KEGG   ENZYME: 6.2.1.76
Entry
EC 6.2.1.76                 Enzyme                                 
Name
malonate---CoA ligase;
ACSF3 (gene name);
AAE13 (gene name);
malonyl-CoA synthetase
Class
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases
Sysname
malonate:CoA ligase (AMP-forming)
Reaction(IUBMB)
ATP + malonate + CoA = AMP + diphosphate + malonyl-CoA [RN:R12300]
Reaction(KEGG)
R12300
Substrate
ATP [CPD:C00002];
malonate [CPD:C00383];
CoA [CPD:C00010]
Product
AMP [CPD:C00020];
diphosphate [CPD:C00013];
malonyl-CoA [CPD:C00083]
Comment
The enzyme, found in mitochondria, detoxifies malonate, which is a potent inhibitor of mitochondrial respiration, and provides malonyl-CoA to the mitochondrial fatty acid biosynthesis pathway.
History
EC 6.2.1.76 created 2022
Pathway
ec00061  Fatty acid biosynthesis
ec01100  Metabolic pathways
Orthology
K18660  malonyl-CoA/methylmalonyl-CoA synthetase
K18661  malonyl-CoA/methylmalonyl-CoA synthetase
Genes
HSA197322(ACSF3)
PTR454311(ACSF3)
PPS100993031(ACSF3)
GGO101148664(ACSF3)
PON100459097(ACSF3)
NLE100584583(ACSF3)
MCC106995123(ACSF3)
MCF102124170(ACSF3)
MTHB126944311
CSAB103233469(ACSF3)
CATY105587971(ACSF3)
PANU101011656(ACSF3)
TGE112614474(ACSF3)
RRO104655975(ACSF3)
RBB108520197(ACSF3)
TFN117088226(ACSF3)
PTEH111553831(ACSF3)
CJC100389759(ACSF3)
SBQ101045750(ACSF3)
CSYR103255185(ACSF3)
MMUR105855877(ACSF3) 105855961
LCAT123625390(ACSF3)
OGA100960737(ACSF3)
MMU257633(Acsf3)
MCAL110299939(Acsf3)
MPAH110337582(Acsf3)
RNO498962(Acsf3)
MCOC116070344(Acsf3)
MUN110545227(Acsf3)
CGE100764604(Acsf3)
MAUA101825930(Acsf3)
PLEU114700982(Acsf3)
MORG121446712(Acsf3)
MFOT126515517
AAMP119802155(Acsf3)
NGI103739998(Acsf3)
HGL101708737(Acsf3)
CPOC100729577(Acsf3)
CCAN109692748(Acsf3)
DORD106000388(Acsf3)
DSP122127969(Acsf3)
NCAR124967288
OCU100344547
OPI101534220(ACSF3)
TUP102494496(ACSF3)
CFA100683704(ACSF3)
CLUD112646830(ACSF3)
VVP112924630(ACSF3)
VLG121499778(ACSF3)
AML100468387(ACSF3)
UMR103673852(ACSF3)
UAH113252139(ACSF3)
UAR123776597(ACSF3)
ELK111152858
LLV125088730
MPUF101689787(ACSF3)
ORO101380436(ACSF3)
EJU114201587(ACSF3)
ZCA113936602(ACSF3)
MLX118023458(ACSF3)
NSU110594186(ACSF3)
FCA101099921(ACSF3)
PYU121009936(ACSF3)
PBG122494609(ACSF3)
LRUF124511586
PTG102952439(ACSF3)
PPAD109245531(ACSF3)
AJU106973497(ACSF3)
HHV120226893(ACSF3)
BTA509209(ACSF3)
BOM102268238(ACSF3)
BIU109572849(ACSF3)
BBUB102404462(ACSF3)
CHX102169989(ACSF3)
OAS101109383(ACSF3)
ODA120872950(ACSF3)
CCAD122420910(ACSF3)
SSC100739500(ACSF3)
CFR102514930(ACSF3)
CBAI105080886(ACSF3)
CDK105104336(ACSF3)
VPC102532795(ACSF3)
BACU103006350(ACSF3)
LVE103069795(ACSF3)
OOR101272385(ACSF3)
DLE111179387(ACSF3)
PCAD102978174(ACSF3)
PSIU116744159(ACSF3)
ECB100051639(ACSF3)
EPZ103562086(ACSF3)
EAI106828244(ACSF3)
MYB102264099(ACSF3)
MYD102757514(ACSF3)
MMYO118674498(ACSF3)
MLF102430343(ACSF3)
MNA107543506(ACSF3)
PKL118720679(ACSF3)
HAI109389204(ACSF3)
DRO112300687(ACSF3)
SHON118982960(ACSF3)
AJM119047029(ACSF3)
PDIC114488330(ACSF3)
PHAS123806189(ACSF3)
MMF118639433(ACSF3)
RFQ117035240(ACSF3)
PALE102888559(ACSF3)
PGIG120622880(ACSF3)
PVP105299907(ACSF3)
RAY107502352(ACSF3)
MJV108398345(ACSF3)
TOD119248857(ACSF3)
SARA101537950(ACSF3)
LAV100665435(ACSF3)
TMU101348352
MDO100026661(ACSF3)
GAS123236764(ACSF3)
SHR100934834(ACSF3)
PCW110210298(ACSF3)
OAA100080846(ACSF3)
GGA427561(ACSF3)
PCOC116244002(ACSF3)
MGP104913064(ACSF3)
CJO107319518(ACSF3)
