KEGG   DRUG: Troriluzole
Entry
D11414                      Drug                                   

Name
Troriluzole (USAN)
Formula
C15H16F3N5O4S
Exact mass
419.0875
Mol weight
419.3789
Structure
Remark
Chemical structure group: DG03011
Efficacy
Neuroprotectant
Comment
Treatment of spinocerebellar ataxia (SCA)
Target
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04724  Glutamatergic synapse
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   Glutamate (ionotropic), non-NMDA
    GRIA
     D11414  Troriluzole (USAN)
    GRIK
     D11414  Troriluzole (USAN)
   Glutamate (ionotropic), NMDA
    GRIN (NMDAR)
     D11414  Troriluzole (USAN)
Other DBs
CAS: 1926203-09-9
PubChem: 384585392
ChEMBL: CHEMBL4297586
KCF data

ATOM        28
            1   C1d C     7.8572  -27.3177
            2   O2a O     9.0486  -26.6169
            3   X   F     6.6658  -26.6169
            4   X   F     7.8572  -28.7193
            5   X   F     6.6658  -28.0185
            6   C8y C    10.3100  -27.3177
            7   C8x C    11.5014  -26.6169
            8   C8x C    10.3100  -28.7193
            9   C8y C    12.6927  -27.3177
            10  C8x C    11.5014  -29.4201
            11  C8y C    12.6927  -28.7193
            12  S2x S    14.0242  -26.8271
            13  N5x N    14.0242  -29.1398
            14  C8y C    14.8652  -27.9484
            15  N1b N    16.2668  -27.9484
            16  C5a C    16.9518  -29.1355
            17  C1b C    18.3399  -29.1357
            18  O5a O    16.2554  -30.3412
            19  N1c N    19.0469  -27.9116
            20  C5a C    20.4399  -27.9119
            21  C1a C    18.3533  -26.7100
            22  C1b C    21.1324  -26.7132
            23  O5a O    21.1475  -29.1381
            24  N1b N    22.5397  -26.7135
            25  C5a C    23.2288  -25.5211
            26  C1b C    24.6397  -25.5214
            27  O5a O    22.5443  -24.3351
            28  N1a N    25.3278  -24.3306
BOND        29
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1
            5     2   6 1
            6     6   7 2
            7     6   8 1
            8     7   9 1
            9     8  10 2
            10    9  11 2
            11    9  12 1
            12   11  13 1
            13   12  14 1
            14   14  15 1
            15   10  11 1
            16   13  14 2
            17   15  16 1
            18   16  17 1
            19   16  18 2
            20   17  19 1
            21   19  20 1
            22   19  21 1
            23   20  22 1
            24   20  23 2
            25   22  24 1
            26   24  25 1
            27   25  26 1
            28   25  27 2
            29   26  28 1

» Japanese version   » Back

DBGET integrated database retrieval system