KEGG   ENZYME: 7.2.2.13
Entry
EC 7.2.2.13                 Enzyme                                 
Name
Na+/K+-exchanging ATPase;
(Na+ + K+)-activated ATPase;
Na,K-activated ATPase;
Na,K-pump;
Na+,K+-ATPase;
sodium/potassium-transporting ATPase;
Na+/K+-exchanging ATPase
Class
Translocases;
Catalysing the translocation of inorganic cations;
Linked to the hydrolysis of a nucleoside triphosphate
Sysname
ATP phosphohydrolase (P-type, Na+/K+-exchanging)
Reaction(IUBMB)
ATP + H2O + Na+[side 1] + K+[side 2] = ADP + phosphate + Na+[side 2] + K+[side 1]
Substrate
ATP [CPD:C00002];
H2O [CPD:C00001];
Na+[side 1];
K+[side 2]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
Na+[side 2];
K+[side 1]
Comment
A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. This is a plasma membrane enzyme, ubiquitous in animal cells, that catalyses the efflux of three Na+ and influx of two K+ per ATP hydrolysed. It is involved in generating the plasma membrane electrical potential.
History
EC 7.2.2.13 created 1984 EC 3.6.1.37, transferred 2000 to EC 3.6.3.9, modified 2001, transferred 2018 to EC 7.2.2.13
Orthology
K01539  sodium/potassium-transporting ATPase subunit alpha
Genes
HSA: 476(ATP1A1) 477(ATP1A2) 478(ATP1A3) 480(ATP1A4)
PTR: 456068(ATP1A3) 457152(ATP1A1) 457432(ATP1A2) 458010(ATP1A4)
PPS: 100968564(ATP1A2) 100968910(ATP1A4) 100973141(ATP1A3) 100992562(ATP1A1)
GGO: 101132606(ATP1A2) 101133472(ATP1A4) 101136136(ATP1A3) 101154367(ATP1A1)
PON: 100172203(ATP1A2) 100174388(ATP1A1) 100440055(ATP1A3) 100451523(ATP1A4)
NLE: 100585801(ATP1A2) 100586342(ATP1A4) 100596870(ATP1A1) 100604238(ATP1A3)
MCC: 706513(ATP1A3) 710368(ATP1A1) 719623(ATP1A4) 720191(ATP1A2)
MCF: 102122869(ATP1A3) 102124503(ATP1A1) 102144576(ATP1A4) 102145563(ATP1A2)
MTHB: 126930636 126935653 126935658 126941746
CSAB: 103223730(ATP1A4) 103223733(ATP1A2) 103224143(ATP1A1) 103234751(ATP1A3)
CATY: 105589285(ATP1A2) 105589286(ATP1A4) 105596327(ATP1A1) 105598041(ATP1A3)
PANU: 101007483(ATP1A1) 101014462(ATP1A4) 101015462(ATP1A3) 103877144(ATP1A2)
TGE: 112612104(ATP1A3) 112619193 112619203 112623023(ATP1A1)
RRO: 104658863(ATP1A3) 104660405(ATP1A4) 104660406(ATP1A2) 104665933(ATP1A1)
RBB: 108524039(ATP1A4) 108524041(ATP1A2) 108528132(ATP1A1)
TFN: 117074222(ATP1A4) 117074224(ATP1A2) 117075599(ATP1A3) 117075655(ATP1A1)
PTEH: 111530437(ATP1A3) 111543868(ATP1A2) 111543869 111549608(ATP1A1)
CANG: 105505294(ATP1A1) 105507861(ATP1A3) 105522642 105522973(ATP1A4)
CJC: 100393318(ATP1A1) 100402438(ATP1A2) 100403160(ATP1A4) 100410682(ATP1A3)
SBQ: 101035314 101035941(ATP1A2) 101041249(ATP1A1) 101044048(ATP1A3)
CSYR: 103261101(ATP1A4) 103261102 103269847(ATP1A3) 103276099(ATP1A1)
MMUR: 105862683(ATP1A4) 105862687 105867991(ATP1A3) 105869763(ATP1A1)
LCAT: 123624054(ATP1A3) 123635097(ATP1A1) 123635182 123635183
PCOQ: 105817611(ATP1A3) 105821702(ATP1A1) 105824454(ATP1A4) 105824455(ATP1A2)
OGA: 100943178(ATP1A3) 100944949(ATP1A1) 100953795(ATP1A4) 100954113
MMU: 11928(Atp1a1) 232975(Atp1a3) 27222(Atp1a4) 98660(Atp1a2)
MCAL: 110290752(Atp1a1) 110291780(Atp1a4) 110296540 110297290(Atp1a3)
MPAH: 110319913(Atp1a1) 110321177(Atp1a4) 110322617 110337068(Atp1a3)
RNO: 24211(Atp1a1) 24212(Atp1a2) 24213(Atp1a3) 29132(Atp1a4)
MCOC: 116093511(Atp1a1) 116101831(Atp1a3) 116103673(Atp1a4) 116103692
MUN: 110555329 110555333 110556693(Atp1a4) 110556713(Atp1a2) 110566361
CGE: 100758209(Atp1a3) 100763191(Atp1a4) 100763478(Atp1a2) 100771378(Atp1a1)
MAUA: 101828029(Atp1a1) 101828152(Atp1a3) 101844313(Atp1a2) 101844581
PLEU: 114685348(Atp1a3) 114690690(Atp1a2) 114690694 114698572(Atp1a1)
MORG: 121438022(Atp1a1) 121442115(Atp1a2) 121442116 121450099(Atp1a3)
MFOT: 126491478 126502111 126502112 126510793
AAMP: 119800782(Atp1a1) 119821857(Atp1a3) 119827396(Atp1a2) 119827400
NGI: 103734951(Atp1a1) 103740231(Atp1a2) 103740266(Atp1a4) 103744609(Atp1a3)
HGL: 101697634(Atp1a1) 101721060(Atp1a4) 101721146(Atp1a3) 101721770(Atp1a2)
CPOC: 100192382(Atp1a1) 100712985(Atp1a3) 100729524(Atp1a2) 100729796
CCAN: 109681948 109688512(Atp1a3) 109690073(Atp1a4) 109690076
DORD: 105991925(Atp1a1) 105996415 105996538(Atp1a2) 105998060(Atp1a3)