NMEL110404322(ACSF3)
APLA101789434(ACSF3)
ACYG106046510(ACSF3)
AFUL116493804(ACSF3)
TGU100226659(ACSF3)
LSR110468775(ACSF3)
SCAN103816762(ACSF3)
PMOA120496217(ACSF3)
OTC121333781(ACSF3)
PRUF121362548(ACSF3)
GFR102043804(ACSF3)
FAB101810484(ACSF3)
PHI102101860(ACSF3)
PMAJ107209950(ACSF3)
CCAE111934399(ACSF3)
CCW104691853(ACSF3)
CBRC103620532(ACSF3)
ETL114068202(ACSF3)
ZAB102065548(ACSF3)
ACHL103809977(ACSF3)
FPG101914803(ACSF3)
FCH102048057(ACSF3)
CLV102096424(ACSF3)
EGZ104127039(ACSF3)
NNI104023568(ACSF3)
PLET104617625(ACSF3)
PCRI104028169(ACSF3)
PCAO104052872(ACSF3)
ACUN113484628(ACSF3)
TALA104357120(ACSF3)
PADL103913407(ACSF3)
AFOR103893828(ACSF3)
ACHC115345347(ACSF3)
HALD104315199
CCRI104163865(ACSF3)
CSTI104550171(ACSF3)
EHS104509138(ACSF3)
CMAC104476845(ACSF3)
MUI104541380(ACSF3)
FGA104081181(ACSF3)
GSTE104259801(ACSF3)
MNB103782423
OHA104337077(ACSF3)
NNT104403733(ACSF3)
DPUB104303774(ACSF3)
PGUU104462159(ACSF3)
ACAR104530325
AVIT104278681(ACSF3)
CVF104290390(ACSF3)
CUCA104061254(ACSF3)
AAM106489294(ACSF3)
AROW112978488(ACSF3)
NPD112949843(ACSF3)
TGT104580329(ACSF3)
DNE112989078(ACSF3)
SCAM104145363(ACSF3)
ASN102375874(ACSF3)
AMJ102560749(ACSF3)
CPOO109310717(ACSF3)
GGN109289385(ACSF3)
PSS102445720(ACSF3)
CMY102929679(ACSF3)
CPIC101938726(ACSF3)
TST117886499(ACSF3)
CABI116815661(ACSF3)
MRV120384448(ACSF3)
ACS100568268(acsf3)
PVT110076304(ACSF3)
SUND121914550(ACSF3)
PBI103058003(ACSF3)
PMUR107283518(ACSF3)
CTIG120302479(ACSF3)
VKO123022232(ACSF3)
PMUA114602140(ACSF3)
ZVI118086900(ACSF3)
GJA107106555(ACSF3)
STOW125443206(ACSF3)
XLA444743(acsf3.S)
XTR100158470(acsf3)
NPR108787714(ACSF3)
RTEM120917967(ACSF3)
BBUF120980761(ACSF3)
BGAR122920838(ACSF3)
DRE562292(acsf3)
SRX107730180(acsf3)
SANH107663040
SGH107561460
CCAR109099865
CAUA113106348(acsf3)
PPRM120492711(acsf3)
MAMB125265845(acsf3)
IPU108259686(acsf3)
PHYP113546722
SMEO124380225(acsf3)
TFD113649677(acsf3)
AMEX103034152(acsf3)
EEE113575703(acsf3)
TRU101063367(acsf3)
TNGGSTEN00017876G001
LCO104922786(acsf3)
NCC104951573(acsf3)
CGOB115006343(acsf3)
ELY117259984(acsf3)
EFO125904216(acsf3)
PLEP121949618(acsf3)
SLUC116067765(acsf3)
ECRA117950759(acsf3)
ESP116690330(acsf3)
PFLV114561012(acsf3)
GAT120810785(acsf3)
PPUG119196609(acsf3)
MSAM119889931(acsf3)
CUD121510882(acsf3)
ALAT119018431(acsf3)
MZE101468267(acsf3)
ONL100707810(acsf3)
OAU116324283(acsf3)
OLA101170745(acsf3)
OML112161017(acsf3)
XMA102230562(acsf3)
XCO114143356(acsf3)
XHE116718898(acsf3)
PRET103462378(acsf3)
PFOR103139337(acsf3)
PLAI106946109(acsf3)
PMEI106928014(acsf3)
GAF122822434(acsf3)
CVG107091333(acsf3)
CTUL119782778(acsf3)
GMU124867547(acsf3)
NFU107381230(acsf3)
KMR108250104(acsf3)
ALIM106513917(acsf3)
NWH119428685(acsf3)
AOCE111588400(acsf3)
MCEP125005483(acsf3)
CSEM103378655(acsf3)
POV109624726(acsf3)
SSEN122772676(acsf3)
HHIP117757849(acsf3)
HSP118112817(acsf3)
LCF108887665
SDU111238435(acsf3)
SLAL111668336(acsf3)
XGL120795235(acsf3)
HCQ109519728(acsf3)
BPEC110173014(acsf3)
MALB109965423(acsf3)
BSPL114851768(acsf3)
SASA106562165(acsf3)
STRU115202980(acsf3)
OTW112249120 112263579(acsf3)
OMY110506418(acsf3) 110526303
OGO124033831 124035813
ONE115113588(acsf3)
SALP111969314 111974773
SNH120024984
CCLU121559458(acsf3)
ELS105017127(acsf3)
SFM108934574(acsf3)
PKI111832951(acsf3)
AANG118215780(acsf3)
LOC102693053(acsf3)
PSPA121326066(acsf3)
ARUT117425030
LCM102359073(ACSF3)
CMK103188085(acsf3)
RTP109922101(acsf3)
BFO118417533
