| Entry |
|
|---|
| Name |
Cefpodoxime proxetil (JP18/USP);
Vantin (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C21H27N5O9S2
|
|---|
| Exact mass |
557.125
|
|---|
| Mol weight |
557.5972
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Therapeutic category: | 6132 |
| Product (DG00582): | D00920<JP/US> |
|
|---|
| Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
|---|
| Comment |
Active form of prodrug: Cefpodoxime [DR: D07650]
|
|---|
| Target |
penicillin binding protein |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DD Third-generation cephalosporins
J01DD13 Cefpodoxime
D00920 Cefpodoxime proxetil (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
Antibacterials
Beta-lactam, Cephalosporins
Cefpodoxime
D00920 Cefpodoxime proxetil (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
61 Antibiotics
613 Acting mainly on gram-positive and gram-negative bacteria
6132 Cephem antibioitics
D00920 Cefpodoxime proxetil (JP18/USP)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00582 Cefpodoxime
D00920 Cefpodoxime proxetil
DG01776 Third-generation cephalosporin
DG00582 Cefpodoxime
D00920 Cefpodoxime proxetil
DG01804 Oxyimino beta-lactam
DG00582 Cefpodoxime
D00920 Cefpodoxime proxetil
Drug classes [BR:br08332]
Antibacterial
DG01488 Cephem
D00920 Cefpodoxime proxetil
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Third-generation cephalosporin
D00920 Cefpodoxime proxetil (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00920 Cefpodoxime proxetil
D00920 Cefpodoxime proxetil tablets
D00920 Cefpodoxime proxetil for syrup
Prodrugs [br08324.html]
D00920
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00582 Cefpodoxime
DG01776 Third-generation cephalosporin
DG00582 Cefpodoxime
DG01804 Oxyimino beta-lactam
DG00582 Cefpodoxime
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Third-generation cephalosporin
DG00582 Cefpodoxime
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 37
1 C1y C 31.5842 -17.3805
2 N1y N 31.5842 -18.7567
3 C2y C 32.7540 -19.4449
4 C2y C 33.9239 -18.7567
5 C1x C 33.9239 -17.3805
6 S2x S 32.7540 -16.6923
7 C1y C 30.2079 -17.3805
8 C5x C 30.2079 -18.7567
9 N1b N 28.9691 -16.6923
10 C5a C 27.7993 -17.3805
11 O5a O 27.7993 -18.7567
12 O5x O 28.9691 -19.4449
13 C2c C 26.6294 -16.6923
14 C1b C 35.1627 -19.4449
15 C8y C 25.3906 -17.3805
16 C8x C 24.3584 -16.5546
17 S2x S 23.1886 -17.3116
18 C8y C 23.6015 -18.6879
19 N5x N 24.9777 -18.6879
20 N2b N 26.6294 -15.3158
21 C7a C 32.7540 -21.7845
22 O7a O 33.9239 -22.4727
23 O6a O 31.5154 -22.4727
24 N1a N 22.7757 -19.7889
25 O2a O 36.3407 -18.7387
26 C1a C 37.5407 -19.4054
27 C1c C 35.1193 -21.7954
28 O7a O 36.2775 -22.4768
29 C1a C 35.0621 -20.4067
30 C7a C 37.4637 -21.8047
31 O7a O 38.6645 -22.5115
32 C1c C 39.8522 -21.8393
33 O6a O 37.4747 -20.4063
34 C1a C 41.0316 -22.5338
35 C1a C 39.8639 -20.4752
36 O2a O 27.8164 -14.6368
37 C1a C 27.8164 -13.2368
BOND 39
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1
8 7 8 1
9 2 8 1
10 7 9 1 #Up
11 9 10 1
12 10 11 2
13 8 12 2
14 10 13 1
15 4 14 1
16 13 15 1
17 15 16 2
18 16 17 1
19 17 18 1
20 18 19 2
21 15 19 1
22 13 20 2
23 3 21 1
24 21 22 1
25 21 23 2
26 18 24 1
27 14 25 1
28 25 26 1
29 22 27 1
30 27 28 1
31 27 29 1
32 28 30 1
33 30 31 1
34 31 32 1
35 30 33 2
36 32 34 1
37 32 35 1
38 20 36 1
39 36 37 1
|
|---|