DSP: 122097361(Atp1a3) 122109204(Atp1a4) 122109693 122118322(Atp1a1)
NCAR: 124967385 124979517 124981180
OCU: 100008756(ATP1A2) 100302415(ATP1A1) 100349382 100358269
OPI: 101525499(ATP1A1) 101527265(ATP1A3) 101529459(ATP1A2) 101529874
TUP: 102475448(ATP1A3) 102483255(ATP1A2) 102483994(ATP1A1)
GVR: 103586093(ATP1A3) 103587948(ATP1A4) 103587949(ATP1A2) 103599429(ATP1A1)
CFA: 403992(ATP1A1) 488636(ATP1A4) 612463(ATP1A3)
CLUD: 112642981(ATP1A4) 112645400(ATP1A3) 112664143(ATP1A1) 125752062
VVP: 112910077 112910081 112916773(ATP1A1) 112931443(ATP1A3)
VLG: 121471339(ATP1A2) 121471981 121485787(ATP1A3) 121490989(ATP1A1)
AML: 100477585(ATP1A3) 100477989(ATP1A1) 100480641 100480890(ATP1A4)
UMR: 103669413(ATP1A1) 103672049(ATP1A4) 103672113(ATP1A2) 103680185(ATP1A3)
UAH: 113243247(ATP1A3) 113244381(ATP1A1) 113246653(ATP1A4) 113246737
UAR: 123783365(ATP1A2) 123783612 123795027(ATP1A1) 123798066(ATP1A3)
ELK: 111138822 111138823 111139490 111143264
LLV: 125085919 125086256 125089713 125097511
MPUF: 101677161(ATP1A3) 101678357(ATP1A2) 101678857(ATP1A4) 101689482(ATP1A1)
ORO: 101366083(ATP1A1) 101376936(ATP1A3) 101379349(ATP1A2) 101379646(ATP1A4)
EJU: 114197049(ATP1A3) 114199132(ATP1A2) 114199201 114208034(ATP1A1)
ZCA: 113926396(ATP1A1) 113933054(ATP1A2) 113933076 113936608(ATP1A3)
MLX: 117997950(ATP1A3) 118000481(ATP1A1) 118013976(ATP1A2) 118013977
NSU: 110573336(ATP1A2) 110573415 110580523(ATP1A1) 110582287(ATP1A3)
LWW: 102738746 102743274(ATP1A3) 102749975 102750268(ATP1A4)
FCA: 101083636(ATP1A3) 101083695(ATP1A1) 101096375(ATP1A4) 101096785
PYU: 121015507 121015508 121027760(ATP1A1)
PBG: 122476358(ATP1A4) 122476359 122480994(ATP1A1) 122493969(ATP1A3)
LRUF: 124511730 124514655 124521784 124521786
PTG: 102954810 102955336(ATP1A3) 102955398 102971148(ATP1A1)
PPAD: 109257219 109257221(ATP1A2) 109257944(ATP1A3) 109272127(ATP1A1)
AJU: 106969643(ATP1A1) 106978517(ATP1A4) 106985576 106987698(ATP1A3)
HHV: 120238762(ATP1A1) 120241370(ATP1A4) 120241371(ATP1A2) 120243678(ATP1A3)
BTA: 282144(ATP1A1) 282598(ATP1A3) 515161(ATP1A2) 537960(ATP1A4)
BOM: 102270922(ATP1A3) 102271837(ATP1A2) 102272122(ATP1A4) 102287260(ATP1A1)
BIU: 109555876(ATP1A1) 109571737(ATP1A3) 109578704(ATP1A4) 109578722
BBUB: 102396896(ATP1A3) 102404308(ATP1A1) 102405290(ATP1A2) 102405960(ATP1A4)
BBIS: 104981569(ATP1A1) 104993565(ATP1A2) 104993570(ATP1A4) 105005136(ATP1A3)
CHX: 102179588(ATP1A3) 102183561(ATP1A1) 102186069 102186539
OAS: 101103751(ATP1A3) 101118148(ATP1A2) 101118398 443381(ATP1A1)
ODA: 120855582(ATP1A2) 120855583(ATP1A4) 120856023(ATP1A1) 120872368(ATP1A3)
CCAD: 122420162(ATP1A3) 122430948(ATP1A4) 122430955 122435720(ATP1A1)
SSC: 100157711 100329126(ATP1A3) 396828(ATP1A2) 397481(ATP1A1)
CFR: 102509736(ATP1A1) 102516053(ATP1A2) 102516646(ATP1A4) 102517975(ATP1A3)
CBAI: 105062463(ATP1A3) 105069515 105069516 105079466(ATP1A1)
CDK: 105089616(ATP1A1) 105090227(ATP1A3) 105100141(ATP1A2) 116147050(ATP1A4)
VPC: 102529041(ATP1A3) 102537426(ATP1A1) 102542176 102542760
BACU: 102998568(ATP1A1) 103005321(ATP1A4) 103005600(ATP1A2) 103011003(ATP1A3)
LVE: 103068908(ATP1A3) 103074614(ATP1A4) 103074894(ATP1A2) 103085693(ATP1A1)
OOR: 101279507(ATP1A1) 101280223(ATP1A3) 101288540(ATP1A4) 101288792(ATP1A2)
DLE: 111166986 111166987 111179983(ATP1A1) 111180802(ATP1A3)
PCAD: 102981487 102982135 102983659(ATP1A1) 102985775(ATP1A3)
PSIU: 116738896(ATP1A1) 116742064(ATP1A2) 116744406(ATP1A3) 116755861
ECB: 100034139(ATP1A1) 100058251(ATP1A2) 100058301(ATP1A4) 100069796(ATP1A3)
EPZ: 103543741 103547749(ATP1A1) 103551135(ATP1A4) 103551139(ATP1A2)
EAI: 106835689(ATP1A1) 106835754(ATP1A4) 106835755 106847933(ATP1A3)
MYB: 102242637(ATP1A3) 102243691(ATP1A1) 102243972(ATP1A4) 102244267(ATP1A2)
MYD: 102757270(ATP1A2) 102757556(ATP1A4) 102762810(ATP1A3) 102770472(ATP1A1)
MMYO: 118673132(ATP1A2) 118673235 118673770(ATP1A1) 118674644(ATP1A3)
MLF: 102417711 102420715(ATP1A3) 102429118(ATP1A2) 102432129(ATP1A1) 102441641
MNA: 107534181(ATP1A3) 107538456 107545330(ATP1A1)
PKL: 118702301(ATP1A3) 118721573(ATP1A2) 118721574 118727140(ATP1A1)
HAI: 109374464(ATP1A3) 109386501(ATP1A2) 109392813(ATP1A1)