BBEL109480597
CIN100175199
SCLV120325763
SPU579933
APLC110973722
SKO102806707 102808696
DMEDmel_CG18155(CG18155)
DER6551437
DSE6618977
DSIDsimw501_GD16841(Dsim_GD16841)
DYADyak_GE15712
DAN6503827
DSR110183531
DPO6901754 6903086
DPE6588871 6589366 6597648
DMN108163390 108163922 108164940
DWI6637694
DGR6565671
DMODmoj_GI15946
DAZ108620017
DNV115565182
DHE111602856
DVI6636062
CCAT101457408
MDE101893765
SCAC106089642
LCQ111677053
LSQ119600604
ACOZ120959131
AARA120904595
ASTE118503962
AAG5578522
AALB109402281 115257375
CQUCpipJ_CPIJ000791 CpipJ_CPIJ006459
CNS116340216
BCOO119078953
NVI100123908
CSOL105363664
TPRE106651344
MDL103575693
CGLO123267686
FAS105264336
DAM107044863
AGIF122857106
LHT122511144
CCIN107269595
TCA664439
DPA109542551 109545632
SOY115878322 115878746
ATD109595780
CSET123307725
AGB108903910 108917560
LDC111505516
NVL108559274
APLN108741592
PPYR116169511 116171268
OTU111419717
BMOR101739309
MSEX115443005 119190472
DPLKGM_203551 KGM_203552 KGM_203553
BANY112055475
NIQ126777358
PMAC106718666
PPOT106102907
PXU106118453
PRAP111000397
ZCE119837090
HAW110377632
HZE124641511
TNL113494291
SLIU111350763
OFU114357238
PXY105384618 105384619
API100168625
DNX107165065
AGS114121417
RMD113547994
BTAB109042193
CLEC106664913
HHAL106685843
NLU111043993
PHUPhum_PHUM550040
FOC113202116 113204159
TPAL117639069 117642341
ZNE110829175
CSEC111867108
FCD110841952
DPXDAPPUDRAFT_304782 DAPPUDRAFT_304783
DMK116917241 116917243
PVM113810650
PJA122252775
PCHN125042332
HAME121859064
PCLA123767340
PTRU123504645
HAZT108679595
EAF111708016 111708041 111708064
LSM121114532 121117950
PPOI119089971
ISCIscW_ISCW011807 IscW_ISCW014871
DSV119431398 119464687
RSAN119375532 119378299
RMP119176316 119176350
VDE111252504 111252612
VJA111264832 111267693
CSCU111623736 111626442 111626458
PTEP107437889
SDM118184051
HROHELRODRAFT_112159
LGILOTGIDRAFT_179813
PCAN112576533
BGT106062106
GAE121388950
HRF124112498
HRJ124283485
CRG105342284
MYI110449900
PMAX117337548
MMER123550534
OBI106874666
OSN115210163 115212217
LAK106151525
NVE5521216
EPA110241051
ATEN116286866
AMIL114969610
PDAM113673905
SPIS111323410
AQU100638565 105315690
ATHAT3G16170(AAE13)
ALY9321193
CRB17893307
CSAT104745942 104765454 104781031
EUSEUTSA_v10020466mg
BRP103840132 103869849
BNA106348567 106376853 106397262 106452226
BOE106316369 106343566
RSZ108813652 108856547
THJ104817978
CPAP110824700 110825920
CIT102619243
CICCICLE_v10025185mg
PVY116136235
MINC123209928 123218039
TCC18595956
GRA105776753
GHI107897183 107913899
GAB108483454
DZI111278937
EGR104423091
GMX100810130 100813324
GSJ114418008 114422397
PVUPHAVU_010G148300g
VRA106774327
VAR108320665
VUN114167163
CCAJ109808002
APRC113857036
MTR25491371 25491411
CAM101497000 101510623
PSAT127107645 127107646
LJALj3g3v2312070.1(Lj3g3v2312070.1)
ADU107464053
AIP107618487
AHF112709904 112778582
LANG109347001 109347831
FVE101313429
RCN112187693
PPER18782111
PMUM103327893 103327908
PAVI110769490
PDUL117621239
MDM103405442 103421837
PXB103944850
ZJU107405227
MNT21408887
CSV101208501
CMO103493370
BHJ120090959
MCHA111020569
CMAX111494602
CMOS111464352
CPEP111779370
RCU8273830
JCU105635019
HBR110639934
MESC110627022
POP18094769
PEU105113729
PALZ118046205
JRE109000578
QSU111988084 111994248 112019048 112030291 112036030
QLO115991708
TWL119990383 120011548
VVI100258310
VRI117922211
SLY101245036
SPEN107007252
SOT102592845
SSTN125862011
CANN107850422 107861837
