KEGG   DRUG: Cephalexin
Entry
D00906                      Drug                                   
Name
Cephalexin (USP);
Cephalexin monohydrate;
Cefalexin;
Keftab (TN);
Panixine disperdose (TN)
Product
  Generic
CEPHALEXIN (A-S Medication Solutions), CEPHALEXIN (A-S Medication Solutions), CEPHALEXIN (A-S Medication Solutions), CEPHALEXIN (A-S Medication Solutions), CEPHALEXIN (A-S Medication Solutions), CEPHALEXIN (A-S Medication Solutions), CEPHALEXIN (A-S Medication Solutions), CEPHALEXIN (A-S Medication Solutions), CEPHALEXIN (A-S Medication Solutions), CEPHALEXIN (A-S Medication Solutions), CEPHALEXIN (A-S Medication Solutions), CEPHALEXIN (A-S Medication Solutions), CEPHALEXIN (ADVANCED RX PHARMACY OF TENNESSEE), CEPHALEXIN (ADVANCED RX PHARMACY OF TENNESSEE), CEPHALEXIN (AMELLA PHARMA), CEPHALEXIN (Advanced Rx Pharmacy of Tennessee), CEPHALEXIN (American Health Packaging), CEPHALEXIN (Ascend Laboratories), CEPHALEXIN (Ascend Laboratories), CEPHALEXIN (Asclemed USA), CEPHALEXIN (Aurobindo Pharma Limited), CEPHALEXIN (AvKARE), CEPHALEXIN (AvPAK), CEPHALEXIN (Bi-Coastal Pharma International LLC), CEPHALEXIN (Bryant Ranch Prepack), CEPHALEXIN (Bryant Ranch Prepack), CEPHALEXIN (Bryant Ranch Prepack), CEPHALEXIN (Bryant Ranch Prepack), CEPHALEXIN (Bryant Ranch Prepack), CEPHALEXIN (Bryant Ranch Prepack), CEPHALEXIN (Bryant Ranch Prepack), CEPHALEXIN (Bryant Ranch Prepack), CEPHALEXIN (Bryant Ranch Prepack), CEPHALEXIN (Bryant Ranch Prepack), CEPHALEXIN (Bryant Ranch Prepack), CEPHALEXIN (Bryant Ranch Prepack), CEPHALEXIN (Bryant Ranch Prepack), CEPHALEXIN (Bryant Ranch Prepack), CEPHALEXIN (Bryant Ranch Prepack), CEPHALEXIN (Bryant Ranch Prepack), CEPHALEXIN (Bryant Ranch Prepack), CEPHALEXIN (Bryant Ranch Prepack), CEPHALEXIN (Bryant Ranch Prepack), CEPHALEXIN (Bryant Ranch Prepack), CEPHALEXIN (Bryant Ranch Prepack), CEPHALEXIN (Bryant Ranch Prepack), CEPHALEXIN (Chartwell RX), CEPHALEXIN (Cronus Pharma LLC), CEPHALEXIN (DIRECT RX), CEPHALEXIN (DIRECT RX), CEPHALEXIN (Denton Pharma), CEPHALEXIN (Denton Pharma), CEPHALEXIN (Denton Pharma), CEPHALEXIN (Direct_Rx), CEPHALEXIN (Direct_Rx), CEPHALEXIN (Direct_Rx), CEPHALEXIN (Direct_Rx), CEPHALEXIN (Direct_Rx), CEPHALEXIN (Hikma Pharmaceuticals USA), CEPHALEXIN (Hikma Pharmaceuticals USA), CEPHALEXIN (Lupin Pharmaceuticals), CEPHALEXIN (Lupin Pharmaceuticals), CEPHALEXIN (Medsource Pharmaceuticals), CEPHALEXIN (Northwind Pharmaceuticals), CEPHALEXIN (NuCare Pharmaceuticals), CEPHALEXIN (NuCare Pharmaceuticals), CEPHALEXIN (NuCare Pharmaceuticals), CEPHALEXIN (NuCare Pharmaceuticals), CEPHALEXIN (NuCare Pharmaceuticals), CEPHALEXIN (NuCare Pharmaceuticals), CEPHALEXIN (NuCare Pharmaceuticals), CEPHALEXIN (NuCare Pharmaceuticals), CEPHALEXIN (NuCare Pharmaceuticals), CEPHALEXIN (NuCare Pharmaceuticals), CEPHALEXIN (NuCare Pharmaceuticals), CEPHALEXIN (NuCare Pharmaceuticals), CEPHALEXIN (NuCare Pharmaceuticals), CEPHALEXIN (NuCare Pharmaceuticals), CEPHALEXIN (NuCare Pharmaceuticals), CEPHALEXIN (NuCare Pharmaceuticals), CEPHALEXIN (NuCarePharmaceuticals), CEPHALEXIN (PD-Rx Pharmaceuticals), CEPHALEXIN (PD-Rx Pharmaceuticals), CEPHALEXIN (PD-Rx Pharmaceuticals), CEPHALEXIN (PD-Rx Pharmaceuticals), CEPHALEXIN (PD-Rx Pharmaceuticals), CEPHALEXIN (PD-Rx Pharmaceuticals), CEPHALEXIN (PD-Rx Pharmaceuticals), CEPHALEXIN (PD-Rx Pharmaceuticals), CEPHALEXIN (PharmPak), CEPHALEXIN (PharmPak), CEPHALEXIN (Pharma-C), CEPHALEXIN (Preferred Pharmaceuticals), CEPHALEXIN (Preferred Pharmaceuticals), CEPHALEXIN (Preferred Pharmaceuticals), CEPHALEXIN (Preferred Pharmaceuticals), CEPHALEXIN (Preferred Pharmaceuticals), CEPHALEXIN (Preferred Pharmaceuticlas), CEPHALEXIN (Proficient Rx LP), CEPHALEXIN (Proficient Rx LP), CEPHALEXIN (Proficient Rx LP), CEPHALEXIN (Proficient Rx LP), CEPHALEXIN (QPharma), CEPHALEXIN (QPharma), CEPHALEXIN (QPharma), CEPHALEXIN (QPharma), CEPHALEXIN (REMEDYREPACK), CEPHALEXIN (REMEDYREPACK), CEPHALEXIN (REMEDYREPACK), CEPHALEXIN (REMEDYREPACK), CEPHALEXIN (REMEDYREPACK), CEPHALEXIN (RPK Pharmaceuticals), CEPHALEXIN (RPK Pharmaceuticals), CEPHALEXIN (RPK Pharmaceuticals), CEPHALEXIN (RedPharm Drug), CEPHALEXIN (RedPharm Drug), CEPHALEXIN (TWi Pharmaceuticals), CEPHALEXIN (Teva Pharmaceuticals USA), CEPHALEXIN (Teva Pharmaceuticals USA), CEPHALEXIN ORAL SUSP (DIRECTRX)
