KEGG   ENZYME: 5.3.3.5
Entry
EC 5.3.3.5                  Enzyme                                 
Name
cholestenol Delta-isomerase
Class
Isomerases;
Intramolecular oxidoreductases;
Transposing C=C bonds
Sysname
Delta7-cholestenol Delta7-Delta8-isomerase
Reaction(IUBMB)
5alpha-cholest-7-en-3beta-ol = 5alpha-cholest-8-en-3beta-ol [RN:R03353]
Reaction(KEGG)
R03353;
(other) R04671 R04804 R07484
Substrate
5alpha-cholest-7-en-3beta-ol [CPD:C01189]
Product
5alpha-cholest-8-en-3beta-ol [CPD:C03845]
History
EC 5.3.3.5 created 1972
Pathway
ec00100  Steroid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K01824  cholestenol Delta-isomerase
Genes
HSA10682(EBP)
PTR107971057(EBP)
PPS100990984(EBP)
GGO109024659(EBP)
PON100172558(EBP)
NLE100596932(EBP)
MCC714315(EBP)
MCF102125224
MTHB126933713 126945617 126963254
CSAB103231927(EBP)
CATY105590476(EBP)
PANU101005849(EBP)
TGE112615053(EBP)
RRO104660666(EBP)
RBB108517459(EBP)
TFN117077373(EBP)
PTEH111531798(EBP)
CJC100398463(EBP)
SBQ101050388(EBP)
CSYR103250481(EBP)
MMUR105856392(EBP)
LCAT123628354
OGA100954660(EBP)
MMU13595(Ebp)
MCAL110286712(Ebp)
MPAH110313992(Ebp)
RNO117278(Ebp)
MCOC116068857(Ebp)
MUN110543210(Ebp)
CGE100765639(Ebp)
MAUA101824914
PLEU114701311
MORG121442536
MFOT126512887
AAMP119805272
NGI103741636(Ebp)
HGL101701732(Ebp)
CPOC100135518(Ebp)
CCAN109698115(Ebp)
DORD105992298 105997814(Ebp)
DSP122098778
NCAR124971962
OCU100343087(EBP)
OPI101532215
TUP102474512(EBP)
CFA100685679 609430(EBP)
CLUD112657812 112673146
VVP112907225(EBP)
VLG121482294 121493673
AML100473435(EBP)
UMR103663596(EBP)
UAH113265916(EBP)
UAR123787598
ELK111150519
LLV125091656
MPUF101671225(EBP)
ORO101378326(EBP)
EJU114216853(EBP)
ZCA113931473
MLX118010004(EBP)
NSU110570929
FCA101094572(EBP)
PYU121026163
PBG122477962
LRUF124509504
PTG102967500(EBP)
PPAD109248063(EBP)
AJU106989469(EBP)
HHV120221015
BTA515569(EBP)
BOM102273554(EBP)
BIU109555438(EBP)
BBUB102394825 123333811
CHX102177226(EBP)
OAS101102976 101112029(EBP)
ODA120882087
CCAD122434507
SSC100312968(EBP)
CFR102519508(EBP)
CBAI105079388(EBP)
CDK105103312(EBP)
VPC102532879(EBP)
BACU103004802(EBP)
LVE103072192(EBP)
OOR101269262(EBP)
DLE111169493(EBP)
PCAD102990303(EBP)
PSIU116747923(EBP)
ECB100051672(EBP)
EPZ103544680(EBP)
EAI106827435
MYB102241443(EBP)
MYD102762613(EBP)
MMYO118653963
MLF102423304(EBP)
MNA107541410(EBP)
PKL118731784
HAI109374804(EBP)
DRO112322433(EBP)
SHON118998312
AJM119059933
PDIC114505394
PHAS123832732
MMF118635884
RFQ117021656(EBP)
PALE102890445(EBP)
PGIG120587100
PVP105310017(EBP)
RAY107515036(EBP)
MJV108404731(EBP)
TOD119246178
SARA101553087(EBP)
LAV100654061(EBP) 100670269
TMU101350389
DNM101416173(EBP)
MDO100018802(EBP)
GAS123254633
SHR100933447(EBP)
PCW110201004(EBP)
OAA100082141
GGA100857622
PCOC116240906(EBP)
MGP104916040
CJO107307202(EBP)
NMEL110391534(EBP)
OTC121342048
PRUF121355810
PHI102101811
ASN102379953(EBP)
AMJ102565058(EBP) 106739994
PSS102461665(EBP)
CMY102935780
CPIC101949826
TST117889113(EBP)
CABI116818888(EBP)
MRV120388555
ACS100564809(ebp)
PVT110081200(EBP)
SUND121924117
PBI103051122(EBP)
PMUR107291933 107292005 107300059
CTIG120306625 120306626 120306627 120306634 120309645
PGUT117656447
VKO123024035
PMUA114587829(EBP) 114587880
ZVI118075199(EBP)
GJA107120738(EBP)
STOW125430121
XLA108700304(ebp.S) 380161(ebp.L)