NTA107769691 107773712 107785193 107789300 107800203 107812885
NSY104234782 104246019
NTO104090327 104118498
NAU109206524 109225548 109238134
INI109188086 109192466
ITR115997392 116010460
SIND105157654
OEU111366194
EGT105975855
SSPL121795102 121797834
HAN110918791
ECAD122588606
LSV111900808
CCAV112510212
DCR108196830
CSIN114291250
BVG104904717
SOE110801728
CQI110698807 110703394
NNU104595150
MING122077282
TSS122655942
PSOM113303972 113338070
NCOL116245368
OSA4327020
DOSAOs01t0761300-01(Os01g0761300)
OBR102703440
BDI100830101
ATS109753580
TDC119269071 119277064
TAES123062128 123070852 123079242
TUA125528198 125544837
SBI110433879
ZMA100282439
SITA101773389
SVS117855819
PVIR120673087 120708126
PHAI112893888
PDA103706846 103709486
EGU105044446 105047362
MUS103975964
DCT110091939
PEQ110020552
AOF109848382
ATR18426654 18426668
SMOSELMODRAFT_131422 SELMODRAFT_177598
PPP112284600 112296160
VCNVOLCADRAFT_104041
MNGMNEG_8922
CSLCOCSUDRAFT_1836
CVRCHLNCDRAFT_133799 CHLNCDRAFT_29462
APROF751_6027
OLUOSTLU_12975
OTAOT_ostta10g01690
BPGBathy11g01650
MISMICPUN_59981 MICPUN_98438
MPPMICPUCDRAFT_24314 MICPUCDRAFT_52797
GSLGasu_34930
CCPCHC_T00008472001
SLBAWJ20_24(PCS60)
NCRNCU02107
NTENEUTE1DRAFT70536(NEUTE1DRAFT_70536)
SMPSMAC_05001
PANPODANSg09513
TTTTHITE_2121359
MTMMYCTH_2294540
CTHRCTHT_0058440
PPEIPpBr36_00313
SSCKSPSK_05089
FGRFGSG_00287 FGSG_02303 FGSG_07659 FGSG_12922
FPUFPSE_03824 FPSE_04366 FPSE_07026 FPSE_07971 FPSE_10115
FVRFVEG_00344 FVEG_12633
FOXFOXG_01171 FOXG_07378 FOXG_15314
NHENECHADRAFT_31021
TRETRIREDRAFT_106646 TRIREDRAFT_4069 TRIREDRAFT_54667
TRRM419DRAFT_32232 M419DRAFT_34488 M419DRAFT_88629
MAWMAC_00212 MAC_05407 MAC_05529
MAJMAA_04958 MAA_05179 MAA_09853
CMTCCM_07604 CCM_07930
PLJVFPFJ_09993
VALVDBG_03870
VDAVDAG_01098
CFJCFIO01_01577
CLUPCLUP02_13754
CHIGCH63R_05847
SAPOSAPIO_CDS5532
ELAUCREL1_8444
PFYPFICI_06234
SSLSS1G_04708
BFUBCIN_01g08480
MBEMBM_08760 MBM_09235
PSCOLY89DRAFT_683638
GLZGLAREA_11904
NFINFIA_044280
AORAO090023000549
AFVAFLA_006721 AFLA_006894
APUUAPUU_61032S APUU_71250S
PCSPc13g14420
TRGTRUGW13939_05835 TRUGW13939_05837
CIMCIMG_05890 CIMG_08112
CPWCPC735_021270 CPC735_025000
UREUREG_02383 UREG_03795
PBLPAAG_08948
PBNPADG_08572
ABEARB_00727 ARB_06354 ARB_07764
TVETRV_00180 TRV_02925 TRV_07433
PNOSNOG_00119
PTEPTT_18085
BZECOCCADRAFT_10116 COCCADRAFT_107739 COCCADRAFT_34691
BSCCOCSADRAFT_25491 COCSADRAFT_343027
BORCOCMIDRAFT_4043 COCMIDRAFT_7641
AALTCC77DRAFT_1004645 CC77DRAFT_1015556 CC77DRAFT_1066775
ZTRMYCGRDRAFT_70699 MYCGRDRAFT_85953
PFJMYCFIDRAFT_25183 MYCFIDRAFT_60682
FFUCLAFUR5_08572
BCOMBAUCODRAFT_578721 BAUCODRAFT_73329
NPAUCRNP2_5058
CNECNC03230
CNBCNBC3980
CNGCNAG_01836
MBRMONBRDRAFT_26383
SREPTSG_11334
DDIDDB_G0289539
DPPDICPUDRAFT_93333
DFADFA_09639
SMINv1.2.017530.t1(symbB.v1.2.017530.t1) v1.2.017530.t2(symbB.v1.2.017530.t2) v1.2.017530.t3(symbB.v1.2.017530.t3)
PIFPITG_15496
PSOJPHYSODRAFT_555724
SPARSPRG_09682 SPRG_09691
NGRNAEGRDRAFT_38119
PCQPcP3B5_04530(lcfB_1)
PMUIG4G71_01065
PKCPKB_0337
PLALFXN65_26765
MBSMRBBS_2437(lcfB)
MSXAU14_10530
MSQBKP64_09140
MARAD0851_18625
SPSHFM037_08905
SAGAM5M_19200
AFUSEYZ66_09310
THIPN838_01865
AEHMlg_2790
SPIZGJ672_03465
GAIIMCC3135_19245(lcfB_5)
HELHELO_1500(matB)
HAKKO116_00760
HAMHALO0782
HHUAR456_04085 AR456_06405
HCOLOKO_00378(lcfB_1)
HSIBOX17_04930
HALOBWR19_04780
HHHCLM76_07625
HAFC8233_01570
HMDCTT34_16025
HTTHZS52_08745
HCAMI4484_16985
HPIZGYM47_15360
HSXHNO51_16880
