KEGG   ENZYME: 5.3.1.35
Entry
EC 5.3.1.35                 Enzyme                                 

Name
2-dehydrotetronate isomerase;
otnI (gene name)
Class
Isomerases;
Intramolecular oxidoreductases;
Interconverting aldoses and ketoses, and related compounds
Sysname
2-dehydrotetronate isomerase
Reaction(IUBMB)
(1) 2-dehydro-L-erythronate = 3-dehydro-L-erythronate [RN:R11721];
(2) 2-dehydro-D-erythronate = 3-dehydro-D-erythronate [RN:R11722]
Reaction(KEGG)
R11721 R11722
Substrate
2-dehydro-L-erythronate [CPD:C21618];
2-dehydro-D-erythronate [CPD:C21617]
Product
3-dehydro-L-erythronate [CPD:C21612];
3-dehydro-D-erythronate [CPD:C03064]
Comment
The enzyme, characterized from bacteria, is involved in D-erythronate and L-threonate catabolism.
History
EC 5.3.1.35 created 2017
Orthology
K22131  2-dehydrotetronate isomerase
Genes
ECO: b2739(ygbM)
ECJ: JW2709(ygbM)
ECD: ECDH10B_2907(ygbM)
EBW: BWG_2475(ygbM)
ECOK: ECMDS42_2244(ygbM)
EOI: ECO111_3459(ygbM)
EOJ: ECO26_3804(ygbM)
EOH: ECO103_3277(ygbM)
ESL: O3K_05855
ESO: O3O_19790
ESM: O3M_05900
ECK: EC55989_3006(ygbM)
ECG: E2348C_3005(ygbM)
ELH: ETEC_2930
ECP: ECP_2717
ENA: ECNA114_2775(ygbM)
ECOS: EC958_3007(ygbM)
ECV: APECO1_3785(ygbM)
ECY: ECSE_2987
ECR: ECIAI1_2834(ygbM)
ECQ: ECED1_3192(ygbM)
EBR: ECB_02589(ygbM)
EBL: ECD_02589(ygbM)
EBE: B21_02554(ygbM)
EBD: ECBD_0985
ECI: UTI89_C3105(ygbM)
ECZ: ECS88_3006(ygbM)
ECC: c3300(ygbM)
ESE: ECSF_2533
EAB: ECABU_c30120(ygbM)
EDJ: ECDH1ME8569_2649(ygbM)
ELW: ECW_m2941(ygbM)
ELL: WFL_14360
ELC: i14_3029(ygbM)
ELD: i02_3029(ygbM)
ELP: P12B_c2842(ygbM)
ELF: LF82_3142(ygbM)
ECOI: ECOPMV1_02997(ygbM)
ECOJ: P423_15005
STY: STY3040(hyi)
STT: t2816(hyi)
STM: STM2915(ygbM)
SEO: STM14_3517(ygbM)
SEY: SL1344_2894(hyi)
SEJ: STMUK_2904(ygbM)
SEB: STM474_3055(ygbM)
SEF: UMN798_3163(hyi)
SENR: STMDT2_28151(hyi)
SEND: DT104_29131(hyi)
SENI: CY43_15215
SPT: SPA2772
SEK: SSPA2584
SEI: SPC_2957
SEC: SCH_2845(ygbM)
SHB: SU5_03394
SENS: Q786_14045
SEG: SG2818(ygbM)
SEL: SPUL_2913(ygbM)
SEGA: SPUCDC_2899(ygbM)
SET: SEN2754(ygbM)
SENA: AU38_13990
SENO: AU37_14000
SENV: AU39_14000
SENQ: AU40_15755
SENL: IY59_14595
SENE: IA1_13965
SBG: SBG_2529(hyi)
SBZ: A464_2932
SSN: SSON_2887(ygbM)
SBO: SBO_2781(ygbM)
KPN: KPN_01602(ygbM)
KPU: KP1_2629(ygbM)
KPP: A79E_2634
KPR: KPR_2487
KPJ: N559_2720
KPX: PMK1_03923(ygbM)