DRO: 112313776(ATP1A1) 112315807 112317734(ATP1A2) 112320186(ATP1A3)
SHON: 118982030(ATP1A1) 118996417 118996431 119000480(ATP1A3)
AJM: 119041702(ATP1A1) 119048466 119048473(ATP1A4) 119060145(ATP1A3)
PDIC: 114489216(ATP1A1) 114511606(ATP1A3) 114511824(ATP1A2) 114511839
PHAS: 123804299(ATP1A1) 123818256(ATP1A3) 123820560(ATP1A2) 123820599
MMF: 118636912 118637061(ATP1A2) 118637940(ATP1A1) 118638724(ATP1A3)
RFQ: 117014324(ATP1A1) 117014362 117035060(ATP1A3)
PALE: 102884868(ATP1A4) 102885125 102888359(ATP1A1) 102893697(ATP1A3)
PGIG: 120584288(ATP1A4) 120584290 120585084(ATP1A1) 120592362(ATP1A3)
PVP: 105297909(ATP1A1) 105300714(ATP1A4) 105300716 105307345(ATP1A3)
RAY: 107499819(ATP1A1) 107502600(ATP1A3) 107507949(ATP1A2) 107507966(ATP1A4)
MJV: 108390973(ATP1A1) 108393642(ATP1A3) 108402828 108402834
TOD: 119237084(ATP1A1) 119241403 119241404 119249373(ATP1A3)
SARA: 101539786 101540228(ATP1A2) 101549509(ATP1A3) 101555668(ATP1A1)
LAV: 100661428(ATP1A1) 100667801 100668326(ATP1A3) 100674070(ATP1A2)
TMU: 101345071 101355408 101361490 101361788
ETF: 101648011(ATP1A2) 101648541 101651601(ATP1A3) 101659884(ATP1A1)
DNM: 101413464 101416281(ATP1A1) 101444307(ATP1A4) 101445509
MDO: 100029754(ATP1A4) 100029759(ATP1A2)
GAS: 123240805(ATP1A3) 123244129(ATP1A1) 123246045 123247014
SHR: 100914130(ATP1A2) 100918637 100922123(ATP1A3) 100928210(ATP1A1)
PCW: 110203112(ATP1A2) 110203115 110219354(ATP1A1) 110220180(ATP1A3)
OAA: 100083795 100088125(ATP1A3) 100088592(ATP1A1) 103166927
GGA: 396530(ATP1A1)
PCOC: 116238833 116242449(ATP1A1)
MGP: 100303690(ATP1A1) 104915899
CJO: 107307592 107319786(ATP1A1) 107324341
NMEL: 110399227(ATP1A1)
APLA: 101801864(ATP1A1)
ACYG: 106029333 106037472(ATP1A1)
AFUL: 116494087(ATP1A1)
TGU: 100190719(ATP1A1) 105760330
LSR: 110479065 110480864(ATP1A1) 110482576
SCAN: 103827109(ATP1A1)
PMOA: 120504822 120506317(ATP1A1)
OTC: 121339036 121339371(ATP1A1)
PRUF: 121351728(ATP1A1) 121359325
GFR: 102036467(ATP1A1)
FAB: 101813002(ATP1A1) 101813385
PHI: 102104980 102106372(ATP1A1) 102107817
PMAJ: 107207264(ATP1A1)
CCAE: 111938980(ATP1A1)
CCW: 104687046(ATP1A1)
CBRC: 103613884(ATP1A1) 103620065(ATP1A3)
ETL: 114055106(ATP1A1)
ZAB: 102068623
ACHL: 103799318
FPG: 101914787(ATP1A1) 101915017(ATP1A2)
FCH: 102050259(ATP1A1) 102059303(ATP1A2)
CLV: 102092496(ATP1A1) 102093141
EGZ: 104126505(ATP1A1)
NNI: 104008633(ATP1A1) 104012600(ATP1A2)
PLET: 104617469
PCRI: 104028940
PCAO: 104045670
ACUN: 113485715
TALA: 104360151(ATP1A1) 116959234
PADL: 103921389(ATP1A1)
AFOR: 103895053(ATP1A1) 103900544(ATP1A2)
ACHC: 115343638(ATP1A1) 115346177
HALD: 104320232
HLE: 104831341 104831705(ATP1A1)
AGEN: 126041044 126048933
GCL: 127029534
CCRI: 104165105
CSTI: 104554900
EHS: 104508023
CMAC: 104480673
MUI: 104546929
FGA: 104083290
GSTE: 104258531
LDI: 104345447
MNB: 103778074
OHA: 104335838(ATP1A1)
NNT: 104409512
DPUB: 104298659
PGUU: 104467518
ACAR: 104523381
CPEA: 104389254(ATP1A1) 104398477(ATP1A2)
AVIT: 104270834
CVF: 104281849(ATP1A1)
CUCA: 104055812(ATP1A1) 104057909
TEO: 104384027(ATP1A1)
BRHI: 104498165
AAM: 106490649(ATP1A1) 106500059(ATP1A2)
AROW: 112962167 112963983 112965930
NPD: 112955223 112956869(ATP1A1)
TGT: 104566944(ATP1A1) 104570244
DNE: 112989406(ATP1A1) 112997239
SCAM: 104139719 104144322(ATP1A1)
ASN: 102371189 102372830(ATP1A1) 102376674
AMJ: 102567591(ATP1A1) 102575084(ATP1A2) 106737151
CPOO: 109314483(ATP1A3) 109319226(ATP1A1)
GGN: 109304290(ATP1A1)
PSS: 102460622 102462326
CMY: 102936217(ATP1A1) 102938341
CPIC: 101931556(ATP1A3) 101933418(ATP1A1) 101950302
TST: 117869615 117886721(ATP1A1)
CABI: 116819843 116834317 116836361
MRV: 120390167 120390183(ATP1A3) 120400237(ATP1A1)
ACS: 100554397 100557516(atp1a2) 100564542
PVT: 110076957 110081459 110086767(ATP1A3) 110087403
SUND: 121915398(ATP1A3) 121915467 121916840 121921395(ATP1A1)
PBI: 103051176 103054113 103058247(ATP1A3) 103063371
PMUR: 107289344(ATP1A1) 107298220 107299011(ATP1A3)
CTIG: 120296669 120311998(ATP1A3) 120316535 120318645(ATP1A1)
TSR: 106540363 106551896 106553286(ATP1A3)
PGUT: 117657954 117661891(ATP1A1) 117670090 117677582(ATP1A3)