HSVHNO53_17230
HTXEKK97_19015
CMAIBFX80_08330
KUSB9G99_15860
KMAB9H00_15775
MMWMmwyl1_3834
MPCMar181_0730
MPRIMP3633_3539
MRHIKDW99_17320
MRZKDW95_22450
LLPGH975_01215
SVASVA_1438
VFFVITFI_CDS3059
RPJN234_16985
REHH16_A2978(h16_A2978)
CNCCNE_1c29280(lcfB6)
CUHBJN34_15925
REUReut_A0648
RMERmet_2794(matB)
CTIRALTA_A2452
CBWRR42_m3294
CGDCR3_0434(matB)
CCUPBKK81_16315
CUPBKK80_17325
CUUBKK79_15025
CPAUEHF44_08935
COXE0W60_23980
PNUPnuc_0631
PDQCL55_00005420
POHDPM16_02330
PTRPDCO17_03765
PPKU875_17795
PPNODA70_10270
PPNMLV28_20820
PRBX636_16615
PPULRO07_15030
PSPUNA29_21995
PAPISG18_15045
PVEUC34_06280
POXMB84_10725
PTXABW99_01830
PFGAB870_17330
PNRAT302_00855
PANDDRB87_05615
PFIBPI93_021995
BPERBN118_2064
BPARBN117_1591
BPABPP1749
BBHBN112_1162
BBRBB3359
BBMBN115_1792
BBXBBS798_3191
BPTBpet3274
BHMD558_2924
BHZACR54_01384(lcfB_1)
BTRMSAMEA390648704172(fadK_3)
BBROBAU06_08350
BFZBAU07_17765
BPDZBBN53_14850
BOHAKI39_08165
BGMCAL15_10885
AXYAXYL_04404
AXONH44784_063891
AXNAX27061_4629
AXXERS451415_04660(fadD_9)
ADTAPT56_21310
AISBUW96_11210
ASWCVS48_23375
ACHRC2U31_16085
ACHBDVB37_17760
ADYHLG70_02110
ACHOH4P35_17095
PUTPT7_0160
PUSCKA81_09115
PUDG9Q38_00480
CDNBN940_13866
ODIODI_R2801
BOZDBV39_07380
PIGEGT29_15140
PARKLSG25_07050
RFRRfer_1925
RSBRS694_07785
RACRA876_07610
RHYRD110_11190
RHFEUB48_08435
RHGEXZ61_11985
POLBpro_2094
PNAPnap_2870
POSDT070_19735
POOF7R28_10825
PVACHC248_01579(lcfB_2)
AAVAave_1515
AJSAjs_1080
AAAAcav_1552
ACKC380_15595
ACRABSY15_37
ACIDCBP33_07595
ACIPCBP36_08165
ACINCBP34_07495
ACISCBP35_10765
ACIOEAG14_07895
AMONH9L24_00620
AANTHUK68_12310
ARADKI609_15055
VEIVeis_2752
DACDaci_2771
DELDelCs14_3986
DTSBI380_09830
DHKBO996_12780
DLAI6G47_10370
VAPVapar_2538
VPEVarpa_3391
VPDVAPA_1c30140
VAAAX767_18520
VAMC4F17_06955 C4F17_30725
CTTCtCNB1_0743 CtCNB1_1807
CTESO987_04015 O987_11295
CSERCCO03_08000
COFFOZ74_03240
CODOLAD35_15560
ADNAlide_3332
ADKAlide2_1115
RTARta_16200
OTKC6570_08975
OTDJ1M35_14005
LIML103DPR2_02108(lcfB_1)
LIHL63ED372_01609(lcfB_2)
HYRBSY239_1434
HYBQ5W_12295
HPSEHPF_14970(lcfB4)
HYNF9K07_16785
HTNKI616_10950
HCZG9Q37_05590
DPYBA022_09815
DIHG7047_03435
DAERH9K75_20445
DRGH9K76_16060
DIADtpsy_0996
SIMPC6571_17595
MELMC7H73_06895
MELAC6568_02340
MJELVC68_06050
KIAG8A07_23260
STHMIS481_13155
PBHAAW51_5509(matB)
SAQAOMP39_15065
MPTMpe_A1101
METPC1M51_02650
RGERGE_43290
RBNRBXJA2T_04523
RDPRD2015_4284
MIUABE85_18240
SNNEWH46_04650
ATERMW290_17165
JAJEKL02_06535
CFUCFU_0894(matB)
CARELT85_1068
CPRACPter91_1049
NOKFAY22_12070
LCHLcho_1293
PKTAT984_01130
RGUA4W93_25270
AONDEH84_04265
TTWLCC91_09090
SHDSUTH_03549
METRBSY238_986
URUDSM104443_02155(lcfB_2)
UPLDSM104440_01983(lcfB_3)
ATWC0099_14740
AZDCDA09_09215
DDZDSYM_28500
BPRCD521_0497
BEBAEM42_08650
BEBABWI17_16085
VINAKJ08_0852
SCLsce7641(fadD4)
SCUSCE1572_44155
PAUUE8A73_014455
SAMYDB32_000790
LLUAKJ09_07510
MRMA7982_08586
SFUSfum_0297
MLOmlr4763
MLNA9174_03475
MCIMesci_0716
MOPMesop_0732
MAMMesau_00699
MAMOA6B35_06115
MESWA9K65_003605
MESMEJ066_15770
MESPC1M53_13750
MHUAMCHK_5834
MJREB229_03565
MERDEB233_03630
MESRFGU64_19085
MOHIHQ72_28285
MESOBSQ44_03250
MESMeso_1586
HOEIMCC20628_03738
PHTBLM14_25065
NIYFQ775_05145
PLAPlav_0422
SMESMa0150
SMKSinme_5419
SMQSinmeB_5481
SMXSM11_pC1666
SMIBN406_05001
SMEGC770_GR4pC1357
SMELSM2011_a0150(matB)
SMERDU99_25025
SMDSmed_5138
RHINGR_b02850
SFHSFHH103_06484(matB)
SFDUSDA257_c22870(lcfB4)
SIXBSY16_3654