KPNU: LI86_13550
KVA: Kvar_2741
EAE: EAE_18675
EAR: CCG30155
CAMA: F384_03225
YPE: YPO1238
YPK: y2949
YPH: YPC_2966
YPA: YPA_0952
YPN: YPN_2740
YPM: YP_0903(hfi1)
YPZ: YPZ3_1138
YPD: YPD4_1099
YPX: YPD8_1048
YPW: CH59_606
YPJ: CH55_1311
YPV: BZ15_2317
YPL: CH46_3892
YPS: YPTB1273
YPO: BZ17_1251
YPY: YPK_2823
YPB: YPTS_1363
YPQ: DJ40_961
YPU: BZ21_545
YPR: BZ20_711
YPC: BZ23_877
YPF: BZ19_678
YEN: YE2501
YEY: Y11_06801
YEW: CH47_1848
YET: CH48_4000
YFR: AW19_949
YIN: CH53_3696
YKR: CH54_714
SMAR: SM39_0931
SPE: Spro_1489
SRL: SOD_c13810(ygbM)
SPLY: Q5A_007505(ygbM_1)
SMAF: D781_1418
SERF: L085_21080
SFJ: SAMEA4384070_1538(ygbM)
SOF: NCTC11214_05431(ygbM_2)
ECA: ECA4330
PATR: EV46_21560
PATO: GZ59_44260
PCT: PC1_0115
PEC: W5S_0111
EAM: EAMY_1102(ygbM)
EAY: EAM_1109
ETA: ETA_23650(ygbM)
EPY: EpC_25000(ygbM)
EPR: EPYR_02706(ygbM)
EBI: EbC_42970
ERJ: EJP617_22280(ygbM)
EGE: EM595_2342(ygbM)
PAM: PANA_2456(ygbM)
PLF: PANA5342_1630(ygbM)
PAJ: PAJ_1753(ygbM)
PVA: Pvag_1939(ygbM)
PSTW: DSJ_15805
PAY: PAU_02016(gclR)
XDO: XDD1_3208
PSI: S70_07790
PSX: DR96_1614(hyi)
PRG: RB151_005690(ygbM)
PHEI: NCTC12003_00572(ygbM)
PRJ: NCTC6933_00626(ygbM)
PVC: G3341_02560(hyi)
ETR: ETAE_1925
ETD: ETAF_1737
LRI: NCTC12151_03003(ygbM)
HIN: HI_1013
HIU: HIB_11520
HIZ: R2866_1372(ygbM)
HIA: H733_1427
HAP: HAPS_1868(tsa)
HPAZ: K756_11865
HPAS: JL26_10385
HPAK: JT17_07605
HSO: HS_0015
HSM: HSM_1906
PMU: PM1363
PMV: PMCN06_1613(gip)
PMP: Pmu_15940
PMUL: DR93_196
MSU: MS1978(hfi)
MHT: D648_1720
MHAT: B824_24890
MHX: MHH_c07100(hfi)
MHAE: F382_07285
MHAM: J450_07745
MHAO: J451_08680
MHAL: N220_00800
MHAQ: WC39_13265
MHAY: VK67_13270
MVR: X781_1090
ASU: Asuc_0120
AAT: D11S_0031
AAN: D7S_01611
AACN: AANUM_1068
AVT: NCTC3438_00336(ygbM)
RPNE: NCTC8284_00712(ygbM)
PAET: NCTC13378_01828(ygbM)
VAG: N646_4712
VSA: VSAL_II0211(hyi)
PAE: PA0550
PAEV: N297_562
PAEI: N296_562
PAU: PA14_07150(hyi)
PNC: NCGM2_5644(hyi)
PAEB: NCGM1900_0563(hyi)
PAEP: PA1S_02780
PAEM: U769_02810
PAEL: T223_02785
PAEG: AI22_01120
PAEC: M802_561
PAEO: M801_562
PPT: PPS_4315
PPUH: B479_21700
PPUD: DW66_4704
PMON: X969_21245
PMOT: X970_20880
PSB: Psyr_0462
PSYR: N018_02220
PFL: PFL_3342(hyi_2)
PPRO: PPC_3366(gip)
PFS: PFLU_2356
PSES: PSCI_2107
PSEM: TO66_13355
PSOS: POS17_2724(gip)
PTN: PTRA_a2908(gip)
FBL: Fbal_1237
