KEGG   ENZYME: 5.99.1.4
Entry
EC 5.99.1.4                 Enzyme                                 
Name
2-hydroxychromene-2-carboxylate isomerase;
HCCA isomerase;
2HC2CA isomerase;
2-hydroxychromene-2-carboxylic acid isomerase
Class
Isomerases;
Other isomerases;
Sole sub-subclass for isomerases that do not belong in the other subclasses
Sysname
2-hydroxy-2H-chromene-2-carboxylate---(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate isomerase
Reaction(IUBMB)
2-hydroxy-2H-chromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate [RN:R05137]
Reaction(KEGG)
R05137
Substrate
2-hydroxy-2H-chromene-2-carboxylate [CPD:C06204]
Product
(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate [CPD:C06203]
Comment
This enzyme is involved in naphthalene degradation.
History
EC 5.99.1.4 created 2010
Pathway
ec00626  Naphthalene degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K14584  2-hydroxychromene-2-carboxylate isomerase
Genes
PAEUBN889_06506
PPIND062(nahD)
PFKPFAS1_28645
PSCA458_06695
PSTUUIB01_22655
ALTambt_17880
CYQQ91_2218(dsbA2)
CZACYCME_2536
CYYCPC19_01710
FCEJN531_005660
GBIPG2T_11410
RPJN234_23845
RMNTK49_07985
BMKDM80_1450(doxJ)
BUQAC233_10855 AC233_11015 AC233_11145
BFNOI25_3056(nahD)
PARBCJU94_38630
PUTPT7_1103
PIGEGT29_20110
PNAPnap_2478
ACIDCBP33_05325
ACIPCBP36_05775
ACINCBP34_05160
ACISCBP35_13170
DELDelCs14_1745
MASWAM586_27545
RBUPG1C_04270
PLAPlav_3649
RRGJ3P73_35260
MAADAZF01_18320
CIDP73_0352
CONTQ29_19105
PGVSL003B_4081 SL003B_4106
NARSaro_3869
NPPPP1Y_AT15569 PP1Y_AT31717
NPNJI59_21735 JI59_21885 JI59_24555
NOGGKE62_05170
SBARH5V43_22255
SPHYCHN51_06890
SANDH3309_09115
CNAAB433_10405 AB433_18205
ERYCP97_14145
NCHA0U93_15775
HTQFRZ44_46320
HADHFRZ61_44250
 » show all
Reference
1  [PMID:9722670]
  Authors
Ohmoto T, Kinoshita T, Moriyoshi K, Sakai K, Hamada N, Ohe T
  Title
Purification and some properties of 2-hydroxychromene-2-carboxylate isomerase from naphthalenesulfonate-assimilating Pseudomonas sp. TA-2.
  Journal
J Biochem 124:591-7 (1998)
DOI:10.1093/oxfordjournals.jbchem.a022152
Reference
2  [PMID:16804169]
  Authors
Keck A, Conradt D, Mahler A, Stolz A, Mattes R, Klein J
  Title
Identification and functional analysis of the genes for naphthalenesulfonate catabolism by Sphingomonas xenophaga BN6.
  Journal
Microbiology 152:1929-40 (2006)
DOI:10.1099/mic.0.28783-0
  Sequence
Reference
3  [PMID:8002605]
  Authors
Eaton RW
  Title
Organization and evolution of naphthalene catabolic pathways: sequence of the DNA encoding 2-hydroxychromene-2-carboxylate isomerase and trans-o-hydroxybenzylidenepyruvate hydratase-aldolase from the NAH7 plasmid.
  Journal
J Bacteriol 176:7757-62 (1994)
DOI:10.1128/JB.176.24.7757-7762.1994
  Sequence
Reference
4  [PMID:17508726]
  Authors
Thompson LC, Ladner JE, Codreanu SG, Harp J, Gilliland GL, Armstrong RN
  Title
2-Hydroxychromene-2-carboxylic acid isomerase: a kappa class glutathione transferase from Pseudomonas putida.
  Journal
Biochemistry 46:6710-22 (2007)
DOI:10.1021/bi700356u
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 5.99.1.4
IUBMB Enzyme Nomenclature: 5.99.1.4
ExPASy - ENZYME nomenclature database: 5.99.1.4
UM-BBD (Biocatalysis/Biodegradation Database): 5.99.1.4
BRENDA, the Enzyme Database: 5.99.1.4

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