SAMESAMCFNEI73_pC1987(lcfB)
SINOSS05631_b50580
EADOV14_a1755
ESJSJ05684_b58570
EAKEKH55_4357
ARAArad_8827(matB)
AVIAvi_5371(fadD)
AVQHRR99_18865
RETRHE_CH00921(matB)
RECRHECIAT_CH0001014(matB)
RELREMIM1_CH00936
REPIE4803_CH00936
REIIE4771_CH00964
RLERL0991(matB)
RLTRleg2_0574
RLGRleg_0616
RLBRLEG3_13280
RLURLEG12_04200
RGARGR602_PC01685
RHNAMJ98_CH00940(matB)
RPHAAMC79_CH00950(matB)
RHXAMK02_CH00964(matB)
RHKKim5_CH01042(matB)
REZAMJ99_CH00940(matB)
RJGCCGE525_09060
RADCO657_02950
RIIFFM53_008240
RHIDFFM81_023685
RLNJ0663_13330
RBANJ2J98_04515
RRGJ3P73_25920
RLSHB780_08235
RAWNE851_14840
RSULN2599_22900
NGLRG1141_PA00200
NGGRG540_PA00210
NEOCYG48_20950
RHTNT26_3780
RFVRFYW14_03664
SZOK8M09_14560
BJAblr0509(blr0509)
BJUBJ6T_04800
BJPRN69_02335
BRABRADO0229
BBTBBta_0226
BRSS23_03280(mcs)
AOLS58_02420 S58_54460
BRCBCCGELA001_01645
BRADBF49_0342
BICLMTR13_37970
BROBRAD285_7516
BRKCWS35_06870
BOTCIT37_11895
BRQCIT40_32910
BGQX265_01695
BGZXH91_02010
BSYMCIT39_31910
BBETF8237_16040
BARHWN72_01745
BVZBRAD3257_0334 BRAD3257_6009
BELBE61_06240
BDGLPJ38_04990
BSEPHAP48_0014495
BQBJ4P68_0018555
BSEIKMZ68_01575
RPARPA0221(matB)
RPBRPB_0329
RPCRPC_0245
RPDRPD_0483
RPERPE_0473
RPTRpal_0220
RPXRpdx1_0415
RBKE0H22_00610
NWINwi_2797
NHANham_3600
OCAOCAR_4285
OCGOCA5_c02360(lcfB1)
OCOOCA4_c02360(lcfB1)
TRBHB776_25085
BOPAXW83_01595
BOSBSY19_1765
BVVBHK69_12290 BHK69_30090
BOIBLM15_12965
BOFFQV39_11335
XAUXaut_0518
XDIEZH22_13845
AZCAZC_3298
SNOSnov_0473 Snov_1580
STARG3545_13025
LNEFZC33_12235
ANCGBB76_07895 GBB76_17780
APRAG3A50_18560
APOLK9D25_00445
MEAMex_1p0644(matB)
MDIMETDI1015(matB)
MEXMext_0876
MCHMchl_0836
MPOMpop_0802
MZAB2G69_11360
MRDMrad2831_1480
METM446_6034
MNOMnod_7251
MORMOC_1856
METAY590_03305
MAQUMaq22A_1p34155(caiC)
MPHYMCBMB27_01125
MEEDA075_08315
METDC0214_03690
METXA3862_23480
METSDK389_14585
METIDK427_10435
MMESMMSR116_31095
MTEADK419_07005
MINDmvi_51450
MOGMMB17_02540
MOCBB934_44750
RHJHZY79_14890
BBARRHAL1_03338
CHELAL346_20245
CDQBOQ54_10920
RVARvan_0326
HDIHDIA_4366(lcfB_2)
AUZSa4125_40560
AUBLXB15_10260
BRND1F64_03790
PSINCAK95_13670
NOHG5V57_02505
TSOIZ6_21880
RBMTEF_13155
PSFPSE_p0160
PPHRAPZ00_19315
LAPACP90_19890 ACP90_22510
LABRCHH27_00375 CHH27_26095
LABPFJ695_21815
LABTFIU93_00255(lcfB1) FIU93_26435(lcfB2)
LAGGB0E33_03610 B0E33_05935
SIWGH266_20675
PHRC6569_03800
PSTGE8M01_13895 E8M01_22175
ACUTMRB58_09670
CMBCSW64_12085
CAULKCG34_23370
PZUPHZ_c1155(matB)
PHBHYN04_04640
SILSPOA0282
SITTM1040_3408
RUAD1823_11410 D1823_21585
RUTFIU92_20935(lcfB2)
RCONK3740_02995 K3740_16300
JANJann_3119
RDERD1_1474
RLIRLO149_c007290
RPONG3256_04055
DSHDshi_2999(fadD1)
PGAPGA1_c34070(lcfB2)
PGLPGA2_c32280(lcfB2)
PGDGal_03474
PHPPhaeoP97_03308
PPICPhaeoP14_03214
PHQD1820_12005
OATOAN307_63p00290(fadD) OAN307_c32090
LMDMETH_20550 METH_22310
LAQUR2C4_18525
LCAEK3721_18040
REDroselon_00588
MALGMALG_00163 MALG_04037
SUAMBOO69_19090
SULZC1J03_01330
SULIC1J05_07310
SULDB5M07_07290
SPOTG6548_06310
SMEDJNX03_12670
SINLDSM14862_01927(lcfB_2)
SPSESULPSESMR1_03807(lcfB)
TOMBWR18_19270
RMMROSMUCSMR3_01451(lcfB)
ROKRAK1035_1715
RIDRIdsm_00016(lcfB_1) RIdsm_00722(lcfB_2)
ROMEI983_02525
ROHFIU89_17595(lcfB6)
AHTANTHELSMS3_00951 ANTHELSMS3_04567
SAGUCDO87_02365 CDO87_19225
THAACFI11_03240
OCDFHY55_08035
MARUFIU81_05060(lcfB3)
ROTFIV09_10540(lcfB4) FIV09_12815(lcfB5)
RMHLVO79_13420 LVO79_19530
MALUKU6B_06430 KU6B_40800
TGLHFZ77_08195 HFZ77_11130 HFZ77_16430
HATRC74_11290
