KEGG   DISEASE: Scrub typhus
Entry
H00324                      Disease                                

Name
Scrub typhus
Description
Scrub typhus, also known as tsutsugamushi disease, is a zoonosis caused by Orientia tsutsugamushi, an obligate intracellular bacterium that is transmitted by the Leptotrombidium species mite. The disease is confined to East Asia and characterized by fever, rash, eschar, pneumonitis, meningitis, and disseminated intravascular coagulation.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by alpha proteobacteria
   H00324  Scrub typhus
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Other bacterial diseases
   Rickettsioses
    1C30  Typhus fever
     H00324  Scrub typhus
Pathogen
Orientia tsutsugamushi [GN:ots ott] (mite-borne typhus)
Comment
Vector: Leptotrombidium deliense, L. fletcheri and L. arenicola
Other DBs
ICD-11: 1C30.3
ICD-10: A75.3
MeSH: D012612
Reference
  Authors
Seong SY, Choi MS, Kim IS
  Title
Orientia tsutsugamushi infection: overview and immune responses.
  Journal
Microbes Infect 3:11-21 (2001)
DOI:10.1016/S1286-4579(00)01352-6
Reference
  Authors
Ge Y, Rikihisa Y
  Title
Subversion of host cell signaling by Orientia tsutsugamushi.
  Journal
Microbes Infect 13:638-48 (2011)
DOI:10.1016/j.micinf.2011.03.003

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