KEGG   ENZYME: 4.2.3.199
Entry
EC 4.2.3.199                Enzyme                                 

Name
(-)-5-epieremophilene synthase;
STPS1 (gene name);
STP2 (gene name);
STP3 (gene name)
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
(2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (-)-epieremophilene-forming]
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate = (-)-5-epieremophilene + diphosphate [RN:R12261]
Reaction(KEGG)
R12261
Substrate
(2E,6E)-farnesyl diphosphate [CPD:C00448]
Product
(-)-5-epieremophilene [CPD:C22045];
diphosphate [CPD:C00013]
Comment
The plant Salvia miltiorrhiza (danshen) produces three different forms of the enzyme, encoded by paralogous genes, that exhibit different spacial expression patterns and respond differently to hormone treatment.
History
EC 4.2.3.199 created 2018
Orthology
K23173  (-)-5-epieremophilene synthase
Reference
1  [PMID:28487717]
  Authors
Fang X, Li CY, Yang Y, Cui MY, Chen XY, Yang L
  Title
Identification of a Novel (-)-5-Epieremophilene Synthase from Salvia miltiorrhiza via Transcriptome Mining.
  Journal
Front Plant Sci 8:627 (2017)
DOI:10.3389/fpls.2017.00627
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.199
IUBMB Enzyme Nomenclature: 4.2.3.199
ExPASy - ENZYME nomenclature database: 4.2.3.199
BRENDA, the Enzyme Database: 4.2.3.199

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