KEGG   DRUG: Amubarvimab
Entry
D12254                      Drug                                   
Name
Amubarvimab (USAN)
Formula
C6378H9906N1710O2010S40
Exact mass
143893.4325
Mol weight
143981.7492
Sequence
(Heavy chain)
EVQLVESGGG LVQPGGSLRL SCAASGITVS SNYMNWVRQA PGKGLEWVSL IYSGGSTYYA
DSVKGRFTIS RDNSKNTLYL QMNSLRAEDT AVYHCARDLV VYGMDVWGQG TTVTVSSAST
KGPSVFPLAP SSKSTSGGTA ALGCLVKDYF PEPVTVSWNS GALTSGVHTF PAVLQSSGLY
SLSSVVTVPS SSLGTQTYIC NVNHKPSNTK VDKKVEPKSC DKTHTCPPCP APELLGGPSV
FLFPPKPKDT LYITREPEVT CVVVDVSHED PEVKFNWYVD GVEVHNAKTK PREEQYNSTY
RVVSVLTVLH QDWLNGKEYK CKVSNKALPA PIEKTISKAK GQPREPQVYT LPPSRDELTK
NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSKL TVDKSRWQQG
NVFSCSVMHE ALHNHYTQKS LSLSPGK
(Light chain)
EIVLTQSPGT LSLSPGERAT LSCRASQSVS SSYLAWYQQK PGQAPRLLIY GASSRATGIP
DRFSGSGSGT DFTLTISRLE PEDFAVYYCQ QYGSSPTFGQ GTKLEIKRTV AAPSVFIFPP
SDEQLKSGTA SVVCLLNNFY PREAKVQWKV DNALQSGNSQ ESVTEQDSKD STYSLSSTLT
LSKADYEKHK VYACEVTHQG LSSPVTKSFN RGEC
(Disulfide bridge: H22-H95, H114-H200, H220-L214, H226-H'226, H229-H'229, H261-H321, H367-H425, H'22-H'95, H'144-H'200, H'220-L'214, H'261-H'321, H'367-H'425, L23-L89, L134-L194, L'23-L'89, L'134-L'194)
  Type
Peptide
Class
Antiviral
 DG03174  Anti-SARS-CoV-2 agent
Efficacy
Antiviral
Comment
Monoclonal antibody
Treatment of COVID-19
Target
SARS-CoV-2 spike glycoprotein [KO:K24152]
  Pathway
ko03230  Viral genome structure
ko05171  Coronavirus disease - COVID-19
Brite
Drug groups [BR:br08330]
 Antiviral
  DG03174  Anti-SARS-CoV-2 agent
   D12254  Amubarvimab
Antimicrobials [BR:br08307]
 Antivirals
  Entry, fusion or uncoating inhibitor
   Coronavirus spike protein
    D12254  Amubarvimab (USAN)
Other DBs
CAS: 2509447-07-6

» Japanese version   » Back

DBGET integrated database retrieval system