VKO: 123019603 123023542 123025794(ATP1A3) 123034800(ATP1A1)
PMUA: 114585062 114586449 114587332(ATP1A1) 114603364(ATP1A3)
ZVI: 118075785 118086200(ATP1A3) 118097087 118097547(ATP1A1)
GJA: 107109259(ATP1A1) 107122231 107126069
STOW: 125435873(ATP1A3) 125436056 125439894
XLA: 108697760 108699431(atp1a2.L) 380132(atp1a3.L) 398583(atp1a1.S) 398752(atp1a2.S) 399285(atp1a1.L)
XTR: 100125050(atp1a2) 100145440(atp1a3) 395044(atp1a1)
NPR: 108785659(ATP1A3) 108801111 108802354
RTEM: 120916383(ATP1A3) 120920663 120921642(ATP1A1)
BBUF: 120981733 120990871(ATP1A3) 120994305(ATP1A1)
BGAR: 122921494 122922716 122929152(ATP1A3)
DRE: 245703(atp1a1a.5) 64609(atp1a2a) 64610(atp1a3a) 64611(atp1a3b) 64612(atp1a1a.1) 64613(atp1a1a.2) 64614(atp1a1a.3) 64615(atp1a1a.4) 64616(atp1a1b)
SRX: 107717437 107717912 107717913 107718011 107718012 107721700 107723432 107749099 107753791 107756749
SANH: 107653678 107653679 107656784 107659860 107665151 107666333 107671176 107692876 107698889 107698904 107698905 107698906 107700181
SGH: 107549859 107551687 107555257 107555258 107555259 107555265 107557871 107568774 107568776 107569141 107582039
CCAR: 109060282 109060283 109060287 109062485 109105196
CAUA: 113044615 113044616 113044617 113045082 113053072 113059992 113060017 113062584 113080289 113083311 113098330 113098407 113116416 113119857 113120983
PPRM: 120460487 120460488 120460489 120460490(atp1a1a.2) 120483688 120484352(atp1a3b) 120490367(atp1a1b) 120495259(atp1a2a)
MAMB: 125242886(atp1a3b) 125250487(atp1a2a) 125269314 125270184(atp1a1b) 125272943 125272945(atp1a1a.2) 125272946 125272947 125275671(atp1a3a)
IPU: 108258574 108258575 108258576 108258577 108258578 108261056(atp1a2a) 108266346(atp1a3b) 108266666(atp1a1b) 108272709(atp1a3a)
PHYP: 113524226 113533230 113534892 113537353 113537465 113537466 113537467 113542326(atp1a3)
SMEO: 124378173 124378174 124378175 124378176 124381816(atp1a3a) 124384039(atp1a3b) 124403322(atp1a2a)
TFD: 113643561(atp1a3b) 113648762 113649012 113649014 113649015 113653825(atp1a3a) 113654455(atp1a1b) 113662123(atp1a2a)
AMEX: 103023580 103024756 103026980 103030580 103034051(atp1a3) 103044221 107197318
EEE: 113568013 113581248 113582621 113582623 113582624 113582625 113583247 113588966
TRU: 101065136 101066343 101066712 101075427 101078763
TNG: GSTEN00008580G001 GSTEN00011875G001 GSTEN00012164G001 GSTEN00015288G001
LCO: 104922250 104926550 104928331 104929040
NCC: 104944632 104956617 104966979 104967149
CGOB: 115016114 115017562 115017719 115021347 115022139
ELY: 117250162 117250223 117263377(atp1a3a) 117265974(atp1a3b) 117271639(atp1a2a)
EFO: 125884964 125884965 125893090(atp1a3b) 125901777(atp1a2a) 125905316(atp1a3a)
PLEP: 121945226(atp1a3b) 121951800(atp1a2a) 121957722(atp1a3a) 121962711 121962712
SLUC: 116040546(atp1a2a) 116044414 116044417 116047081(atp1a3a) 116049754(atp1a3b)
ECRA: 117939433 117939434 117939435 117939437 117946187(atp1a3b) 117953611(atp1a2a) 117956667(atp1a3a)
ESP: 116674133 116674134 116674135 116674136 116691204 116699713
PFLV: 114550887 114550888 114550889 114550891 114557456 114565051 114568249
GAT: 120810803(atp1a3b) 120815788(atp1a2a) 120823906 120823921 120826859
PPUG: 119197208(atp1a3b) 119205402(atp1a2a) 119219229(atp1a3a) 119219831 119219839 119219846 119219852
MSAM: 119897389(atp1a3b) 119901745(atp1a2a) 119904401 119904410 119907432(atp1a3a)
CUD: 121506161 121506174 121513482(atp1a3b) 121519836(atp1a2a) 121523345(atp1a3a)
ALAT: 119006300(atp1a3b) 119011014(atp1a2a) 119015063 119015089 119016812(atp1a3a)
MZE: 101473612 101476311 101476791 101477070 101477348 101477629 101481172 101487824
ONL: 100692262 100694151 100699477 100707930 100712391 112841652
OAU: 116312245 116312246 116312247 116312248 116312264 116323746(atp1a3b) 116331918(atp1a3a) 116332081(atp1a2a)
OLA: 100049445 101156309 101159291 101161996 101166845 101168472
OML: 112143633(atp1a3b) 112151412(atp1a2a) 112156656 112156657 112161935(atp1a3a)
XMA: 102217063 102218145 102222505 102231053 102236496
XCO: 114138859(atp1a3) 114140845 114140846 114145806 114155959
XHE: 116716130 116716131 116716798(atp1a3) 116722273 116731296
