KEGG   DRUG: Dexetimide
Entry
D03711                      Drug                                   
Name
Dexetimide (USAN/INN);
(+)-Benzetimide
Formula
C23H26N2O2
Exact mass
362.1994
Mol weight
362.4647
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
  DG01745  Anticholinergic antiparkinson agent
Remark
ATC code: N04AA08
Chemical structure group: DG00856
Efficacy
Antiparkinsonian, Muscarinic acetylcholine receptor antagonist
Target
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04A ANTICHOLINERGIC AGENTS
    N04AA Tertiary amines
     N04AA08 Dexetimide
      D03711  Dexetimide (USAN/INN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01491  Muscarinic cholinergic receptor antagonist
   DG01745  Anticholinergic antiparkinson agent
    DG00856  Dexetimide
     D03711  Dexetimide
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D03711  Dexetimide (USAN/INN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01491  Muscarinic cholinergic receptor antagonist
   DG01745  Anticholinergic antiparkinson agent
    DG00856  Dexetimide
Other DBs
CAS: 21888-98-2
PubChem: 17397802
LigandBox: D03711
NIKKAJI: J11.153H
KCF data

ATOM        27
            1   C1z C    16.3100  -15.8200
            2   C1x C    16.3100  -17.1500
            3   C1x C    15.1900  -17.8500
            4   C5x C    14.0000  -17.1500
            5   N1x N    14.0000  -15.8200
            6   C5x C    15.1900  -15.1200
            7   O5x O    15.1900  -13.7900
            8   O5x O    12.8100  -17.8500
            9   C8y C    18.4800  -17.1500
            10  C8x C    20.9300  -17.1500
            11  C8x C    20.9300  -18.5500
            12  C8x C    19.7400  -19.2500
            13  C8x C    18.4800  -18.5500
            14  C8x C    19.7400  -16.4500
            15  C1y C    17.5000  -15.1200
            16  C1x C    17.5000  -13.7900
            17  C1x C    18.6900  -13.0900
            18  N1y N    19.8100  -13.7900
            19  C1x C    19.8100  -15.1200
            20  C1x C    18.6900  -15.8200
            21  C1b C    21.0000  -13.0900
            22  C8y C    22.1900  -13.7900
            23  C8x C    23.3100  -13.0900
            24  C8x C    24.5000  -13.7900
            25  C8x C    24.5000  -15.1200
            26  C8x C    23.3800  -15.8200
            27  C8x C    22.1900  -15.1200
BOND        30
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     6   7 2
            8     4   8 2
            9    10  11 2
            10   11  12 1
            11   12  13 2
            12   13   9 1
            13    9  14 2
            14   10  14 1
            15    1   9 1 #Up
            16   15  16 1
            17   16  17 1
            18   17  18 1
            19   18  19 1
            20   19  20 1
            21   15  20 1
            22   18  21 1
            23   21  22 1
            24   22  23 2
            25   23  24 1
            26   24  25 2
            27   25  26 1
            28   26  27 2
            29   22  27 1
            30    1  15 1 #Down

» Japanese version   » Back

DBGET integrated database retrieval system