925569 107928183 |
| GAB: | 108449986 108450450 108463061 |
| APRC: | 113865171 113865764 |
| PDUL: | 117612877 117624233 117625371 117625373 117625374 117625380 117625391 117625394 117626040 |
| SSPL: | 121767711 121804591 |
| ECAD: | 122579485 122582366 122582808 122589930 122593044 122595886 122600560 122603684 122606741 122607025 122607026 122607586 122607680 122608278 122608352 122608388 122608534 122610384 |
| MING: | 122059343 122059440 122059484 122059709 122059711 122063385 122073609 122092325 |
| TSS: | 122652013 122652014 122652019 122659497 122659502 |
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| Reference |
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| Authors |
Chen XY, Chen Y, Heinstein P, Davisson VJ |
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| Title |
Cloning, expression, and characterization of (+)-delta-cadinene synthase: a catalyst for cotton phytoalexin biosynthesis. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Davis EM, Tsuji J, Davis GD, Pierce ML, Essenberg M |
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| Title |
Purification of (+)-delta-cadinene synthase, a sesquiterpene cyclase from bacteria-inoculated cotton foliar tissue. |
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| Journal |
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| Sequence |
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| Reference |
3 |
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| Authors |
Davis, G.D., Essenberg, M. |
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| Title |
(+)-delta-Cadinene is a product of sesquiterpene cyclase activity in cotton. |
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| Journal |
Phytochemistry 39:553-567 (1995) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 4.2.3.13 |
| ExPASy - ENZYME nomenclature database: | 4.2.3.13 |
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