PRET: 103472959 103473267 103473276 103477950(atp1a3) 103479499
PFOR: 103136798 103137992 103143433 103148705 103148706
PLAI: 106949645 106955593 106959198 106959199 106960171 106962313
PMEI: 106917865 106919873 106919874 106926231 106930725 106933341
GAF: 122827365 122827368 122831080(atp1a3b) 122841814(atp1a2a) 122843578(atp1a3a)
CVG: 107082214(atp1a3) 107084232 107086738 107092351
CTUL: 119779563(atp1a2a) 119780786 119780787 119783037(atp1a3b) 119795003(atp1a3a)
GMU: 124861351 124861774 124861835 124866258(atp1a3b) 124869275(atp1a2a) 124879011(atp1a3a)
NFU: 107377204 107377205 107379502 107383461 107394873
KMR: 108232880(atp1a2a) 108235385(atp1a3b) 108242195 108242200 108242662(atp1a3a)
ALIM: 106519560 106520798 106521034(atp1a3) 106525268 106525269 106536549
NWH: 119409315(atp1a3b) 119415241(atp1a2a) 119425815(atp1a3a) 119428748 119428755(atp1a1a.4)
AOCE: 111563192 111565636 111565637 111572387 111574622
MCEP: 125000845 125000846 125010483(atp1a2a) 125016402(atp1a3b) 125019818(atp1a3a)
CSEM: 103387990(atp1a3) 103389243 103393877 103396779 103396780
POV: 109633230 109639148 109640219 109640221 109640521
SSEN: 122758131(atp1a1a.1) 122758605(atp1a1a.4) 122769140(atp1a2a) 122775031(atp1a3b) 122786298(atp1a3a)
HHIP: 117770917(atp1a3a) 117776767(atp1a3b) 117777835 117777837 117777887(atp1a2a)
HSP: 118103433 118103458 118113162(atp1a3b) 118117534(atp1a2a) 118124577(atp1a3a)
LCF: 108873016 108873017 108880671(atp1a3b) 108881918 108884323(atp1a2a)
SDU: 111220823 111230037 111233654 111233662 111239378
SLAL: 111645617 111665251 111665362 111668406 111672471
XGL: 120784055(atp1a3b) 120786164(atp1a3a) 120798093 120798101 120798710(atp1a2a)
HCQ: 109507251 109507252 109518390 109529483 109531678
BPEC: 110170895 110170919 110172175 110174490 110175127
MALB: 109966232 109970717 109971950 109971953 109971968 109974490
BSPL: 114842899(atp1a3b) 114844511(atp1a2a) 114846791 114851185 114865536(atp1a3a)
SASA: 100136390(ATP1A1) 100380633(ATP1A1C/ii) 106569580 106569974 106574724(ATP1A1C/i) 106575572(AT1A1) 106583316 106588414 106596139 106596208 106600489(ATP1A2) 106602157(ATP1A1A) 106602248 106605102 106610479
STRU: 115157489 115169311 115173532 115175937 115176589 115177268 115179374 115179375 115190437 115196287 115196288 115202425
OTW: 112223108 112226568 112233288 112237535(atp1a2a) 112240137 112246559 112253654 112255118 112264803 112266352 112266353
OMY: 100136182(atp1a2a) 100136183 100136184 100136185 100136657(atp1a3) 110488366 110495657 110495658 110496211(atp1a3a) 110497251 110508325 110517766
OGO: 123997567 124005438 124007714 124009310 124010456 124010457 124012027 124041634 124043551
ONE: 115102829 115119455 115131627 115132097 115132105
SALP: 111955661 111970831 111974345 111979355 112081173
SNH: 120020104 120022454 120027189 120031067 120033134 120034694 120048311 120051421 120055668(atp1a2a)
CCLU: 121535438 121558098 121559770 121560329 121562186 121571562 121581286 121586446 123481327
ELS: 105016395 105019473 105019783 105019784 105019842 105020902 105024506 105024552 105028252 105028600
SFM: 108922112(atp1a3) 108926579 108931711 108931712 108937926 108938015
PKI: 111833136 111836459 111836461 111839715 111842914(atp1a3) 111855672 111855680
AANG: 118214180 118223159 118223363 118225750(atp1a3b) 118233851(atp1a2a) 118234122
LOC: 102682810 102689287 102689494 102690797(atp1a2)
PSPA: 121298585 121304271 121307362 121320726 121320727 121321082 121327697 121327885
ARUT: 117398843 117405302 117406750 117407306 117434008 117962584 117962776 117973056
PSEX: 120519909 120521267 120524373 120541471(atp1a3b)
LCM: 102352604(ATP1A2) 102353554(ATP1A1) 102356851(ATP1A3)
CMK: 103177451 103191236
RTP: 109925852 109936274
BFO: 118424338
BBEL: 109484030
CIN: 100175029 101243505
SCLV: 120326521
SPU: 115917979 404637
APLC: 110976714
AJC: 117101018
SKO: 100370816(ATP1A1)
DME: Dmel_CG45062(CG45062) Dmel_CG45760 Dmel_CG5670(Atpalpha)
DER: 6546701 6553483 6555881
DSE: 116800548 6620080
DSI: Dsimw501_GD19388(Dsim_GD19388) Dsimw501_GD19691(Dsim_GD19691) Dsimw501_GD29095(Dsim_GD29095)
DYA: Dyak_GE11863 Dyak_GE14534 Dyak_GE25699