GAI: IMCC3135_12970(ygbM)
CSA: Csal_3181
HAM: HALO0634
HAF: C8233_00740(hyi)
HAXI: HAALTHF_14870n(hyi)
AHA: AHA_1058
AMED: B224_4228
ACAV: VI35_16045
CHJ: NCTC10426_00302(ygbM)
SALN: SALB1_2044
PSE: NH8B_1334
RSO: RSc0020
RSC: RCFBP_21426(hyi)
RSL: RPSI07_3360(hyi)
RSM: CMR15_30891(hyi)
RSE: F504_22
RSY: RSUY_00240(ygbM)
RPI: Rpic_3736
REH: H16_A1558(hyi1)
RME: Rmet_1839(hyi1)
CGD: CR3_2192
BMA: BMAA0573(hyi)
BML: BMA10229_0894(hyi)
BMN: BMA10247_A1861(hyi)
BMAI: DM57_12655
BMAF: DM51_4294
BMAZ: BM44_4839
BMAB: BM45_4894
BPS: BPSS1419(hyi)
BPM: BURPS1710b_A0442(hyi)
BPL: BURPS1106A_A1924(hyi)
BPSE: BDL_4726
BPSM: BBQ_4729
BPSU: BBN_4864
BPSD: BBX_3889
BPK: BBK_4028
BPSH: DR55_3856
BPSA: BBU_4619
BPSO: X996_3644
BUT: X994_5699
BTQ: BTQ_4268
BTJ: BTJ_5306
BTZ: BTL_3768
BTD: BTI_3911
BTV: BTHA_4115
BTHE: BTN_3890
BTHM: BTRA_3765
BTHA: DR62_3932
BTHL: BG87_3724
BOK: DM82_5575
BOC: BG90_5035
BVE: AK36_3298
BCN: Bcen_3208
BCJ: BCAM2399(hyi)
BCEN: DM39_5448
BCEW: DM40_3063
BCEO: I35_6295(hyi)
BAM: Bamb_4554
BMJ: BMULJ_05021(gip)
BMU: Bmul_3496
BMK: DM80_4887
BMUL: NP80_5039
BCT: GEM_3294
BCED: DM42_5589
BDL: AK34_3419
BCON: NL30_00445
BUB: BW23_3611
BLAT: WK25_27890
BTEI: WS51_08960
BSEM: WJ12_31930
BPSL: WS57_02130
BMEC: WJ16_30455
BSTG: WT74_30840
BGU: KS03_5430
BGO: BM43_4276
BUK: MYA_3086
BUL: BW21_5905
BXE: Bxe_B2169
BXB: DR64_4498
BPH: Bphy_4427
BFN: OI25_6552
PPNO: DA70_17090
PPNM: LV28_13660
PPUL: RO07_07600
PSPU: NA29_03480
PAPI: SG18_08040
PLG: NCTC10937_05026(hyi)
LMIR: NCTC12852_02442(ygbM)
CABA: SBC2_17840(otnI_1) SBC2_68750(otnI_2)
BPA: BPP1378
BPT: Bpet3351
BAV: BAV1375(hyi)
BHO: D560_2518
BHM: D558_2498
BHZ: ACR54_03054(ygbM)
BTRM: SAMEA390648703825(hyi)
AXY: AXYL_05981(hyi1) AXYL_05996(hyi2)
AMIM: MIM_c39380
AFQ: AFA_17315
ODI: ODI_R0405
RFR: Rfer_0443
POL: Bpro_4876
PNA: Pnap_4098
AJS: Ajs_1815
AAA: Acav_1070
ACRA: BSY15_1341
VEI: Veis_2462
DAC: Daci_2809
RTA: Rta_37980(hyi)
LIM: L103DPR2_00244(hyi)
LIH: L63ED372_02636(hyi)
HYB: Q5W_08085
CFU: CFU_3496(hyi2)
CARE: LT85_4014
NOK: FAY22_16165(hyi)
RGE: RGE_14720(hyi)
OTR: OTERR_22880(hfi)
GEO: Geob_3232
SME: SM_b20669
SMER: DU99_26670
SMD: Smed_4320
ARA: Arad_9440
RLG: Rleg_5011
SHZ: shn_26820
KAI: K32_22600
BME: BMEII1092
BMEL: DK63_2166
BMEE: DK62_2110
BMF: BAB2_0144
BABO: DK55_2141
BABR: DO74_2304
