KEGG   DRUG: Ogalvibart
Entry
D12325                      Drug                                   
Name
Ogalvibart (USAN)
Formula
C6450H9934N1718O2012S42
Exact mass
144993.6102
Mol weight
145082.9244
Sequence
(Heavy chain)
QVQLVESGGG VVQPGRSLRL SCAASGFTFS SYAMHWVRQA PGKGLEWVAV IPFDGRNKYY
ADSVTGRFTI SRDNSKNTLY LQMNSLRAED TAVYYCASSS GYLFHSDYWG QGTLVTVSSA
STKGPSVFPL APSSKSTSGG TAALGCLVKD YFPEPVTVSW NSGALTSGVH TFPAVLQSSG
LYSLSSVVTV PSSSLGTQTY ICNVNHKPSN TKVDKRVEPK SCDKTHTCPP CPAPELLGGP
SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS
TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSREEM
TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ
QGNVFSCSVL HEALHSHYTQ KSLSLSPG
(Light chain)
DIQMTQSPST LSASVGDRVT ITCRASQSIS NWLAWFQQKP GKAPKLLIYE ASSLESGVPS
RFSGSGSGTE FTLTISSLQP DDFATYYCQQ YNSYPWTFGQ GTKVEIKRTV AAPSVFIFPP
SDEQLKSGTA SVVCLLNNFY PREAKVQWKV DNALQSGNSQ ESVTEQDSKD STYSLSSTLT
LSKADYEKHK VYACEVTHQG LSSPVTKSFN RGEC
(Disulfide bridge: H22-H96, H146-H202, H222-L214, H228-H'228, H231-H'231, H263-H323, H369-H427, H'22-H'96, H'146-H'202, H'222-L'214, H'263-H'323, H'369-H'427, L23-L88, L134-L194, L'23-L'88, L'134-L'194)
  Type
Peptide
Class
Antiviral
 DG03174  Anti-SARS-CoV-2 agent
Efficacy
Antiviral
Comment
Monoclonal antibody
Treatment of SARS-CoV-2 infection
Target
SARS-CoV-2 spike glycoprotein [KO:K24152]
  Pathway
ko03230  Viral genome structure
ko05171  Coronavirus disease - COVID-19
Brite
Drug groups [BR:br08330]
 Antiviral
  DG03174  Anti-SARS-CoV-2 agent
   D12325  Ogalvibart
Antimicrobials [BR:br08307]
 Antivirals
  Entry, fusion or uncoating inhibitor
   Coronavirus spike protein
    D12325  Ogalvibart (USAN)
Other DBs
CAS: 2599039-60-6

» Japanese version   » Back

DBGET integrated database retrieval system