DAN: 6500777
DSR: 110177248 110178401
DPO: 4801538 4804463 6902253
DPE: 6592390 6597691 6604641
DMN: 108155631 108159220 108164908
DWI: 111518345 6637464 6648127
DGR: 6559706 6567570
DMO: Dmoj_GI10755 Dmoj_GI18976 Dmoj_GI21352
DAZ: 108613914 108614932 108620382
DNV: 108651474 108652780 115565445
DHE: 111595247 111603492
DVI: 6632311
CCAT: 101448826
BOD: 106616042
RZE: 108353928 108356039 108365466 108368096 108372468 108373569 108374948 108374949 108375829 108380628 108382108 108383198
MDE: 101893028
SCAC: 106093479
LCQ: 111678276
LSQ: 119601620
HIS: 119650690
AGA: AgaP_AGAP002858
ACOZ: 120950886
AARA: 120897925
ASTE: 118504398
AAG: 5575790
AALB: 109621302 115269307
CQU: CpipJ_CPIJ005966
CPII: 120429815
CNS: 116345415
BCOO: 119067170 119076733 119083249
AME: 410913 411083 413471
ACER: 107997582 108001106 108002557
ALAB: 122710465 122712799 122715186
BIM: 100740458 100745576 112212010
BBIF: 117205459 117206077 117213932
BVK: 117235603 117236398 117237222
BVAN: 117153934 117159306 117161449
BTER: 100643682 100647333 110119661
BPYO: 122567594 122573063 122577956
CCAL: 108628552 108631707 113464117
OBB: 114871699 114876493 114879608
MGEN: 117223563 117226724 117229405
NMEA: 116423924
CGIG: 122398658 122400886 122403854
SOC: 105200410 105204687
MPHA: 105834192 105835345 105836458
AEC: 105143877 105144349 105151970
ACEP: 105619192 105620558
PBAR: 105423550 105431091 105433424
VEM: 105565877 105566725 105570710
HST: 105182517 105189690 105191858
DQU: 106745026 106745280 106746158
CFO: 105252935 105255730
FEX: 115240353 115240655 115242877
LHU: 105668079 105675982
PGC: 109856722 109859893
OBO: 105282988 105286167
PCF: 106787185 106790351
PFUC: 122523135 122523571
VPS: 122629829 122635380
NVI: 100116320
CSOL: 105367030 105367538
TPRE: 106656171 111693978
MDL: 103572337 103575003
CGLO: 123259266 123260458
FAS: 105267415 105267792 105268209
DAM: 107038842 107043645 107046889
AGIF: 122854762 122858425 122859756
CINS: 118065703 118067402
LHT: 122497701 122498848
CCIN: 107262933 107269732 107273910
TCA: 660125 661036 661092 663833
DPA: 109541511 109543820
SOY: 115879239 115888078
ATD: 109601843 109601910 109606095
CSET: 123308563 123317247 123319215
AGB: 108904109 108906661 108911543
LDC: 111506087 111514155
NVL: 108559172 108567364 108567920
APLN: 108734671 108734676 108738656
PPYR: 116172282 116178353
OTU: 111415914 111419384 111429126
BMOR: 101741043 101741364 101743662
BMAN: 114243712 114250881 114253235
MSEX: 115443664 115446900 115449115
DPL: KGM_211186 KGM_213623
BANY: 112043125 112058377
NIQ: 126774125 126775938 126780602
PMAC: 106718188 106719104 106721608
PPOT: 106103840 106109674
PXU: 106118927 106120084 106121330
PRAP: 110992182 110993096 110993542
PBX: 123708862 123715307 123716161
PNAP: 125049363 125052697 125057015
ZCE: 119828210 119828807 119832607
CCRC: 123694631 123695553 123699981
HAW: 110370047 110379225 110380431
HZE: 124633573 124634984 124640046
TNL: 113492102 113498884 113501274
SLIU: 111350557 111359764 111362360
OFU: 114356111 114360261 114361635
PXY: 105380390 105384743 105384761 105393938 105395060 105395131
CFEL: 113378082
API: 100167886 103310367
DNX: 107162558 107166340
AGS: 114121167 114131348
RMD: 113556602 113560363
BTAB: 109030222 109036610
DCI: 103507789 103508421 103518361
CLEC: 106667156
HHAL: 106678115
NLU: 111043643 111055653
PHU: Phum_PHUM336910 Phum_PHUM361900 Phum_PHUM432700
FOC: 113207579 113210068 113213278
TPAL: 117641999 117643915
ZNE: 110827645
CSEC: 111866732
SGRE: 126361668
FCD: 110842637 110844556 110844776 110845146 110847285 110850393 110850883 110852009 110852162 110860604 110860635
DPX: DAPPUDRAFT_202800 DAPPUDRAFT_256165 DAPPUDRAFT_305634 DAPPUDRAFT_305693 DAPPUDRAFT_309219 DAPPUDRAFT_60674
DMK: 116918745 116926487 116926657 116928070
DPZ: 124315125 124315130 124326056 124326057 124326058 124344411
PVM: 113815921 113815924
PJA: 122242743
PCHN: 125027414
HAME: 121869643
PCLA: 123775277 123775292 123775293 123775295 123775297
PTRU: 123501184
HAZT: 108679958
EAF: 111695922 111697881 111702178 111706151 111707294 111708601 111716138
LSM: 121113844 121116349 121116855 121116857 121116860 121116893
