KEGG   DRUG: Dextran sulfate sodium sulfur 5
Entry
D03343                      Drug                                   

Name
Dextran sulfate sodium sulfur 5 (JP18);
Dextran sulfate sodium sulfur 18 (JP18);
MDS (TN)
Remark
Therapeutic category: 2189
ATC code: B05AA05
Chemical structure group: DG00180
Product (DG00180): D02141<US> D03343<JP> D06539<US>
Efficacy
Antidyslipidemia (hypertriglyceridemic), Lipoprotein lipase (LPL) activator
Target
LPL [HSA:4023] [KO:K01059]
LIPC [HSA:3990] [KO:K22283]
  Pathway
hsa00561  Glycerolipid metabolism
hsa03320  PPAR signaling pathway
hsa04979  Cholesterol metabolism
Interaction
Structure map
map07052  Antidyslipidemic agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
   B05A BLOOD AND RELATED PRODUCTS
    B05AA Blood substitutes and plasma protein fractions
     B05AA05 Dextran
      D03343  Dextran sulfate sodium sulfur 5 (JP18) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   218  Hyperlipidemia agents
    2189  Others
     D03343  Dextran sulfate sodium sulfur 5 (JP18); Dextran sulfate sodium sulfur 18 (JP18)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases (EC3)
   Carboxylic-ester hydrolases
    LIPC
     D03343  Dextran sulfate sodium sulfur 5 (JP18) <JP>
    LPL
     D03343  Dextran sulfate sodium sulfur 5 (JP18) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D03343  Dextran sulfate sodium sulfur 5
  D03343  Dextran sulfate sodium sulfur 18
Other DBs
PubChem: 17397493

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