KEGG   DRUG: Plutavimab
Entry
D12199                      Drug                                   
Name
Plutavimab (USAN)
Formula
C6372H9888N1706O2007S46
Exact mass
143891.1271
Mol weight
143979.9071
Sequence
(Heavy chain)
EVQLVESGGG LIQPGGSLRL SCAASGFTVS SNYMSWVRQA PGKGLEWVSI IYPGGSTEYA
DSVKGRFTIS RDNSRNTLYL QMNSLRAEDT AVYYCARELG YYGMDVWGQG TTVTVSSAST
KGPSVFPLAP SSKSTSGGTA ALGCLVKDYF PEPVTVSWNS GALTSGVHTF PAVLQSSGLY
SLSSVVTVPS SSLGTQTYIC NVNHKPSNTK VDKRVEPKSC DKTHTCPPCP APEAAGGPSV
FLFPPKPKDT LMISRTPEVT CVVVDVSHED PEVKFNWYVD GVEVHNAKTK PREEQYNSTY
RVVSVLTVLH QDWLNGKEYK CKVSNKALPA PIEKTISKAK GQPREPQVYT LPPSREEMTK
NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSKL TVDKSRWQQG
NVFSCSVMHE ALHNHYTQKS LSLSPGK
(Light chain)
DIQMTQSPSS VSASVGDRVT ITCRASQGIS TWLVWYQQKP GKAPNLLIYG ASSLQSGVPS
RFSGSGSGTD FTLTISSLQP EDFATYYCQQ ANAYPYTFGQ GTKLEIKRTV AAPSVFIFPP
SDEQLKSGTA SVVCLLNNFY PREAKVQWKV DNALQSGNSQ ESVTEQDSKD STYSLSSTLT
LSKADYEKHK VYACEVTHQG LSSPVTKSFN RGEC
(Disulfide bridge: H22-H95, H220-L214, H144-H200, H226-H'226, H229-H'229, H261-H321, H367-H425, H'22-H'95, H'220-L'214, H'144-H'200, H'261-H'321, H'367-H'425, L23-L88, L134-L194, L'23-L'88, L'134-L'194)
  Type
Peptide
Class
Antiviral
 DG03174  Anti-SARS-CoV-2 agent
Efficacy
Antiviral
Comment
Monoclonal antibody
Treatment of SARS-CoV-2 infection
Target
SARS-CoV-2 spike glycoprotein [KO:K24152]
  Pathway
ko03230  Viral genome structure
ko05171  Coronavirus disease - COVID-19
Brite
Drug groups [BR:br08330]
 Antiviral
  DG03174  Anti-SARS-CoV-2 agent
   D12199  Plutavimab
Antimicrobials [BR:br08307]
 Antivirals
  Entry, fusion or uncoating inhibitor
   Coronavirus spike protein
    D12199  Plutavimab (USAN)
Other DBs
CAS: 2529854-88-2

» Japanese version   » Back

DBGET integrated database retrieval system