XTR100216262(ebp)
NPR108789213(EBP)
RTEM120913902
BBUF121009445
BGAR122919324
DRE436600(ebp)
SRX107712744
SANH107657016 107672060
SGH107580309(ebp)
CCAR109110935 109111057
CAUA113069130(ebp)
PPRM120462932
MAMB125260525
IPU108275532
PHYP113530387(ebp)
SMEO124399069
TFD113658103
AMEX103033067(ebp)
TRU101071497(ebp)
LCO109140513(ebp)
NCC104941566(ebp)
CGOB115010782(ebp)
ELY117258634(ebp)
EFO125892405
PLEP121947381
SLUC116058568
ECRA117947655(ebp)
ESP116692453(ebp)
PFLV114558356(ebp)
GAT120829772
PPUG119223156
MSAM119919289
CUD121518097
ALAT119022100
MZE101477298(ebp)
ONL100693619(ebp)
OAU116330810
OLA101155430(ebp)
OML112159202
XMA102229693(ebp)
XCO114152834(ebp)
XHE116722084(ebp)
PRET103467404(ebp)
PFOR103149608(ebp)
PLAI106946642(ebp)
PMEI106925236(ebp)
GAF122828112
CVG107091634(ebp)
CTUL119785027
GMU124865778
NFU107390937(ebp)
KMR108235218
ALIM106524384(ebp)
NWH119416940
AOCE111580686(ebp)
MCEP125011872
CSEM103384544(ebp)
POV109648064(ebp)
SSEN122777308
HHIP117764025(ebp)
HSP118111509
LCF108889448
SDU111218949(ebp)
SLAL111669013(ebp)
XGL120803509
HCQ109528242(ebp)
BPEC110164888(ebp)
MALB109969717(ebp)
BSPL114858860
SASA106573007 106591920
STRU115165230(ebp)
OTW112237066
OMY110532880
OGO124032445
ONE115120175(ebp)
SALP112072434(ebp)
SNH120038670
CCLU121563300
ELS105008755
SFM108918513(ebp)
PKI111857065(ebp)
AANG118210773(ebp)
LOC102686313(ebp)
PSPA121307802
ARUT117401621 117404389
LCM102365689(EBP)
RTP109925911(ebp)
BFO118415339
BBEL109487916
SPU589723
APLC110974080 110974081 110974117
SKO100371931
LGILOTGIDRAFT_188540
PCAN112571534
BGT106072875
GAE121369152
HRF124136345 124136346
HRJ124287833
CRG105317278
MMER123528647
NVE5508329
EPA110231397
ADF107353731
AMIL114956896
PDAM113667741
SPIS111325424
DGT114519379
TADTRIADDRAFT_23897
AQU100636492
ATHAT1G20050(HYD1)
ALY9326429
CRB17900773
CSAT104740701 104756354 104776121
EUSEUTSA_v10008732mg
BRP103829457 103872807
BNA106358260 106389651 106410531 106410538
BOE106306597
RSZ108813130
THJ104807222
CIT102606772 102607060 102618211 102624206
CICCICLE_v10002435mg CICLE_v10006027mg CICLE_v10029254mg CICLE_v10029256mg
PVY116110675
MINC123193727
TCC18612950
GRA105798026
GHI107888454 107888521
GAB108455726
DZI111300606
EGR104422216
GMX100783250 100783787 100815125
GSJ114367284 114367307 114381840 114424973
PVUPHAVU_004G160000g
VRA106764066
VAR108344937
VUN114180987
CCAJ109818254
APRC113867878
MTR25496873
CAM101505961
LJALj0g3v0359339.1(Lj0g3v0359339.1)
ADU107471355
AIP107623149
AHF112716530 112782579
LANG109358908
FVE101305754
RCN112198039
PPER18793484
PMUM103322172
PAVI110748050 110766031
PDUL117638815
MDM103452509
PXB103944742 103950376
ZJU107431850
MNT21391344
CSV101206897
CMO103494647
BHJ120072667
MCHA111024900
CMAX111479580
CMOS111457598
CPEP111789846
RCU8285718
JCU105634610
HBR110638791 110667163
MESC110627430
POP7496516
PEU105110856 105123119
PALZ118054397
JRE109006700
QSU111994997 112009666
QLO115982201
TWL120007031
VVI100263963
VRI117915799
SLY101259646
SPEN107023447
SOT102577874(SI1)
SSTN125873275
CANN107875372
NTA107768926 107810836
NSY104234035
NTO104085771
NAU109218089
INI109182765
ITR116024945
SIND105163782
OEU111403674 111403676
EGT105954459
SSPL121760196 121763490
HAN110937955
ECAD122590968
LSV111889257 111910529
CCAV112507100
DCR108220488
CSIN114300193 114303880 114313622
