KEGG   ENZYME: 5.5.1.30
Entry
EC 5.5.1.30                 Enzyme                                 

Name
labda-7,13-dienyl diphosphate synthase;
SCLAV_p0490
Class
Isomerases;
Intramolecular lyases;
Intramolecular lyases (only sub-subclass identified to date)
Sysname
(13E)-labda-7,13-dien-15-yl-diphosphate lyase (ring-opening)
Reaction(IUBMB)
geranylgeranyl diphosphate = (13E)-labda-7,13-dien-15-yl diphosphate [RN:R11871]
Reaction(KEGG)
R11871
Substrate
geranylgeranyl diphosphate [CPD:C00353]
Product
(13E)-labda-7,13-dien-15-yl diphosphate [CPD:C21727]
Comment
Isolated from the bacterium Streptomyces clavuligerus.
History
EC 5.5.1.30 created 2017
Orthology
K03463  labda-7,13-dienyl diphosphate synthase
Reference
1  [PMID:26814669]
  Authors
Yamada Y, Komatsu M, Ikeda H
  Title
Chemical diversity of labdane-type bicyclic diterpene biosynthesis in Actinomycetales microorganisms.
  Journal
J Antibiot (Tokyo) 69:515-23 (2016)
DOI:10.1038/ja.2015.147
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 5.5.1.30
IUBMB Enzyme Nomenclature: 5.5.1.30
ExPASy - ENZYME nomenclature database: 5.5.1.30
BRENDA, the Enzyme Database: 5.5.1.30

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