BABT: DK49_2251
BABB: DK48_2551
BABU: DK53_2992
BABS: DK51_2480
BABC: DO78_3165
BMS: BRA0147
BSZ: DK67_2171
BOV: BOV_A0132
BCAR: DK60_3026
BCAS: DA85_11210
BMR: BMI_II145
BPP: BPI_II145
BPV: DK65_2323
BJA: blr2929(blr2929)
BRA: BRADO2552
BBT: BBta_2898
BRS: S23_50860
AOL: S58_50610
BRAD: BF49_1762
BARH: WN72_16060
BVZ: BRAD3257_5772(ygbM)
RPA: RPA1753
RPB: RPB_3611
RPD: RPD_1855
RPE: RPE_1699
RPT: Rpal_1953
VGO: GJW-30_1_03230(ygbM)
XAU: Xaut_1026
AZC: AZC_2776
MET: M446_2625
MNO: Mnod_4653
MOR: MOC_1355
MAQU: Maq22A_c12800(hfi)
BID: Bind_2086
MSL: Msil_2268
PLEO: OHA_1_03740(hyi_2)
MMED: Mame_00481(ygbM)
HDI: HDIA_0914(hyi)
SIL: SPO2563
RUT: FIU92_15665(ygbM)
RCP: RCAP_rcc00592(hyi)
DSH: Dshi_1554
KVL: KVU_1235
KVU: EIO_1770
KRO: BVG79_01481(hyi)
PGA: PGA1_c31800(ygbM)
PGL: PGA2_c00900(ygbM)
PGD: Gal_00068
PHP: PhaeoP97_00102(ygbM)
PPIC: PhaeoP14_00068(ygbM)
OTM: OSB_27310(hyi)
LAQU: R2C4_19345
MALG: MALG_01999
RSU: NHU_01480
RHC: RGUI_4079
RMM: ROSMUCSMR3_03168(ygbM)
RID: RIdsm_01849(hyi)
ROH: FIU89_19960(ygbM)
AHT: ANTHELSMS3_04461(ygbM)
MARU: FIU81_13290(ygbM2)
ROT: FIV09_17110(hyi2)
MALU: KU6B_45030(hyi)
PAMO: BAR1_16000
PALW: PSAL_029590(otnI)
SWI: Swit_3267
SPHD: HY78_09220
SPKC: KC8_16510
SECH: B18_05115
ACR: Acry_2430
AMV: ACMV_27480(hyi)
SHUM: STHU_25130(hyi)
SVC: STVA_30550(hyi)
AZL: AZL_a08390(gip)
ALI: AZOLI_p20558(hyi2)
SKT: IGS68_07390(hyi)
RRU: Rru_A2503
RRF: F11_12860
TMO: TMO_1579
TXI: TH3_06960
MAGQ: MGMAQ_2612(hyi)
CPF: CPF_0983
MALV: MALV_49000
CGB: cg2716(hyi)
CGU: WA5_2384(Hyi)
CGT: cgR_2382
CGM: cgp_2716(hyi)
CGJ: AR0_11870
CSUR: N24_2545
SMAL: SMALA_0043
AHEL: Q31a_35850(hyi_1)
TTF: THTE_0812
PLH: VT85_11325(hyi_1)
ULI: ETAA1_57400(hyi)
SRM: SRM_02749
 » show all
Reference
1  [PMID:27402745]
  Authors
Zhang X, Carter MS, Vetting MW, San Francisco B, Zhao S, Al-Obaidi NF, Solbiati JO, Thiaville JJ, de Crecy-Lagard V, Jacobson MP, Almo SC, Gerlt JA
  Title
Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars.
  Journal
Proc Natl Acad Sci U S A 113:E4161-9 (2016)
DOI:10.1073/pnas.1605546113
  Sequence
[reh:H16_A1558]
Other DBs
ExplorEnz - The Enzyme Database: 5.3.1.35
IUBMB Enzyme Nomenclature: 5.3.1.35
ExPASy - ENZYME nomenclature database: 5.3.1.35
BRENDA, the Enzyme Database: 5.3.1.35

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