BVG104901952 104901953 104901954 104901956 104901957 104901962
SOE110776270 110800116
CQI110708004 110725577 110725579
NNU104591910 104592693
MING122071631
TSS122667998
PSOM113280157 113290034
NCOL116259015
OSA4326449
DOSAOs01t0103600-01(Os01g0103600)
OBR102718878 102721565
BDI100828892
ATS109759243 109759246 109776763
TDC119267007 119274819 119298749 119307201
TAES123060184 123068681 123077191 123087851 123106275 123106276 123115513 123115514 123115515 123115525 123124072 123124073 123164430
TUA125542552 125542686
SBI8072372 8085050 8085052 8085054
ZMA103649921 732747
SITA101764347 101767473 101784609
SVS117857554 117857721 117858677
PVIR120676528 120676529 120706290 120706291 120706299
PHAI112893901 112894636 112895106
PDA103698789 103713270
EGU105037247 105050974
MUS103987096
DCT110096374
PEQ110025271
AOF109823553 109830892
ATR18429032
SMOSELMODRAFT_449563(HYD1A-1) SELMODRAFT_449597(HYD1B-1) SELMODRAFT_449598(HYD1B-2) SELMODRAFT_449599(HYD1A-2)
PPP112286824
CRECHLRE_12g557900v5
MNGMNEG_8628
CSLCOCSUDRAFT_13584
CVRCHLNCDRAFT_34496
APROF751_3634
NCRNCU00346
NTENEUTE1DRAFT42660(NEUTE1DRAFT_42660)
SMPSMAC_06475
TTTTHITE_2146203
MTMMYCTH_2118284 MYCTH_56173
CTHRCTHT_0027470
MGRMGG_04574 MGG_14756
PPEIPpBr36_00283 PpBr36_00536
TMNUCRPA7_8122
SSCKSPSK_04462
FGRFGSG_12748 FGSG_13888
FPUFPSE_03517 FPSE_06043 FPSE_06044
FVRFVEG_07039 FVEG_11622 FVEG_17062
FOXFOXG_09408 FOXG_12873
NHENECHADRAFT_68940
TRETRIREDRAFT_123008 TRIREDRAFT_68843
TRRM419DRAFT_133622 M419DRAFT_25753
MAWMAC_02508
MAJMAA_03436 MAA_08625
CMTCCM_07516 CCM_07586 CCM_08895
PLJVFPFJ_01224 VFPFJ_02065 VFPFJ_11136
VALVDBG_02909 VDBG_06803
VDAVDAG_03817 VDAG_05867
CFJCFIO01_03151 CFIO01_03870
CHIGCH63R_02266 CH63R_05161
SAPOSAPIO_CDS5322 SAPIO_CDS7724 SAPIO_CDS9047
PFYPFICI_07996
SSLSS1G_06945 SS1G_07733
BFUBCIN_04g02260(Bcebp4) BCIN_10g03150(Bcebp2) BCIN_15g01490
MBEMBM_00983 MBM_06609
PSCOLY89DRAFT_535811 LY89DRAFT_688090 LY89DRAFT_703638
GLZGLAREA_01999
ANIAN0851.2 AN7211.2
AFMAFUA_1G15100 AFUA_3G00810
ACTACLA_020260
NFINFIA_001440 NFIA_010320
AORAO090005001216 AO090026000084
ANGANI_1_3232014(An01g13260)
AFVAFLA_004035 AFLA_006222 AFLA_010083
ALUCAKAW2_10302A AKAW2_70966S
ACHEACHE_30670S ACHE_70181S
APUUAPUU_21312A APUU_50962A
PCSPc06g00810 Pc21g21520
PDPPDIP_05510
TMFPMAA_073830
TRGTRUGW13939_09076
CIMCIMG_03226
CPWCPC735_009450
UREUREG_07084
PBLPAAG_02126
PBNPADG_00767
ABEARB_01849
TVETRV_04622
AJEHCAG_06820
BGHBDBG_03094
PNOSNOG_02221
PTEPTT_19437
BZECOCCADRAFT_29360
BSCCOCSADRAFT_103550
BORCOCMIDRAFT_109256
AALTCC77DRAFT_927132
ZTRMYCGRDRAFT_36488
PFJMYCFIDRAFT_186161
FFUCLAFUR5_03219
NPAUCRNP2_8512
DDIDDB_G0269414(ebp)
DPPDICPUDRAFT_91317
DFADFA_02477(ebp)
ACANACA1_282370
TETTTHERM_00600440
PTMGSPATT00001804001 GSPATT00005258001 GSPATT00038592001
SPARSPRG_13330
MRMA7982_02974
SRKFGW37_00265
 » show all
Reference
1  [PMID:5810070]
  Authors
Wilton DC, Rahimtula AD, Akhtar M.
  Title
The reversibility of the delta8-cholestenol-delta7-cholestenol isomerase reaction in cholesterol biosynthesis.
  Journal
Biochem J 114:71-3 (1969)
DOI:10.1042/bj1140071
Other DBs
ExplorEnz - The Enzyme Database: 5.3.3.5
IUBMB Enzyme Nomenclature: 5.3.3.5
ExPASy - ENZYME nomenclature database: 5.3.3.5
BRENDA, the Enzyme Database: 5.3.3.5
CAS: 52410-46-5

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