KEGG   DRUG: Bamlanivimab
Entry
D11936                      Drug                                   
Name
Bamlanivimab (USAN);
Bamlanivimab (TN)
Product
  Other
Formula
C6498H10068N1732O2032S46
Exact mass
146348.4884
Mol weight
146438.8437
Sequence
(Heavy chain)
QVQLVQSGAE VKKPGSSVKV SCKASGGTFS NYAISWVRQA PGQGLEWMGR IIPILGIANY
AQKFQGRVTI TADKSTSTAY MELSSLRSED TAVYYCARGY YEARHYYYYY AMDVWGQGTA
VTVSSASTKG PSVFPLAPSS KSTSGGTAAL GCLVKDYFPE PVTVSWNSGA LTSGVHTFPA
VLQSSGLYSL SSVVTVPSSS LGTQTYICNV NHKPSNTKVD KRVEPKSCDK THTCPPCPAP
ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR
EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP
PSREEMTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV
DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGK
(Light chain)
DIQMTQSPSS LSASVGDRVT ITCRASQSIS SYLSWYQQKP GKAPKLLIYA ASSLQSGVPS
RFSGSGSGTD FTLTITSLQP EDFATYYCQQ SYSTPRTFGQ GTKVEIKRTV AAPSVFIFPP
SDEQLKSGTA SVVCLLNNFY PREAKVQWKV DNALQSGNSQ ESVTEQDSKD STYSLSSTLT
LSKADYEKHK VYACEVTHQG LSSPVTKSFN RGEC
(Disulfide bridge: H22-H96, H152-H208, H228-L214, H234-H'234, H237-H'237H269-H329, H375-H433, H'22-H'96, H'152-H'208, H'228-L'214, H'269-H'329, H'375-H'433, L23-L88, L134-L194, L'23-L'88, L'134-L'194)
  Type
Peptide
Class
Antiviral
 DG03174  Anti-SARS-CoV-2 agent
Remark
Product: D11936<US>
Efficacy
Antiviral
  Disease
Coronavirus disease 2019 [DS:H02398]
Comment
Monoclonal antibody
Treatment of SARS-CoV-2 infections (COVID-19)
Target
SARS-CoV-2 spike glycoprotein [KO:K24152]
  Pathway
ko03230  Viral genome structure
ko05171  Coronavirus disease - COVID-19
Brite
Drug groups [BR:br08330]
 Antiviral
  DG03174  Anti-SARS-CoV-2 agent
   D11936  Bamlanivimab
Drug classes [BR:br08332]
 Antiviral
  DG03174  Anti-SARS-CoV-2 agent
   D11936  Bamlanivimab
Antimicrobials [BR:br08307]
 Antivirals
  Entry, fusion or uncoating inhibitor
   Coronavirus spike protein
    D11936  Bamlanivimab (USAN) <US>
Other DBs
CAS: 2423943-37-5

» Japanese version   » Back

DBGET integrated database retrieval system