PALXGQA70_17510
LSALKBK07_16870
RSPRSP_1041
RSHRsph17029_2702
RSQRsph17025_3566
RSKRSKD131_2435
CAZTLV780_17925
RBLB6K69_13780
PDEPden_1719
PAMIJCM7686_pAMI5p023
PYEA6J80_15840
PZHCX676_17405 CX676_18185
PAROCUV01_11000
PAMNJCM7685_0003(matB) JCM7685_0679
PARREOJ32_16105
PAAKFIU66_12210
PKDF8A10_18850
PPANESD82_20610
PSANHGN31_15700
PMAUCP157_03346(lcfB_5)
PTPRCA23_c05190(lcfB)
RSUNHU_03359
RHMB5V46_13860
RHCRGUI_2340 RGUI_3229
RMBK529_018600
DAAAKL17_1382
LVSLOKVESSMR4R_00790(lcfB)
RBGBG454_14990
GEHHYN69_02370
GFUKM031_06435 KM031_18375
TAWEI545_14985
SALOEF888_16025 EF888_19195
SEDIEBB79_14460
HMLHmaOT1_14245
BOOE2K80_03495
PSEBEOK75_12740
PPRUFDP22_06330
PAEDG5B38_06625
PAMOBAR1_07040
PSHQF3W81_15715
PPAFI8N54_18420
PGVSL003B_3075
CACTHZ995_01750 HZ995_04780
THASC6Y53_16530
HDHG5B40_05005
CMAGCBW24_17210
GCEKYE46_09750
NSMJO391_09975
ACROK3J57_03825
FAQG5B39_16400
AMAQGO499_10185
NPPPP1Y_AT11028
NPNJI59_06435
NOTC7W88_21010
SWISwit_2492
SPHDHY78_13075
RDICMV14_00280
SLANGV829_00010
SCHYGVO57_07150
BLASBSY18_1693
BFWB5J99_17845
SPHJBSL82_17110
PALGHFP57_09155
SMICSmB9_16260
POQKZX46_22185
AZLAZL_e04090
ALIAZOLI_p50419(matB)
ABSAZOBR_p210027 AZOBR_p310171
ABQABAZ39_24705 ABAZ39_25790
ABFAMK58_23080
ATIAL072_30465
AHUA6A40_14365
AZTTSH58p_00385 TSH58p_31040
AZMDM194_25900
AZZDEW08_02655
AOZHUE56_23305
NAOY958_22930
NCBC0V82_19515
SKTIGS68_01845 IGS68_12795
SMUCJL100_014045 JL100_024830
SROEJL101_011255 JL101_023630
RCERC1_2325
MAGamb3584
MGYMGMSRv2__0206
MGRYMSR1_19930(lcfB_1)
MAGXXM1_1691
MAGNWV31_16465
TMOTMO_0940
FERFNB15_00695
HTQFRZ44_46990
HADHFRZ61_44940
DEXHWD60_15640
TXITH3_06615 TH3_10120
THACCSC3H3_06385 CSC3H3_09845
TIIDY252_09585 DY252_12985
ECOGFIV45_08550
SNEANBZ79_08890
MLIMULP_00983
MTYMTOK_15880
MPOFMPOR_48000
GOQACH46_08125
DIZCT688_09105
SCOSCO2444(SCC24.15)
SALBXNR_2647
SMASAVERM_5723(fadD13)
SGRSGR_5088
SGBWQO_10025
SCBSCAB_63511
SSXSACTE_1911
SHYSHJG_3915
SHOSHJGH_3680
SFASfla_4404
SVESVEN_2231
SDVBN159_5888
SALSSLNWT_5430
STRPF750_2289
SFISFUL_1992
SCIB446_12645
SALUDC74_1642
SALLSAZ_08730
SLVSLIV_25480
SGUSGLAU_11210
SVTSVTN_01340
STREGZL_07509
SCWTU94_10540
SLDT261_7251
SLCSL103_13915
SXISXIM_29310
STRCAA958_04720
SAMBSAM23877_2502
SPRISPRI_5055
SCZABE83_25905
SCXAS200_30375
SRWTUE45_03018(lcfB_3)
STRFASR50_11880
SLEsle_47670(sle_47670)
SRNA4G23_01544(lcfB_3)
SPAVSpa2297_10320
STRTA8713_09495
SCLFBB341_20025
SGSAVL59_39285
STSIA4E84_12750
SKYD0C37_18125
SALWCP975_10915
SGMGCM10017557_57000
SCADDN051_26230
SPHWNFX46_33010
SLSSLINC_2796
SNRSNOUR_34540
SPLULK06_008935
STRDNI25_26805
SNWBBN63_33220
SSIAA7J05_24785 A7J05_33745
SVUB1H20_09115
SPUNBFF78_28895
SGVB1H19_07555
SLAUSLA_2036
SALFSMD44_02668(fadD36)
STROSTRMOE7_06095
SFKKY5_2506
SNZDC008_10445
SGEDWG14_05827(lcfB_3)
SRJSRO_5023
SLKSLUN_12195
SDXC4B68_27570
SGDELQ87_27120
SQZFQU76_08840
SCYAEJ357_14480
SASTCD934_22975
SNQCP978_11565
STIRDDW44_06145
SKACP970_29945
SNKCP967_23820
SHAWCEB94_13190
SFICEIZ62_22910
SGALCP966_11100
SSPODDQ41_05790
SPADDVK44_34985
SFYGFH48_27520
SAQUEJC51_16140
SGFHEP81_05327
SCAVCVT27_08790
SSEOD0Z67_08685
SRIMCP984_35855
SPHVF9278_13110
SCINCP977_10940
SFUGCNQ36_11160
SPACB1H29_25245
STSUB7R87_08730
SCHACP983_29725
SGXH4W23_12515
SCOECP976_14250
SBATG4Z16_00430 G4Z16_27250
SSPBCP982_14145
SPLACP981_04765
SBROGQF42_15110
STUIGCM10017668_20830
SATAC5746_13400
SCHFIPT68_11775
SHUNDWB77_05285(lcfB_4)
SHARHUT13_00365
SCYGS1361_13420(lcfB5)