PPOI: 119089746 119112783
ISC: IscW_ISCW002538
DSV: 119455962
RSAN: 119394018
RMP: 119172146
VDE: 111243955 111253468
VJA: 111272716 111273134
TUT: 107360911 107362336 107362522 107368464
DPTE: 113789308 113791130 113792575 113794371 113796956 113798706
DFR: 124490396 124492605 124496647 124497296 124497499 124498391
CSCU: 111621442 111622934 111622935
PTEP: 107439305 107456567 107456568 107457342
SDM: 118181987 118182892 118184367 118185457 118203405
CEL: CELE_B0365.3(eat-6) CELE_C01G12.8(catp-4) CELE_C02E7.1(catp-2) CELE_Y105E8A.12(catp-1)
CBR: CBG_01656 CBG_08751(Cbr-catp-1) CBG_09434(Cbr-eat-6)
BMY: BM_BM10442(Bma-catp-4) BM_BM1779(Bma-eat-6) BM_BM8870(Bma-catp-1)
LOA: LOAG_07482 LOAG_07650 LOAG_17214 LOAG_17981
NAI: NECAME_01244 NECAME_03149 NECAME_03351
TSP: Tsp_02677 Tsp_04833
HRO: HELRODRAFT_102867 HELRODRAFT_156333 HELRODRAFT_157527 HELRODRAFT_157737 HELRODRAFT_185638 HELRODRAFT_187047 HELRODRAFT_188923 HELRODRAFT_94922 HELRODRAFT_94925
LGI: LOTGIDRAFT_169374
PCAN: 112556672 112557518 112567690 112567977 112567978
BGT: 106057146 106058316 106058320 106058321 106058322 106059667
GAE: 121386257
HRF: 124124929
HRJ: 124285208
CRG: 105338008
MYI: 110459295
PMAX: 117341055
MMER: 123544607 123559667
OBI: 106880261
OSN: 115211699
LAK: 106151073 106170273
SMM: Smp_015020 Smp_130300
SHX: MS3_00009405 MS3_00009412(ATP1A1_1)
OVI: T265_12551 T265_14207
EGL: EGR_08003
NVE: 5507906 5512402
EPA: 110241818 110242299
ATEN: 116291703 116297980
ADF: 107343492
AMIL: 114971434 114971437
PDAM: 113672492 113672497
SPIS: 111336997 111337981
DGT: 114524594
XEN: 124445428
HMG: 100197585 100205960 100209230 100209869 100210266 100212925 100213157 105846521
TAD: TRIADDRAFT_63163
AQU: 100634317
QSU: 111989924
VCN: VOLCADRAFT_78789
CVR: CHLNCDRAFT_56139
OLU: OSTLU_48492
OTA: OT_ostta01g00890
BPG: Bathy01g00820
CCP: CHC_T00002703001 CHC_T00009537001
PIC: PICST_60178(PMR2)
CAL: CAALFM_CR01630CA(CaO19.2552) CAALFM_CR01640CA(CaO19.2553)
CTEN: CANTEDRAFT_102766
CAUR: CJI97_001729
SLB: AWJ20_4150(PMR1)
PAN: PODANSg1282 PODANSg8259
TTT: THITE_125028 THITE_2118086
MGR: MGG_10027 MGG_16361
PPEI: PpBr36_07903 PpBr36_10247
TMN: UCRPA7_4282
SSCK: SPSK_03931 SPSK_08368 SPSK_10740
FGR: FGSG_04512
FPU: FPSE_03734
FVR: FVEG_09346 FVEG_11139
FOX: FOXG_10689 FOXG_13707 FOXG_21238
NHE: NECHADRAFT_103674 NECHADRAFT_71444 NECHADRAFT_85426
TRE: TRIREDRAFT_106928
TRR: M419DRAFT_77664
MAW: MAC_01563 MAC_06634
MAJ: MAA_02399 MAA_07893
CMT: CCM_01962 CCM_03289
PLJ: VFPFJ_02578 VFPFJ_07339 VFPFJ_10236
VAL: VDBG_02452
VDA: VDAG_02927
CFJ: CFIO01_09611
CLUP: CLUP02_11533
CHIG: CH63R_11070
SAPO: SAPIO_CDS10330
ELA: UCREL1_3885
PFY: PFICI_03211 PFICI_13920
SSL: SS1G_00628
BFU: BCIN_03g02800 BCIN_13g00870
MBE: MBM_04409
PSCO: LY89DRAFT_587961 LY89DRAFT_695593 LY89DRAFT_773458
GLZ: GLAREA_07211
ANI: AN8941.2
AFM: AFUA_5G00730 AFUA_7G04570
ACT: ACLA_004560 ACLA_006260
NFI: NFIA_025530 NFIA_041430
AOR: AO090005000141 AO090038000088
ANG: ANI_1_1014084(An09g00930) ANI_1_352124(An14g02290)
AFV: AFLA_002924 AFLA_012360
ALUC: AKAW2_40072S
APUU: APUU_41422S
PCS: Pc21g08760
PDP: PDIP_58430
TMF: PMAA_006120 PMAA_057370
TRG: TRUGW13939_00915 TRUGW13939_07346
URE: UREG_03834
PBL: PAAG_04243
PBN: PADG_07481
ABE: ARB_01038 ARB_06970
TVE: TRV_00354 TRV_02788
PNO: SNOG_00706
PTE: PTT_00480
BZE: COCCADRAFT_81950 COCCADRAFT_84757
BSC: COCSADRAFT_349006 COCSADRAFT_354769
BOR: COCMIDRAFT_5291 COCMIDRAFT_88396
AALT: CC77DRAFT_1056004
ZTR: MYCGRDRAFT_70478
PFJ: MYCFIDRAFT_163458
FFU: CLAFUR5_06118
BCOM: BAUCODRAFT_144399 BAUCODRAFT_38353
NPA: UCRNP2_6234
TASA: A1Q1_02917
TVS: TRAVEDRAFT_30295 TRAVEDRAFT_36490
DSQ: DICSQDRAFT_110606 DICSQDRAFT_156959 DICSQDRAFT_161018 DICSQDRAFT_47382
PCO: PHACADRAFT_257070
SHS: STEHIDRAFT_102924
HIR: HETIRDRAFT_122733 HETIRDRAFT_157468
PSQ: PUNSTDRAFT_114331
ADL: AURDEDRAFT_137746 AURDEDRAFT_144754 AURDEDRAFT_167218
FME: FOMMEDRAFT_112538 FOMMEDRAFT_92115
GTR: GLOTRDRAFT_35605
LBC: LACBIDRAFT_186573 LACBIDRAFT_232929
CCI: CC1G_09151
PCUB: JR316_0011523
MRR: Moror_1938 Moror_4747
MORE: E1B28_000097 E1B28_002394