Formula
C16H17N3O4S. H2O
Exact mass
365.1045
Mol weight
365.4042
Structure
Simcomp
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01714  Cephalosporin skeleton group
   DG01488  Cephem
 DG01774  First-generation cephalosporin
Remark
Same as: C08099
ATC code: J01DB01
Chemical structure group: DG00548
Product (DG00548): D00263<JP> D00906<US>
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
Target
penicillin binding protein
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Structure map
map07013  Cephalosporins - oral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DB First-generation cephalosporins
     J01DB01 Cefalexin
      D00906  Cephalexin (USP) <US>
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Cephalosporins
   Cephalexin
    D00906  Cephalexin (USP)
Drug groups [BR:br08330]
 Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01714  Cephalosporin skeleton group
    DG01488  Cephem
     DG00548  Cephalexin
      D00906  Cephalexin
  DG01774  First-generation cephalosporin
   DG00548  Cephalexin
    D00906  Cephalexin
Drug classes [BR:br08332]
 Antibacterial
  DG01488  Cephem
   D00906  Cephalexin
Antimicrobials [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   First-generation cephalosporin
    D00906  Cephalexin (USP) <US>
Drug groups [BR:br08330]
 Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01714  Cephalosporin skeleton group
    DG01488  Cephem
     DG00548  Cephalexin
  DG01774  First-generation cephalosporin
   DG00548  Cephalexin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   First-generation cephalosporin
    DG00548  Cefalexin
Other DBs
CAS: 23325-78-2
PubChem: 47205806
ChEBI: 3535
LigandBox: D00906
NIKKAJI: J2.194.820I
KCF data

ATOM        25
            1   C1y C    29.3164  -14.8915
            2   N1y N    29.3164  -16.2906
            3   C2y C    30.5281  -16.9900
            4   C2y C    31.7398  -16.2906
            5   C1x C    31.7398  -14.8915
            6   S2x S    30.5281  -14.1919
            7   C1y C    27.9173  -14.8915
            8   C5x C    27.9173  -16.2906
            9   N1b N    26.7057  -14.1919
            10  C5a C    25.4938  -14.8915
            11  O5a O    25.4938  -16.2906
            12  O5x O    26.7057  -16.9900
            13  C1c C    24.2822  -14.1919
            14  C1a C    32.9701  -17.0012
            15  C6a C    30.5281  -18.3890
            16  O6a O    29.2996  -19.0984
            17  O6a O    31.7228  -19.0789
            18  C8y C    23.0510  -14.9031
            19  C8x C    21.8409  -14.2044
            20  C8x C    20.6307  -14.9031
            21  C8x C    20.6307  -16.3005
            22  C8x C    21.8409  -16.9992
            23  C8x C    23.0510  -16.3005
            24  N1a N    24.2822  -12.7883
            25  O0  O    34.7200  -15.0500
BOND        26
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16    3  15 1
            17   15  16 2
            18   15  17 1
            19   13  18 1
            20   18  19 2
            21   19  20 1
            22   20  21 2
            23   21  22 1
            24   22  23 2
            25   18  23 1
            26   13  24 1 #Up

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