SFEUIM697_09235
SLIAHA039_01010
SDWK7C20_04140
SVDCP969_13430
SCALI6J39_09395
SAUHSU9_003420
SFBCP974_08780
SPRACP972_11610
SPEUCGZ69_11090
SROIIAG44_27995
SXNIAG42_03205
SGJIAG43_09635
SHKJ2N69_10775
SANUK7396_31315
SDDD9753_24430
SACTDMT42_12610
SMAOCAG99_00265
SGOBtest1122_24880
SINEKI385_07180
SLFJEQ17_31745
SDECL3078_14520
SDURM4V62_07175
KABB7C62_08925
NALB005_4431
NEXNE857_18720
SENSACE_3857(fadD36)
SACGFDZ84_36000
SVISvir_21680
SACCEYD13_11370(lcfB3)
AMDAMED_0746
AMNRAM_03805
AMMAMES_0744
AMZB737_0745
AOIAORI_0729(fadD) AORI_3528(fadD)
AJAAJAP_21500 AJAP_35970
AMQAMETH_0718(fadD36)
AMYCCU254_02290
AMYBBKN51_14860 BKN51_37840
AABA4R43_34235
AMYYYIM_43860(lcfB12)
AORISD37_37525
AACDLWP59_03420
AROONQK81_04870 NQK81_19165
APRECNX65_32150
AMIAmir_6551
SESPBN6_78740
SSYIEKG83_43650
KALKALB_8165
KPHYAOZ06_49405
LEDBBK82_17885 BBK82_37830
ACTAC1701_01160
ALOCRK59959
PMADBAY61_03050
SACEGIY23_15135
SNASnas_0214
AEYCDG81_09155
EUZDVS28_a4677
SYNPSyn7502_02781
CMPCha6605_1276
WNAKA717_19980
CANCyan10605_3248
CYPPCC8801_2136
CYHCyan8802_2184
CYNCyan7425_1330
GVIglr1122
GMLISF26_17365
NPUNpun_R4594
NOSNos7107_4348
NFLCOO91_03131
NEDHUN01_19095
AWAAA650_14050
TOQHCG51_04250
LCREPla8534_16800(lcfB_3)
HHYHalhy_5401
SGNSGRA_2823
AUPAsAng_0024590
ALMAO498_11530
SLISlin_1553
SPIRCWM47_12420
SPIKEXU85_00785
PSEZHME7025_02662
AANHG9X63_05960
ALENG9X62_04740
RSIRunsl_2171
RUNDR864_19545
RUPDTQ70_10620
EOLEmtol_0619
FPFDCC35_19060
RBIRB2501_09090
MARTBTR34_05465
MARBCJ263_08435
 » show all
Reference
1  [PMID:10671542]
  Authors
Gueguen V, Macherel D, Jaquinod M, Douce R, Bourguignon J.
  Title
Fatty acid and lipoic acid biosynthesis in higher plant mitochondria.
  Journal
J Biol Chem 275:5016-25 (2000)
DOI:10.1074/jbc.275.7.5016
Reference
2  [PMID:21846720]
  Authors
Witkowski A, Thweatt J, Smith S
  Title
Mammalian ACSF3 protein is a malonyl-CoA synthetase that supplies the chain extender units for mitochondrial fatty acid synthesis.
  Journal
J Biol Chem 286:33729-36 (2011)
DOI:10.1074/jbc.M111.291591
  Sequence
[hsa:197322]
Reference
3  [PMID:21642549]
  Authors
Chen H, Kim HU, Weng H, Browse J
  Title
Malonyl-CoA synthetase, encoded by ACYL ACTIVATING ENZYME13, is essential for growth and development of Arabidopsis.
  Journal
Plant Cell 23:2247-62 (2011)
DOI:10.1105/tpc.111.086140
  Sequence
[ath:AT3G16170]
Reference
4  [PMID:26836315]
  Authors
Guan X, Nikolau BJ.
  Title
AAE13 encodes a dual-localized malonyl-CoA synthetase that is crucial for mitochondrial fatty acid biosynthesis.
  Journal
Plant J 85:581-93 (2016)
DOI:10.1111/tpj.13130
  Sequence
[ath:AT3G16170]
Reference
5  [PMID:28479296]
  Authors
Bowman CE, Rodriguez S, Selen Alpergin ES, Acoba MG, Zhao L, Hartung T, Claypool SM, Watkins PA, Wolfgang MJ.
  Title
The Mammalian Malonyl-CoA Synthetase ACSF3 Is Required for Mitochondrial Protein Malonylation and Metabolic Efficiency.
  Journal
Cell Chem Biol 24:673-684.e4 (2017)
DOI:10.1016/j.chembiol.2017.04.009
Reference
6  [PMID:30201289]
  Authors
Bowman CE, Wolfgang MJ
  Title
Role of the malonyl-CoA synthetase ACSF3 in mitochondrial metabolism.
  Journal
Adv Biol Regul 71:34-40 (2019)
DOI:10.1016/j.jbior.2018.09.002
Other DBs
ExplorEnz - The Enzyme Database: 6.2.1.76
IUBMB Enzyme Nomenclature: 6.2.1.76
ExPASy - ENZYME nomenclature database: 6.2.1.76
BRENDA, the Enzyme Database: 6.2.1.76

DBGET integrated database retrieval system