CPUT: CONPUDRAFT_112134 CONPUDRAFT_123858 CONPUDRAFT_155151
SLA: SERLADRAFT_354456 SERLADRAFT_446026
UMA: UMAG_05038 UMAG_06433
PFP: PFL1_01803
PGR: PGTG_03133
MLR: MELLADRAFT_22597 MELLADRAFT_37617 MELLADRAFT_43430 MELLADRAFT_48408
MBR: MONBRDRAFT_28085 MONBRDRAFT_35405
SRE: PTSG_01035 PTSG_05228 PTSG_07829 PTSG_08530 PTSG_08937 PTSG_12751
DDI: DDB_G0267924 DDB_G0277269(ionA)
DPP: DICPUDRAFT_42780 DICPUDRAFT_47441 DICPUDRAFT_90846
DFA: DFA_05945(ionA) DFA_09533 DFA_09785
ACAN: ACA1_203720
TET: TTHERM_00049030 TTHERM_00061570 TTHERM_00245100 TTHERM_00266610 TTHERM_00268190 TTHERM_00355800 TTHERM_00365390 TTHERM_00365450 TTHERM_00420880 TTHERM_00420900 TTHERM_00508970 TTHERM_00508990 TTHERM_00643550 TTHERM_00700900 TTHERM_00840060 TTHERM_00854430 TTHERM_00855430 TTHERM_00856430 TTHERM_00989440 TTHERM_01149330 TTHERM_01150350
PTM: GSPATT00000481001 GSPATT00006140001 GSPATT00013152001 GSPATT00014599001 GSPATT00015926001 GSPATT00015953001 GSPATT00021041001 GSPATT00022945001 GSPATT00026301001 GSPATT00030416001 GSPATT00032952001 GSPATT00033380001 PTMB.66
SMIN: v1.2.028598.t1(symbB.v1.2.028598.t1)
AAF: AURANDRAFT_70232
PIF: PITG_14384 PITG_16061
PSOJ: PHYSODRAFT_245875 PHYSODRAFT_495494
SPAR: SPRG_00285 SPRG_13744 SPRG_17035
NGR: NAEGRDRAFT_258 NAEGRDRAFT_30663 NAEGRDRAFT_62984
GLA: GL50803_0096670
PLAL: FXN65_14000
METU: GNH96_00745
MDN: JT25_001620
MDH: AYM39_09255
MKO: MKLM6_1962
METL: U737_16210
MELL: IVG45_13075
MMAI: sS8_5209
MOZ: MoryE10_33760
TCX: Tcr_1065
HMAR: HVMH_1068
CYQ: Q91_1618
CZA: CYCME_0842
CYY: CPC19_04760
TXA: HQN79_01750
TSE: THMIRHAS_22680
ALV: Alvin_1341
TAU: Tola_1844
PSE: NH8B_2287
NLC: EBAPG3_004480 EBAPG3_006755
SHD: SUTH_00139
DOE: DENOEST_3874
SLT: Slit_1198
GCA: Galf_2615
FKU: FGKAn22_02350
SEME: MIZ01_1762
SDR: SCD_n00861
SULF: CAP31_05345
SLAC: SKTS_18720
ARES: IWH25_01745
NIV: JY500_21380
ABRE: pbN1_39610
APET: ToN1_09380
DAR: Daro_1851
DDEN: KI615_06060
QAU: KI612_07915
AZA: AZKH_2708
AZI: AzCIB_2740
AZR: CJ010_03550
APP: CAP2UW1_2799
SMAX: FJR03_05340
SKU: Sulku_0835
SULR: B649_05270
GUR: Gura_3300
GEO: Geob_1849
PCA: Pcar_2279
PPD: Ppro_1564
DPR: Despr_2116
SAT: SYN_02485
MGY: MGMSRv2__1657
MGRY: MSR1_15930
MAGX: XM1_2567
MAGN: WV31_04655
MAES: Ga0123461_0878
MFN: Ga0123462_1448
LBI: LEPBI_I2749
LBF: LBF_2665
TPX: Turpa_2494
ABAC: LuPra_03991(yloB_2)
SUL: SYO3AOP1_0704
TYE: THEYE_A0525
NDE: NIDE3786
NMV: NITMOv2_3862
NIO: NITINOP_0570
TOP: TOPB45_1027
CTHI: THC_0765
MOX: DAMO_0992
MBA: Mbar_A1053
MBW: MSBRW_3669
MBAR: MSBR2_3266
MBAK: MSBR3_3261
MAC: MA_4378
MMA: MM_1069
MMAZ: MmTuc01_1100
MMJ: MSMAS_0232
MMAC: MSMAC_0238
MVC: MSVAZ_0218 MSVAZ_0627
MEK: MSKOL_0212 MSKOL_0609
MLS: MSLAZ_2966
METM: MSMTP_0268
MEF: MSWH1_0533
MEQ: MSWHS_0548
MSJ: MSSAC_4063
MSZ: MSSIH_3599
MSW: MSSIT_3652
MHOR: MSHOH_0294
MBU: Mbur_0431
MELO: J7W08_03135
MHAZ: BHR79_09450
MZH: Mzhil_1847
MPY: Mpsy_0778
MZI: HWN40_04795
MHZ: Metho_1783
MAQE: RJ40_01410
 » show all
Reference
1  [PMID:13412736]
  Authors
SKOU JC.
  Title
The influence of some cations on an adenosine triphosphatase from peripheral nerves.
  Journal
Biochim Biophys Acta 23:394-401 (1957)
DOI:10.1016/0006-3002(57)90343-8
Reference
2  [PMID:14284759]
  Authors
POST RL, SEN AK, ROSENTHAL AS.
  Title
A PHOSPHORYLATED INTERMEDIATE IN ADENOSINE TRIPHOSPHATE-DEPENDENT SODIUM AND POTASSIUM TRANSPORT ACROSS KIDNEY MEMBRANES.
  Journal
J Biol Chem 240:1437-45 (1965)
Reference
3  [PMID:2166689]
  Authors
Skou JC.
  Title
The fourth Datta lecture. The energy coupled exchange of Na+ for K+ across the cell membrane. The Na+, K(+)-pump.
  Journal
FEBS Lett 268:314-24 (1990)
DOI:10.1016/0014-5793(90)81278-V
Reference
4  [PMID:26205423]
  Authors
Castillo JP, Rui H, Basilio D, Das A, Roux B, Latorre R, Bezanilla F, Holmgren M
  Title
Mechanism of potassium ion uptake by the Na(+)/K(+)-ATPase.
  Journal
Nat Commun 6:7622 (2015)
DOI:10.1038/ncomms8622
Other DBs
ExplorEnz - The Enzyme Database: 7.2.2.13
IUBMB Enzyme Nomenclature: 7.2.2.13
ExPASy - ENZYME nomenclature database: 7.2.2.13
BRENDA, the Enzyme Database: 7.2.2.13

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