KEGG   DRUG: Chloramphenicol stearate
Entry
D07674                      Drug                                   

Name
Chloramphenicol stearate;
Quemicetina (TN)
Formula
C29H46Cl2N2O6
Exact mass
588.2733
Mol weight
589.5913
Structure
Simcomp
Class
Antibacterial
 DG01576  Amphenicol type antibacterial
Remark
ATC code: D06AX02 D10AF03 G01AA05 J01BA01 S01AA01 S02AA01 S03AA08
Chemical structure group: DG00399
Product (DG00399): D00104<JP> D02185<JP/US>
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Comment
Amphenicol derivative
Active form of prodrug: Chloramphenicol [DR:D00104]
Target
50S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
   D06A ANTIBIOTICS FOR TOPICAL USE
    D06AX Other antibiotics for topical use
     D06AX02 Chloramphenicol
      D07674  Chloramphenicol stearate
  D10 ANTI-ACNE PREPARATIONS
   D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE
    D10AF Antiinfectives for treatment of acne
     D10AF03 Chloramphenicol
      D07674  Chloramphenicol stearate
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
   G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
    G01AA Antibiotics
     G01AA05 Chloramphenicol
      D07674  Chloramphenicol stearate
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01B AMPHENICOLS
    J01BA Amphenicols
     J01BA01 Chloramphenicol
      D07674  Chloramphenicol stearate
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA01 Chloramphenicol
      D07674  Chloramphenicol stearate
  S02 OTOLOGICALS
   S02A ANTIINFECTIVES
    S02AA Antiinfectives
     S02AA01 Chloramphenicol
      D07674  Chloramphenicol stearate
  S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
   S03A ANTIINFECTIVES
    S03AA Antiinfectives
     S03AA08 Chloramphenicol
      D07674  Chloramphenicol stearate
Drug groups [BR:br08330]
 Antibacterial
  DG01576  Amphenicol type antibacterial
   DG00399  Chloramphenicol
    D07674  Chloramphenicol stearate
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Amphenicol
    D07674  Chloramphenicol stearate
Prodrugs [br08324.html]
 D07674
Drug groups [BR:br08330]
 Antibacterial
  DG01576  Amphenicol type antibacterial
   DG00399  Chloramphenicol
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Amphenicol
    DG00399  Chloramphenicol
Prodrugs [br08324.html]
 DG00399
Other DBs
CAS: 16255-48-4
PubChem: 51091976
ChEBI: 177426
LigandBox: D07674
NIKKAJI: J286.850D
KCF data

ATOM        39
            1   C8y C     8.9879  -15.5006
            2   C1c C     8.9879  -16.9031
            3   C8x C     7.7958  -14.7994
            4   C8x C    10.2501  -14.7994
            5   C1c C    10.2501  -17.6043
            6   O1a O     7.7958  -17.6043
            7   C8x C     7.7958  -13.3268
            8   C8x C    10.2501  -13.3268
            9   N1b N    11.4422  -16.9031
            10  C1b C    10.2500  -19.0068
            11  C8y C     8.9879  -12.6255
            12  C5a C    12.6343  -17.6043
            13  O7a O     9.0579  -19.7081
            14  N2b N     8.9879  -11.2231 #+
            15  C1c C    13.8966  -16.9031
            16  O5a O    12.6343  -19.0068
            17  O3a O     7.7958  -10.5218
            18  O3a O    10.2501  -10.5218 #-
            19  X   Cl   15.0887  -17.6043
            20  X   Cl   13.8966  -15.5006
            21  C7a C     9.0579  -21.1105
            22  O6a O     7.8658  -21.8118
            23  C1b C    10.2500  -21.8118
            24  C1b C    11.5122  -21.1105
            25  C1b C    12.7043  -21.8118
            26  C1b C    13.8964  -21.1105
            27  C1b C    15.0885  -21.8118
            28  C1b C    16.3508  -21.1105
            29  C1b C    17.5429  -21.8118
            30  C1b C    18.7350  -21.1105
            31  C1b C    19.9271  -21.8118
            32  C1b C    21.1192  -21.1105
            33  C1b C    22.3814  -21.8118
            34  C1b C    23.5735  -21.1807
            35  C1b C    24.7657  -21.8118
            36  C1b C    25.9578  -21.1807
            37  C1b C    27.1499  -21.8118
            38  C1b C    28.3379  -21.0665
            39  C1a C    29.5696  -21.7184
BOND        39
            1    15  19 1
            2    15  20 1
            3     8  11 1
            4    13  21 1
            5     1   2 1
            6    21  22 2
            7     1   3 2
            8    21  23 1
            9     1   4 1
            10   23  24 1
            11    2   5 1
            12   24  25 1
            13    2   6 1 #Down
            14   25  26 1
            15    3   7 1
            16   26  27 1
            17    4   8 2
            18   27  28 1
            19    5   9 1
            20   28  29 1
            21    5  10 1
            22   29  30 1
            23    7  11 2
            24   30  31 1
            25    9  12 1
            26   31  32 1
            27   10  13 1
            28   32  33 1
            29   11  14 1
            30   33  34 1
            31   12  15 1
            32   34  35 1
            33   12  16 2
            34   35  36 1
            35   14  17 2
            36   36  37 1
            37   14  18 1
            38   37  38 1
            39   38  39 1

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